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Fragrance Demo Formulas
CAS Number: 11028-42-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:234-257-7
XlogP3-AA:5.00 (est)
Molecular Weight:204.35628000
Formula:C15 H24
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Appearance:pale yellow to yellow liquid to solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 262.50 °C. @ 760.00 mm Hg
Boiling Point: 262.00 to 264.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.017000 mmHg @ 25.00 °C. (est)
Flash Point: 230.00 °F. TCC ( 110.00 °C. )
logP (o/w): 6.226 (est)
Soluble in:
 water, 0.1504 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor Type: woody
cedarwood woody
Odor Description:at 100.00 %. cedarwood woody
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: perfuming agents
Foreverest Resources
Cedrene 60%
Odor: characteristic
Use: The Cedrene is a natural compound which is extracted from Cunninghamia. Contents of alpha-Cedrene at 60% min.Has cedar woody and appeared light yellow transparent liquid.
R C Treatt & Co Ltd
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Dermal sensitization
 View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
Category 1: Products applied to the lips
0.27 %
Category 2: Products applied to the axillae
0.080 %
Category 3: Products applied to the face/body using fingertips
1.60 %
Category 4: Products related to fine fragrance
1.50 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.38 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.38 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.38 %
Category 5D: Baby Creams, baby Oils and baby talc
0.38 %
Category 6: Products with oral and lip exposure
0.88 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
3.10 %
Category 7B: Leave-on products applied to the hair with some hand contact
3.10 %
Category 8: Products with significant anogenital exposure
0.16 %
Category 9: Products with body and hand exposure, primarily rinse off
2.90 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
11.00 %
Category 10B: Household aerosol/spray products
11.00 %
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
5.80 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
5.80 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice ( For more details see chapter 1 of the Guidance for the use of IFRA Standards.

Recommendation for cedrene flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):11028-42-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :3080674
National Institute of Allergy and Infectious Diseases:Data
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:11028-42-5
Pubchem (cid):3080674
Pubchem (sid):135227648
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
For Odor
amber decane
cedar forest fragrance
hemlock western oil (tsuga heterophylla) canada
ionyl ethyl ether
myrtenyl acetate
tricyclo(,6)dec-3-enyl acetate
vetiveryl propionate
anona squamosa leaf oil
machilus kusanoi leaf oil
amber decatriene
ambrene acetal
amyris acetate
caryophyllene alcohol acetate
cedar cyclododecatriene
cedarwood oil alcohols
cedarwood oil himalaya
cedarwood oil terpenes
cedarwood oil texas
cedarwood oil virginia
cedarwood oil white
cedrela wood oil
cedrenyl acetate
cedryl acetate
dimethyl bicyclo(2.2.1)hept-2-yl)-2-oxabicyclo(2.2.2)octane
juniperus deppeana wood oil
juniperus mexicana extract
methyl cedryl ketone replacer
sandal pentanol
sugi wood oil
violet propanol
woody acetate
woody dodecane
For Flavor
No flavor group found for these
cedarwood oil alcohols
cedarwood oil terpenes
cedryl acetate
myrtenyl acetate
Potential Uses:
None Found
Occurrence (nature, food, other):note
 cedarwood oils
Search PMC Picture


PubMed:Effect of gibberellic acid (GA), indole acetic acid (IAA) and benzylaminopurine (BAP) on the synthesis of essential oils and the isomerization of methyl chavicol and trans-anethole in Ocimum gratissimum L.
PubMed:Role of sterically demanding chiral dirhodium catalysts in site-selective C-H functionalization of activated primary C-H bonds.
PubMed:Essential oils and crude extracts from Chrysanthemum trifurcatum leaves, stems and roots: chemical composition and antibacterial activity.
PubMed:Sesquiterpene acids from Shellac and their bioactivities evaluation.
PubMed:Interspecific competition between Microcystis aeruginosa and Anabaena flos-aquae from Taihu Lake, China.
PubMed:Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase.
PubMed:A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients. RIFM Expert Panel.
PubMed:Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
PubMed:Identification of volatile compounds emitted by Artemisia ordosica (Artemisia, Asteraceae) and changes due to mechanical damage and weevil infestation.
PubMed:GC-MS/MS method for the quantification of α-cedrene in rat plasma and its pharmacokinetic application.
