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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 269.00 to 270.00 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 0.007000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 265.00 °F. TCC ( 129.20 °C. ) (est)
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| logP (o/w): | -0.246 (est) |
| Soluble in: |
| | alcohol |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Type: caramellic |
| caramellic |
| Odor Description:caramellic |
| Flavor Type: creamy |
| creamy bready bread crust |
| Taste Description: creamy bready |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for 6-acetyl-1,2,3,4-tetrahydropyridine usage levels up to: | | | not for fragrance use.
|
| |
Safety References:
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| No odor group found for these |
(R)- strawberry furanone
FL/FR |
(S)- strawberry furanone
FL/FR |
| acidic |
| acidic |
cyclohexyl acetic acid
FL/FR |
| balsamic |
2- acetyl furan
FL/FR |
iso amyl pyruvate
FL/FR |
| bready |
coffee furanone
FL/FR |
furfural
FL/FR |
| burnt |
rum ether
FL/FR |
| buttery |
acetoin
FL/FR |
acetyl butyryl
FL/FR |
acetyl propionyl
FL/FR |
3,4- hexane dione
FL/FR |
| caramellic |
iso amyl levulinate
FL/FR |
2-oxo butyric acid
FL/FR |
caramel furanone solution
FL/FR |
caramel pentadione
FL/FR |
cyclotene
FL/FR |
cyclotene hydrate
FL/FR |
alpha,alpha- dimethyl anisyl acetone
FL/FR |
ethyl 2-hydroxy-2-methyl butyrate
FL/FR |
ethyl cyclopentenolone
FL/FR |
ethyl furaneol
FL/FR |
ethyl maltol
FL/FR |
5- ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR |
3- ethyl-4-methyl cyclotene
FL/FR |
fenugreek absolute
FL/FR |
fenugreek oleoresin
FL/FR |
immortelle absolute
FL/FR |
levulinic acid
FL/FR |
maltol
FL/FR |
maltyl isobutyrate
FL/FR |
maltyl propionate
FL/FR |
maple furanone
FL/FR |
menthone lactone
FL/FR |
5- methyl furfural
FL/FR |
iso propenyl pyrazine
FL/FR |
rosefuran
FL/FR |
shoyu furanone
FL/FR |
strawberry furanone
FL/FR |
strawberry furanone acetate
FL/FR |
strawberry furanone solution
FL/FR |
toffee furanone
FL/FR |
| chocolate |
2,6- dimethyl pyrazine
FL/FR |
| cocoa |
2- methyl butyraldehyde
FL/FR |
| coconut |
gamma- heptalactone
FL/FR |
| creamy |
gamma- butyrolactone
FL/FR |
| ethereal |
ethyl 4-pentenoate
FL/FR |
ethyl pyruvate
FL/FR |
| fermented |
amyl alcohol
FL/FR |
butyl laevo-lactate
FL/FR |
ethyl (E)-2-crotonate
FL/FR |
ethyl crotonate
FL/FR |
valeraldehyde
FL/FR |
| floral |
phenethyl alcohol
FL/FR |
| fruity |
iso butyl 2-butenoate
FL/FR |
cherry propanol
FL/FR |
ethyl lactate
FL/FR |
(E)- ethyl tiglate
FL/FR |
hexyl (E)-tiglate
FL/FR |
maltyl acetate
FL/FR |
methyl nonane dione
FL/FR |
2- pentyl furan
FL/FR |
tetrahydrofurfuryl acetate
FL/FR |
| green |
iso amyl 3-(2-furan) propionate
FL/FR |
| herbal |
butyl levulinate
FL/FR |
white cognac oil
FL/FR |
| meaty |
sulfurol
FL/FR |
sulfuryl acetate
FL/FR |
| minty |
dextro- carvone
FL/FR |
| musty |
2- acetyl pyrrole
FL/FR |
3- acetyl-2,5-dimethyl furan
FL/FR |
| nutty |
2- acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR |
2- acetyl-5-methyl furan
FL/FR |
3,5- cocoa pyrazine
FL/FR |
1,2- cyclohexane dione
FL/FR |
2,3- dimethyl pyrazine
FL/FR |
filbert pyrazine
FL/FR |
2,6- lutidine
FL/FR |
2- methyl thio-3,5 or 6-methyl pyrazine
FL/FR |
nutty cyclohexenone
FL/FR |
| phenolic |
4- methyl-2,6-dimethoxyphenol
FL/FR |
| popcorn |
2- acetyl pyrazine
FL/FR |
2- acetyl pyridine
FL/FR |
| spicy |
