|
Category:flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 98.00 to 100.00
|
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 1.12000 to 1.13000 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 9.320 to 9.403
|
| Refractive Index: | 1.43000 to 1.44000 @ 20.00 °C.
|
| Melting Point: | -43.30 °C. @ 760.00 mm Hg
|
| Boiling Point: | 204.00 to 205.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.450000 mmHg @ 25.00 °C. |
| Vapor Density: | 3.00 ( Air = 1 ) |
| Flash Point: | 209.00 °F. TCC ( 98.33 °C. )
|
| logP (o/w): | -0.640 |
| Soluble in: |
| | alcohol | | | water, 1.00E+06 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor Type: creamy |
| creamy oily fatty caramellic |
| Odor Description:at 100.00 %. creamy oily fatty caramel |
| creamy oily fatty |
Odor Description:Creamy, oily with fatty nuances
Mosciano, Gerard P&F 16, No. 2, 49, (1991) |
| Flavor Type: milky |
| milky creamy fruity peach |
Taste Description: at 75.00 ppm. Milky, creamy with fruity peach-like afternotes
Mosciano, Gerard P&F 16, No. 2, 49, (1991) |
| Odor and/or flavor descriptions from others (if found). |
| Ernesto Ventós |
| BUTYROLACTONE GAMMA |
| Odor Description:SWEET, AROMATIC, CREAMY |
| Indukern F&F |
| GAMMA-BUTYROLACTONE |
| Odor Description:OILY, CREAMY, FATTY |
| Advanced Biotech |
| GAMMA-BUTYROLACTONE SYNTHETIC |
| Odor Description:Caramel, Fatty, Creamy |
| Prodasynth |
| GAMMA BUTYROLACTONE (> 98%) |
| Odor Description:SWEET, AROMATIC, CREAMY |
Cosmetic Information:
Suppliers:
| Augustus Oils |
| Gamma Butyrolactone
|
| Services |
| Beijing Lys Chemicals |
| gamma-Butyrolactone
|
| BOC Sciences |
| For experimental / research use only. |
| gamma-Butyrolactone
|
| Capot Chemical |
| gamma-Butyrolactone
|
| Covalent Chemical |
| gamma-Butyrolactone
|
| Diffusions Aromatiques |
| gamma-BUTYROLACTONE
|
| Ernesto Ventós |
| BUTYROLACTONE GAMMA
Odor: SWEET, AROMATIC, CREAMY |
| Indukern F&F |
| GAMMA-BUTYROLACTONE
Odor: OILY, CREAMY, FATTY |
| Inoue Perfumery |
| gamma-BUTYROLACTONE
|
| LyondellBasell Industries |
| gamma-Butyrolactone
|
| M&U International |
| gamma-BUTYROLACTONE, Kosher
|
| M&U International |
| NAT. gamma-BUTYROLACTONE
|
| Penta International |
| GAMMA-BUTYROLACTONE FCC
|
| Penta International |
| GAMMA-BUTYROLACTONE NATURAL
|
| Penta International |
| GAMMA-BUTYROLACTONE SYNTHETIC 10% IN PROPYLENE GLYCOL
|
| Penta International |
| gamma-BUTYROLACTONE
|
| Prodasynth |
| GAMMA BUTYROLACTONE
(> 98%) Odor: SWEET, AROMATIC, CREAMY |
| R C Treatt & Co Ltd |
| gamma-Butyrolactone
|
| Shiva Chemicals and Pharmaceuticals |
| Gamma Butrolactone
|
| Sigma-Aldrich |
| 4-Hydroxybutanoic acid lactone, ≥98%, FCC, FG
Odor: caramel |
| Certified Food Grade Products |
| Tengzhou Xiang Yuan Aroma Chemicals |
| gamma-Butyrolactone
|
| United International |
| Gamma Butyrolactone
|
| Vigon International |
| BUTYROLACTONE GAMMA
|
| WEN International |
| Gamma-BUTYROLACTONE, natural
|
| WholeChem |
| gamma-Butyrolactone
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed.
