EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

acetone
dimethyl ketone

Sponsors

Name:propan-2-one
CAS Number: 67-64-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:200-662-2
FDA UNII:1364PS73AF
Nikkaji Web:J2.365E
Beilstein Number:0635680
MDL:MFCD00008765
CoE Number:737
XlogP3-AA:-0.10 (est)
Molecular Weight:58.08002000
Formula:C3 H6 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:extraction solvents, flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:139 acetone
JECFA Food Additive: Acetone
FLAVIS Number:07.050 (Old)
DG SANTE Food Flavourings:07.050 acetone
DG SANTE Food Contact Materials:acetone
FEMA Number:3326 acetone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm: ACETONE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart C--Solvents, Lubricants, Release Agents and Related Substances
Sec. 173.210 Acetone.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.320 Resinous and polymeric coatings for polyolefin films.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.180 Components of paper and paperboard in contact with dry food.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.300 Slimicides.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2600 Rubber articles intended for repeated use.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.100 Cochineal extract; carmine.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.300 Carrot oil.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.345 Paprika oleoresin.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.615 Turmeric oleoresin.
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity:0.78800 to 0.79200 @ 25.00 °C.
Pounds per Gallon - (est).: 6.557 to 6.590
Refractive Index:1.34700 to 1.35900 @ 20.00 °C.
Melting Point: -95.00 to -94.00 °C. @ 760.00 mm Hg
Boiling Point: 56.00 to 57.00 °C. @ 760.00 mm Hg
Boiling Point: 22.00 to 23.00 °C. @ 200.00 mm Hg
Vapor Pressure:232.000000 mm/Hg @ 25.00 °C.
Vapor Density:2.0 ( Air = 1 )
Flash Point: 1.00 °F. TCC ( -17.22 °C. )
logP (o/w): -0.160
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 water, 2.199e+005 mg/L @ 25 °C (est)
 water, 1.00E+06 mg/L @ 25 °C (exp)
Similar Items:note
acetone alcohol
 
Organoleptic Properties:
Odor Type: solvent
Odor Strength:high ,
recommend smelling in a 1.00 % solution or less
Substantivity: < 1 hour(s) at 100.00 %
solvent ethereal apple pear
Odor Description:at 1.00 % in propylene glycol. solvent ethereal apple pear
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: denaturants
solvents
 
Suppliers:
Advanced Biotech
ACETONE NATURAL
99% min.
Odor: Aromatic; pungent
Alfrebro
ACETONE NATURAL
Odor: Characteristic Odor, Pungent
Axxence Aromatic
ACETONE MIN. 99%, Natural
Sustainability
Covalent Chemical
Acetone
Diffusions Aromatiques
ACETONE
Excellentia International
Acetone Natural
Fleurchem
acetone natural
Lluch Essence
ACETONE
Odor: ETHEREAL, APPLE, PINEAPPLE
M&U International
NAT. ACETONE
Norman, Fox & Co.
ACETONE 75%
Norman, Fox & Co.
Acetone
Novapex
Acetone Premium
Novapex
Acetone
Odowell Co.,ltd
Natural Acetone
Penta International
ACETONE FCC, Kosher
Penta International
ACETONE REAGENT ACS GRADE, Kosher
Penta International
ACETONE, NATURAL, Kosher
Sigma-Aldrich
Acetone, ≥99%, meets FCC analytical specifications
Odor: apple; ethereal
Certified Food Grade Products
Sigma-Aldrich
Acetone, natural, ≥97%
Odor: apple; ethereal
Silver Fern Chemical
Acetone
Odor: characteristic
Use: Because it is miscible with water, acetone is often used as a cleaning solvent. Acetone is also a common paint thinner and a common building block in organic chemistry.
TCI AMERICA
For experimental / research use only.
Acetone [for Spectrophotometry] >99.5%(GC)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 11 - Highly flammable.
R 36 - Irritating to eyes.
R 66 - Repeated exposure may cause skin dryness or cracking.
R 67 - Vapours may cause frowsiness and dizziness.
S 02 - Keep out of the reach of children.
S 09 - Keep container in a well-ventilated place.
S 16 - Keep away from sources of ignition - No Smoking.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 [sex: M] 8452 mg/kg
(Smyth et al., 1970)

oral-rat LD50 8930 mg/kg
(Smyth et al., 1969b)

oral-rat LD50 9750 mg/kg
(FDA, 1975a)

oral-rat LD50 6800 mg/kg
(Kimura et al., 1971a)

oral-rat LD50 3465 mg/kg
(Kohli et al., 1967)

oral-mouse LD50 [sex: M] 5250 mg/kg
(Tanii et al., 1986)

oral-rabbit LD50 5300 mg/kg
(Krasavage et al., 1982)

intraperitoneal-dog LDLo 8000 mg/kg
BEHAVIORAL: COMA GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 18, Pg. 218, 1884.