caraway seed oleoresin
FL/FR |
(E)- propyl 2-furan acrylate
FL/FR |
spicy acetoacetate
FL/FR |
(E)- tiglic acid
FL/FR |
| sweet |
vanilla oleoresin bali
FL/FR |
| vanilla |
ethyl vanillin
FL/FR |
vanilla oleoresin bourbon
FL/FR |
vanillin
FL/FR |
vanillyl isobutyrate
FL/FR |
| vegetable |
tetrahydrofurfuryl alcohol
FL/FR |
| For Flavor |
| No flavor group found for these |
4- acetyl-2,5-dimethyl-3(2H)-furanone
FL |
2- acetyl-3,4,5,6-tetrahydropyridine
FL |
(E)- aconitic acid
FL |
allyl 2-furoate
FL |
iso amyl levulinate
FL/FR |
iso amyl pyruvate
FL/FR |
benzyl disulfide
FL |
1,2- cyclohexane dione
FL/FR |
2,5- diethyl tetrahydrofuran
FL |
alpha,alpha- dimethyl anisyl acetone
FL/FR |
ethyl 2-hydroxy-2-methyl butyrate
FL/FR |
ethyl 4-pentenoate
FL/FR |
5- ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one
FL/FR |
3- ethyl-4-methyl cyclotene
FL/FR |
furfuryl acetone
FL |
menthone lactone
FL/FR |
methyl nonane dione
FL/FR |
rosefuran
FL/FR |
(S)- strawberry furanone
FL/FR |
(R)- strawberry furanone
FL/FR |
strawberry furanone ethyl ether
FL |
|
iso amyl 3-(2-furan) propionate
FL/FR |
| acetic |
| acetic |
formic acid
FL |
| acidic |
levulinic acid
FL/FR |
dextro,laevo- tartaric acid
FL |
| berry |
maltyl acetate
FL/FR |
| bready |
bread crust distillate
FL |
mango furanone
FL |
2- propionyl thiazole
FL |
| brown |
2-oxo butyric acid
FL/FR |
fenugreek oleoresin
FL/FR |
furfural
FL/FR |
5- methyl furfural
FL/FR |
tetrahydrofurfuryl acetate
FL/FR |
(E)- tiglic acid
FL/FR |
| burnt |
furfuryl alcohol
FL |
iso propenyl pyrazine
FL/FR |
rum ether
FL/FR |
| buttery |
butyl laevo-lactate
FL/FR |
diacetyl
FL |
3,4- hexane dione
FL/FR |
| caramellic |
caramel dione
FL |
caramel furanone
FL |
caramel furanone solution
FL/FR |
caramel pentadione
FL/FR |
cyclotene
FL/FR |
cyclotene hydrate
FL/FR |
ethyl furaneol
FL/FR |
ethyl maltol
FL/FR |
5- ethyl-3,4,5,6-tetramethyl cyclohexen-2-one
FL |
fenugreek absolute
FL/FR |
maltol
FL/FR |
maltyl propionate
FL/FR |
maple furanone
FL/FR |
3- methyl butyl 2-furyl butyrate
FL |
pyruvaldehyde
FL |
shoyu furanone
FL/FR |
strawberry furanone
FL/FR |
strawberry furanone acetate
FL/FR |
strawberry furanone solution
FL/FR |
toffee furanone
FL/FR |
| cocoa |
butyraldehyde
FL |
| coffee |
coffee distillates
FL |
diisoamyl thiomalate
FL |
2- thiophene thiol
FL |
| corn |
2- acetyl pyridine
FL/FR |
2- acetyl-2-thiazoline
FL |
| creamy |
acetoin
FL/FR |
acetyl butyryl
FL/FR |
2- propanoyl thiophene
FL |
| fatty |
diacetyl trimer
FL |
2,4- undecadienal
FL |
(E,E)-2,4- undecadienal
FL |
| floral |
phenethyl alcohol
FL/FR |
rosa canina seed extract
FL |
| fruity |
cherry propanol
FL/FR |
ethyl lactate
FL/FR |
(E)- ethyl tiglate
FL/FR |
furfuryl valerate
FL |
2- pentanoyl furan
FL |
banana cream pie flavor
FL |
(E)- propyl 2-furan acrylate
FL/FR |
| fusel |
amyl alcohol
FL/FR |
white cognac oil
FL/FR |
2- methyl butyraldehyde
FL/FR |
| green |
iso butyl 2-butenoate
FL/FR |
hexyl (E)-tiglate
FL/FR |
immortelle absolute
FL/FR |
2- pentyl furan
FL/FR |
| herbal |
butyl levulinate
FL/FR |
5- hydroxymethyl furfural
FL |
| jammy |
ethyl cyclopentenolone
FL/FR |
maltyl isobutyrate
FL/FR |
| lactonic |
gamma- heptalactone
FL/FR |
| malty |
hordeum vulgare extract (cereal grass)
FL |
malt distillates
FL |
| meaty |
2,6- dimethyl pyrazine
FL/FR |
sulfurol
FL/FR |
sulfuryl acetate
FL/FR |
| metallic |
2,5- dihydroxy-1,4-dithiane
FL |
| milky |
gamma- butyrolactone
FL/FR |
| minty |
dextro- carvone
