glycyrrhiza glabra root extract
extract of the roots of the licorice, glycyrrhiza glabra l., leguminosae
 
Notes:
Licorice or, more correctly, Licorice Extract is produced from the rhizomes and roots of Glycyrrhiza Glabra, a leguminous plant. There are two main varieties of this plant: the Typica which is known commercially as Spanish licorice and the Glandulifera which is generally called Russian licorice. The former comes from Spain and Italy, the latter from Turkey, U.S.S.R. and the countries around Asia Minor towards India. By extraction of the comminuted rhizomes and roots with boiling water, followed by evaporation of the aqueous extract, the well known solid Licorice Extract is prepared. Licorice Extract is black and brittle and has a sweet, mild odor somewhat different from that of the botanical starting material. Licorice extract has a very sweet taste and a rich, root like, slightly spicy caramellic body of flavor. It leaves a faintly scratching feeling in the back of the mouth and it is used in medicine for its mildly expectorant effect. Used for blemished skin preparations by containing glycyrrhizin, a saponin that has anti-inflammatory properties.
  • Advanced Biotech
  • Frutarom
    • Frutarom Ltd
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      At Frutarom, we take pride in our expertise and knowledge of Flavour & Fragrance Ingredients and our thorough understanding of the needs of Flavourists, Perfumers and Food Technologists. Working closely with our customers we have a strong track record of providing unique solutions to fulfil requirements.
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      Product(s):
      103244 Licorice Root Extract
       
  • Horner International
    • Horner International
      The finest extracts in the world
      Horner International supplies the finest natural extracts and flavors to a world-wide customer base.
      Horner International supplies the finest natural extracts and flavors to a world-wide customer base. Our new North American production facility in Durham, North Carolina features multiple production lines for extraction and concentration via proprietary technology. A diverse team with decades of experience and know-how, we apply our skills to some of the most challenging products found in nature. We are committed to treat our customers in the way we wish to be treated. We believe that natural products play a positive, sustainable role in a future that is good for farmers, communities, and our customers. Our goal is to produce the best-tasting, most consistent natural extracts and flavors in the world.
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      US Voice: +1 919 787 3112 ext. 112
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      Custom Manufacturing
      Product(s):
      Licorice Extract
       
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
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      Product(s):
      LICORICE ROOT EXTRACT HS 2511 G
      LICORICE ROOT EXTRACT LS 3304 G
       
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Name: glycyrrhiza glabra root extract
CAS Number: 84775-66-6 
ECHA EC Number: 283-895-2
FDA UNII: 2788Z9758H
Category: cosmetic, flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
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PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1408 Glycyrrhiza View-review
184.1408 Licorice, Glycyrrhiza, and Ammoniated Glycyrrhizin View-review
FEMA Number: 2628  licorice root extract
FDA Mainterm: LICORICE EXTRACT (GLYCYRRHIZA SPP.)
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1408 Licorice and licorice derivatives.
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Physical Properties:
Appearance: black liquid to solid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.99130 to 1.06130 @  25.00 °C.
Pounds per Gallon - (est).: 8.249 to  8.831
Refractive Index: 1.34000 to 1.39000 @  20.00 °C.
Shelf Life: 6.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
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Organoleptic Properties:
Odor Type: licorice
Odor Strength: medium
 sweet  licorice  
Odor Description:
at 100.00 %. 
sweet licorice root
 licorice  
Taste Description:
licorice
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: bleaching agents
emollients
perfuming agents
skin conditioning
smoothing agents
soothing agents
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Suppliers:
Advanced Biotech
LICORICE ROOT EXTRACT ORGANIC
Amax Nutrasource
Licorice Root Extract, 20% Glycyrrhizic Acid
Aromaplant
Licorice Root Extract
Flavor: characteristic
The source material of licorice extract, licorice root (Glycyrrhiza Glabra), grows in various countries, including China, Turkey, Russia and Italy. The chemical specifications, flavour and aroma of this voluntary plant are affected by climatic conditions.
Bell Flavors & Fragrances
Licorice Extract Natural
Bio-Botanica®
Licorice Root Glycyrrhiza Glabra (Licorice) Root Extract
Bio-Botanica®
Licorice Root, AF – 5498
Bio-Botanica®
Licorice Root, FE – 5083
Carrubba
licorice extract
Changsha Organic Herb
Licorice Root Extract
Chemical-navi - Nikkol
AQUA LICORICE EXTRACT P-T
Odor: characteristic
Use: Extract from licorice root with Glabridin content 1.50 - 2.50 % enhancing better whitening effect. Freely soluble in water.
Chemical-navi - Nikkol
POLYOL SOLUBLE LICORICE EXTRACT HG
Odor: characteristic
Use: Extract from licorice root with strong anti-pigmentation effect.
Chemical-navi - Nikkol
POLYOL SOLUBLE LICORICE EXTRACT P-T(40)
Odor: characteristic
Use: Licorice derivative with 40% glabridin content. Strong anti-pigmentation effect.
Frutarom
Licorice Root Extract
Flavor: Sweet, Herbal, Roasted, Tea-like
Grau Aromatics
LICORICE ROOT EXTRACT HS 2511 G
(hydrosoluble)
Grau Aromatics
LICORICE ROOT EXTRACT LS 3304 G
(liposoluble)
Haldin International
Licorice
Horner International
Licorice Extract
Indo World Trading
Glycyrrhiza Glabra (mulethi) Extract
Lipotec USA
Actiphyte® of Licorice Root Extract
Sabinsa Corporation
Glycyrrhizinic Acid
Sabinsa Corporation
Licorice Extract CG
Shank's Extracts
Licorice Root Extract, Natural
SRS Aromatics
LICORICE ROOT EXTRACT HS 2511 G
SRS Aromatics
LICORICE ROOT EXTRACT LS 3304 G
Vege Tech
licorice extract
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  14200 mg/kg

