eucalyptus globulus oil pakistan
 
Notes:
Eucalyptus Globulus tree is planted practically all over the world in temperate and semitropical regions and in tropical highlands or swamps. The tree is found in France, Spain, Portugal, Algeria, North Africa, Brazil, Colombia, Ecuador and India. There are more eucalyptus trees in Brazil than in any other country outside of Australia. To a minor extent, it is planted in California and in numerous African and European countries. In the Belgian Congo, the Globulus tree has now been replaced with Eucalyptus Smithii. Eucalyptus Globulus oil is steam distilled from the fresh or partly dried, long and narrow leaves of this large beautiful tree. The oil is colorless and quite mobile when rectified. It is pale to dark yellow when old or poorly stored. The germicidal effect is not very outstanding. In perfumery, the oil enters numerous formulas for low cost perfumes, industrial perfumes, in the masking of various odors and as a replacement for other essential oils. It is comparatively stable in soap and it has a powerful radiation or lifting effect upon the other ingredients in the soap perfume. combination aerosol antiseptic containing eucalyptus oil. tsca definition 2008: extractives and their physically modified derivatives. eucalyptus, myrtaceae.
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Name: eucalyptus globulus leaf oil
CAS Number: 8000-48-4 
MDL: MFCD00146880
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2466  eucalyptus globulus oil pakistan
FDA Mainterm: EUCALYPTUS, OIL (EUCALYPTUS GLOBULUS LABILLE)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.90500 to 0.92500 @  25.00 °C.
Pounds per Gallon - (est).: 7.531 to  7.697
Refractive Index: 1.45800 to 1.46500 @  20.00 °C.
Boiling Point: 175.00 °C. @ 760.00 mm Hg
Congealing Point: 15.40 °C.
Flash Point: 112.00 °F. TCC ( 44.44 °C. )
Shelf Life: 24.00 month(s) or longer if stored properly.
Soluble in:
 alcohol
 water, 332.1 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
Odor Type: herbal
Odor Strength: medium
 herbal  eucalyptus  
Odor Description:
at 100.00 %. 
herbal eucalyptus
 eucalyptus  
Taste Description:
eucalyptus
Substantivity: 4 Hour(s)
  
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  2480 mg/kg
FCTXAV
13,107,1975

oral-child TDLo  2 mL/kg
BEHAVIORAL: ATAXIA
Medical Journal of Australia. Vol. 154, Pg. 430, 1991.

oral-child TDLo  218 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION SENSE ORGANS AND SPECIAL SENSES: CILIARY SPASM: EYE
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

oral-man LDLo  375 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): SWEATING: OTHER GASTROINTESTINAL: NAUSEA OR VOMITING
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.

oral-rat LD50  2480 mg/kg
Food and Cosmetics Toxicology. Vol. 13, Pg. 107, 1975.

