EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dimenthyl glutarate
bis[5-methyl-2-(propan-2-yl)cyclohexyl] pentanedioate

Supplier Sponsors

Name:bis[5-methyl-2-(propan-2-yl)cyclohexyl] pentanedioate
CAS Number: 406179-71-3Picture of molecule3D/inchi
Nikkaji Web:J1.977.318C
XlogP3-AA:7.20 (est)
Molecular Weight:408.62248000
Formula:C25 H44 O4
NMR Predictor:Predict (works with chrome or firefox)
EFSA/JECFA Comments:
According to EFFA: Menthyl moiety mixture of the two racematic forms (1S,2R,5S) and (1R,2S,5R ), which is specified by the name. Since there are two menthyl moieties, three combinations exist, approximately 25 % +/+ 25 % - /- and 50 % +/-. (EFFA,2010a).
Category:flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:2250 dimenthyl glutarate
DG SANTE Food Flavourings:09.935 dimenthyl glutarate
FEMA Number:4604 dimenthyl glutarate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):406179-71-3 ; DIMENTHYL GLUTARATE
 
Physical Properties:
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 48.00 to 50.00 °C. @ 760.00 mm Hg
Boiling Point: 463.00 to 464.00 °C. @ 760.00 mm Hg (est)
Flash Point: 422.00 °F. TCC ( 216.70 °C. ) (est)
logP (o/w): 8.465 (est)
Soluble in:
 alcohol
 water, 6.492e-005 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Flavor Type: cooling
cooling
Taste Description: cooling
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavoring agents
Recommendation for dimenthyl glutarate usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 30.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 38000 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 20.0000050.00000
beverages(alcoholic): 20.0000060.00000
breakfast cereal: --
cheese: --
chewing gum: 600.000001600.00000
condiments / relishes: --
confectionery froastings: 80.00000240.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 120.00000280.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 16.0000032.00000
soft candy: 100.00000240.00000
soups: --
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 1.0000015.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 1.0000015.00000
Edible ices, including sherbet and sorbet (03.0): 10.00000150.00000
Processed fruit (04.1): 1.0000015.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): 1.0000015.00000
Confectionery (05.0): 100.000001500.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): 10.00000150.00000
Meat and meat products, including poultry and game (08.0): 1.0000015.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 1.0000015.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 1.0000015.00000
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 100.000001500.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 100.000001500.00000
Ready-to-eat savouries (15.0): 1.0000015.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 1.0000015.00000
 
Safety References:
European Food Safety Athority(efsa):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on Flavouring Group Evaluation 9, Revision 4 (FGE.09Rev4): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 9, Revision 5 (FGE.09Rev5): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 9, Revision 6 (FGE.09Rev6): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf

EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :583664
National Institute of Allergy and Infectious Diseases:Data
bis[5-methyl-2-(propan-2-yl)cyclohexyl] pentanedioate
Chemidplus:0883215029
 