R 36 - Irritating to eyes.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/39 - Wear suitable clothing and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1540 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(1), Pg. 49, 1987.
gavage-mouse LD50 1245 mg/kg
(Schafer & Bowles, 1985)
intraperitoneal-rat LD50 1000 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
oral-mouse LD50 1460 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: GENERAL ANESTHETIC
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 64(2), Pg. 3, 1999.
intraperitoneal-mouse LD50 1100 mg/kg
BEHAVIORAL: GENERAL ANESTHETIC
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
parenteral-mouse LDLo 1600 mg/kg
"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 7, Pg. 687, 1955.
intravenous-rabbit LDLo 500 mg/kg
Archivum Immunologiae et Therapiae Experimentalis. Vol. 13, Pg. 70, 1965.
|
| Dermal Toxicity: |
skin-guinea pig LD50 > 5000 mg/kg
GAF Material Safety Data Sheet.
|
| Inhalation Toxicity: |
inhalation-rat LC50 > 5100 mg/m3/4H
National Technical Information Service. Vol. OTS0534527
|
Safety in Use Information:
| Category: | | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for gamma-butyrolactone usage levels up to: | | | 0.5000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 110.00 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 5 |
| Click here to view publication 5 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 20.00000 |
| beverages(nonalcoholic): | - | 10.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | 20.00000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 10.00000 |
| fruit ices: | - | 10.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | 10.00000 |
| hard candy: | - | 10.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 10.00000 |
| milk products: | - | 10.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 10.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
|
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
|
Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf
|
Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab)
View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009)
View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30
View page or View pdf
|
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):96-48-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :7302 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| oxolan-2-one |
| Chemidplus:0000096480 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:96-48-0 |
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| No odor group found for these |
iso valeraldehyde diethyl acetal
FL/FR |
| aldehydic |
| aldehydic |
acetyl nonyryl
FL/FR |
iso valeraldehyde
FL/FR |
| balsamic |
amyl cinnamate
FL/FR |
| buttery |
acetoin
FL/FR |
acetyl butyryl
FL/FR |
acetyl isobutyryl
FL/FR |
acetyl propionyl
FL/FR |
butyl butyryl lactate
FL/FR |
| caramellic |
2-oxo butyric acid
FL/FR |
strawberry furanone acetate
FL/FR |
| cheesy |
butyric acid
FL/FR |
2- methyl hexanoic acid
FL/FR |
| coconut |
coconut decanone methyl
FR |
delta- decalactone
FL/FR |
delta-2- dodecenolactone
FL/FR |
delta- nonalactone
FL/FR |
gamma- octalactone
FL/FR |
delta- undecalactone
FL/FR |
| coffee |
furfuryl mercaptan
FL/FR |
| creamy |
creamy lactone
FL/FR |
3- heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR |
para- vanillic acid
FL/FR |
para- vanillyl alcohol
FL/FR |
| earthy |
1- nonen-3-ol
FL/FR |
| ethereal |
decyl propionate
FL/FR |
| fatty |
allyl cyclohexyl hexanoate
FL/FR |
allyl decanoate
FL/FR |
butter esters
FL/FR |
iso butyl undecylenate
FL/FR |
coconut absolute
FL/FR |
(Z)- dairy lactone