oral-dog LDLo 8000 mg/kg
MUSCULOSKELETAL: JOINTS BEHAVIORAL: COMA BEHAVIORAL: ATAXIA
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 18, Pg. 218, 1884.

oral-man TDLo 2857 mg/kg
BEHAVIORAL: COMA KIDNEY, URETER, AND BLADDER: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 64, 1969.

oral-man TDLo 2857 mg/kg
BEHAVIORAL: COMA
Diabetes. Vol. 15, Pg. 810, 1966.

intraperitoneal-mouse LD50 1297 mg/kg
Shell Chemical Company. Unpublished Report. Vol. -, Pg. 1, 1961.

oral-mouse LD50 3000 mg/kg
Pharmaceutical Chemistry Journal Vol. 14, Pg. 162, 1980.

intravenous-mouse LDLo 4000 mg/kg
FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 86, 1970.

oral-rabbit LD50 5340 mg/kg
FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 86, 1970.

intravenous-rabbit LDLo 1576 mg/kg
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 33, Pg. 175, 1928.

intravenous-rat LD50 5500 mg/kg
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 1, 1974.

oral-rat LD50 5800 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: TREMOR
Journal of Toxicology and Environmental Health. Vol. 15, Pg. 609, 1985.

intraperitoneal-rat LDLo 500 mg/kg
KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: MUSCLE WEAKNESS
Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959.

Dermal Toxicity:
skin-rabbit LDLo 20 ml/kg
Union Carbide Data Sheet. Vol. 5/7/1970

skin-guinea pig LD50 > 9.40 ml/kg
Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.

subcutaneous-dog LDLo 5000 mg/kg
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 18, Pg. 218, 1884.

skin-guinea pig LD50 > 9400 uL/kg
Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.

subcutaneous-guinea pig LDLo 5000 mg/kg
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.

Inhalation Toxicity:
inhalation-rat LC50 50100 mg/m3/8H
American Industrial Hygiene Association Journal. Vol. 20, Pg. 364, 1959.

inhalation-mouse LC50 44 gm/m3/4H
Current Toxicology. Vol. 1, Pg. 47, 1993.

inhalation-human TCLo 500 ppm
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.

inhalation-man TCLo 440 ug/m3/6M
BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(8), Pg. 42, 1977.

inhalation-man TCLo 10 mg/m3/6H
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(8), Pg. 42, 1977.

inhalation-man TCLo 12000 ppm/4H
BEHAVIORAL: MUSCLE WEAKNESS GASTROINTESTINAL: NAUSEA OR VOMITING
Annals of Occupational Hygiene. Vol. 16, Pg. 73, 1973.

inhalation-mouse LC50 44000 mg/m3/4H
Current Toxicology. Vol. 1, Pg. 47, 1993.

 
Safety in Use Information:
Category: extraction solvents, flavoring agents
Recommendation for acetone usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 6100.00 (μg/capita/day)
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 6
 average usual ppmaverage maximum ppm
baked goods: -8.00000
beverages(nonalcoholic): -5.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -5.00000
fruit ices: -5.00000
gelatins / puddings: -5.00000
granulated sugar: --
gravies: --
hard candy: -8.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: -5.00000
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf

Flavouring Group Evaluation 63 (FGE.63): Consideration of aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th meeting) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids evaluated by EFSA in FGE.07 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf

Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf

EPI System: View
EPA-Iris:IRIS
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):67-64-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :180
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 1090
WGK Germany:1
propan-2-one
Chemidplus:0000067641
EPA/NOAA CAMEO:hazardous materials
RTECS:67-64-1
 
