EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

formaldehyde diethyl acetal
ethane, 1,1'-[methylenebis(oxy)]bis-

Supplier Sponsors

Name:ethoxymethoxyethane
CAS Number: 462-95-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-330-6
FDA UNII:56IT408V5Y
Nikkaji Web:J5.772J
Beilstein Number:1697253
MDL:MFCD00009246
CoE Number:10012
XlogP3:0.80 (est)
Molecular Weight:104.14904000
Formula:C5 H12 O2
NMR Predictor:Predict (works with chrome or firefox)
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
FLAVIS Number:06.064 (Old)
DG SANTE Food Flavourings:06.064 diethoxymethane
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.82700 to 0.83300 @ 25.00 °C.
Pounds per Gallon - (est).: 6.881 to 6.931
Refractive Index:1.37000 to 1.37900 @ 20.00 °C.
Melting Point: -66.00 °C. @ 760.00 mm Hg
Boiling Point: 88.00 °C. @ 760.00 mm Hg
Vapor Pressure:67.302002 mm/Hg @ 25.00 °C. (est)
Vapor Density:3.6 ( Air = 1 )
Flash Point: 23.00 °F. TCC ( -5.00 °C. )
logP (o/w): 0.840
Soluble in:
 alcohol
 water, 70000 mg/L @ 18C (exp)
Similar Items:note
acrolein diethyl acetal
alpha-amyl cinnamaldehyde diethyl acetal
para-anisaldehyde diethyl acetal
benzaldehyde diethyl acetal
butyraldehyde diethyl acetal
isobutyraldehyde diethyl acetal
cinnamaldehyde diethyl acetal
citral diethyl acetal
citronellal diethyl acetal
citronellyl oxyacetaldehyde diethyl acetal
crotonaldehyde diethyl acetal
cyclamen aldehyde diethyl acetal
cyclohexanone diethyl acetal
decanal diethyl acetal
(Z)-4-decen-1-al diethyl acetal
dodecanal diethyl acetal
3-ethoxypropionaldehyde diethyl acetal
ethyl vanillin diethyl acetal
furfural diethyl acetal
heliotropyl diethyl acetal
heptanal diethyl acetal
(Z)-4-hepten-1-al diethyl acetal
hexanal diethyl acetal
(Z)-3-hexen-1-al diethyl acetal
(E)-2-hexen-1-al diethyl acetal
alpha-hexyl cinnamaldehyde diethyl acetal
hydroxycitronellal diethyl acetal
methional diethyl acetal
2-methyl butyraldehyde diethyl acetal
(E,Z)-2,6-nonadien-1-al diethyl acetal
nonanal diethyl acetal
isononanal diethyl acetal
octanal diethyl acetal
isooctanal diethyl acetal
phenyl acetaldehyde diethyl acetal
propionaldehyde diethyl acetal
tridecanal diethyl acetal
undecanal diethyl acetal
valeraldehyde diethyl acetal
isovaleraldehyde diethyl acetal
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Aceto
Diethoxy Methane
EMD Millipore
For experimental / research use only.
Formaldehyde Diethyl Acetal
Penta International
FORMALDEHYDE DIETHYL ACETAL
Santa Cruz Biotechnology
For experimental / research use only.
Diethoxymethane
Sigma-Aldrich
For experimental / research use only.
Diethoxymethane 99.7%, contains 50-150 ppm BHT as stabilizer
TCI AMERICA
For experimental / research use only.
Ethylal >99.0%(GC)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 11 - Highly flammable.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rabbit LD50 2600 mg/kg
(Knoefel et al., 1932)

oral-rabbit LD50 2604 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 29, Pg. 730, 1932.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: flavoring agents
Recommendation for formaldehyde diethyl acetal usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.097 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 1600 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 3.0000015.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 2.0000010.00000
Edible ices, including sherbet and sorbet (03.0): 3.0000015.00000
Processed fruit (04.1): 2.0000010.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 4.0000020.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 2.0000010.00000
Bakery wares (07.0): 5.0000025.00000
Meat and meat products, including poultry and game (08.0): 1.000005.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 1.000005.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 2.0000010.00000
Foodstuffs intended for particular nutritional uses (13.0): 3.0000015.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 2.0000010.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 4.0000020.00000
Ready-to-eat savouries (15.0): 5.0000025.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 2.0000010.00000
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 3 (FGE.03); Acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated aldehydes, and a orthoester of formic acid, from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 3, Revision 1 (FGE.03Rev1): Acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated or unsaturated aldehydes, an ester of a hemiacetal and an orthoester of formic acid, from chemical groups 1, 2 & 4 Commission Regulation (EC) No 1565/2000 of 18 July 2000) [1] - Scientific Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)on a request from the Commission
View page or View pdf

Flavouring Group Evaluation 61 (FGE.61): Consideration of aliphatic acyclic acetals evaluated by JECFA (57th meeting) structurally related to acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated aldehydes, and an orthoester of formic acid evaluated by EFSA in FGE.03 (2004) (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf

Flavouring Group Evaluation 61, Revision 1 (FGE.61Rev1): Consideration of aliphatic acetals evaluated by JECFA (57th meeting) structurally related to acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated aldehydes and one orthoester of formic acid evaluated
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 3, Revision 2 (FGE.03Rev2): Acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated or unsaturated aldehydes, an ester of a hemiacetal and an orthoester of formic acid, from chemical groups 1, 2 and 4
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):462-95-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10024
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 2373
WGK Germany:1
ethoxymethoxyethane
Chemidplus:0000462953
EPA/NOAA CAMEO:hazardous materials
RTECS:PA8500000 for cas# 462-95-3
 
References:
 ethoxymethoxyethane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:462-95-3
Pubchem (cid):10024
Pubchem (sid):134973496
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2911.00.5000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 plum fruit
Search Trop Picture
 rum - 0.8 mg/kg
Search PMC Picture
 
Synonyms:
 diethoxy methane
 diethoxymethane
1,1-diethoxymethane
 diethoxymethane [UN2373] [Flammable liquid]
 diethyl formal
 diethylformal
 ethane, 1,1'-(methylenebis(oxy))bis-
 ethane, 1,1'-[methylenebis(oxy)]bis-
(ethoxymethoxy)ethane
 ethoxymethoxyethane
 ethoxymethyl ethyl ether
 ethoxymethylethyl ether
 ethylal
 formaldehyde, diethyl acetal
 methane, diethoxy-
1,1'-(methylenebis(oxy))bisethane
 

Articles:

 None found yet.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy