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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | pale yellow to yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 155.86 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 2.970000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 143.00 °F. TCC ( 61.70 °C. ) (est)
|
| logP (o/w): | 1.381 (est) |
| Soluble in: |
| | alcohol | | | water, 8135 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Type: green |
Odor Strength:high ,
recommend smelling in a 1.00 % solution or less |
| Substantivity: > 1 hour(s) at 100.00 % |
| fatty sweet green aldehydic spicy |
| Odor Description:at 1.00 % in dipropylene glycol. fatty sweet green aldehydic spicy |
| Flavor Type: green |
| green creamy |
| Taste Description: green creamy |
| Odor and/or flavor descriptions from others (if found). |
| Bedoukian Research |
| 2,4-HEXADIEN-1-AL |
Odor Description:Fatty, sweet, green aldehydic odor with a spicy finish
This material should NOT be used as a fragrance ingredient due to the absence of data necessary to perform an adequate safety evaluation per IFRA Safety Standards in Annex 1 of the Code of Practice. |
Taste Description:Sweet, green, creamy
Citrus flavors, especially orange and tangerine. Can also be used for spicy notes in graham crackers. |
Cosmetic Information:
Suppliers:
| Bedoukian Research |
| 2,4-HEXADIEN-1-AL
Odor: Fatty, sweet, green aldehydic odor with a spicy finish Use: This material should NOT be used as a fragrance ingredient due to the absence of data necessary to perform an adequate safety evaluation per IFRA Safety Standards in Annex 1 of the Code of Practice. Flavor: Sweet, green, creamy Citrus flavors, especially orange and tangerine. Can also be used for spicy notes in graham crackers. |
| CJ Latta & Associates |
| 2,4-HEXADIENAL
|
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | flavoring agents |
| IFRA Critical Effect: | | Insufficient data |
| | View the IFRA Standard |
| Recommendation for 2,4-hexadienal usage levels up to: | | | PROHIBITED: Should not be used as a fragrance ingredient.
|
| |
Safety References:
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| aldehydic |
octanal (aldehyde C-8)
FL/FR |
2- tridecenal
FL/FR |
| balsamic |
guaiyl acetate
FL/FR |
| citrus |
citral
FL/FR |
2- tetradecenal
FL/FR |
tetrahydrocitral
FL/FR |
| fatty |
3- decen-2-one
FL/FR |
(E,Z)-2,6- dodecadienal
FL/FR |
methyl 2-hexenoate
FL/FR |
6- methyl-5-hepten-2-one propylene glycol acetal
FL/FR |
(E)-2- nonenal
FL/FR |
2- nonenal
FL/FR |
2- octenal
FL/FR |
| floral |
ocean propanal
FL/FR |
clementine petitgrain oil
FL/FR |
| fruity |
iso amyl octanoate
FL/FR |
methyl 2-methyl butyrate
FL/FR |
methyl 3-nonenoate
FL/FR |
octen-1-yl cyclopentanone
FL/FR |
octyl butyrate
FL/FR |
(E)-2- undecenal
FL/FR |
| green |
cilantro leaf oil
FL/FR |
iso cyclocitral (IFF)
FL/FR |
heptanal (aldehyde C-7)
FL/FR |
(Z)-4- heptenal
FL/FR |
2- heptyl furan
FL/FR |
hexanal (aldehyde C-6)
FL/FR |
(Z)-3- hexenal
FL/FR |
3,5- ivy carbaldehyde
FL/FR |
ivy carbaldehyde
FL/FR |
2,4- ivy carbaldehyde
FL/FR |
(E,Z)-3,6- nonadien-1-ol
FL/FR |
(E)-2- nonen-1-ol
FL/FR |
(Z)-2- nonen-1-ol
FL/FR |
(E)-2- octen-1-yl acetate
FL/FR |
olive oil absolute
FL/FR |
| herbal |
3- octyl acetate
FL/FR |
| spicy |
cumin seed absolute
FL/FR |
| waxy |
allyl nonanoate
FL/FR |
decanal diethyl acetal
FL/FR |
9- decenoic acid
FL/FR |
heptyl octanoate
FL/FR |
2,4- nonadien-1-ol
FL/FR |
propyl decanoate
FL/FR |
| For Flavor |
| No flavor group found for these |
9- decen-2-one
FL |
2- decyl furan
FL |
epoxy-2-decenal
FL |
furfuryl hexanoate
FL |
guaiyl acetate
FL/FR |
(E,E)-2,4- heptadien-1-ol
FL |
hexanal butane-2,3-diol acetal
