• Axxence Aromatic
    • Axxence Aromatic GmbH
      Aroma Creators
      Dedicated to provide the best possible quality and supply service of natural aroma ingredients.
      Email:Service
      US Email:Service-usa
      Voice:+49.2822.68561.11
      Fax:+49 2822 68561-39
      US Voice:+1 203 885 7895
      Product(s):
      DIMETHYL DISULFIDE Natural Kosher
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      Email:Sales
      US Email:Sales
      Voice:+86-21-32515501 60762991 60762992
      Fax:+86-21-32515502 64204960
      US Voice:908-359-9000
      US Fax:908-359-9002
      Product(s):
      DIMETHYL DISULFIDE
  • Penta International
  • Robertet
  • SAFC Global
    • SAFC
      Complete Supply chain
      The perfect blend of products and services that bring your creativity to life.
      US Email:Sales
      US Voice:800-244-1173
      US Fax:800-368-4661
      Product(s):
      Dimethyl disulfide ≥98%, Kosher
  • Treatt
    • Treatt PLC
      Full Range of Naturals
      World-leading, independent ingredients supplier to the flavour and fragrance industries.
      Email:Enquiries
      US Email:Enquiries
      Voice:+44 (0) 1284 702500
      Fax:+44 (0) 1284 703809
      US Voice:+1 863 668 9500
      US Fax:+1 863 668 3388
      Product(s):
      Dimethyl Disulphide NI, Kosher
dimethyl disulfide
  • Home
  • Suppliers
  • Organoleptics
      • Organoleptic Properties
        Odor Type :sulfurous
        Odor Strength :high ,
        recommend smelling in a 0.10 % solution or less
        Odor Description:
        at 0.10 % in propylene glycol. 
        sulfurous vegetable cabbage onion
  • Properties
      • Physical Properties
        Appearance :colorless to pale yellow clear liquid (est)
        Assay : 97.00 to 100.00 % 
        Food Chemicals Codex Listed :No
        Specific Gravity :1.05500 to 1.06500 @  20.00 °C.
        Pounds per Gallon - (est). : 8.789 to  8.872
        Refractive Index :1.51500 to 1.53500 @  20.00 °C.
        Melting Point : -85.00 °C. @ 760.00 mm Hg
        Boiling Point : 109.00 to  110.00 °C. @ 760.00 mm Hg
        Boiling Point : 23.00 °C. @ 30.00 mm Hg
        Vapor Pressure :28.733000 mm/Hg @ 25.00 °C. (est)
        Vapor Density :3.2 ( Air = 1 )
        Flash Point : 76.00 °F. TCC ( 24.44 °C. )
        logP (o/w) : 1.770
  • Safety
      • Safety Information
        Most important hazard(s) :Xn N - Harmful, Dangerous for the environment.
          R 11 - Highly flammable.
        R 20/22 - Harmful by inhalation and if swallowed.
        R 36 - Irritating to eyes.
        R 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
        S 02 - Keep out of the reach of children.
        S 16 - Keep away from sources of ignition - No Smoking.
        S 20/21 - When using do not eat, drink or smoke.
        S 24/25 - Avoid contact with skin and eyes.
        S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
        S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
        S 60 - This material and its container must be disposed of as hazardous waste.
        Oral/Parenteral Toxicity : 
          oral-rat LD50  [sex: M,F] 190 mg/kg
        (Shapiro et al., 1985)

        unreported-mammal (species unspecified) LD50  138 mg/kg
        Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 16(6), Pg. 46, 1972.

        Dermal Toxicity : 
          Not determined
        Inhalation Toxicity : 
          inhalation-rat LC50 15850 ug/m3/2H
        Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 16(6), Pg. 46, 1972.

        inhalation-mouse LC50 12300 ug/m3/2H
        Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 16(6), Pg. 46, 1972.

  • Safety in Use
      • Safety in Use Information
        Category :flavoring agents
        Maximised Survey-derived Daily Intakes (MSDI-EU) :6.90 (μg/capita/day)
        Structure Class :I
        Recommendation for dimethyl disulfide fragrance usage levels up to :
         not for fragrance use.
        Recommendation for dimethyl disulfide flavor usage levels up to :
          1.0000 ppm in the finished product.
  • Safety References
      • Safety References
        European Food Safety Athority(efsa) :Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
        European Food Safety Authority (EFSA) reference(s) :
        Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20:page or pdf
        Flavouring Group Evaluation 74 (FGE.74)[1]: Consideration of Simple Aliphatic Sulphides and Thiols evaluated by JECFA (61st meeting) Structurally related to Aliphatic and Alicyclic Mono-, Di-, Tri-, and Polysulphides with or without Additional Oxygenated Functional Groups from Chemical Group 20 evaluated by EFSA in FGE.08 (2008):page or pdf
        Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30:page or pdf
        Flavouring Group Evaluation 91 (FGE.91): Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by EFSA in FGE.08Rev1 (2009):page or pdf
        Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30:page or pdf
        Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30:page or pdf
        EPI System :View
        Chemicalize.org :Calculate predicted properties
        IUCLID Chemical Data Sheet :View
        NIOSH International Chemical Safety Cards :search
        NLM Hazardous Substances Data Bank :Search
        Chemical Carcinogenesis Research Information System :Search
        Cancer Citations :Search
        Toxicology Citations :Search
        NLM Developmental and Reproductive Toxicity :Search
        National Toxicology Program :Search
        Canada Domestic Sub. List :Yes
        EPA Substance Registry Services (TSCA) :624-92-0
        WISER :UN 2381
        WGK Germany :2
         methyldisulfanylmethane
        DTP/NCI :9370
        Chemidplus :0000624920
        EPA/NOAA CAMEO :hazardous materials
        RTECS :624-92-0
methyldisulfanylmethane (Click)
CAS Number : 624-92-0
ESIS EC# (EINECS) :210-871-0
Beilstein Number :1730824
CoE Number :2175
XlogP3 :1.80 (est)
Molecular Weight :94.19982000
Formula :C2 H6 S2
BioActivity Summary :listing
NMR Predictor :Predict
Category :flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
Google Scholar : Search Google Books : Search
Google Scholar : with word "volatile"Search Google Scholar : with word "flavor"Search
Google Scholar : with word "odor"SearchPerfumer and Flavorist : Search
Google Patents : Search US Patents : Search
EU Patents : Search IBM Patents : Obtain
Pubchem Patents:Search
PubMed : SearchNCBI : Search
EU SANCO Food Flavourings :Search
JECFA Food Flavoring :564  dimethyl disulfide
FEMA Number :3536  dimethyl disulfide
FDA Mainterm : METHYL DISULFIDE
FDA Regulation :FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
click on the picture(s) below to interact with the 3D model
Picture of molecule
methyldisulfanylmethane
Synonyms :
 dimethyl disulfane
 dimethyl disulfide natural
 dimethyl disulphide
 disulfide, dimethyl
2,3-dithiabutane
 DMDS
 methyl disulfide
 methyl disulphide
(methyl dithio) methane
 methyl dithiomethane
(methyldisulfanyl)methane
 methyldisulfanylmethane
(methyldithio)methane
 methyldithiomethane
Soluble in :
 alcohol
 water, 3739 mg/L @ 25 °C (est)
 water, 3000 mg/L @ 25 °C (exp)
Insoluble in :
 water
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