References:
 propan-2-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:67-64-1
Pubchem (cid):180
Pubchem (sid):134970724
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
UM BBD:Search
KEGG (GenomeNet):C00207
HMDB (The Human Metabolome Database):HMDB01659
FooDB:FDB008301
Export Tariff Code:2914.11.5000
FDA Listing of Food Additive Status:View
Haz-Map:View
Household Products:Search
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
For Odor
animal
methyl (E)-2-octenoate
FL/FR
ethereal
methyl acetate
FL/FR
methyl ethyl ketone
FL/FR
iso
propyl formate
FL/FR
floral
hexyl 2-furoate
FL/FR
fruity
amyl acetate
FL/FR
amyl hexanoate
FL/FR
apple crotonate
FR
apple specialty
FR
iso
butyl acetate
FL/FR
butyl isovalerate
FL/FR
ethyl (E)-2-decenoate
FL/FR
(Z)-3-
hexen-1-yl isobutyrate
FL/FR
hexyl (E)-tiglate
FL/FR
hexyl isovalerate
FL/FR
2-
methyl butyl butyrate
FL/FR
methyl hexanoate
FL/FR
propyl heptanoate
FL/FR
green
ethyl (E,Z)-2,4-decadienoate
FL/FR
green note propionate
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(E)-2-
hexen-1-yl isovalerate
FL/FR
(E)-2-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl valerate
FL/FR
hexyl isobutyrate
FL/FR
methyl (E)-3-hexenoate
FL/FR
3-
octyl formate
FL/FR
sorbyl isobutyrate
FL/FR
(E,E)-
sorbyl isobutyrate
FL/FR
tropical
ethyl (Z)-3-hexenoate
FL/FR
waxy
(E)-2-
tridecen-1-yl acetate
FL/FR
For Flavor
No flavor group found for these
9-
decen-2-one
FL
ethyl (Z)-3-hexenoate
FL/FR
(E,E)-
sorbyl isobutyrate
FL/FR
(E)-2-
tridecen-1-yl acetate
FL/FR
sorbyl isobutyrate
FL/FR
chemical
chemical
methyl ethyl ketone
FL/FR
cocoa
2-
methyl furan
FL
ethereal
methyl acetate
FL/FR
fishy
3-
penten-2-one
FL
fruity
amyl acetate
FL/FR
amyl hexanoate
FL/FR
iso
butyl acetate
FL/FR
butyl isovalerate
FL/FR
ethyl (E)-2-decenoate
FL/FR
(Z)-3-
hexen-1-yl isobutyrate
FL/FR
methyl (E)-2-octenoate
FL/FR
2-
methyl butyl butyrate
FL/FR
methyl hexanoate
FL/FR
iso
propyl formate
FL/FR
green
ethyl (E,Z)-2,4-decadienoate
FL/FR
2-
ethyl-5-methyl thiophene
FL
green note propionate
FL/FR
(Z)-3-
hexen-1-yl acetate
FL/FR
(E)-2-
hexen-1-yl isovalerate
FL/FR
(Z)-3-
hexen-1-yl propionate
FL/FR
(E)-2-
hexen-1-yl propionate
FL/FR
(Z)-3-
hexen-1-yl valerate
FL/FR
hexyl (E)-tiglate
FL/FR
hexyl 2-furoate
FL/FR
hexyl isobutyrate
FL/FR
hexyl isovalerate
FL/FR
methyl (E)-3-hexenoate
FL/FR
waxy
3-
octyl formate
FL/FR
propyl heptanoate
FL/FR
 
Potential Uses:
 denaturants
 solvents
 
Occurrence (nature, food, other):note
 allspice plant
Search Trop Picture
 apple fruit
Search Trop Picture
 apple fruit juice
Search Trop Picture
 apple plant
Search Trop Picture
 bay laurel leaf
Search Trop Picture
 beer
Search PMC Picture
 bread white bread
Search PMC Picture
 broccoli asparagus broccoli leaf
Search Trop Picture
 broccoli asparagus broccoli root
Search Trop Picture
 butter
Search PMC Picture
 cabbage leaf
Search Trop Picture
 carrot root
Search Trop Picture
 cedarwood atlas
Search Trop Picture
 cheese cheddar cheese
Search PMC Picture
 cheese swiss cheese
Search PMC Picture
 clove
Search Trop Picture
 cocoa leaf
Search Trop Picture
 coriander
Search Trop Picture
 currant black currant fruit
Search Trop Picture
 ginger oil
Search Trop Picture
 ginger rhizome
Search Trop Picture
 ginger rhizome oil
Search Trop Picture
 goosefoot
Search Trop Picture
 grape
Search Trop Picture
 guava fruit
Search Trop Picture
 lavandin oil abrialis @ 0.02%
Data GC Search Trop Picture
 lavandin oil grosso @ trace%
Data GC Search Trop Picture
 lavender
Search Trop Picture
 lavender oil spike france @ 0.11%
Data GC Search Trop Picture
 lemongrass plant
Search Trop Picture
 mushroom giant puffball mushroom
Search PMC Picture
 onion
Search Trop Picture
 orange bitter orange
Search Trop Picture
 paprika
Search PMC Picture
 pear fruit
Search Trop Picture
 pear plant
Search Trop Picture
 pineapple fruit
Search Trop Picture
 potato chip
Search PMC Picture
 potato plant
Search Trop Picture
 raspberry red raspberry fruit
Search Trop Picture
 rice cooked rice
Search PMC Picture
 rice plant
Search Trop Picture
 soybean plant
Search Trop Picture
 spearmint oil
Search Trop Picture
 strawberry wild strawberry fruit
Search Trop Picture
 tagete flower oil rwanda @ trace%
Data GC Search Trop Picture
 tagete oil rwanda @ 0.63%
Data GC Search Trop Picture
 tea leaf
Search Trop Picture
 tomato fruit
Search Trop Picture
 turpentine
Search PMC Picture
 water mint leaf
Search Trop Picture
 yogurt
Search PMC Picture
 