FL/FR |
(R)-gamma- decalactone
FL/FR |
(S)-gamma- decalactone
FL/FR |
dodecyl butyrate
FL/FR |
(Z)- ethyl oleate
FL/FR |
ethyl undecylenate
FL/FR |
4- methyl octanoic acid
FL/FR |
(Z)-3- octen-1-ol
FL/FR |
perilla seed oil
FL/FR |
sorbitan oleate
CS |
(E,Z,Z)-2,4,7- tridecatrienal
FL/FR |
| fermented |
butyl laevo-lactate
FL/FR |
| floral |
citronellyl formate
FL/FR |
geraniol
FL/FR |
jasmin pyranone
FL/FR |
para- methyl acetophenone
FL/FR |
octanal / methyl anthranilate schiff's base
FR |
2- pentadecanone
FL/FR |
| fruity |
acetoin acetate
FL/FR |
allyl cyclohexyl butyrate
FL/FR |
bitter almond oil
FL/FR |
iso amyl 2-methyl butyrate
FL/FR |
butyl 2-decenoate
FL/FR |
cyclohexyl cinnamate
FL/FR |
gamma- decalactone
FL/FR |
(S)-delta- decalactone
FL/FR |
(S)-gamma- dodecalactone
FL/FR |
epsilon- dodecalactone
FL/FR |
dodecyl isobutyrate
FL/FR |
ethyl 5-hydroxyoctanoate
FL/FR |
ethyl lactate
FL/FR |
farnesyl acetone
FL/FR |
(R)-(-)-2- heptanol
FL/FR |
(E)-2- hepten-1-yl acetate
FL/FR |
mango peach fragrance
FR |
methyl (Z)-5-octenoate
FL/FR |
methyl 3-nonenoate
FL/FR |
octyl heptanoate
FL/FR |
peach cyclopentanone
FR |
peach pivalate
FR |
3- phenyl propyl hexanoate
FL/FR |
plum crotonate
FR |
gamma- undecalactone (aldehyde C-14 (so-called))
FL/FR |
2- undecanone
FL/FR |
vanilla carboxylate
FL/FR |
| green |
iso butyl benzyl carbinol
FL/FR |
butyl lactate
FL/FR |
3- heptanone
FL/FR |
(Z)-4- hepten-1-ol
FL/FR |
(Z)-3- hepten-1-ol
FL/FR |
(Z)-4- heptenal
FL/FR |
(Z)-4- heptenal diethyl acetal
FL/FR |
ivy dioxolane
FR |
neryl butyrate
FL/FR |
| herbal |
benzyl octanoate
FL/FR |
| mushroom |
(S)-(+)-2- heptanol
FL/FR |
3- octen-2-ol
FL/FR |
| oily |
amyl laurate
FL/FR |
butter acids
FL/FR |
petal pyranone
FL/FR |
| soapy |
ethyl undecanoate
FL/FR |
| sulfurous |
O- methyl S-1-methoxyhexan-3-yl carbonothioate
FL/FR |
| sweet |
vanilla oleoresin bali
FL/FR |
| tonka |
6- amyl-alpha-pyrone
FL/FR |
mint lactone
FL/FR |
| tropical |
delta- dodecalactone
FL/FR |
glyceryl 5-hydroxydodecanoate
FL/FR |
| vanilla |
ortho- dimethyl hydroquinone
FL/FR |
ethyl vanillin
FL/FR |
ethyl vanillin isobutyrate
FL/FR |
ethyl vanillin propylene glycol acetal
FL/FR |
vanillin
FL/FR |
vanillyl acetate
FL/FR |
vanillyl isobutyrate
FL/FR |
vanillylidene acetone
FL/FR |
| vegetable |
methional
FL/FR |
| waxy |
allyl nonanoate
FL/FR |
iso amyl decanoate
FL/FR |
(Z)-4- decen-1-ol
FL/FR |
9- decenoic acid
FL/FR |
ethyl palmitate
FL/FR |
heptyl octanoate
FL/FR |
2- methyl heptanoic acid
FL/FR |
methyl laurate
FL/FR |
methyl undecanoate
FR |
2- nonanol
FL/FR |
octyl 2-methyl butyrate
FL/FR |
octyl isobutyrate
FL/FR |
phenethyl octanoate
FL/FR |
propyl decanoate
FL/FR |
delta- tetradecalactone
FL/FR |
2- tridecanone
FL/FR |
undecanoic acid
FL/FR |
| winey |
2- hexanol
FL/FR |
| woody |
nopyl aldehyde
FR |
| For Flavor |
| No flavor group found for these |
allyl cyclohexyl butyrate
FL/FR |
allyl cyclohexyl hexanoate
FL/FR |
allyl methyl trisulfide
FL |
amyl laurate
FL/FR |
benzyl octanoate
FL/FR |
2- butyl thiophene
FL |
iso butyl undecylenate
FL/FR |
cocos nucifera water
FL |
(S)-delta- decalactone
FL/FR |
(S)-gamma- decalactone
FL/FR |
(R)-gamma- decalactone
FL/FR |
(Z)-4- decen-1-ol
FL/FR |
6- decenoic acid
FL |
decyl propionate
FL/FR |
ortho- dimethyl hydroquinone
FL/FR |
(S)-gamma- dodecalactone
FL/FR |
epsilon- dodecalactone
FL/FR |
delta-2- dodecenolactone
FL/FR |
dodecyl butyrate
FL/FR |
dodecyl isobutyrate
FL/FR |
2,3- epoxyoctanal
FL |
ethyl 5-hydroxyoctanoate
FL/FR |
farnesyl acetone
FL/FR |
(R)-(-)-2- heptanol
FL/FR |
(S)-(+)-2- heptanol
FL/FR |
(Z)-3- hepten-1-ol
FL/FR |
(E)-2- hepten-1-yl acetate
FL/FR |
2- hexanol
FL/FR |