FL |
hexyl (E)-2-hexenoate
FL |
ivy carbaldehyde
FL/FR |
3,5- ivy carbaldehyde
FL/FR |
methyl 2-hexenoate
FL/FR |
6- methyl octanal
FL |
6- methyl-5-hepten-2-one propylene glycol acetal
FL/FR |
2- octenal
FL/FR |
propyl decanoate
FL/FR |
2- propyl pyridine
FL |
2- tetradecenal
FL/FR |
tetrahydrocitral
FL/FR |
|
(±)-3-( methyl thio) heptanal
FL |
| aldehydic |
| aldehydic |
octanal (aldehyde C-8)
FL/FR |
2- tridecenal
FL/FR |
| citrus |
cilantro leaf oil
FL/FR |
citral
FL/FR |
clementine petitgrain oil
FL/FR |
| fatty |
2,4- decadienal
FL |
(E,E)-2,4- heptadienal
FL |
2- heptyl furan
FL/FR |
2,4- nonadien-1-ol
FL/FR |
2,4- nonadienal
FL |
(Z)-2- nonen-1-ol
FL/FR |
2- nonenal
FL/FR |
| floral |
ocean propanal
FL/FR |
| fruity |
iso amyl octanoate
FL/FR |
methyl (E)-3-nonenoate
FL |
methyl 2-methyl butyrate
FL/FR |
methyl 3-nonenoate
FL/FR |
octen-1-yl cyclopentanone
FL/FR |
| green |
avocado flavor
FL |
iso cyclocitral (IFF)
FL/FR |
3- decen-2-one
FL/FR |
dihydroxyacetophenone (mixed isomers)
FL |
(E,Z)-2,6- dodecadienal
FL/FR |
heptanal (aldehyde C-7)
FL/FR |
(Z)-4- heptenal
FL/FR |
(E)-2- heptenal
FL |
hexanal (aldehyde C-6)
FL/FR |
(Z)-3- hexenal
FL/FR |
2- hexyl pyridine
FL |
2,4- ivy carbaldehyde
FL/FR |
(E,Z)-3,6- nonadien-1-ol
FL/FR |
(E)-2- nonen-1-ol
FL/FR |
(E)-2- nonenal
FL/FR |
2,4- octadienal
FL |
(E,E)-2,4- octadienal
FL |
(E)-2- octen-1-yl acetate
FL/FR |
3- octyl acetate
FL/FR |
| oily |
olive oil absolute
FL/FR |
| pungent |
acetaldehyde
FL |
| spicy |
cumin seed absolute
FL/FR |
| waxy |
allyl nonanoate
FL/FR |
decanal diethyl acetal
FL/FR |
9- decenoic acid
FL/FR |
heptyl octanoate
FL/FR |
octyl butyrate
FL/FR |
(E)-2- undecenal
FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | hexa-2,4-dienal | | 2,4- | hexadien-1-al |
Articles:
| PubMed:Comprehensive analysis of the catalytic and structural properties of a mu-class glutathione s-transferase from Fasciola gigantica. |
| PubMed:Degradation of Diphenyl Ether in Sphingobium phenoxybenzoativorans SC_3 Is Initiated by a Novel Ring Cleavage Dioxygenase. |
| PubMed:Multi-trait analysis of post-harvest storage in rocket salad (Diplotaxis tenuifolia) links sensorial, volatile and nutritional data. |
| PubMed:PARTICIPATION OF Y89 AND Y97 IN THE CONJUGATING ACTIVITY OF Drosophila melanogaster GLUTATHIONE S-TRANSFERASE D3 (DmGSTD3). |
| PubMed:Use of TD-GC-TOF-MS to assess volatile composition during post-harvest storage in seven accessions of rocket salad (Eruca sativa). |
| PubMed:Change of volatile compounds in fresh fish meat during ice storage. |
| PubMed:exo-Selective asymmetric Diels-Alder reaction of 2,4-dienals and nitroalkenes by trienamine catalysis. |
| PubMed:Laboratory investigation on the role of organics in atmospheric nanoparticle growth. |
| PubMed:Volatile composition of four southern highbush blueberry cultivars and effect of growing location and harvest date. |
| PubMed:Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds. |
| PubMed:Synthesis and biological evaluation of (+/-)-dinemasone C and analogues. |
| PubMed:The fate of benzene-oxide. |
| PubMed:Aldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived alpha, beta-unsaturated carbonyls at physiological levels. |
| PubMed:Effect of soybean volatile compounds on Aspergillus flavus growth and aflatoxin production. |
| PubMed:A kinetic and mechanistic study of the amino acid catalyzed aldol condensation of acetaldehyde in aqueous and salt solutions. |
| PubMed:Characterization of Taenia solium cysticerci microsomal glutathione S-transferase activity. |
| PubMed:The atmospheric photolysis of E-2-hexenal, Z-3-hexenal and E,E-2,4-hexadienal. |