PubMed:Fragrance material review on acetyl cedrene.
PubMed:Identification of insecticidal constituents of the essential oil of Acorus calamus rhizomes against Liposcelis bostrychophila Badonnel.
PubMed:Comparative study of the volatiles' composition of healthy and larvae-infested Artemisia ordosica.
PubMed:Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells.
PubMed:Composition, anticancer, and antimicrobial activities in vitro of the heartwood essential oil of Cunninghamia lanceolata var. konishii from Taiwan.
PubMed:Pyrolytic formation of polycyclic aromatic hydrocarbons from sesquiterpenes.
PubMed:Occurrences and potential risks of 16 fragrances in five German sewage treatment plants and their receiving waters.
PubMed:Fate and effects of acetyl cedrene in sediments inhabited by different densities of the deposit feeder, Capitella teleta.
PubMed:Phytochemical analysis of the essential oils of 10 endemic Cephalaria species from Turkey.
PubMed:Chemical composition, antimicrobial and antitumor activities of the essential oils and crude extracts of Euphorbia macrorrhiza.
PubMed:Essential oil composition and antibacterial activity of Monticalia greenmaniana (Asteraceae).
PubMed:Determination of gas-phase ozonolysis rate coefficients of a number of sesquiterpenes at elevated temperatures using the relative rate method.
PubMed:Degradation of terpenes and terpenoids from Mediterranean rangelands by mixed rumen bacteria in vitro.
PubMed:Essential oils of Cupressus funebris, Juniperus communis, and J. chinensis (Cupressaceae) as repellents against ticks (Acari: Ixodidae) and mosquitoes (Diptera: Culicidae) and as toxicants against mosquitoes.
PubMed:Chemical composition and antioxidant activity of essential oil from berries of Schisandra chinensis (Turcz.) Baill.
PubMed:Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed:Acaricidal activity against Tetranychus urticae and essential oil composition of four Croton species from Caatinga biome in northeastern Brazil.
PubMed:Biosynthesis of sesquiterpenes by the fungus Fusarium verticillioides.
PubMed:Chemical composition of the essential oil of Croton gossypiifolius from Venezuela.
PubMed:Persistency assessment and aerobic biodegradation of selected cyclic sesquiterpenes present in essential oils.
PubMed:An oxidative dearomatization-induced [5 + 2] cascade enabling the syntheses of α-cedrene, α-pipitzol, and sec-cedrenol.
PubMed:Antinociceptive effect of 7-hydroxy-3,4-dihydrocadalin isolated from Heterotheca inuloides: role of peripheral 5-HT₁ serotonergic receptors.
PubMed:Comparative analysis of essential oils of six Anthemis taxa from Serbia and Montenegro.
PubMed:Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents.
PubMed:Investigation of the fate and effects of acetyl cedrene on Capitella teleta and sediment bacterial community.
PubMed:Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate.
PubMed:[Studies on the chemical constituents of Coleus forskohlii].
PubMed:[Electroantennogram responses of Maruca testulalis (Lepidoptera: Pyralidae) to plant volatiles and sex pheromone].
PubMed:Consequences of conformational preorganization in sesquiterpene biosynthesis: theoretical studies on the formation of the bisabolene, curcumene, acoradiene, zizaene, cedrene, duprezianene, and sesquithuriferol sesquiterpenes.
PubMed:Chemical compositions and antioxidant/antimicrobial activities of various samples prepared from Schinus terebinthifolius leaves cultivated in Egypt.
PubMed:[Analysis of essential oil from different organs of Caryopteris tangutica].
PubMed:Identification of organic hydroperoxides and hydroperoxy acids in secondary organic aerosol formed during the ozonolysis of different monoterpenes and sesquiterpenes by on-line analysis using atmospheric pressure chemical ionization ion trap mass spectrometry.
PubMed:Flowerhead volatile oil composition of soilless culture-grown Chrysanthemum balsamita L.
PubMed:A gold-catalyzed entry into the sesquisabinene and sesquithujene families of terpenoids and formal total syntheses of cedrene and cedrol.
PubMed:Essential Oil Composition and Antibacterial Studies of Vitex negundo Linn. Extracts.
PubMed:Contribution to the analysis of the essential oil of Helichrysum italicum (Roth) G. Don. Determination of ester bonded acids and phenols.