3- methyl-2-cyclopenten-1-one
FL |
4- methyl-2-pentenoic acid
FL |
3,5- octadien-2-one
FL |
octyl heptanoate
FL/FR |
oenanthic ether
FL |
perilla seed oil
FL/FR |
propyl decanoate
FL/FR |
valeraldehyde diethyl acetal
FL |
iso valeraldehyde diethyl acetal
FL/FR |
| acidic |
| acidic |
(E)-2- hexenoic acid
FL |
| aldehydic |
acetyl nonyryl
FL/FR |
| amber |
iso butyl benzyl carbinol
FL/FR |
| balsamic |
amyl cinnamate
FL/FR |
vanillylidene acetone
FL/FR |
| bitter |
(E,Z,Z)-2,4,7- tridecatrienal
FL/FR |
| brown |
2-oxo butyric acid
FL/FR |
| buttery |
butyl laevo-lactate
FL/FR |
diacetyl
FL |
| cabbage |
methyl 2-thiofuroate
FL |
| caramellic |
strawberry furanone acetate
FL/FR |
| coconut |
delta- decalactone
FL/FR |
(R)- massoia lactone
FL |
6- methyl coumarin
FL |
| coffee |
furfuryl mercaptan
FL/FR |
| creamy |
acetoin
FL/FR |
acetyl butyryl
FL/FR |
acetyl isobutyryl
FL/FR |
6- amyl-alpha-pyrone
FL/FR |
butter esters
FL/FR |
butyl butyryl lactate
FL/FR |
creamy lactone
FL/FR |
divanillin
FL |
delta- dodecalactone
FL/FR |
glyceryl 5-hydroxydodecanoate
FL/FR |
jasmin pyranone
FL/FR |
para- methyl acetophenone
FL/FR |
mint lactone
FL/FR |
delta- nonalactone
FL/FR |
octyl isobutyrate
FL/FR |
delta- undecalactone
FL/FR |
gamma- undecalactone (aldehyde C-14 (so-called))
FL/FR |
para- vanillic acid
FL/FR |
para- vanillyl alcohol
FL/FR |
| dairy |
methyl (Z)-5-octenoate
FL/FR |
| earthy |
1- nonen-3-ol
FL/FR |
| fatty |
butter acids
FL/FR |
coconut absolute
FL/FR |
(Z)- dairy lactone
FL/FR |
dimethyl sulfoxide
FL |
(Z)- ethyl oleate
FL/FR |
ethyl undecylenate
FL/FR |
4- methyl octanoic acid
FL/FR |
2,4- octadien-1-ol
FL |
(Z)-3- octen-1-ol
FL/FR |
2- pentadecanone
FL/FR |
2- pentyl thiophene
FL |
2- tridecanone
FL/FR |
2,4- undecadienal
FL |
| floral |
geraniol
FL/FR |
| fruity |
acerola peach flavor
FL |
acetoin acetate
FL/FR |
acetyl isovaleryl
FL |
allyl decanoate
FL/FR |
bitter almond oil
FL/FR |
iso amyl 2-methyl butyrate
FL/FR |
butyl 2-decenoate
FL/FR |
citronellyl formate
FL/FR |
cyclohexyl cinnamate
FL/FR |
gamma- decalactone
FL/FR |
(E)-2- decenoic acid
FL |
ethyl lactate
FL/FR |
garcinia mangostana fruit extract
FL |
3- heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR |
2- hexyl-4-acetoxytetrahydrofuran
FL |
methyl (E)-3-nonenoate
FL |
methyl 3-nonenoate
FL/FR |
phenethyl octanoate
FL/FR |
3- phenyl propyl hexanoate
FL/FR |
iso valeraldehyde
FL/FR |
vanilla carboxylate
FL/FR |
| green |
butyl lactate
FL/FR |
heptanal 2,3-butane diol acetal
FL |
(Z)-4- hepten-1-ol
FL/FR |
(Z)-4- heptenal
FL/FR |
(E)-2- heptenal
FL |
(Z)-4- heptenal diethyl acetal
FL/FR |
3-(5- methyl-2-furyl) butanal
FL |
neryl butyrate
FL/FR |
2,4- octadienal
FL |
| ketonic |
3- heptanone
FL/FR |
| lactonic |
gamma- octalactone
FL/FR |
| milky |
dextro,laevo-3-( methyl thio) butanone
FL |
| mushroom |
3- octen-2-ol
FL/FR |
| nutty |
arachis hypogaea fruit extract
FL |
| oily |
2- methyl hexanoic acid
FL/FR |
petal pyranone
FL/FR |
| powdery |
powdery ketone
FL |
| roasted |
O- methyl S-1-methoxyhexan-3-yl carbonothioate
FL/FR |
| sour |
butyric acid
FL/FR |
| spicy |
benzylidene acetone
FL |
| sweet |
vanilla oleoresin bali
FL/FR |
| toasted |
acetyl propionyl
FL/FR |
| tomato |
methional
FL/FR |
| vanilla |
ethyl vanillin
FL/FR |
ethyl vanillin isobutyrate
FL/FR |
ethyl vanillin propylene glycol acetal
FL/FR |
vanillin
FL/FR |
vanillyl acetate
FL/FR |
vanillyl isobutyrate
FL/FR |
| waxy |
allyl nonanoate
FL/FR |
iso amyl decanoate
FL/FR |
9- decenoic acid
FL/FR |
ethyl palmitate
FL/FR |
ethyl undecanoate
FL/FR |
furfuryl octanoate
FL |
heptyl octanoate
FL/FR |
2- methyl heptanoic acid
FL/FR |
methyl laurate
FL/FR |
2- nonanol
