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tobacco leaf oil
essential oil obtained from the leaves of the tobacco, nicotiana tabacum l., solanaceae

Supplier Sponsors

Name:	nicotiana tabacum l. leaf oil
CAS Number:	8037-19-2
Other(deleted CASRN):	8031-12-7
FDA UNII:	6YR2608RSU
Also Contains:	nicotiana tabacum leaf extract

Category:fragrance agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Food Chemicals Codex Listed:	No
Soluble in:
	alcohol
	water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
	water

Organoleptic Properties:

Odor Type: tobacco

Odor Description:at 100.00 %. tobacco

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	perfuming agents

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Recommendation for tobacco leaf oil flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

ClinicalTrials.gov:search

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):8037-19-2

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

nicotiana tabacum l. leaf oil

Chemidplus:008037192

References:

	nicotiana tabacum l. leaf oil
Canada Domestic Sub. List:	8037-19-2
Pubchem (sid):	135345085

Other Information:

FAO:	BASIC PRINCIPLES OF STEAM DISTILLATION

Potential Blenders and core components note

For Odor

amber

ambrette seed absolute
FL/FR

animal

animal specialty
FR

2-iso

butyl quinoline
FR

6-

methyl quinoline
FL/FR

procavia capensis excrete absolute
FR

balsamic

amyl phenyl acetate
FL/FR

bready

bran resinoid
FR

caramellic

immortelle absolute
FL/FR

cereal

bran absolute
FR

cheesy

valeric acid
FL/FR

chocolate

iso

butyl phenyl acetate
FL/FR

coconut

alpha-

angelica lactone
FL/FR

coumarinic

floral

boronia butenal
FR

beta-

damascenone
FL/FR

delta-

damascone
FL/FR

ilex paraguariensis oleoresin
FL/FR

tobacco flower absolute
FR

fruity

alpha-

amyl cinnamyl isovalerate
FL/FR

cyclohexanone diethyl acetal
FL/FR

(E)-beta-

damascenone
FL/FR

(E)-beta-

damascone
FL/FR

(Z)-beta-

damascone
FL/FR

beta-

damascone
FL/FR

plum damascone (high alpha)
FR

fungal

methyl 2-furoate
FL/FR

green

3,7-

dimethyl-6-octenoic acid
FL/FR

leafy acetal
FL/FR

marigold pot absolute
FL/FR

yerba mate leaf oil
FL/FR

hay

beeswax absolute
FL/FR

white

beeswax absolute
FL/FR

hay absolute
FR

tobacco absolute replacer
FR

tobacco leaf absolute
FL/FR

woodruff absolute
FR

herbal

saffron indenone
FL/FR

theaspirane
FL/FR

thyme undecane
FR

gamma-

valerolactone
FL/FR

yerba mate absolute
FL/FR

mossy

oakmoss absolute
FL/FR

musk

omega-

pentadecalactone
FL/FR

musty

ketoiso

orris

2(1)-

orris butanal
FL/FR

phenolic

2,3-

dimethyl benzofuran
FL/FR

2'-

hydroxyacetophenone
FL/FR

tobacco specialty
FR

popcorn

2-

acetyl pyridine
FL/FR

spicy

N,N-

diethyl octanamide
FR

machilus kusanoi leaf oil
FR

machilus kusanoi wood oil
FR

tobacco

para-

cresyl isovalerate
FL/FR

deertongue absolute replacer
FR

3-

ethyl pyridine
FL/FR

honey absolute
FL/FR

methyl benzoxole
FL/FR

(E,E/E,Z)-

tobacco cyclohexenone
FL/FR

tobacco fragrance
FR

tobacco oil CO2 extract
FL/FR

tobacco oil nicotine-free
FL/FR

tobacco resinoid
FL/FR

2,6,6-

