(-)-isolongifolene
2H-2,4a-methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)-

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  Foreverest Resources Ltd.

  Leading pine based chemicals supplier
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  FOREVERESTA® F&F RAW MATERIALS is a range of natural extracts and synthetic aroma chemicals based on the rich material resources and great supply network from China, which was applied for specialty chemicals industry. The markets cover application areas on food, beverage, custom fragrance, fine perfume, personal care, cosmetics, etc.
  Foreverest Resources Ltd. is a materials supplier, exporting gum turpentine based, terpene derivertives and natural/extracted monomers and intermediates from China since 1988. We offers high quality raw materials for flavors and fragrances synthetic manufacturing in the world.
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  Isolongifolene has woody and amber incense odors, has been widely used as fragrances in cosmetics, perfumers, space sprays, detergents, deodorants, fabrics, fibers, and soap, tobacco, creams, paper products. In addition, Isolongifolene inhibits tyrosinase that is multifunctional copper-containing enzyme for melanin biosynthesis in plants and animals, also, hydrogenated Isolongifolene has been used as a bridged core to prepare a chiral ligand for the estrogen receptor that could be useful in regulating fertility, preventing, and treating breast cancer, and for menopausal hormone replacement. Isolongifolene also used as a natural insecticide and pesticide.

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  Lluch Essence S.L.

