EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

pyridine, 2-methoxy-

Supplier Sponsors

CAS Number: 1628-89-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:216-623-8
Nikkaji Web:J7.535C
Beilstein Number:0108189
XlogP3:1.40 (est)
Molecular Weight:109.12799000
Formula:C6 H7 N O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:2156 2-methoxypyridine
FEMA Number:4639 2-methoxypyridine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):1628-89-3 ; 2-METHOXYPYRIDINE
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.04400 to 1.05000 @ 20.00 °C.
Pounds per Gallon - (est).: 8.697 to 8.747
Refractive Index:1.50100 to 1.50700 @ 20.00 °C.
Boiling Point: 142.00 to 144.00 °C. @ 760.00 mm Hg
Vapor Pressure:7.114000 mmHg @ 25.00 °C. (est)
Flash Point: 89.00 °F. TCC ( 31.67 °C. )
logP (o/w): 1.340
Soluble in:
 water, 7855 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
green fermented tea
Odor Description:at 0.10 % in propylene glycol. green fermented tea
Flavor Type: burnt
burnt mustard
Taste Description: burnt, mustard-like
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Ambles Nature et Chimie
Beijing Lys Chemicals
2-Methoxy pyridine
BOC Sciences
For experimental / research use only.
2-Methoxypyridine 98%
M&U International
Penta International
Sigma-Aldrich: Aldrich
For experimental / research use only.
2-Methoxypyridine 98%
Sunaux International
2-Methoxy Pyridine
For experimental / research use only.
2-Methoxypyridine >96.0%(GC)
Tengzhou Jitian Aroma Chemiclal
Tianjin Danjun International
2-Methoxy pyridine
2-Methoxy pyridine
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 10 - Flammable.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/39 - Wear suitable clothing and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
flavoring agents
Recommendation for 2-methoxypyridine usage levels up to:
 not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: 0.200005.00000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: 0.100002.00000
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: 0.200005.00000
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :74201
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):74201
Pubchem (sid):135032872
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.39.9100
Potential Blenders and core components note
For Odor
ethyl formate
acetaldehyde diisoamyl acetal
cognac oil
For Flavor
No flavor group found for these
acetaldehyde diisoamyl acetal
acetyl-2-isopropenyl pyridine
ethyl formate
cognac oil
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
2-methoxy pyridine
 methyl 2-pyridyl ether
 pyridine, 2-methoxy-


US Patents:3,952,024 - Furfurylthioacetone
PubMed:Highly linear selective cobalt-catalyzed addition of aryl imines to styrenes: reversing intrinsic regioselectivity by ligand elaboration.
US Patents:Certain 2,5-dimethyl-3-thiopyrazines
PubMed:Triflic anhydride mediated synthesis of imidazo[1,5-a]azines.
PubMed:HIV-1 associated Topoisomerase II╬▓ kinase: a potential pharmacological target for viral replication.
PubMed:Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors.
PubMed:Preparation of THP-ester-derived pyridinium-type salts and their reactions with various nucleophiles.
PubMed:Deprotonative metalation of aromatic compounds by using an amino-based lithium cuprate.
PubMed:Characterization of two hydroxytrichloropicolinic acids: application of the one-bond chlorine-isotope effect in 13C NMR.
PubMed:In search of conformationally chiral square-planar complexes: dichloridobis(2-methoxypyridine-kappaN)copper(II).
PubMed:Electron-transfer oxidation of coenzyme B12 model compounds and facile cleavage of the cobalt(IV)-carbon bond via charge-transfer complexes with bases. A negative temperature dependence of the rates.
PubMed:Influence of two insecticides, chlorpyrifos and quinalphos, on arginine ammonification and mineralizable nitrogen in two tropical soil types.
PubMed:Dissipation of chlorpyrifos in two soil environments of semi-arid India.
PubMed:Lithiation of 2-chloro- and 2-methoxypyridine with lithium dialkylamides: initial ortho-direction or subsequent lithium ortho-stabilization?
PubMed:Acid-base equilibria in nonpolar media. 2.(1) Self-consistent basicity scale in THF solution ranging from 2-methoxypyridine to EtP(1)(pyrr) phosphazene.
PubMed:Lithiation of 2-heterosubstituted pyridines with BuLi-LiDMAE: evidence for regiospecificity at C-6.
PubMed:A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor.
PubMed:Ethyl 6-amino-2-methoxypyridine-3-carboxylate, interplay of molecular and supramolecular structure.
PubMed:Studies of the synthesis and thermochemistry of coordinatively unsaturated chelate complexes (eta 5-C5Me5)IrL2 (L2 = TsNCH2CH2NTs, TsNCH2CO2, CO2CO2).
PubMed:An efficient synthesis of 5-bromo-2-methoxy-6-methylaminopyridine-3carboxylic acid.
PubMed:cis-Dichloro(dimethyl sulfoxide-S)(2-methoxypyridine-N)platinum(II).
PubMed:Synthesis and antiinflammatory activity of 6-oxo-1-(beta-D-ribofuranosyl)nocotinic acid and related derivatives.
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy