marrubium vulgare extract
horehound extract

Sponsors

Name: marrubium vulgare l. extract
CAS Number: 84696-20-8
ECHA EC Number: 283-638-4
Category: cosmetic and flavor agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2581 horehound extract
FDA Mainterm: HOREHOUND EXTRACT (MARRUBIUM VULGARE L.)
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Flavor Type: herbal
 horehound
Taste Description:
horehound
Odor and/or flavor descriptions from others (if found).
Frutarom
Horehound Extract
Taste Description: Herbal, Tea-like, Jammy, Fruity
 
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
soothing agents
 
Suppliers:
AuNutra® Industries
Horehound Marrubium Vulgare P.E.
Bio-Botanica®
Horehound Herb Marrubium Vulgare Extract
Bio-Botanica®
Horehound with Caramel color, SE – 2071A
Bio-Botanica®
Horehound without caramel color, SE – 2071B
Bio-Botanica®
Horehound, FE – 5067
Bio-Botanica®
Organic Horehound in Glycerin – 3272ORG
Carrubba
horehound extract
Changsha Organic Herb
Marrubium vulgare horehound Extract
Frutarom
Horehound Extract
Flavor: Herbal, Tea-like, Jammy, Fruity
Grau Aromatics
WHITE HORE HOUND WORT EXTRACT HS 3350 G
(hydrosoluble)
H. Erhard Wagner
PhytoVital-Horehound
Naturex
Horehound Extract
NAT arom®, liquid or powder forms
Penta International
HOREHOUND EXTRACT, SOLID (Marrubium vulgare Linne) Botanical Division, NATURAL, Kosher
SRS Aromatics
WHITE HORE HOUND WORT EXTRACT HS 3350 G
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic and flavor agents
Recommendation for marrubium vulgare extract usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -2.00000
beverages(nonalcoholic): -8.70000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -2.00000
fruit ices: -2.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -680.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 marrubium vulgare l. extract
Chemidplus: 0084696208
 
References:
 marrubium vulgare l. extract
Pubchem (sid): 135354729
 
Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
Export Tariff Code: 1302.19.0000
Wikipedia: View
 
Potential Blenders and core components note
For Odor
For Flavor
absinthe
absinthe flavor
FL
fruity
tamarindus indica extract
FL
herbal
horehound flavor
FL
marrubium vulgare solid extract
FL
marrubium vulgare tincture
FL
tropical
guava distillates
FL
 
Potential Uses:
 skin conditioning 
 soothing agents 
 
Occurrence (nature, food, other): note
 marrubium vulgare
Search Trop Picture
 
Synonyms:
 extract of the herb of the horehound, marrubium vulgare l., labiatae
 hoarhound extract (marrubium vulgare)
 hore hound extract
white hore hound wort extract
 horehound extract
white horehound extract
 horehound extract, solid (marrubium vulgare linne)
 horehound marrubium vulgare P.E.
 

Articles:

PubMed: Chemical constituents of Marrubium vulgare as potential inhibitors of nitric oxide and respiratory burst.
PubMed: Marrubium vulgare L. methanolic extract inhibits inflammatory response and prevents cardiomyocyte fibrosis in isoproterenol-induced acute myocardial infarction in rats.
PubMed: Anti-Trypanosoma cruzi activity of 10 medicinal plants used in northeast Mexico.
PubMed: Cardioprotective effect of methanolic extract of Marrubium vulgare L. on isoproterenol-induced acute myocardial infarction in rats.
PubMed: Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor γ agonist.
PubMed: Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
PubMed: Compositional analysis and in vivo anti-diabetic activity of wild Algerian Marrubium vulgare L. infusion.
PubMed: Gastroprotective activity of methanol extract and marrubiin obtained from leaves of Marrubium vulgare L. (Lamiaceae).
PubMed: Marrubium vulgare extract inhibits human-LDL oxidation and enhances HDL-mediated cholesterol efflux in THP-1 macrophage.
PubMed: Antioxidant and free radical scavenging activities of some medicinal plants from the Lamiaceae.
PubMed: Anti-proliferative effect of horehound leaf and wild cherry bark extracts on human colorectal cancer cells.
PubMed: Bactericidal activity of organic extracts from Flourensia cernua DC against strains of Mycobacterium tuberculosis.
PubMed: Mercury bioaccumulation and phytotoxicity in two wild plant species of Almadén area.
PubMed: Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics.
PubMed: Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat.
PubMed: Comparison of the total antioxidant content of 30 widely used medicinal plants of New Mexico.
PubMed: Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants.
PubMed: Pharmacological evidence of hypotensive activity of Marrubium vulgare and Foeniculum vulgare in spontaneously hypertensive rat.
PubMed: Analysis of the antinociceptive properties of marrubiin isolated from Marrubium vulgare.
PubMed: Analgesic profile of hydroalcoholic extract obtained from Marrubium vulgare.
PubMed: Antispasmodic effects of hydroalcoholic extract of Marrubium vulgare on isolated tissues.
 
Notes:
None found
 
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