Synonyms:
 acetone 99%, (naturals)
 acetone FCC
 acetone min. 99%, natural
 acetone natural
 acetone, natural
 chevron acetone
 dimethyl formaldehyde
 dimethyl ketal
 dimethyl ketone
 dimethylformaldehyde
 dimethylketal
 ketone propane
 ketone, dimethyl
 methyl ketone
 propan-2-one
2-oxopropane
beta-ketopropane
 propanone
2-propanone
 pyroacetic acid
 pyroacetic ether
 

Articles:

PubMed:Ultrahigh performance liquid chromatography analysis of volatile carbonyl compounds in virgin olive oils.
PubMed:The effect of germination on phenolic content and antioxidant activity of chickpea.
PubMed:Milk volatile organic compounds and fatty acid profile in cows fed timothy as hay, pasture, or silage.
PubMed:Headspace volatile components of Canadian grown low-tannin faba bean (Vicia faba L.) genotypes.
PubMed:Biological activity and fatty acid composition of Caesar's mushroom.
PubMed:Formulation and evaluation of microsphere based oro dispersible tablets of itopride hcl.
PubMed:Determination of 3-methyl-2,4-nonanedione in red wines using methanol chemical ionization ion trap mass spectrometry.
PubMed:Monitoring of cocoa volatiles produced during roasting by selected ion flow tube-mass spectrometry (SIFT-MS).
PubMed:Variation in phenolic composition and antioxidant activity during flower development of safflower (Carthamus tinctorius L.).
PubMed:Volatile flavor compounds in yogurt: a review.
PubMed:Chemical and biochemical study of industrially produced San Simón da Costa smoked semi-hard cow's milk cheeses: Effects of storage under vacuum and different modified atmospheres.
PubMed:Flavor authentication studies of alpha-ionone, beta-ionone, and alpha-ionol from various sources.
PubMed:An efficient oxidative lactonization of 1,4-diols catalyzed by Cp*Ru(PN) complexes.
PubMed:Development of a LC-ESI/MS/MS assay for the quantification of vanillin using a simple off-line dansyl chloride derivatization reaction to enhance signal intensity.
PubMed:[Determination of major flavor components in chinese spirits using a special domestic gas chromatograph with DNP packed column].
PubMed:A simple and efficient system for green note compound biogenesis by use of certain lipoxygenase and hydroperoxide lyase sources.
PubMed:Flavor release measurement from gum model system.
PubMed:C-27 apocarotenoids in the flowers of Boronia megastigma (Nees).
PubMed:Flavor release measurement by atmospheric pressure chemical ionization ion trap mass spectrometry, construction of interface and mathematical modeling of release profiles.
PubMed:Headspace gas chromatography-mass spectrometry of volatile compounds in murici (Byrsonima crassifolia l. Rich).
PubMed:Flavor composition of cashew (Anacardium occidentale) and marmeleiro (Croton species) honeys.
PubMed:Simple and rapid analysis for quantitation of the most important volatile flavor compounds in yogurt by headspace gas chromatography-mass spectrometry.
PubMed:Formation of volatile compounds during heating of spice paprika (Capsicum annuum) powder.
PubMed:Enzymatic synthesis of stable, odorless, and powdered furanone glucosides by sucrose phosphorylase.
PubMed:Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice.
PubMed:Effect of ethanol in feed on milk flavor and chemical composition.
PubMed:Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites.
PubMed:[Shortened dough preparation of wheat bread and its effect on the flavor. 1. Carbonyl compounds and ethanol].
 