| PubMed:Volatile emissions from Aesculus hippocastanum induced by mining of larval stages of Cameraria ohridella influence oviposition by conspecific females. |
| PubMed:Metabolism of trans, trans-muconaldehyde, a cytotoxic metabolite of benzene, in mouse liver by alcohol dehydrogenase Adh1 and aldehyde reductase AKR1A4. |
| PubMed:Syntheses of (-)-TAN-2483A, (-)-massarilactone B, and the fusidilactone B ring system. Revision of the structures of and syntheses of (+/-)-Waol A (FD-211) and (+/-)-Waol B (FD-212). |
| PubMed:Purification, characterization and kinetic properties of the Taenia solium glutathione S-transferase isoform 26.5 kDa. |
| PubMed:NTP toxicology and carcinogensis Studies of 2,4-hexadienal (89% trans,trans isomer, CAS No. 142-83-6; 11% cis,trans isomer) (Gavage Studies). |
| PubMed:Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities. |
| PubMed:Particle growth by acid-catalyzed heterogeneous reactions of organic carbonyls on preexisting aerosols. |
| PubMed:Alpha,beta-unsaturated carbonyl compounds: induction of oxidative DNA damage in mammalian cells. |
| PubMed:Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice. |
| PubMed:Synthesis of (-)-TAN-2483A. Revision of the structures and syntheses of (+/-)-FD-211 (waol A) and (+/-)-FD-212 (waol B). |
| PubMed:Short term feeding of hexadienal to postnatal rats: effects on stomach aldehyde dehydrogenase. |
| PubMed:Thresholds of carcinogenicity of flavors. |
| PubMed:Identification of aroma compounds in Parmigiano-Reggiano cheese by gas chromatography/olfactometry. |
| PubMed:The influence of the solvents DMSO and ethanol on the genotoxicity of alpha,beta-unsaturated aldehydes in the SOS chromotest. |
| PubMed:Glutathione S-transferase pi expression in forestomach carcinogenesis process induced by gavage-administered 2,4-hexadienal in the F344 rat. |
| PubMed:DNA-damaging potential and glutathione depletion of 2-cyclohexene-1-one in mammalian cells, compared to food relevant 2-alkenals. |
| PubMed:Structure-activity relationships in the induction of DNA-protein cross-links by hematotoxic ring-opened benzene metabolites and related compounds in HL60 cells. |
| PubMed:Appearance of cross linked proteins in human atheroma and rat pre-fibrotic liver detected by a new monoclonal antibody. |
| PubMed:Reactive ring-opened aldehyde metabolites in benzene hematotoxicity. |
| PubMed:Neighboring Group Effects in Intramolecular Aldol Condensations. Rate Enhancement by gamma Substituents(1). |
| PubMed:Chemistry and antimicrobial activity of caryoynencins analogs. |
| PubMed:Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite. |
| PubMed:The hematotoxic effects of 6-hydroxy-trans,trans-2,4-hexadienal, a reactive metabolite of trans,trans-muconaldehyde, in CD-1 mice. |
| PubMed:Interaction of trans,trans-muconaldehyde with bovine serum albumin. |
| PubMed:Mutagenicity of trans,trans-muconaldehyde and its metabolites in V79 cells. |
| PubMed:Reaction of (E,E)-muconaldehyde and its aldehydic metabolites, (E,E)-6-oxohexadienoic acid and (E,E)-6-hydroxyhexa-2,4-dienal, with glutathione. |
| PubMed:Identification and characterization of deoxyguanosine adducts of mutagenic beta-alkyl-substituted acrolein congeners. |
| PubMed:Pathways of trans,trans-muconaldehyde metabolism in mouse liver cytosol: reversibility of monoreductive metabolism and formation of end products. |
| PubMed:Cell spreading on collagen that has been exposed to reactive aldehydes. |
| PubMed:Mutagenicity of beta-alkyl substituted acrolein congeners in the Salmonella typhimurium strain TA100 and genotoxicity testing in the SOS chromotest. |
| PubMed:Pseudo malonaldehyde activity in the thiobarbituric acid test. |
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3D/inchi