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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow crystalline powder (est) |
| Assay: | 98.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 58.00 to 61.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 760.00 to 223.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.081000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 190.00 °F. TCC ( 87.78 °C. )
|
| logP (o/w): | 1.987 (est) |
| Soluble in: |
| | alcohol | | | water, very slightly | | | water, 2175 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor Type: fruity |
| almond bitter almond phenolic cherry |
| Odor Description:at 1.00 % in dipropylene glycol. bitter almond phenolic |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
gavage-rat LD50 [sex: M,F] 1520 mg/kg
(Mondino, 1982)
oral-rat LD50 [sex: M,F] 1520 mg/kg
(Peano & Berruto, 1982)
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for 4-methyl salicylaldehyde usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.61 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.30 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 13 |
| Click here to view publication 13 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 2.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | 0.50000 |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 0.50000 |
| fruit ices: | - | - |
| gelatins / puddings: | - | 1.00000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 0.50000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | 1.00000 |
| nut products: | - | 0.50000 |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | 0.50000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | 0.50000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23
View page or View pdf
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Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
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Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
|
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):698-27-1 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :61200 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 2-hydroxy-4-methylbenzaldehyde |
| Chemidplus:0000698271 |
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| anisic |
ortho- acetanisole
FL/FR |
ortho- anisaldehyde
FL/FR |
| balsamic |
2- acetyl furan
FL/FR |
sumatra benzoin absolute
FL/FR |
benzyl cinnamate
FL/FR |
methyl (E)-cinnamate
FL/FR |
methyl cinnamate
FL/FR |
| berry |
raspberry ketone methyl ether
FL/FR |
| bready |
furfural
FL/FR |
| buttery |
3,4- hexane dione
FL/FR |
| camphoreous |
butyrophenone
FL/FR |
dextro- camphor
FL/FR |
| chocolate |
chocolate pyrazine A
FL/FR |
2- methoxy-3-methyl pyrazine
FL/FR |
vanillyl ethyl ether
FL/FR |
| creamy |
para- vanillyl alcohol
FL/FR |
| ethereal |
cyclohexyl formate
FL/FR |
| floral |
acetophenone
FL/FR |
benzyl alcohol
FL/FR |
dimethyl anthranilate
FL/FR |
phenyl acetaldehyde diisobutyl acetal
FL/FR |
| fruity |
allyl 2-ethyl butyrate
FL/FR |
allyl benzoate
FR |
allyl isovalerate
FL/FR |
bitter almond oil
FL/FR |
iso amyl 2-methyl butyrate
FL/FR |
amyl butyrate
FL/FR |
para- anisyl propionate
FL/FR |
benzaldehyde
FL/FR |
benzaldehyde glycrol acetal
FL/FR |
2- benzofuran carboxaldehyde
FL/FR |
bread thiophene
FL/FR |
cherry oxyacetate
FL/FR |
cherry pentenoate
FL/FR |
cherry propanol
FL/FR |
cyclohexyl cinnamate
FL/FR |
4- ethyl benzaldehyde
FL/FR |
ethyl benzoyl acetate
FL/FR |
ethyl methyl-para-tolyl glycidate
FL/FR |
heptyl isobutyrate
FL/FR |
3- methyl-2-butenal
FL/FR |
meta- tolualdehyde
FL/FR |
para- tolualdehyde
FL/FR |
tolualdehyde glyceryl acetal
FL/FR |
tolualdehydes (mixed o,m,p)
FL/FR |
| green |
benzaldehyde dimethyl acetal
FL/FR |
diphenyl oxide
FL/FR |
phenyl acetaldehyde diethyl acetal
FL/FR |
seaweed absolute (fucus vesiculosus et serratus)
FL/FR |
| herbal |
laevo- perillaldehyde
FL/FR |
yerba mate absolute
FL/FR |
| honey |
methyl phenyl acetate
FL/FR |
phenyl pyruvic acid
FL/FR |
| medicinal |
2,6- xylenol
FL/FR |
| minty |
piperitenone
FL/FR |
| mossy |
veramoss (IFF)
FR |
| naphthyl |
2,4- dimethyl benzaldehyde
FL/FR |
| nutty |
3,5- cocoa pyrazine
FL/FR |
2- methyl-3-(methyl thio) pyrazine
FL/FR |
2- methyl-3-ethoxypyrazine
FL/FR |
nutty cyclohexenone
FL/FR |
| phenolic |
anisole
FL/FR |
2,3- dimethyl benzofuran
FL/FR |
para-alpha- dimethyl styrene
FL/FR |
ortho- guaiacol
FL/FR |
2'- hydroxyacetophenone