FL/FR |
octyl 2-furoate
FL |
octyl 2-methyl butyrate
FL/FR |
delta- tetradecalactone
FL/FR |
undecanoic acid
FL/FR |
2- undecanone
FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | agrisynth BLO | | 1,2- | butanolide | | 1,4- | butanolide | | 4- | butanolide | | | butyro-1,4-lactone | | 1,4- | butyrolactone | | 4- | butyrolactone | | g- | butyrolactone | | | butyrolactone gamma | | gamma- | butyrolactone natural | | | butyryl lactone | | 4- | deoxytetronic acid | | | dihydro-2(3H)-furanone | | 4,5- | dihydro-2(3H)-furanone | | | dihydrofuran-2(3H)-one | | | furan-2(3H)-one, dihydro- | | 2(3H)- | furanone, dihydro- | | 4- | hydroxy-butanoic acid g-lactone | | 4- | hydroxybutanoic acid lactone | | gamma- | hydroxybutyric acid cyclic ester | | 4- | hydroxybutyric acid lactone | | g- | hydroxybutyric acid lactone | | gamma- | hydroxybutyric acid lactone | | gamma- | hydroxybutyrolactone | | | oxolan-2-one | | 2- | oxolanone | | | tetrahydro-2-furanone | | 2,3,4,5- | tetrahydro-2-furanone |
Articles:
| PubMed:Chemical composition and aroma evaluation of essential oils from Evolvulus alsinoides L. |
| PubMed:Catabolic pathway of gamma-caprolactone in the biocontrol agent Rhodococcus erythropolis. |
| PubMed:Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans. |
| PubMed:Inverse gas chromatographic evaluation of the influence of soy protein on the binding of selected butter flavor compounds in a wheat soda cracker system. |
| PubMed:Nine new and five known polyketides derived from a deep sea-sourced Aspergillus sp. 16-02-1. |
| PubMed:Determination of lactones in wines by headspace solid-phase microextraction and gas chromatography coupled with mass spectrometry. |
| PubMed:Chemical composition and aroma evaluation of essential oils from Evolvulus alsinoides L. |
| PubMed:Streptogramins - two are better than one! |
| PubMed:Accelerated aging against conventional storage: effects on the volatile composition of chardonnay white wines. |
| PubMed:Impact of perceptive interactions on red wine fruity aroma. |
| PubMed:Comparative study of equimolar doses of gamma-hydroxybutyrate (GHB), 1,4-butanediol (1,4-BD) and gamma-butyrolactone (GBL) on catalepsy after acute and chronic administration. |
| PubMed:Rapid and facile detection of four date rape drugs in different beverages utilizing proton transfer reaction mass spectrometry (PTR-MS). |
| PubMed:Catabolic pathway of gamma-caprolactone in the biocontrol agent Rhodococcus erythropolis. |
| PubMed:The discriminative stimulus effects of midazolam are resistant to modulation by morphine, amphetamine, dizocilpine, and γ-butyrolactone in rhesus monkeys. |
| PubMed:Use of microfungi in the treatment of oak chips: possible effects on wine. |
| PubMed:Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans. |
| PubMed:Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348). |
| PubMed:Enzymology of the polyenes pimaricin and candicidin biosynthesis. |
| PubMed:Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons. |
| PubMed:Production of fermentation aroma compounds by Saccharomyces cerevisiae wine yeasts: effects of yeast assimilable nitrogen on two model strains. |
| PubMed:Characterization of the most odor-active volatiles of orange wine made from a Turkish cv. Kozan (Citrus sinensis L. Osbeck). |
| PubMed:In vivo functions of the gamma-butyrolactone autoregulator receptor in Streptomyces ambofaciens producing spiramycin. |
| PubMed:Influence of wine turbidity on the accumulation of volatile compounds from the oak barrel. |
| PubMed:Inverse gas chromatographic evaluation of the influence of soy protein on the binding of selected butter flavor compounds in a wheat soda cracker system. |
