beta-cubebene
10-methyl-4-methylene-7-isopropyl tricyclo(4.4.0.0(1.5))decane
 
Notes:
None found
Synonyms   Articles   Notes   Search
CAS Number: 13744-15-5Picture of molecule
Nikkaji Web: J14.932B
CoE Number: 10989
XlogP3-AA: 4.70 (est)
Molecular Weight: 204.35628000
Formula: C15 H24
EFSA/JECFA Comments: No longer supported by Industry (DG SANCO, 2012).
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Flavis Number: 01.030 (Old)
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to pale yellow solid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 59.00 to  61.00 °C. @ 760.00 mm Hg
Boiling Point: 283.00 to  285.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.014000 mm/Hg @ 25.00 °C. (est)
Flash Point: 235.00 °F. TCC ( 112.78 °C. )
logP (o/w): 6.181 (est)
Soluble in:
 alcohol
 water, 0.07057 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: citrus
Odor Strength: medium
 citrus  fruity  radish  
Odor Description:
at 100.00 %. 
citrus fruity radish
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavoring agents
Recommendation for beta-cubebene usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3900 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 7.0000035.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 5.0000025.00000
Edible ices, including sherbet and sorbet (03.0): 10.0000050.00000
Processed fruit (04.1): 7.0000035.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 10.0000050.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.0000025.00000
Bakery wares (07.0): 10.0000050.00000
Meat and meat products, including poultry and game (08.0): 2.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.0000010.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.0000025.00000
Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 5.0000025.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
Ready-to-eat savouries (15.0): 20.00000100.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
Synonyms   Articles   Notes   Search   Top
Safety References:
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 25, (FGE.25)[1] - Aliphatic and aromatic hydrocarbons from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 78 (FGE.78)[1] - Consideration of Aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25 - Scientific Opinion of the Panel on Food Additives,Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 25Rev1: Aliphatic and aromatic hydrocarbons from chemical group 31
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 78, Revision 1 (FGE.78Rev1): Consideration of aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25Rev2
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 25, Revision 2 (FGE.25Rev2): Aliphatic and aromatic hydrocarbons from chemical group 31
View page or View pdf
Scientific opinion on Flavouring Group Evaluation 25, Revision 3 (FGE.25Rev3): Aliphatic hydrocarbons from chemical group 31
View page or View pdf
EPI System: View
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 93081
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0013744155
Synonyms   Articles   Notes   Search   Top
References:
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 93081
Pubchem (sid): 135049955
Flavornet: 13744-15-5
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
KEGG (GenomeNet): C09648
HMDB (The Human Metabolome Database): HMDB61853
FooDB: FDB004832
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
(Z)-8-tetradecenalFL/FR
aldehydic
(Z)-4-dodecenalFL/FR
2-dodecanoneFL/FR
(Z+E)-2-methyl-2-(4-methyl-3-pentenyl) cyclopropane carbaldehydeFL/FR
1-methyl-4-methyl ethenyl cyclohexene sulfurizedFL/FR
creamy
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
floral
 bursera graveolens wood oilFL/FR
 citronellyl acetateFL/FR
 geranyl tiglateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 neryl isovalerateFL/FR
 styralyl propionateFL/FR
 terpinyl formateFL/FR
fruity
isoamyl 2-methyl butyrateFL/FR
isobutyl 2-methyl butyrateFL/FR
 ethyl citronellateFL/FR
 ethyl isobutyrateFL/FR
 methyl acetoacetateFL/FR
isopropyl isobutyrateFL/FR
(E)-2-undecenalFL/FR
dextro-limonene oxideFL/FR
 phenyl acetaldehyde dimethyl acetalFL/FR
3-phenyl propionaldehydeFL/FR
herbal
2-dodecenalFL/FR
(1S,5R)-myrtenyl acetateFL/FR
waxy
3-decanoneFL/FR
 
For Flavor
 
No flavor group found for these
 bursera graveolens wood oilFL/FR
3-decanoneFL/FR
 dihydronootkatoneFL