FL/FR |
methyl benzoate
FL/FR |
4- methyl-2,6-dimethoxyphenol
FL/FR |
piper betle leaf oil
FR |
2- propyl phenol
FL/FR |
4- propyl phenol
FL/FR |
4- vinyl phenol
FL/FR |
2,5- xylenol
FL/FR |
2,3- xylenol
FL/FR |
| powdery |
para- anisyl acetate
FL/FR |
dibenzyl ketone
FL/FR |
| smoky |
4- ethyl phenol
FL/FR |
pyroligneous acids
FL/FR |
| spicy |
cinnamyl isovalerate
FL/FR |
4- ethyl guaiacol
FL/FR |
para- methoxycinnamaldehyde
FL/FR |
(E)-para- methoxycinnamaldehyde
FL/FR |
4- methyl guaiacol
FL/FR |
zingerone
FL/FR |
| vanilla |
ortho- dimethyl hydroquinone
FL/FR |
| woody |
guaiacyl acetate
FL/FR |
beta- thujaplicin
FR |
| For Flavor |
| No flavor group found for these |
para- anisyl propionate
FL/FR |
butyrophenone
FL/FR |
chavicol
FL |
chocolate pyrazine A
FL/FR |
2,4- dihydroxybenzoic acid
FL |
2,6- dimethoxy-4-vinyl phenol
FL |
ortho- dimethyl hydroquinone
FL/FR |
ethyl 2-phenyl-3-furoate
FL |
4- ethyl benzaldehyde
FL/FR |
5- ethyl-2-thiophene carboxaldehyde
FL |
2- hexenal
FL |
(E)-para- methoxycinnamaldehyde
FL/FR |
methyl (E)-cinnamate
FL/FR |
3- methyl crotonic acid
FL |
methyl furfuracrylate
FL |
2- methyl-3-(methyl thio) pyrazine
FL/FR |
2- methyl-3-ethoxypyrazine
FL/FR |
phenyl acetaldehyde diethyl acetal
FL/FR |
piperitenone
FL/FR |
2- propyl phenol
FL/FR |
4- propyl phenol
FL/FR |
para- salicylic acid
FL |
seaweed absolute (fucus vesiculosus et serratus)
FL/FR |
tolualdehyde glyceryl acetal
FL/FR |
| anisic |
| anisic |
ortho- anisaldehyde
FL/FR |
| aromatic |
anisole
FL/FR |
laevo- perillaldehyde
FL/FR |
| berry |
heptyl isobutyrate
FL/FR |
raspberry ketone methyl ether
FL/FR |
| bitter |
dibenzyl ketone
FL/FR |
| brown |
furfural
FL/FR |
| burnt |
2,6- xylenol
FL/FR |
| buttery |
3,4- hexane dione
FL/FR |
| chemical |
2,3- dimethyl benzofuran
FL/FR |
| cherry |
para- methoxycinnamaldehyde
FL/FR |
| creamy |
para- vanillyl alcohol
FL/FR |
| ethereal |
allyl 2-ethyl butyrate
FL/FR |
| fishy |
3- penten-2-one
FL |
| floral |
methyl phenyl acetate
FL/FR |
| fruity |
allyl isovalerate
FL/FR |
bitter almond oil
FL/FR |
iso amyl 2-methyl butyrate
FL/FR |
amyl butyrate
FL/FR |
para- anisyl acetate
FL/FR |
benzaldehyde
FL/FR |
benzaldehyde glycrol acetal
FL/FR |
benzyl alcohol
FL/FR |
bread thiophene
FL/FR |
cherry laurel oil
FL |
cherry oxyacetate
FL/FR |
cherry pentenoate
FL/FR |
cherry propanol
FL/FR |
cinnamyl isovalerate
FL/FR |
cyclohexyl cinnamate
FL/FR |
dimethyl anthranilate
FL/FR |
ethyl benzoyl acetate
FL/FR |
ethyl methyl-para-tolyl glycidate
FL/FR |
2,4- hexadien-1-ol
FL |
3- methyl-2-butenal
FL/FR |
meta- tolualdehyde
FL/FR |
tolualdehydes (mixed o,m,p)
FL/FR |
| green |
benzaldehyde dimethyl acetal
FL/FR |
cyclohexyl formate
FL/FR |
diphenyl oxide
FL/FR |
phenyl acetaldehyde diisobutyl acetal
FL/FR |
| herbal |
yerba mate absolute
FL/FR |
| meaty |
2,6- dimethyl thiophenol
FL |
ortho- thioguaiacol
FL |
| medicinal |
dextro- camphor
FL/FR |
| musty |
2- ethoxythiazole
FL |
2,5- xylenol
FL/FR |
| naphthyl |
2,4- dimethyl benzaldehyde
FL/FR |
2'- hydroxyacetophenone
FL/FR |
| nutty |
2- acetyl furan
FL/FR |
2- benzofuran carboxaldehyde
FL/FR |
3,5- cocoa pyrazine
FL/FR |
3,5(6)- cocoa pyrazine
FL |
2- methoxy-3-methyl pyrazine
FL/FR |
nutty cyclohexenone
FL/FR |
| phenolic |
methyl benzoate
FL/FR |
4- methyl-2,6-dimethoxyphenol
FL/FR |
phenyl pyruvic acid
FL/FR |
4- vinyl phenol
FL/FR |
2,3- xylenol
FL/FR |
| powdery |
ortho- acetanisole
FL/FR |
acetophenone
FL/FR |
powdery ketone
FL |
| rummy |
vanillyl ethyl ether
FL/FR |
| smoky |
4- ethyl phenol
FL/FR |
pyroligneous acids
FL/FR |
| spicy |
sumatra benzoin absolute
FL/FR |
benzyl cinnamate
FL/FR |
para-alpha- dimethyl styrene
FL/FR |
methyl cinnamate
FL/FR |
4- methyl guaiacol
FL/FR |
para- tolualdehyde
FL/FR |
zingerone
FL/FR |
| woody |
4- ethyl guaiacol
FL/FR |
ortho- guaiacol
FL/FR |
guaiacyl acetate
FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzaldehyde, 2-hydroxy-4-methyl- | | 2,4- | cresotaldehyde | | 2- | formyl-5-methylphenol | | 2- | hydroxy-4-methyl benzaldehyde | | 2- | hydroxy-4-methyl-benzaldehyde | | 2- | hydroxy-4-methylbenzaldehyde | | 4- | methyl salicylic aldehyde | | 4- | methyl-2-hydroxybenzaldehyde | | 4- | methylsalicyclic aldehyde | | 3- | methylsalicylaldehyde | | 4- | methylsalicylaldehyde | | m-homo | salicylaldehyde | | meta-homo | salicylaldehyde | | homo | salicylaldehyde, m- |
Articles:
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3D/inchi
