dihydroxyacetone (monomer)
a ketotriose compound. its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. it is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. in combination with naphthoquinones it acts as a sunscreening agent. Prod. by microorganisms, e.g. Corynebacterium diphtheriae (CCD) Dihydroxyacetone or DHA, also known as glycerone, is a triose with formula C3H6O3. DHA is primarily used as an ingredient in sunless tanning products. It is often derived from plant sources such as sugar beets and sugar cane, and by the fermentation of glycerin. (Wikipedia)
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve and our roster of products and services continues to grow with us. Personal care ingredients now include a substantial array of luxury and exotic components. Substantial inroads have been made in the nutraceutical and resins markets, with a growing roster of versatile and unique ingredients. And we continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions.
      Email: Sales
      Voice: 203-299-3220
      Fax: 203-299-1355
      Products List: View
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co.
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
      Email: Info
      Email: Sales
      Voice: 86-510-86023169
      Fax: 86-510-86023170
      Natural Food Colour
      New functional food ingredients
      101944 1,3 -Dihydroxyacetone
      HLC-102 Dihydroxyacetone
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
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      04-21400 1,3-DIHYDROXYACETONE
Synonyms   Articles   Notes   Search
1,3-dihydroxypropan-2-one (Click)
CAS Number: 96-26-4Picture of molecule
ECHA EINECS - REACH Pre-Reg: 202-494-5
Nikkaji Web: J4.719H
Beilstein Number: 1740268
XlogP3-AA: -1.40 (est)
Molecular Weight: 90.07842000
Formula: C3 H6 O3
NMR Predictor: Predict (works with chrome or firefox)
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 4033  dihydroxyacetone (monomer)
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Physical Properties:
Appearance: white to tan powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 88.00 to  90.00 °C. @ 760.00 mm Hg
Boiling Point: 212.00 to  214.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.021000 mm/Hg @ 25.00 °C.
Flash Point: 207.00 °F. TCC ( 97.22 °C. )
logP (o/w): -0.779 (est)
Shelf Life: 12.00 month(s) or longer if stored properly.
Storage: refrigerate in tightly sealed containers.
Soluble in:
 water, 5.032e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
Odor Type: minty
Odor Strength: medium
Odor Description:
at 100.00 %. 
 sweet  cooling  
Taste Description:
sweet cooling
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: reducing agents
skin conditioning
tanning agents
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BOC Sciences
For experimental / research use only.
Dihydroxyacetone 98%
For experimental / research use only.
Charkit Chemical
EMD Millipore
For experimental / research use only.
Inoue Perfumery
Jiangyin Healthway
1,3 -Dihydroxyacetone
New functional food ingredients
Jiangyin Healthway
Odor: characteristic
Use: The best self tanning agent for gaining a natural tan-like appearance without sun exposure
dihydroxyacetone (monomer)
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LDLo  80000 mg/kg
United States Patent Document. Vol. #4049795

intraperitoneal-rat LD50  8750 mg/kg
United States Patent Document. Vol. #4049795

intraperitoneal-rabbit LD  > 8000 mg/kg
United States Patent Document. Vol. #4049795

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavoring agents
Recommendation for dihydroxyacetone (monomer) usage levels up to:
 not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 21
Click here to view publication 21
 average usual ppmaverage maximum ppm
baked goods: 50.00000200.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: 120.00000600.00000
cheese: --
chewing gum: --
condiments / relishes: 300.000001200.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 80.00000320.00000
fruit ices: --
gelatins / puddings: 40.00000240.00000
granulated sugar: --
gravies: 80.00000240.00000
hard candy: 300.000001200.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 20.00000200.00000
milk products: 40.00000200.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: 80.00000240.00000
reconstituted vegetables: --
seasonings / flavors: 400.000002400.00000
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 96-26-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 670
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
Chemidplus: 0000096264
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 96-26-4
Pubchem (cid): 670
Pubchem (sid): 134972376
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
Golm Metabolome Database: Search
KEGG (GenomeNet): C00184
HMDB (The Human Metabolome Database): HMDB01882
FooDB: FDB009294
YMDB (Yeast Metabolome Database): YMDB00018
Haz-Map: View
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
None Found
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Potential Uses:
 reducing agents 
 skin conditioning 
 tanning agents 
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Occurrence (nature, food, other): note
 not found in nature
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 acetone, dihydroxy-
 chromelin (monomer)
 dihydroxy acetone
1,3-dihydroxy acetone
1,3-dihydroxy propan-2-one
2,5-(2R,5S)dihydroxy-1,4-dioxane-2,5-dimethanol (monomer)
trans-2,5-dihydroxy-1,4-dioxane-2,5-dimethanol (monomer)
1,3-dihydroxy-2-propanone (monomer)
1,3-dihydroxyacetone (monomer)
alpha,alpha-dihydroxyacetone (monomer)
1,3-dihydroxydimethyl ketone
(bis)hydroxymethyl ketone (monomer)
bis(hydroxymethyl) ketone
 magic tan
2-propanone, 1,3-dihydroxy-
 quick tan
 tan tone
Synonyms   Articles   Notes   Search   Top
PubMed: Reflections on the catalytic power of a TIM-barrel.
PubMed: Poly(carbonate-ester)s of dihydroxyacetone and lactic acid as potential biomaterials.
PubMed: Structural and biochemical characterization of a recombinant triosephosphate isomerase from Rhipicephalus (Boophilus) microplus.
PubMed: Dihydroxyacetone (DHA) monomer complexes with CaBr2 and CdCl2.
PubMed: Active site of Zn(2+)-dependent sn-glycerol-1-phosphate dehydrogenase from Aeropyrum pernix K1.
PubMed: Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source.
PubMed: Crystal structures of dihydroxyacetone and its derivatives.
PubMed: Chemical modification of specific active site amino acid residues of Enterobacter aerogenes glycerol dehydrogenase.
PubMed: Purification and characterization of 2,5-diketo-D-gluconate reductase from Corynebacterium sp.
PubMed: Fluoride ion as an NMR relaxation probe of galactose oxidase-substrate binding.
PubMed: Lactose and D-galactose metabolism in Staphylococcus aureus. IV. Isolation and properties of a class I D-ketohexose-1,6-diphosphate aldolase that catalyzes the cleavage of D-tagatose 1,6-diphosphate.
PubMed: Purification and characterisation of an unusually heat-stable and acid/base-stable class I fructose-1,6-bisphosphate aldolase from Staphylococcus aureus.
PubMed: Chemical and functional properties of the native and reconstituted forms of the membrane-bound, aerobic glycerol-3-phosphate dehydrogenase of Escherichia coli.
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