| PubMed:GHB free acid: II. Isolation and spectroscopic characterization for forensic analysis. |
| PubMed:Changes in the concentration of yeast-derived volatile compounds of red wine during malolactic fermentation with four commercial starter cultures of Oenococcus oeni. |
| PubMed:Cloning and in vivo functional analysis by disruption of a gene encoding the gamma-butyrolactone autoregulator receptor from Streptomyces natalensis. |
| PubMed:Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats. |
| PubMed:Off-vine grape drying effect on volatile compounds and aromatic series in must from Pedro Ximénez grape variety. |
| PubMed:Influence of reinforcer type and route of administration on gamma-hydroxybutyrate discrimination in rats. |
| PubMed:Effects of gamma-hydroxybutyrate (GHB) on schedule-controlled responding in rats: role of GHB and GABAB receptors. |
| PubMed:The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies. |
| PubMed:C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. |
| PubMed:Volatile compounds emitted by sclerotia of Sclerotinia minor, Sclerotinia sclerotiorum, and Sclerotium rolfsii. |
| PubMed:Evolution of the aroma profile of sherry wine vinegars during an experimental aging in wood. |
| PubMed:Varietal differentiation of red wines in the Valencian region (Spain). |
| PubMed:Gamma-hydroxybutyrate, gamma-butyrolactone, and 1,4-butanediol: a case report and review of the literature. |
| PubMed:Antioxidant properties of aroma compounds isolated from soybeans and mung beans. |
| PubMed:Volatile compounds produced from monosodium glutamate in common food cooking. |
| PubMed:Coma and respiratory depression following the ingestion of GHB and its precursors: three cases. |
| PubMed:Direct release of the allergen tulipalin A from Alstroemeria cut flowers: a possible source of airborne contact dermatitis? |
| PubMed:Isolation and quantification of tuliposides and tulipalins in tulips (Tulipa) by high-performance liquid chromatography. |
| PubMed:Adverse events associated with ingestion of gamma-butyrolactone--Minnesota, New Mexico, and Texas, 1998-1999. |
| PubMed:Endogenous digoxin-like activity of mammalian-lignans and their derivatives. |
| PubMed:Gamma-butyrolactone's discriminability and effect on low rates of lever pressing by rats: alone and in combination with D-amphetamine and naloxone. |
| PubMed:Native American food and medicinal plants. 3. alpha-Methylene butyrolactone from Erythronium grandiflorum Pursh. |
| PubMed:Absorption of gamma-butyrolactone-gamma-carbonyl-L-histidyl-L-prolinamide citrate (DN-1417), an analog of thyrotropin-releasing hormone, in rats and dogs. |
| PubMed:[Anaphylactic shock to celery and sensitization to ragweed and mugwort. Crossed or concomitant allergy?]. |
| PubMed:Dopamine analog-induced hyperglycemia in rats: involvement of the adrenal medulla and the endocrine pancreas. |
| PubMed:Gamma-butyrolactone increases the rate of punished lever pressing by rats. |
| PubMed:The effect of chronic ethanol administration on central neurotransmitter mechanisms. |
| PubMed:[The cancerogenic activity of gamma-butyrolactone in mice]. |
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one of the furans with a carbonyl thereby forming a cyclic lactone. it is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. it is also used as a pharmacological agent and solvent. Present in morello cherry, melon, pineapple, blackberry, quince, strawberry jam, wine, soybeans, black tea, Bourbon vanilla, wheat bread, crispbread and other breads. Flavour ingredient [DFC]
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3D/inchi