Dermal Toxicity:
skin-rabbit LD50 2480 mg/kg
FCTOD7
26,323,1988

skin-rabbit LD50 2480 mg/kg
Food and Chemical Toxicology. Vol. 26, Pg. 323, 1988.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Critical Effect: Sensitization
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
citronellol Max. Found: <18.00 % and Reason: Sensitization
Recommendation for eucalyptus globulus oil pakistan usage levels up to:
  10.0000 % in the fragrance concentrate.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -76.00000
beverages(nonalcoholic): -1.70000
beverages(alcoholic): -1.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.5000050.00000
fruit ices: 0.5000050.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -130.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 8000-48-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 1993
 eucalyptus globulus leaf oil
Chemidplus: 0008000484
RTECS: LE2530000 for cas# 8000-48-4
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References:
 eucalyptus globulus leaf oil
Canada Domestic Sub. List: 8000-48-4
Pubchem (sid): 135264270
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 3301.29.6000
Household Products: Search
 Typical G.C.
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: EUCALYPTUS OIL
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 eucalyptus globulus
Search Trop  Picture
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Synonyms:
 eucalyptus globulus oil pakistan
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Articles:
PubMed: Anti-inflammatory Properties of the Monoterpene 1.8-cineole: Current Evidence for Co-medication in Inflammatory Airway Diseases.
PubMed: Antibacterial activity of the essential oils from the leaves of Eucalyptus globulus against Escherichia coli and Staphylococcus aureus.
PubMed: Chemical variation in a dominant tree species: population divergence, selection and genetic stability across environments.
PubMed: Compositional analysis and insecticidal activity of Eucalyptus globulus (family: Myrtaceae) essential oil against housefly (Musca domestica).
PubMed: Stability of plant defensive traits among populations in two Eucalyptus species under elevated carbon dioxide.
PubMed: Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus.
PubMed: Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds.
PubMed: Chemical composition and antimicrobial activity of essential oils of Thymus algeriensis, Eucalyptus globulus and Rosmarinus officinalis from Morocco.
PubMed: Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens.
PubMed: GC/MS analysis and antimicrobial activity of the essential oil of fresh leaves of Eucalytus globulus, and leaves and stems of Smyrnium olusatrum from Constantine (Algeria).
PubMed: Liquid and vapour-phase antifungal activities of selected essential oils against Candida albicans: microscopic observations and chemical characterization of Cymbopogon citratus.
PubMed: Encapsulation of essential oils within a polymeric liposomal formulation for enhancement of antimicrobial efficacy.
PubMed: Antimicrobial action of essential oil vapours and negative air ions against Pseudomonas fluorescens.
PubMed: Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens.
PubMed: Efficacy of spray formulations containing binary mixtures of clove and eucalyptus oils against susceptible and pyrethroid/ malathion-resistant head lice (Anoplura: Pediculidae).
PubMed: Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil.
PubMed: Genotoxic activity of Eucalyptus globulus essential oil in Aspergillus nidulans diploid cells.
PubMed: Eucalyptus essential oil toxicity against permethrin-resistant Pediculus humanus capitis (Phthiraptera: Pediculidae).
PubMed: [Ovicidal and larvicidal activity in vitro of Eucalyptus globulus essential oils on Haemonchus contortus].
PubMed: Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA).
PubMed: Fungitoxicity of some higher plants and synergistic activity of their essential oils against Sclerotium rolfsii sacc. causing foot-rot disease of barley.
PubMed: Effects of direct exposure of green odour components on dopamine release from rat brain striatal slices and PC12 cells.
PubMed: Effect of eucalyptus essential oil on respiratory bacteria and viruses.
PubMed: A TLC bioautographic assay for the detection of nitrofurantoin resistance reversal compound.
PubMed: [The expression of TLR4 in rat acute lung injury induced by lipopolysaccharide and the influence of Eucalyptus globulus oil].
PubMed: The insecticidal activity of Eucalyptus globulus oil on the development of Musca domestica third stage larvae.
PubMed: Fumigant activity of plant essential oils and components from garlic (Allium sativum) and clove bud (Eugenia caryophyllata) oils against the Japanese termite (Reticulitermes speratus Kolbe).
PubMed: Laboratory evaluation of Melia azedarach L. and Eucalyptus globulus Labill. Extracts in order to control Ocneridia volxemi Bolivar (Orthoptera, Pamphaginae) hoppers.
PubMed: [Effect of Eucalyptus globulus oil on lipopolysaccharide-induced chronic bronchitis and mucin hypersecretion in rats].
PubMed: [Determination of chemical constituents of essential oil from the fruit of Eucalyptus globulus by GC-MS].
PubMed: Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction.
PubMed: Monoterpenes and epicuticular waxes help female autumn gum moth differentiate between waxy and glossy Eucalyptus and leaves of different ages.
PubMed: Ovicidal and adulticidal activity of Eucalyptus globulus leaf oil terpenoids against Pediculus humanus capitis (Anoplura: Pediculidae).
PubMed: Analgesic and anti-inflammatory effects of essential oils of Eucalyptus.
PubMed: [Effect of eucalyptus globulus oil on activation of nuclear factor-kappaB in THP-1 cells].
PubMed: Roles of human CYP2A6 and 2B6 and rat CYP2C11 and 2B1 in the 10-hydroxylation of (-)-verbenone by liver microsomes.
PubMed: Eucalyptus globulus (camphor oil) against the zoonotic scabies, Sarcoptes scabiei.
PubMed: Eucalyptus globulus (camphor oil) in the treatment of human demodicidosis.
PubMed: Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo.
PubMed: Antioxidant activity of extracts from plants growing in Sardinia.
PubMed: Cross-resistance of a chlorpyrifos-methyl resistant strain of Oryzaephilus surinamensis (Coleoptera: Cucujidae) to fumigant toxicity of essential oil extracted from Eucalyptus globulus and its major monoterpene, 1,8-cineole.
PubMed: Analysis of medicinal oil from Eucalyptus globulus. ssp. bicostata leaves.
PubMed: Comparison of rumen microbial inhibition resulting from various essential oils isolated from relatively unpalatable plant species.
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