trimethyl-2-hydroxycyclohexanone
FL/FR

veltonal (Bedoukian)
FR

tonka

deertongue absolute
FR

(±)-

dihydromint lactone
FL/FR

gamma-

hexalactone
FL/FR

melilot absolute
FR

mint lactone
FL/FR

saffron resinoid
FL/FR

tonka undecanone
FR

tropical

beta-

cyclocitral
FL/FR

genet absolute
FL/FR

vanilla

propenyl guaethol
FL/FR

woody

amber decatriene
FR

amber dodecane
FR

alpha-

cedrene epoxide
FR

dihydro-gamma-ionone
FL/FR

iso

longifolene ketone
FR

methyl 2,6,10-trimethyl cyclododeca-2,5,9-trienyl ketone
FR

sclareolide
FL/FR

tobacarol (IFF)
FR

tobacco nonene
FR

woody cyclohexanone
FR

woody nonane (ethoxy)
FR

zdravetz absolute
FR

zdravetz oil
FL/FR

For Flavor

No flavor group found for these

amyl phenyl acetate
FL/FR

cyclohexanone diethyl acetal
FL/FR

(E)-beta-

damascenone
FL/FR

dihydro-gamma-ionone
FL/FR

ilex paraguariensis oleoresin
FL/FR

2(1)-

orris butanal
FL/FR

tobacco oil CO2 extract
FL/FR

2,6,6-

trimethyl-2-hydroxycyclohexanone
FL/FR

yerba mate leaf oil
FL/FR

zdravetz oil
FL/FR

beta-

damascone
FL/FR

acidic

acidic

valeric acid
FL/FR

animal

6-

methyl quinoline
FL/FR

aromatic

leafy acetal
FL/FR

brown

beeswax absolute
FL/FR

caramellic

3-

ethyl pyridine
FL/FR

methyl 2-furoate
FL/FR

chemical

2,3-

dimethyl benzofuran
FL/FR

citrus

ketoiso

cocoa

iso

butyl phenyl acetate
FL/FR

cooling

theaspirane
FL/FR

corn

2-

acetyl pyridine
FL/FR

creamy

alpha-

angelica lactone
FL/FR

gamma-

hexalactone
FL/FR

mint lactone
FL/FR

floral

3,7-

dimethyl-6-octenoic acid
FL/FR

fruity

alpha-

amyl cinnamyl isovalerate
FL/FR

(E)-beta-

damascone
FL/FR

(Z)-beta-

damascone
FL/FR

grassy

tobacco leaf absolute
FL/FR

green

immortelle absolute
FL/FR

marigold pot absolute
FL/FR

oakmoss absolute
FL/FR

hay

white

beeswax absolute
FL/FR

genet absolute
FL/FR

herbal

saffron indenone
FL/FR

yerba mate absolute
FL/FR

honey

honey absolute
FL/FR

lactonic

(±)-

dihydromint lactone
FL/FR

naphthyl

2'-

hydroxyacetophenone
FL/FR

nutty

methyl benzoxole
FL/FR

(E,E/E,Z)-

tobacco cyclohexenone
FL/FR

phenolic

para-

cresyl isovalerate
FL/FR

sweet

saffron resinoid
FL/FR

tobacco

tobacco oil nicotine-free
FL/FR

tobacco resinoid
FL/FR

tonka

gamma-

valerolactone
FL/FR

tropical

beta-

cyclocitral
FL/FR

vanilla

omega-

pentadecalactone
FL/FR

propenyl guaethol
FL/FR

woody

ambrette seed absolute
FL/FR

beta-

damascenone
FL/FR

delta-

damascone
FL/FR

sclareolide
FL/FR

Potential Uses:

None Found

Occurrence (nature, food, other):note

	nicotiana spp. Search Trop Picture
	tobacco Search Trop Picture
	tobacco aztec tobacco Search Trop Picture

Synonyms:

	essential oil obtained from the leaves of the tobacco, nicotiana tabacum l., solanaceae
	nicotiana rustica leaf oil
	nicotiana spp. leaf oil
	nicotiana tabacum leaf oil
	tobacco leaf oil

Articles:

PubMed:Expression of synthetic human tropoelastin (hTE) protein in Nicotiana tabacum.

PubMed:Chlorophyll degradation in the gut of generalist and specialist Lepidopteran caterpillars.

PubMed:Gene-splitting technology: a novel approach for the containment of transgene flow in Nicotiana tabacum.

