• Advanced Biotech
  • Berjé
    • Berjé Inc.
      The solution is clear
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
      Email:For Information
      Email:For Sales
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      US Voice:845-341-2100
      US Fax:845-341-2121
      sclareol natural
  • H. Interdonati, Inc.
    • H. Interdonati, Inc.
      Innovative products
      Because your flavors and fragrances are only as good as their source "Since 1952"
      H. Interdonati, Inc. began in 1952 with the tradition of delivering quality pharmaceuticals and fine chemical ingredients at competitive prices. The mission was simple: To provide the most reliable, personal service in the industry.
      US Email:Info
      US Email:Andrew Interdonati (Sales)
      Voice:800 367-6617
      Fax:631 367-6626
      Sclareol Natural, Kosher
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. We warmly welcome your inquiries, come witness our solemn commitment for yourself.
      US Email:Sales
      Voice:+86-21-32515501 60762991 60762992
      Fax:+86-21-32515502 64204960
      US Voice:908-359-9000
      US Fax:908-359-9002
      SCLAREOL, Kosher
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email:Technical Services
      US Email:Sales
      US Voice:(973) 740-2300
      US Fax:(973) 740-1839
      SCLAREOL, Kosher
  • Home
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  • Organoleptics
      • Organoleptic Properties
        Odor Type :balsamic
        Odor Strength :low
        Odor Description:
        at 100.00 %. 
        sweet balsam clary amber woody weedy
        Luebke, William tgsc, (1988)
        Odor sample from :RJR Technical Company
        Substantivity :292 Hour(s)
  • Properties
      • Physical Properties
        Appearance :amber solid (est)
        Assay : 98.00 to 100.00 % sum of isomers
        Food Chemicals Codex Listed :No
        Melting Point : 105.00 to  107.00 °C. @ 760.00 mm Hg
        Boiling Point : 218.00 to  220.00 °C. @ 19.00 mm Hg
        Flash Point : 336.00 °F. TCC ( 169.10 °C. ) (est)
        logP (o/w) : 5.233 (est)
  • Safety
      • Safety Information
        Most important hazard(s) :None - None found.
          S 02 - Keep out of the reach of children.
        S 24/25 - Avoid contact with skin and eyes.
        Oral/Parenteral Toxicity : 
          oral-rat LD50  > 5000 mg/kg
        Food and Chemical Toxicology. Vol. 30, Pg. 115S, 1992.

        Dermal Toxicity : 
          skin-rabbit LD50 > 5000 mg/kg
        Food and Chemical Toxicology. Vol. 30, Pg. 115S, 1992.