References:
Leffingwell:Chirality or Article
 bis[5-methyl-2-(propan-2-yl)cyclohexyl] pentanedioate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):583664
Pubchem (sid):53414751
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
For Odor
balsamic
iso
bornyl formate
FL/FR
dextro-
fenchone
FL/FR
camphoreous
camphor tree bark oil
FL/FR
beta-homo
cyclocitral
FL/FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
citrus
ocimene quintoxide
FL/FR
earthy
(-)-alpha-
fenchol
FL/FR
ethereal
cyclohexyl formate
FL/FR
floral
iso
butyl salicylate
FL/FR
dihydrocarvyl acetate
FL/FR
fruity
cyclohexyl acetate
FL/FR
pineapple pentenoate
FL/FR
tropical trithiane
FL/FR
vanilla carboxylate
FL/FR
green
manzanate (Givaudan)
FL/FR
3,5,5-
trimethyl hexanol
FL/FR
herbal
1,4-
cineole
FL/FR
1,8-
cineole
FL/FR
geranic oxide
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
hyssop oil
FL/FR
jambu oleoresin
FL/FR
spike
lavender oil
FL/FR
myrtenol
FL/FR
piperitone
FL/FR
sabinene hydrate
FL/FR
theaspirane
FL/FR
medicinal
meta-
dimethyl hydroquinone
FL/FR
mentholic
cornmint oil
FL/FR
cornmint oil china
FL/FR
cornmint oil terpeneless
FL/FR
dextro-neo
menthol
FL/FR
dextro,laevo-
menthol
FL/FR
(±)-
menthol
FL/FR
laevo-
menthol
FL/FR
(±)-iso
menthone
FL/FR
menthyl acetate
FL/FR
laevo-
menthyl acetate
FL/FR
peppermint cyclohexanone
FL/FR
dextro-
piperitone
FL/FR
minty
betula lenta bark oil america
FL/FR
cornmint oil japan
FL/FR
homo
menthol
FL/FR
(±)-
menthone
FL/FR
(-)-
menthone
FL/FR
homo
menthyl acetate
FL/FR
laevo-
menthyl lactate
FL/FR
pennyroyal oil
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint oil america
FL/FR
peppermint oil idaho
FL/FR
peppermint oil special fractions
FL/FR
peppermint oil willamette
FL/FR
laevo-
piperitone
FL/FR
iso
pulegol
FL/FR
(-)-iso
pulegol
FL/FR
spearmint oil america
FL/FR
WS-23
FL/FR
naphthyl
para-
methyl anisole
FL/FR
odorless
dextro,laevo-
menthone glycerine acetal
FL/FR
spicy
4-
carvomenthenol
FL/FR
myrtenal
FL/FR
sulfurous
mango thiol
FL/FR
terpenic
juniperus communis fruit oil
FL/FR
woody
camphene
FL/FR
(+)-
camphene
FL/FR
For Flavor
No flavor group found for these
(+)-
camphene
FL/FR
camphoreous
camphoreous
camphene
FL/FR
camphor tree bark oil
FL/FR
(-)-alpha-
fenchol
FL/FR
fenchol
FL/FR
laevo-
fenchone
FL/FR
geranic oxide
FL/FR
6-
hydroxydihydrotheaspirane (mixture of isomers)
FL/FR
chemical
meta-
dimethyl hydroquinone
FL/FR
cooling
(2S,5R)-N-[4-(2-
amino-2-oxoethyl)phenyl]-5-methyl-2-(propan-2-yl)cyclohexanecarboxamide
FL
N-para-
benzene acetonitrile menthane carboxamide
FL
iso
butyl salicylate
FL/FR
4-
carvomenthenol
FL/FR
1,4-
cineole
FL/FR
beta-homo
cyclocitral
FL/FR
N-
cyclopropyl-5-methyl-2-isopropylcyclohexane-carboxamide
FL
1,3-
dihydroxyacetone (dimer)
FL
dextro-
fenchone
FL/FR
1-(2-
hydroxy-4-methyl cyclohexyl) ethanone
FL
jambu oleoresin
FL/FR
spike
lavender oil
FL/FR
manzanate (Givaudan)
FL/FR
dextro,laevo-
menthol
FL/FR
laevo-
menthol
FL/FR
iso
menthol
FL
laevo-
menthone 1,2-glycerol ketal
FL
dextro,laevo-
menthone glycerine acetal
FL/FR
homo
menthyl acetate
FL/FR
menthyl acetate
FL/FR
laevo-
menthyl lactate
FL/FR
mono
menthyl succinate
FL
2-(4-
methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide
FL
peppermint oil america
FL/FR
N-(2-(
pyridin-2-yl)ethyl)-3-para-menthane carboxamide
FL
sabinene hydrate
FL/FR
theaspirane
FL/FR
WS-12
FL
WS-3
FL
WS-5
FL
earthy
panax quinquefolius root extract
FL
floral
dihydrocarvyl acetate
FL/FR
fruity
pineapple pentenoate
FL/FR
tropical trithiane
FL/FR
vanilla carboxylate
FL/FR
green
cyclohexyl formate
FL/FR
ocimene quintoxide
FL/FR
iso
phorone
FL
3,5,5-
trimethyl hexanol
FL/FR
herbal
hyssop oil
FL/FR
juniper berry flavor
FL
mentholic
cornmint oil
FL/FR
cornmint oil terpeneless
FL/FR
(±)-
menthol
FL/FR
dextro-neo
menthol
FL/FR
menthol flavor
FL
peppermint cyclohexanone
FL/FR
minty
betula lenta bark oil america
FL/FR
1,8-
cineole
FL/FR
cornmint oil china
FL/FR
cornmint oil japan
FL/FR
limonene glycol
FL
homo
menthol
FL/FR
(±)-iso
menthone
FL/FR
(±)-
menthone
FL/FR
(-)-
menthone
FL/FR
laevo-
menthyl acetate
FL/FR
mint flavor
FL
myrtenal
FL/FR
myrtenol
FL/FR
pennyroyal oil
FL/FR
pennyroyal oil fractions
FL/FR
peppermint absolute
FL/FR
peppermint flavor
FL
peppermint oil idaho
FL/FR
peppermint oil special fractions
FL/FR
peppermint oil willamette
FL/FR
dextro-
piperitone
FL/FR
piperitone
FL/FR
laevo-
piperitone
FL/FR
iso
pulegol
FL/FR
(-)-iso
pulegol
FL/FR
spearmint oil america
FL/FR
WS-23
FL/FR
naphthyl
para-
methyl anisole
FL/FR
solvent
cyclohexyl acetate
FL/FR
sulfurous
mango thiol
FL/FR
terpenic
juniperus communis fruit oil
FL/FR
woody
iso
bornyl formate
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 mint extracts
Search Trop Picture
 
Synonyms:
 glutaric acid di-(-)-menthyl ester
 glutaric acid di-(p-menth-3-yl) ester
 glutaric acid di-(para-menth-3-yl) ester
 glutaric acid, di-(-)-menthyl ester
bis[5-methyl-2-(propan-2-yl)cyclohexyl] pentanedioate
 pentane dioic acid bis(5-methyl-2-(1-methyl ethyl)cyclohexyl) ester
 pentanedioic acid bis(5-methyl-2-(1-methylethyl)cyclohexyl) ester
 

Articles:

 None found yet.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2018 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy