verbena absolute france
aloysia triphylla absolute france
 
Notes:
Do not use on any part of the body because of sensitizing potential.tsca definition 2008: extractives and their physically modified derivatives. aloysia triphylla, verbenaceae.
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Name: lippia citriodora absolute
CAS Number: 8024-12-2 
Name: aloysia citriodora extract
CAS Number: 85116-63-8 
ECHA EC Number: 285-215-0
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm: LEMON VERBENA, OIL (LIPPIA CITRIODORA)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
 water, 84.71 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
Odor Type: citrus
Odor Strength: medium
 green  tea  hay  herbal  sweet  citrus  
Odor Description:
at 100.00 %. 
green tea hay herbal sweet citrus
 green  tea  hay  herbal  sweet  citrus  
Odor Description:
Green, tea-like, hay, herbal with a sweet citrus nuance
Mosciano, Gerard P&F 17, No. 6, 41, (1992)
 sweet  lemon  citrus  spicy  waxy  hay  
Taste Description:
at 30.00 ppm.  
Sweet, lemon, citrus, spice, waxy, with a hay-like nuance
Mosciano, Gerard P&F 17, No. 6, 41, (1992)
  
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Cosmetic Information:
None found
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Suppliers:
A. Fakhry
Verbena Absolute
Indukern F&F
VERBENA ABSOLUTE
CROP CALENDAR
Reincke & Fichtner
Verbena Absolute
Robertet
VERBENA
Pure & Nat
The Perfumers Apprentice
Verbena absolute (France) J.Steele
Odor: Rich green lemon notes
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Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

Dermal Toxicity:
skin-rabbit LD50 5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

skin-guinea pig LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavoring agents
IFRA Critical Effect: Sensitization
IFRA fragrance material specification:
 Verbena absolute obtained from Lippia citriodora Kunth, should not be used as a fragrance ingredient at a level over 1% in fragrance compounds. This recommendation is based on test results of RIFM showing sensitization reaction at 12% and no sensitization reaction at 2%. There is no evidence of photoxicity at 100% on hairless mice (private communication to IFRA).
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
citral Max. Found: <5.00 % and Reason: Sensitization
IFRA: View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories: limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1:
See Note (1)
0.05 % (1)
Category 2:  0.06 %
Category 3:  0.20 %
Category 4:  0.20 %
Category 5:  0.20 %
Category 6:  1.20 % (1)
Category 7:  0.12 %
Category 8:  0.20 %
Category 9:  0.20 %
Category 10:  0.20 %
Category 11: See Note (2)
 Notes:
 

For this material, for pragmatic reasons, restrictive levels allowed by the QRA for certain categories but actually being higher than those already in place before applying the QRA, will temporarily not be implemented until the end of a 5 year monitoring phase. At the end of the 5 years the position will be reevaluated again.

 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for verbena absolute france flavor usage levels up to:
  30.0000 ppm in the finished product.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 8024-12-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 2
 lippia citriodora absolute
Chemidplus: 008024122
 aloysia citriodora extract
Chemidplus: 085116638
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References:
 lippia citriodora absolute
Canada Domestic Sub. List: 8024-12-2
Pubchem (sid): 3730676
 aloysia citriodora extract
Canada Domestic Sub. List: 85116-63-8
Pubchem (sid): 3777682
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Other Information:
Export Tariff Code: 3301.90.5000
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 citrusFL
 hay new mown hay foin coupe 
 lemonFL
 tea 
 tobacco tabac tabaco 
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Occurrence (nature, food, other): note
 lippia citriodora
Search Trop  Picture
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Synonyms:
 aloysia triphylla absolute france
 lippia citriodora absolute france
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Articles:
PubMed: Ethnobotanical survey of medicinal plants used by people in Oriental Morocco to manage various ailments.
PubMed: Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats.
PubMed: Comparative study on in vitro activities of citral, limonene and essential oils from Lippia citriodora and L. alba on yellow fever virus.
PubMed: Chromatographic and mass spectrometric characterization of essential oils and extracts from Lippia (Verbenaceae) aromatic plants.
PubMed: Evaluation of different extraction approaches for the determination of phenolic compounds and their metabolites in plasma by nanoLC-ESI-TOF-MS.
PubMed: Antimicrobial activity of food-compatible plant extracts and chitosan against naturally occurring micro-organisms in tomato juice.
PubMed: A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management.
PubMed: Antihyperalgesic activity of verbascoside in two models of neuropathic pain.
PubMed: Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers.
PubMed: Antioxidant effect of lemon verbena extracts in lymphocytes of university students performing aerobic training program.
PubMed: Characterization of phenolic and other polar compounds in a lemon verbena extract by capillary electrophoresis-electrospray ionization-mass spectrometry.
PubMed: Preparation and physicochemical characterization of Ag nanoparticles biosynthesized by Lippia citriodora (Lemon Verbena).
PubMed: Virucidal activity of Colombian Lippia essential oils on dengue virus replication in vitro.
PubMed: Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some yemeni medicinal plants.
PubMed: Authenticity control of essential oils containing citronellal and citral by chiral and stable-isotope gas-chromatographic analysis.
PubMed: Antimicrobial activity of essential oils against Helicobacter pylori.
PubMed: Studies on the antioxidant activity of Lippia citriodora infusion: scavenging effect on superoxide radical, hydroxyl radical and hypochlorous acid.
PubMed: Flavonoids from Lippia citriodora.
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