Name: 3-methyl-6-propan-2-ylcyclohex-2-en-1-ol
CAS Number: 491-04-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 207-725-3
Nikkaji Web: J6.049F
CoE Number: 10248
XlogP3-AA: 2.10 (est)
Molecular Weight: 154.25266000
Formula: C10 H18 O
NMR Predictor: Predict (works with chrome or firefox)
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 434 p-menth-1-en-3-ol
Flavis Number: 02.083 (Old)
DG SANTE Food Flavourings: 02.083 p-menth-1-en-3-ol
FEMA Number: 3179 p-menth-1-en-3-ol
FDA Mainterm: P-MENTH-1-EN-3-OL
Physical Properties:
Appearance: white to pale amber crystals (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.93000 to 0.93600 25.00 °C.
Pounds per Gallon - (est).: 7.739 to 7.788
Refractive Index: 1.47620 @ 25.00 °C.
Melting Point: 96.00 to 97.00 °C. @ 760.00 mm Hg
Boiling Point: 230.00 to 232.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.020000 mm/Hg @ 25.00 °C. (est)
Flash Point: 193.00 °F. TCC ( 89.44 °C. )
logP (o/w): 2.919 (est)
Soluble in:
 water, 360.2 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
Odor Description:
at 10.00 % in dipropylene glycol.
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: flavoring agents
Recommendation for piperitol usage levels up to:
 not for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.02 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): -20.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -20.00000
fruit ices: -20.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -20.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of alicyclic substances used as flavor ingredients.View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 212: alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 212 Revision 1 (FGE.212Rev1): alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19.
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 212 Revision 3 (FGE.212Rev3): a,-unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19
View page or View pdf
EPI System: View
NLM Hazardous Substances Data Bank: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 491-04-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 10282
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0000491043
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 491-04-3
Pubchem (cid): 10282
Pubchem (sid): 134976467
Flavornet: 491-04-3
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): HMDB35838
FooDB: FDB014609
Haz-Map: View
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Potential Blenders and core components note
For Odor
privet dioxane
herbal acetal
cistus twig/leaf absolute
patchouli absolute
woody acetate
For Flavor
Potential Uses:
Occurrence (nature, food, other): note
 artemisia deserti krasch. oil iran @ 1.40%
Data GC Search Trop Picture
 cascarilla bark oil @ 0.10%
Data GC Search Trop Picture
 cumin seed
Search Trop Picture
 dill leaf
Search Trop Picture
 eucalyptus camaldulensis dehn. leaf oil jerusalem @ 0.10%
Data GC Search Trop Picture
 horsemint plant
Search Trop Picture
 mentha longifolia plant
Search Trop Picture
2-cyclohexen-1-ol, 3-methyl-6-(1-methylethyl)-
3-hydroxy-4-isopropyl-1-methyl cyclohexene
3-methyl-6-(1-methyl ethyl)-2-cyclohexen-1-ol
3-methyl-6-propan-2-yl cyclohex-2-en-1-ol
6-(isopropyl)-3-methyl cyclohex-2-en-1-ol


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PubMed: Fragrance material review on 4-carvomenthenol.
PubMed: Hinokinin biosynthesis in Linum corymbulosum Reichenb.
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PubMed: Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin.
PubMed: Sesamin metabolites induce an endothelial nitric oxide-dependent vasorelaxation through their antioxidative property-independent mechanisms: possible involvement of the metabolites in the antihypertensive effect of sesamin.
PubMed: Supercritical carbon dioxide extraction of compounds with antimicrobial activity from Origanum vulgare L.: determination of optimal extraction parameters.
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PubMed: Chemical constituents and biological activities of Zanthoxylum usambarense.
PubMed: [GC-MS analysis of supercritical carbon dioxide extraction products from pericarp of Zanthoxylum bungeanum].
PubMed: Separation and NMR studies on lignans of Raulinoa echinata.
PubMed: Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum.
PubMed: Evaluation of the trypanocidal activity of lignans isolated from the leaves of Zanthoxylum naranjillo.
PubMed: Insecticidal activity of monoterpenoids to western corn rootworm (Coleoptera: Chrysomelidae), twospotted spider mite (Acari: Tetranychidae), and house fly (Diptera: Muscidae).
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PubMed: (+)-Piperitol from Paulownia tomentosa.
Flavouring material with a pungent taste
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