intraperitoneal-rat LD50  1420 mg/kg

oral-mouse LD50  > 7500 mg/kg

intraperitoneal-mouse LD50  1500 mg/kg

Dermal Toxicity:
subcutaneous-rat LD50 4200 mg/kg

subcutaneous-mouse LD50 4000 mg/kg

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic, flavor and fragrance agents
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -84.00000
beverages(nonalcoholic): -33.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -29000.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -39.00000
fruit ices: -39.00000
gelatins / puddings: -4.00000
granulated sugar: --
gravies: --
hard candy: -130.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 glycyrrhiza glabra root extract
Chemidplus: 0084775666
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References:
 glycyrrhiza glabra root extract
Pubchem (sid): 135314337
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 1302.12.0000
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 emollients 
 licoriceFL
 skin conditioning 
 smoothing agents 
 soothing agents 
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Occurrence (nature, food, other): note
 licorice
Search Trop  Picture
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Synonyms:
 aqua licorice extract P-T
 extract of the roots of the licorice, glycyrrhiza glabra l., leguminosae
 glycyrrhiza glabra (mulethi) extract
 licorice root extract
actiphyte of licorice root extract
 licorice root extract natural
 licorice root extract, 20% glycyrrhizic acid
 polyol soluble licorice extract HG
 polyol soluble licorice extract P-T(40)
 vedaplex 146
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Articles:
PubMed: Evaluation of sodium benzoate and licorice (Glycyrrhiza glabra) root extract as heat-sensitizing additives against Escherichia coli O157:H7 in mildly heated young coconut liquid endosperm.
PubMed: Enhancement of Hippocampal CA3 Neuronal Dendritic Arborization by Glycyrrhiza glabra root extract Treatment in Wistar Albino Rats.
PubMed: Beneficial effect of aqueous root extract of Glycyrrhiza glabra on learning and memory using different behavioral models: An experimental study.
PubMed: Improving the thrombin inhibitory activity of glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety.
PubMed: Effect of GutGard in the Management of Helicobacter pylori: A Randomized Double Blind Placebo Controlled Study.
PubMed: Anti-convulsant action and amelioration of oxidative stress by Glycyrrhiza glabra root extract in pentylenetetrazole- induced seizure in albino rats.
PubMed: Chromolithic method development, validation and system suitability analysis of ultra-sound assisted extraction of glycyrrhizic acid and glycyrrhetinic acid from Glycyrrhiza glabra.
PubMed: 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice.
PubMed: Protection of DNA and microsomal membranes in vitro by Glycyrrhiza glabra L. against gamma irradiation.
PubMed: Immunological studies of Revitonil, a phytopharmaceutical containing Echinacea purpurea and Glycyrrhiza glabra root extract.
PubMed: Inhibition of human complement by beta-glycyrrhetinic acid.
PubMed: Transdermal microemulsions of Glycyrrhiza glabra L.: characterization, stability and evaluation of antioxidant potential.
PubMed: Evaluation of the genotoxic potential of standardized extract of Glycyrrhiza glabra (GutGard™).
PubMed: Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6.
PubMed: Memory enhancing activity of Glycyrrhiza glabra in mice.
PubMed: Screening of traditionally used South African plants for antifungal activity against Candida albicans.
PubMed: [Differences between the root and rhizome of Ural licorice (Glycyrrhiza uralensis Fisch.) and those of smooth licorice (Glycyrrhiza glabra L.)].
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