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  SRS Aromatics Ltd

  For over 25 years
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  As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
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Name: (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene CAS Number: 1135-66-6 3D/inchi ECHA EINECS - REACH Pre-Reg: 214-494-2 FDA UNII: E0LN4V7EY4 Beilstein Number: 2207559 MDL: MFCD00042616 XlogP3-AA: 5.00 (est) Molecular Weight: 204.35628000 Formula: C15 H24 NMR Predictor: Predict (works with chrome, Edge or firefox) EFSA/JECFA Comments: No longer supported by Industry (DG SANCO, 2012). Category:fragrance agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: colorless to pale yellow clear liquid (est) Assay: 95.00 to 100.00 sum of isomers Food Chemicals Codex Listed: No Specific Gravity: 0.92600 to 0.93200 @ 25.00 °C. Pounds per Gallon - (est).: 7.705 to 7.755 Refractive Index: 1.49500 to 1.50100 @ 20.00 °C. Boiling Point: 255.00 to 257.00 °C. @ 760.00 mm Hg Vapor Pressure: 0.014000 mmHg @ 25.00 °C. (est) Flash Point: 216.00 °F. TCC ( 102.22 °C. ) logP (o/w): 6.150 (est) Soluble in:   alcohol   water, 0.1401 mg/L @ 25 °C (est) Insoluble in:   water   Organoleptic Properties: Odor Type: woody woody dusty amber incense Odor Description:at 100.00 %. woody dusty amber incense Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: perfuming agents   Suppliers: Anhui Haibei isoLongifolene Odor: Pine woody ExtraSynthese For experimental / research use only. isoLongifolene (GC) ≥98% (sum of enantiomers) Foreverest Resources Isolongifolene 85% Odor: characteristic Use: Isolongifolene has woody and amber incense odors, has been widely used as fragrances in cosmetics, perfumers, space sprays, detergents, deodorants, fabrics, fibers, and soap, tobacco, creams, paper products. In addition, Isolongifolene inhibits tyrosinase that is multifunctional copper-containing enzyme for melanin biosynthesis in plants and animals, also, hydrogenated Isolongifolene has been used as a bridged core to prepare a chiral ligand for the estrogen receptor that could be useful in regulating fertility, preventing, and treating breast cancer, and for menopausal hormone replacement. Isolongifolene also used as a natural insecticide and pesticide. Fuzhou Farwell Iso Longifolene 75%/80% Lluch Essence ISOLONGIFOLENE Moellhausen IsoLONGIFOLENE Odor: soft woody, slightly dusty Penta International ISOLONGIFOLENE Reincke & Fichtner isoLongifolene Santa Cruz Biotechnology For experimental / research use only. (-)-isoLongifolene ≥91% Sigma-Aldrich: Aldrich For experimental / research use only. (-)-Isolongifolene ≥98.0% (sum of enantiomers, GC) sds SRS Aromatics ISOLONGIFOLENE   Safety Information: Preferred SDS: View European information : Most important hazard(s): Xi - Irritant R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: Not determined Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: fragrance agents RIFM Fragrance Material Safety Assessment: Search IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice Recommendation for (-)-isolongifolene usage levels up to:   4.0000 % in the fragrance concentrate.   Maximised Survey-derived Daily Intakes (MSDI-EU): 0.012 (μg/capita/day) Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3500 (μg/person/day) Threshold of Concern: 1800 (μg/person/day) Structure Class: I   Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.   average usage mg/kg maximum usage mg/kg Dairy products, excluding products of category 02.0 (01.0): 7.00000 35.00000 Fats and oils, and fat emulsions (type water-in-oil) (02.0): 5.00000 25.00000 Edible ices, including sherbet and sorbet (03.0): 10.00000 50.00000 Processed fruit (04.1): 7.00000 35.00000 Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): - - Confectionery (05.0): 10.00000 50.00000 Chewing gum (05.3): - - Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.00000 25.00000 Bakery wares (07.0): 10.00000 50.00000 Meat and meat products, including poultry and game (08.0): 2.00000 10.00000 Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 2.00000 10.00000 Eggs and egg products (10.0): - - Sweeteners, including honey (11.0): - - Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 5.00000 25.00000 Foodstuffs intended for particular nutritional uses (13.0): 10.00000 50.00000 Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 5.00000 25.00000 Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 10.00000 50.00000 Ready-to-eat savouries (15.0): - - Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.00000 25.00000   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Flavouring Group Evaluation 25, (FGE.25)[1] - Aliphatic and aromatic hydrocarbons from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf Flavouring Group Evaluation 78 (FGE.78)[1] - Consideration of Aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25 - Scientific Opinion of the Panel on Food Additives,Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf Scientific Opinion on Flavouring Group Evaluation 25Rev1: Aliphatic and aromatic hydrocarbons from chemical group 31 View page or View pdf Scientific Opinion on Flavouring Group Evaluation 78, Revision 1 (FGE.78Rev1): Consideration of aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25Rev2 View page or View pdf Scientific Opinion on Flavouring Group Evaluation 25, Revision 2 (FGE.25Rev2): Aliphatic and aromatic hydrocarbons from chemical group 31 View page or View pdf Scientific opinion on Flavouring Group Evaluation 25, Revision 3 (FGE.25Rev3): Aliphatic hydrocarbons from chemical group 31 View page or View pdf EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):1135-66-6 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :102562 National Institute of Allergy and Infectious Diseases:Data WISER:UN 2319 WGK Germany:3 (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene Chemidplus:0001135666   References:   (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 1135-66-6 Pubchem (cid): 102562 Pubchem (sid): 135058579 Pherobase: View   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements HMDB (The Human Metabolome Database): Search Typical G.C. VCF-Online: VCF Volatile Compounds in Food ChemSpider: View   Potential Blenders and core components note For Odor aldehydic 2- methyl undecanal dimethyl acetal FR amber amber decane FR cistus ladaniferus absolute resin FL/FR balsamic mastic gum resin FR opoponax absolute (commiphora erythraea var. glabrescens engle) FL/FR opoponax absolute replacer FR opoponax resinoid (commiphora erythraea var. glabrescens engle) FR opoponax resinoid replacer FR floral linalool terpenes FR waxy tetradecanal FL/FR woody amber dioxane FR amber formate FR cedryl methyl ether FR frankincense resin FL/FR (±)- tetrahydronootkatone FL/FR tobacarol (IFF) FR For Flavor No flavor group found for these (±)- tetrahydronootkatone FL/FR amber amber cistus ladaniferus absolute resin FL/FR balsamic opoponax absolute (commiphora erythraea var. glabrescens engle) FL/FR fatty tetradecanal FL/FR woody frankincense resin FL/FR   Potential Uses: None Found   Occurrence (nature, food, other):note   juniper branch oil @ 0.50% Data GC Search Trop Picture   Synonyms: 1,3,4,5,6,7- hexahydro-1,1,5,5-tetramethyl-2H-2,4-methanophthalene (2S,4aR)-1,3,4,5,6,7- hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene (2S)-1,3,4,5,6,7- hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene   hexahydrotetramethyl methanonaphthalene (-)-iso longifolene iso longifolene 2H-2,4a- methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl- 2H-2,4a- methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)- 2,2,7,7- tetramethyl tricyclo(6.2.1(1,8).0(1,6))undec-5-ene   Articles:   None found yet. 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Notes: None found