PubMed:Transcript and metabolite profiling for the evaluation of tobacco tree and poplar as feedstock for the bio-based industry.

PubMed:Biomass derived from transgenic tobacco expressing the Arabidopsis CESA3ixr1-2 gene exhibits improved saccharification.

PubMed:Overexpression of the synthetic chimeric native-T-phylloplanin-GFP genes optimized for monocot and dicot plants renders enhanced resistance to blue mold disease in tobacco (N. tabacum L.).

PubMed:Association of satellites with a mastrevirus in natural infection: complexity of Wheat dwarf India virus disease.

PubMed:Virus-induced gene silencing using a modified betasatellite: a potential candidate for functional genomics of crops.

PubMed:Molecular characterization and pathogenicity of a carrot (Daucus carota) infecting begomovirus and associated betasatellite from India.

PubMed:Metabolic engineering of biomass for high energy density: oilseed-like triacylglycerol yields from plant leaves.

PubMed:Transfructosylation reaction in cured tobacco leaf (Nicotiana tabacum).

PubMed:In-vitro antimicrobial activity screening of some ethnoveterinary medicinal plants traditionally used against mastitis, wound and gastrointestinal tract complication in Tigray Region, Ethiopia.

PubMed:Transformation of apple (Malus × domestica) using mutants of apple acetolactate synthase as a selectable marker and analysis of the T-DNA integration sites.

PubMed:Variable nornicotine enantiomeric composition caused by nicotine demethylase CYP82E4 in tobacco leaf.

PubMed:Altered leaf colour is associated with increased superoxide-scavenging activity in aureusidin-producing transgenic plants.

PubMed:Expression of a bacterial, phenylpropanoid-metabolizing enzyme in tobacco reveals essential roles of phenolic precursors in normal leaf development and growth.

PubMed:Analysis of CoQ10 in cultivated tobacco by a high-performance liquid chromatography-ultraviolet method.

PubMed:Gene transfer into Solanum tuberosum via Rhizobium spp.

PubMed:Analysis of a Nicotiana tabacum L. genomic region controlling two leaf surface chemistry traits.

PubMed:[Hydrogen peroxide is involved in regulation of tobacco leaf senescence].

PubMed:Root-selective expression of AtCAX4 and AtCAX2 results in reduced lamina cadmium in field-grown Nicotiana tabacum L.

PubMed:Identification of sequence elements regulating promoter activity and replication of a monopartite begomovirus-associated DNA beta satellite.

PubMed:Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators.

PubMed:A red algal cyclophilin has an effect on development and growth in Nicotiana tabacum.

PubMed:Molecular farming of human tissue transglutaminase in tobacco plants.

PubMed:Cysteine proteinases regulate chloroplast protein content and composition in tobacco leaves: a model for dynamic interactions with ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) vesicular bodies.

PubMed:Picloram resistance in transgenic tobacco expressing an anti-picloram scFv antibody is due to reduced translocation.

PubMed:Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide.

PubMed:[Relation between the decline of photosynthetic function and H2O2 accumulation in leaf life span of tobacco].

PubMed:A simple and efficient system for green note compound biogenesis by use of certain lipoxygenase and hydroperoxide lyase sources.

PubMed:Isolation by improved thermal asymmetric interlaced PCR and characterization of a seed-specific 2S albumin gene and its promoter from grape (Vitis vinifera L.).

PubMed:Watermelon (Citrullus lanatus) hydroperoxide lyase greatly increases C6 aldehyde formation in transgenic leaves.

PubMed:Stimulation of nicotine demethylation by NaHCO(3) treatment using greenhouse-grown burley tobacco.

PubMed:Enhanced resistance to Helicoverpa zea in tobacco expressing an activated form of maize ribosome- inactivating protein.

PubMed:Overexpression of polygalacturonase in transgenic apple trees leads to a range of novel phenotypes involving changes in cell adhesion.

PubMed:Aflatoxin B1--its effects on an in vitro plant system.

Notes:

tsca definition 2008: extractives and their physically modified derivatives. nicotiana, solanaceae.

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