        Inhalation Toxicity : 
          Not determined
  • Safety in Use
      • Safety in Use Information
        Category :flavor and fragrance agents
        Maximised Survey-derived Daily Intakes (MSDI-EU) :0.67 (μg/capita/day)
        Modified Theoretical Added Maximum Daily Intake (mTAMDI) :3900 (μg/person/day)
        Threshold of Concern :1800 (μg/person/day)
        Structure Class :I
        IFRA Critical Effect :Sensitization
        IFRA Purity Specification :98% minimum purity
        IFRA fragrance material specification :
         Sclareol used as a fragrance ingredient should have a minimum purity of 98%.
        IFRA :View Standard
        maximum skin levels for fine fragrances :
          0.0200 %  and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). (IFRA, 2004)
        Recommendation for sclareol fragrance usage levels up to :
          4.0000 % in the fragrance concentrate.
        use level in formulae for use in cosmetics :
          0.0300 %
        Dermal Systemic Exposure in Cosmetic Products :
         0.0008 mg/kg/day (IFRA, 2004)
        Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
        The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA on the "Resources" link.
        publication number : 24
         average usual ppmaverage maximum ppm
        baked goods : 10.0000050.00000
        beverages(nonalcoholic) : 5.0000025.00000
        beverages(alcoholic) : 5.0000025.00000
        breakfast cereal : 5.0000025.00000
        cheese : 7.0000035.00000
        chewing gum : --
        condiments / relishes : 20.00000100.00000
        confectionery froastings : 10.0000050.00000
        egg products : --
        fats / oils : 5.0000025.00000
        fish products : 2.0000010.00000
        frozen dairy : 7.0000035.00000
        fruit ices : 10.0000050.00000
        gelatins / puddings : 10.0000050.00000
        granulated sugar : --
        gravies : 5.0000025.00000
        hard candy : 10.0000050.00000
        imitation dairy : 7.0000035.00000
        instant coffee / tea : 5.0000025.00000
        jams / jellies : 7.0000035.00000
        meat products : 2.0000010.00000
        milk products : 7.0000035.00000
        nut products : 5.0000025.00000
        other grains : 5.0000025.00000
        poultry : 2.0000010.00000
        processed fruits : 7.0000035.00000
        processed vegetables : 7.0000035.00000
        reconstituted vegetables : 7.0000035.00000
        seasonings / flavors : 5.0000025.00000
        snack foods : 10.0000050.00000
        soft candy : 10.0000050.00000
        soups : 5.0000025.00000
        sugar substitutes : --
        sweet sauces : 5.0000025.00000
        Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
        Note : mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
         average usage mg/kgmaximum usage mg/kg
        Dairy products, excluding products of category 02.0 (01.0) : 7.0000035.00000
        Fats and oils, and fat emulsions (type water-in-oil) (02.0) : 5.0000025.00000
        Edible ices, including sherbet and sorbet (03.0) : 10.0000050.00000
        Processed fruit (04.1) : 7.0000035.00000
        Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) : --
        Confectionery (05.0) : 10.0000050.00000
        Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) : 5.0000025.00000
        Bakery wares (07.0) : 10.0000050.00000
        Meat and meat products, including poultry and game (08.0) : 2.0000010.00000
        Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) : 2.0000010.00000
        Eggs and egg products (10.0) : --
        Sweeteners, including honey (11.0) : --
        Salts, spices, soups, sauces, salads, protein products, etc. (12.0) : 5.0000025.00000
        Foodstuffs intended for particular nutritional uses (13.0) : 10.0000050.00000
        Non-alcoholic ("soft") beverages, excl. dairy products (14.1) : 5.0000025.00000
        Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) : 10.0000050.00000
        Ready-to-eat savouries (15.0) : 20.00000100.00000
        Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) : 5.0000025.00000
  • Safety References
(1R,2R,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-enyl]-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol (Click)
CAS Number : 515-03-7 17904-64-2
ESIS EC# (EINECS) :208-194-0
Beilstein Number :2054148
MDL :MFCD00869558
CoE Number :10311
XlogP3-AA :4.90 (est)
Molecular Weight :308.50532000
Formula :C20 H36 O2
NMR Predictor :Predict
(1R,2R,4aS,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-enyl]-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol (Click)
CAS Number : 515-03-7  (RRS)
XlogP3-AA :4.90 (est)
Molecular Weight :308.50532000
Formula :C20 H36 O2
BioActivity Summary :listing
NMR Predictor :Predict
Category :flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
Google Scholar : Search Google Books : Search
Google Scholar : with word "volatile"Search Google Scholar : with word "flavor"Search
Google Scholar : with word "odor"SearchPerfumer and Flavorist : Search
Google Patents : Search US Patents : Search
EU Patents : Search
Pubchem Patents:Search
PubMed : SearchNCBI : Search
JECFA Food Flavoring :2029  (-)-sclareol
Flavis Number :02.206 (Old site)
EU SANCO Food Flavourings :02.206  (-)-sclareol

FEMA Number :4502  (-)-sclareol
FDA Mainterm : (-)-SCLAREOL
click on the picture(s) below to
interact with the 3D model
Picture of molecule
Picture of molecule
Synonyms :
alpha-ethenyl decahydro-2-hydroxy-a,2,5,5,8a-pentamethyl(1R-(1alpha(R*),2beta,4abeta,8H
(1theta- (1alpha (theta),2beta, 4abeta,8aalpha))-alpha-ethenyl decahydro-2-hydroxy-alpha,2,5,5,8a-pentamethyl-1-naphthalene propanol
(1R-(1alpha(R*), 2beta,4abeta, 8aalpha))-2-hydroxy-alpha,2,5,5,8a-pentamethyl-alpha-vinyl decahydronaphthalene-1-propan-1-ol
 labd-14-ene-8,13-diol, (13R)-
1-naphthalenepropanol, a-ethenyldecahydro-2-hydroxy-a,2,5,5,8a-pentamethyl-, (aR,1R,2R,4aS,8aS)-
 sclareol natural
Soluble in :
 water, 0.08174 mg/L @ 25 °C (est)
Insoluble in :
Stability :
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