Notes:
a colorless liquid used as a solvent and an antiseptic. it is one of the ketone bodies produced during ketoacidosis. a colorless liquid used as a solvent and an antiseptic. it is one of the ketone bodies produced during ketoacidosis. Solvent used in food processing as a colour diluent, flavour ingredient, etc. Acetone evaporates rapidly, even from water and soil. Once in the atmosphere, it is degraded by UV light with a 22-day half-life. Acetone dissipates slowly in soil, animals, or waterways since it is sometimes consumed by microorganisms; however, it is a significant issue with respect to groundwater contamination due to its high solubility in water. The LD50 of acetone for fish is 8.3 g/l of water (or about 0.8%) over 96 hours, and its environmental half-life is about 1 to 10 days. Acetone may pose a significant risk of oxygen depletion in aquatic systems due to the microbial activity consuming it.; Acetone is a good solvent for most plastics and synthetic fibres including those used in Nalgene bottles made of polystyrene, polycarbonate and some types of polypropylene.. It is ideal for thinning fiberglass resin, cleaning fiberglass tools and dissolving two-part epoxies and superglue before hardening. It is used as a volatile component of some paints and varnishes. As a heavy-duty degreaser, it is useful in the preparation of metal prior to painting; it also thins polyester resins, vinyl and adhesives.; Acetone is often the primary component in cleaning agents such as nail polish remover. Ethyl acetate, another organic solvent, is sometimes used as well. Acetone is a component of superglue remover and it easily removes residues from glass and porcelain.; Acetone is one of the ketone bodies produced during ketoacidosis. Acetone is not regarded as a waste product of metabolism. However, its physiological role in biochemical machinery is not clear. A model for the role of acetone metabolism is presented that orders the events occurring in acetonemia in sequence: in diabetic ketosis or starvation, ketone body production (b-hydroxy-butyrate, acetoacetate) provides fuel for vital organs (heart, brain . . .) raising the chance of survival of the metabolic catastrophe. However, when ketone body production exceeds the degrading capacity, the accumulating acetoacetic acid presents a new challenge to the pH regulatory system. Acetone production and its further degradation to C3 fragments fulfill two purposes: the maintenance of pH buffering capacity and provision of fuel for peripheral tissues. Since ketosis develops under serious metabolic circumstances, all the mechanisms that balance or moderate the effects of ketosis enhance the chance for survival. From this point of view, the theory that transportable C3 fragments can serve as additional nutrients is a novel view of acetone metabolism which introduces a new approach to the study of acetone degradation, especially in understanding its physiological function and the interrelationship between liver and peripheral tissues. (PMID 10580530). Acetone is typically derived from acetoacetate through the action of microbial acetoacetate decarboxylases found in gut microflora.; In chemistry, acetone is the simplest representative of the ketones. Acetone is a colorless, mobile, flammable liquid readily soluble in water, ethanol, ether, etc., and itself serves as an important solvent. ; Acetone is an irritant and inhalation may lead to hepatotoxic effects (causing liver damage).; Acetone is the organic compound with the formula OC(CH3)2. This colorless, mobile, flammable liquid is the simplest example of the ketones. Owing to the fact that acetone is miscible with water, and virtually all organic solvents, it serves as an important solvent in its own right, typically the solvent of choice for cleaning purposes in the laboratory. More than 3 billion kilograms are produced annually, mainly as a precursor to polymers. Familiar household uses of acetone are as the active ingredient in nail polish remover and as paint thinner and sanitary cleaner/ nail polish remover base. It is a common building block in organic chemistry. In addition to being manufactured, acetone also occurs naturally, even being biosynthesized in small amounts in the human body.; Bisphenol-A is a component of many polymers such as polycarbonates, polyurethanes, and epoxy resins.; In the laboratory, acetone is used as a polar aprotic solvent in a variety of organic reactions, such as SN2 reactions. The use of acetone solvent is also critical for the Jones oxidation. It is a common solvent for rinsing laboratory glassware because of its low cost, volatility, and ability to dissolve water. For similar reasons, acetone is also used as a drying agent. Acetone can be cooled with dry ice to -78 C without freezing; acetone/dry ice baths are commonly used to conduct reactions at low temperatures. Acetone is fluorescent under ultraviolet light, and acetone vapor may be used as a fluorescent tracer in fluid flow experiments.; When oxidized, acetone forms acetone peroxide as a byproduct, which is a highly unstable compound. It may be formed accidentally, e.g. when waste hydrogen peroxide is poured into waste solvent containing acetone. Acetone peroxide is more than ten times as friction and shock sensitive as nitroglycerin. Due to its instability, it is rarely used, despite its easy chemical synthesis.
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