(Z)-4-dodecenalFL/FR
 ethyl citronellateFL/FR
3-mercaptooctanalFL
 methyl acetoacetateFL/FR
(Z+E)-2-methyl-2-(4-methyl-3-pentenyl) cyclopropane carbaldehydeFL/FR
3-octyl butyrateFL
isopropyl isobutyrateFL/FR
(Z)-8-tetradecenalFL/FR
dextro-limonene oxideFL/FR
citrus
 citrus enhancerFL
 dehydronootkatoneFL
1-methyl-4-methyl ethenyl cyclohexene sulfurizedFL/FR
 styralyl propionateFL/FR
ethereal
 ethyl isobutyrateFL/FR
fatty
2-dodecanoneFL/FR
2-dodecenalFL/FR
floral
 citronellyl acetateFL/FR
 geranyl tiglateFL/FR
fruity
isoamyl 2-methyl butyrateFL/FR
isobutyl 2-methyl butyrateFL/FR
3-heptyl dihydro-5-methyl-2(3H)-furanoneFL/FR
 neryl isovalerateFL/FR
 terpinyl formateFL/FR
green
(E)-2-heptenalFL
 phenyl acetaldehyde dimethyl acetalFL/FR
3-phenyl propionaldehydeFL/FR
waxy
alpha-hexyl cinnamaldehydeFL/FR
(E)-2-undecenalFL/FR
woody
(1S,5R)-myrtenyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 citrusFL
 fruit tropical fruit 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 allamanda cathartica linn. flower oil brazil @ 0.60%
Data  GC  Search Trop  Picture
 basil shoot oil
Search Trop  Picture
 bay laurel leaf
Search Trop  Picture
 calamus leaf oil @ 0.32%
Data  GC  Search Trop  Picture
 calamus rhizome oil @ 0.14%
Data  GC  Search Trop  Picture
 cananga leaf oil @ 0.7%
Data  GC  Search Trop  Picture
 carrot leaf oil @ 12.72%
Data  GC  Search Trop  Picture
 cascarilla bark oil @ 0.21%
Data  GC  Search Trop  Picture
 cedrela wood oil @ 3.20%
Data  GC  Search Trop  Picture
 chamomile garden chamomile plant
Search Trop  Picture
 citronella oil ceylon @ 3.77%
Data  GC  Search Trop  Picture
 citronella oil china @ 1.76%
Data  GC  Search Trop  Picture
 citronella oil java @ 2.25%
Data  GC  Search Trop  Picture
 clary sage oil greece @ 0.10%
Data  GC  Search Trop  Picture
 costmary oil @ 4.72%
Data  GC  Search Trop  Picture
 cubeb oil @ 4.39%
Data  GC  Search Trop  Picture
 curry wood leaf oil australia @ 0.20%
Data  GC  Search Trop  Picture
 eucalyptus globulus fruit oil @ trace%
Data  GC  Search Trop  Picture
 eucalyptus globulus oil pakistan @ 0.10%
Data  GC  Search Trop  Picture
 fleabane oil @ 0.10%
Data  GC  Search Trop  Picture
 grapefruit juice - 0.08 mg/kg
Search Trop  Picture
 grapefruit oil c.p. @ 0.04%
Data  GC  Search Trop  Picture
 grapefruit oil CO2 extract @ 0.36%
Data  GC  Search Trop  Picture
 guava fruit - up to 0.08 mg/kg
Search Trop  Picture
 hinoki leaf oil @ 0.48%
Data  GC  Search Trop  Picture
 horsemint shoot
Search Trop  Picture
 hyptis spicigera lam. oil mali @ trace-0.20%
Data  GC  Search Trop  Picture
 hyptis suaveolens (l.) poit. oil mali @ trace-0.20%
Data  GC  Search Trop  Picture
 labdanum oil @ 0.19%
Data  GC  Search Trop  Picture
 lavender oil spike spain @ 0.02%
Data  GC  Search Trop  Picture
 lemon balm shoot
Search Trop  Picture
 lemon verbena oil morocco @ 0.6%
Data  GC  Search Trop  Picture
 lime oil expressed florida @ trace%
Data  GC  Search Trop  Picture
 litsea cubeba oil china @ 0.24%
Data  GC  Search Trop  Picture
 lovage root oil @ 0.87%
Data  GC  Search Trop  Picture
 mace - trace amount
Search Trop  Picture
 mace oil @ trace%
Data  GC  Search  Picture
 mandarin oil italy @ trace%
Data  GC  Search  Picture
 mandarin oil uruguay @ 0.01%
Data  GC  Search Trop  Picture
 marsypianthes chamaedrys (vahl) kuntze oil brazil @ 0.50%
Data  GC  Search Trop  Picture
 michelia alba flower absolute @ 0.22%
Data  GC  Search Trop  Picture
 myristica fragrans fruit oil @ 0.10%
Data  GC  Search Trop  Picture
 nutmeg - trace amount
Search Trop  Picture
 nutmeg oil hydrodistilled india @ 0.1%
Data  GC  Search Trop  Picture
 orange fruit
Search Trop  Picture
 orange peel oil bitter china @ 0.36%
Data  GC  Search Trop  Picture
 orange peel oil bitter italy @ 0.05%
Data  GC  Search Trop  Picture
 oregano plant
Search Trop  Picture
 oregano shoot
Search Trop  Picture
 pepper black pepper fruit oil
Search Trop  Picture
 persea americana mill. fruit oil cuba @ 3.20%
Data  GC  Search Trop  Picture
 phlomis fruticosa l. flower oil greece @ 0.80%
Data  GC  Search Trop  Picture
 polyalthia australis (benth.) jessup leaf oil australia @ 0.30%
Data  GC  Search Trop  Picture
 prangos uloptera dc. oil iran @ 1.60%
Data  GC  Search Trop  Picture
 protium heptaphyllum (aubl.) march leaf oil brazil @ 0.80%
Data  GC  Search Trop  Picture
 ravintsara leaf oil @ 0.16%%
Data  GC  Search  Picture