PubMed:Antimicrobial activity of extractable conifer heartwood compounds toward Phytophthora ramorum.
PubMed:[Headspace solid-phase microextraction-gas chromatography-mass spectrometry for analysis of volatile components from Atractlodes macrocephala Koidz].
PubMed:Remote position substituents as modulators of conformational and reactive properties of quinones. Relevance of the pi/pi intramolecular interaction.
PubMed:From alpha-cedrene to crinipellin B and onward: 25 years of the alkene-arene meta-photocycloaddition reaction in natural product synthesis.
PubMed:New woody and ambery notes from cedarwood and turpentine oil.
PubMed:Evaluation of the developmental toxicity of acetyl cedrene.
PubMed:Changes in terpene content in milk from pasture-fed cows.
PubMed:Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences.
PubMed:Determination of fragrances at ng/L levels using CLSA and GC/MS detection.
PubMed:Aroma evaluation of an aquatic herb, Changpo (Acorus calamus Var. angustatus Bess), by AEDA and SPME.
PubMed:Determination of musks and other fragrance compounds at ng/L levels using CLSA (closed loop stripping analysis) and GC/MS detection.
PubMed:Orientation and feeding responses of the pollen beetle, Meligethes aeneus, to candytuft, Iberis amara.
PubMed:Pressurized fluids for extraction of cedarwood oil from Juniperus virginianna.
PubMed:Dissipation of fragrance materials in sludge-amended soils.
PubMed:Volatile sesquiterpene hydrocarbons characteristic for Penicillium roqueforti strains producing PR toxin.
PubMed:Effects of storage conditions on the composition of Citrus tamurana Hort. ex Tanaka (hyuganatsu) essential oil.
PubMed:Atmospheric lifetimes and fates of selected fragrance materials and volatile model compounds.
PubMed:Efficacy of vetiver oil and nootkatone as soil barriers against Formosan subterranean termite (Isoptera: Rhinotermitidae).
PubMed:Antimicrobial activity of some Pacific Northwest woods against anaerobic bacteria and yeast.
PubMed:Key tricyclic synthetic intermediates for the preparation of the sesquiterpenes alpha- and beta-cedrene.
PubMed:Formal total synthesis of (+/-)-alpha- and beta-cedrene by preparation of cedrone. Construction of the tricyclic carbon skeleton by the use of a highly efficient intramolecular Khand annulation.
PubMed:Selective oviposition by Aedes aegypti (Diptera: culicidae) in response to Mesocyclops longisetus (Copepoda: Cyclopoidea) under laboratory and field conditions.
PubMed:Potential antitermite compounds from Juniperus procera extracts.
PubMed:Cloning, expression, and characterization of epi-cedrol synthase, a sesquiterpene cyclase from Artemisia annua L.
PubMed:Analysis of the essential oil of Juniperus procera Endl. growing in Kenya.
PubMed:Allergic contact dermatitis from the synthetic fragrances Lyral and acetyl cedrene in separate underarm deodorant preparations.
PubMed:Novel Allylic Oxidation of alpha-Cedrene to sec-Cedrenol by a Rhodococcus Strain.
PubMed:The Essential Oil of Perilla ocimoides: A Rich Source of Rosefuran.
PubMed:Changes in pulmonary adenosine triphosphate-binding proteins detected by nucleotide photoaffinity labeling following treatment of mice with the tumor-modulatory agent butylated hydroxytoluene.
PubMed:Decrease in the protein kinase C-catalyzed phosphorylation of an endogenous lung protein (Mr 36,000) following treatment of mice with the tumor-modulatory agent butylated hydroxytoluene.
PubMed:Pharmacologic and genetic studies on the modulatory effects of butylated hydroxytoluene on mouse lung adenoma formation.
PubMed:Modulation of the incidence of urethane induced mouse lung adenomas by butylated hydroxytoluene (BHT).
PubMed:Considerations in the selection and use of chemicals within the animal facility.
PubMed:Exposure to an environment containing the aromatic red cedar, Juniperus virginiana: procarcinogenic, enzyme-inducing and insecticidal effects.
PubMed:Effect of different routes of administration of cedrene on hepatic drug metabolism.
major constituent of cedarwood oil.
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