FL/FR |
| molasses |
molasses blackstrap
FL |
| musty |
ethyl (E)-2-crotonate
FL/FR |
| nutty |
2- acetyl furan
FL/FR |
2- acetyl pyrrole
FL/FR |
3- acetyl-2,5-dimethyl furan
FL/FR |
2- acetyl-3,5(or 6)-dimethyl pyrazine
FL/FR |
2- acetyl-5-methyl furan
FL/FR |
aconitic acid
FL |
3,5- cocoa pyrazine
FL/FR |
coffee furanone
FL/FR |
2,3- dimethyl pyrazine
FL/FR |
filbert pyrazine
FL/FR |
2,6- lutidine
FL/FR |
2- methyl thio-3,5 or 6-methyl pyrazine
FL/FR |
nutty cyclohexenone
FL/FR |
peanut oxazole
FL |
tetrahydrofurfuryl alcohol
FL/FR |
| phenolic |
4- methyl-2,6-dimethoxyphenol
FL/FR |
| roasted |
acer spicatum bark extract
FL |
2- acetyl pyrazine
FL/FR |
| rummy |
ethyl crotonate
FL/FR |
ethyl pyruvate
FL/FR |
| smoky |
dextro- xylose
FL |
| spicy |
caraway seed oleoresin
FL/FR |
spicy acetoacetate
FL/FR |
| sweet |
acetone alcohol
FL |
cyclohexyl acetic acid
FL/FR |
honey distillates
FL |
dextro- sorbitol
FL |
sugar distillates
FL |
vanilla oleoresin bali
FL/FR |
| toasted |
acetyl propionyl
FL/FR |
| vanilla |
ethyl vanillin
FL/FR |
vanilla oleoresin bourbon
FL/FR |
vanillin
FL/FR |
vanillyl isobutyrate
FL/FR |
| waxy |
furfuryl octanoate
FL |
octyl 2-furoate
FL |
| winey |
valeraldehyde
FL/FR |
| yeasty |
faex extracts
FL |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2- | acetyl-1,4,5,6-tetrahydropyridine | | | ethanone, 1-(1,4,5,6-tetrahydro-2-pyridinyl)- | | | pyridine, 2-acetyl-1,4,5,6-tetrahydro- | | 1-(1,4,5,6- | tetrahydro-2-pyridinyl) ethanone | | 1-(1,4,5,6- | tetrahydropyridin-2-yl)ethanone | | 1-(1,2,3,4- | tetrahydropyridin-6-yl)ethanone |
Articles:
| PubMed:New short and general synthesis of three key Maillard flavour compounds: 2-Acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine and 5-acetyl-2,3-dihydro-4H-1,4-thiazine. |
| PubMed:Stabilization of the potent odorant 2-acetyl-1-pyrroline and structural analogues by complexation with zinc halides. |
| PubMed:Chemistry of 2-acetyl-1-pyrroline, 6-acetyl-1,2,3,4-tetrahydropyridine, 2-acetyl-2-thiazoline, and 5-acetyl-2,3-dihydro-4H-thiazine: extraordinary Maillard flavor compounds. |
| PubMed:An expeditious, high-yielding construction of the food aroma compounds 6-acetyl-1,2,3,4-tetrahydropyridine and 2-acetyl-1-pyrroline. |
| PubMed:Elucidation of tautomer structures of 2-acetyltetrahydropyridine using gas chromatography/mass spectrometry and gas chromatography/infrared spectroscopy. |
| PubMed:Detailed investigation of the production of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine in proline/1,3-dihydroxyacetone model systems. |
| PubMed:Formation of odorants in Maillard model systems based on l-proline as affected by pH. |
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Responsible for mousy taint in wines. Constit. of wheat, popcorn and bread aroma
6-Acetyl-2,3,4,5-tetrahydropyridine is a substituted tetrahydropyridine and a cyclic imine as well as a ketone. The compound exists in a chemical equilibrium with its tautomer 6-acetyl-1,2,3,4-tetrahydropyridine that differs only by the position of the double bond in the tetrahydropyridine ring:; 6-Acetyl-2,3,4,5-tetrahydropyridine, with the IUPAC name 1-(3,4,5,6-tetrahydropyridin-2-yl)ethanone, is an aroma compound and flavor that gives baked goods such as white bread, pop corn, or tortillas their typical smell, together with its structural homolog 2-acetyl-1-pyrroline. Flavouring compound [Flavornet]
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3D/inchi