 stachys recta l. oil serbia @ 0.10%
Data  GC  Search Trop  Picture
 sundacarpus amarus (blume) c.n. page leaf oil australia @ 0.10%
Data  GC  Search Trop  Picture
 water mint shoot
Search Trop  Picture
 wormwood flower oil annus america @ 0.94%
Data  GC  Search Trop  Picture
 wormwood leaf oil annus america @ 1.80-4.43%
Data  GC  Search Trop  Picture
 wormwood oil annus france @ 0.09-2.17%
Data  GC  Search Trop  Picture
 wormwood oil annus vietnam @ 5.59%
Data  GC  Search Trop  Picture
 yarrow oil greece @ 0.10%
Data  GC  Search Trop  Picture
 ylang ylang oil @ 0.58%
Data  GC  Search Trop  Picture
 ylang ylang oil CO2 extract @ 0.60%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
(-)-b-cubebene
(-)-beta-cubebene
1H-cyclopenta[1,3]cyclopropa[1,2]benzene, octahydro-7-methyl-3-methylene-4-(1-methylethyl)-, (4S,7R)-
10-methyl-4-methylene-7-isopropyl tricyclo(4.4.0.0(1.5))decane
(3aS-(3aalpha,3bbata, 4beta,7alpha,7aS*))-octahydro-7-methyl-3-methylene-4-(1-methyl ethyl)-1H-cyclopenta(1,3)cyclopropa(1,2)benzene
4-isopropyl-7-methyl-3-methylene-octahydro-cyclopenta[1,3]cyclopropa[1,2]benzene
rel-(4R,7S)-4-isopropyl-7-methyl-3-methyleneoctahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzene
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Chemical compositions and antimicrobial activity of the essential oils of Hornstedtia havilandii (Zingiberaceae).
PubMed: Chemical composition and major odor-active compounds of essential oil from PINELLIA TUBER (dried rhizome of Pinellia ternata) as crude drug.
PubMed: α-Iso-cubebene exerts neuroprotective effects in amyloid beta stimulated microglia activation.
PubMed: Study on the volatile oil contents of Annona glabra L., Annona squamosa L., Annona muricata L. and Annona reticulata L., from Vietnam.
PubMed: Constituents and antimicrobial activity of the essential oils from flower, leaf and stem of Helichrysum armenium.
PubMed: Chemical diversity of volatiles of Teucrium orientale L. var. orientale, var. puberulens, and var. glabrescens determined by simultaneous GC-FID and GC/MS techniques.
PubMed: Chemical composition and antioxidant activity of the essential oil of Tabernaemontana catharinensis A. DC. leaves.
PubMed: Chemical composition and mosquito larvicidal activities of Salvia essential oils.
PubMed: A chemical marker proposal for the Lantana genus: composition of the essential oils from the leaves of Lantana radula and L. canescens.
PubMed: Volatile compounds of flowers and leaves of Sideritis italica (Miller) Greuter et Burdet (Lamiaceae), a plant used as mountain tea.
PubMed: Essential oil composition from two species of Piperaceae family grown in Colombia.
PubMed: Chemical and genetic relationships among sage ( Salvia officinalis L.) cultivars and Judean sage ( Salvia judaica Boiss.).
PubMed: Essential oil compositions and cytotoxic activities of Dendropanax capillaris, Oreopanax nubigenus, and Schefflera rodrigueziana from Monteverde, Costa Rica.
PubMed: The main chemical composition and in vitro antifungal activity of the essential oils of Ocimum basilicum Linn. var. pilosum (Willd.) Benth.
PubMed: Biochemical and genomic characterization of terpene synthases in Magnolia grandiflora.
PubMed: [Gas chromatography for analysis of essential oils. Characteristics of essential oil of Dracocephalum species and the influence of extraction method on its composition].
PubMed: Platinum- and gold-catalyzed rearrangement reactions of propargyl acetates: total syntheses of (-)-alpha-cubebene, (-)-cubebol, sesquicarene and related terpenes.
PubMed: Phytochemical analysis and in vitro antimicrobial activity of two Satureja species essential oils.
PubMed: Volatile constituents of the flower and fruit oils of Pittosporum tobira (Thunb.) Ait. grown in Iran.
PubMed: Volatile oil composition of the aerial parts of Ajuga orientalis L. from Iran.
PubMed: Solid-phase microextraction of volatile compounds from the chopped leaves of three species of Eucalyptus.
PubMed: [Study of chemical constituents of essential oil from flowers of Mikania micrantha H.B.K].
PubMed: epi-Cubebanes from Solidago canadensis.
PubMed: Volatile Constituents of Montanoa tomentosa and Lippia graveolens.
PubMed: Constituents of peppers: IV. The hydrocarbons of pepper essential oil.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2017 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy