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ruscus aculeatus root extract
extract of the roots of the butcheerbroom, ruscus aculeatus, liliaceae

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Name:ruscus aculeatus root extract
CAS Number: 84012-38-4
ECHA EC Number:281-682-9
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: astringents
refreshing agents
skin conditioning
soothing agents
stabilising agents
butcher's broom extract
ECSA Chemicals
Grau Aromatics
Grau Aromatics
Lipotec USA
Actiphyte® of Butcher's Broom Extract
SRS Aromatics
SRS Aromatics
Extrapone® Butcher's Broom GW P
Life Essentials - Botanicals
Vege Tech
butcherbroom root extract
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for ruscus aculeatus root extract usage levels up to:
 not for fragrance use.
Recommendation for ruscus aculeatus root extract flavor usage levels up to:
 not for flavor use.
Safety References:
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
ruscus aculeatus root extract
 ruscus aculeatus root extract
Pubchem (sid):135310013
Other Information:
Export Tariff Code:1302.19.0000
Potential Blenders and core components note
None Found
Potential Uses:
 skin conditioning
 soothing agents
 stabilising agents
Occurrence (nature, food, other):note
 ruscus aculeatus root
Search Trop Picture
extrapone butcher's broom (Symrise)
 butcher's broom extract
actiphyte of butcher's broom extract
extrapone butcher's broom GW P (Symrise)
 butcherbroom root extract
 butchers broom extract
 extract of the roots of the butcheerbroom, ruscus aculeatus, liliaceae
 radix rusci extract


PubMed:Fungal Planet description sheets: 214-280.
PubMed:Hepatoprotective herbs, avicenna viewpoint.
PubMed:Novel steroidal components from the underground parts of Ruscus aculeatus L.
PubMed:Compliance in pharmacotherapy in patients with chronic venous disorders.
PubMed:Bioactive compounds, RP-HPLC analysis of phenolics, and antioxidant activity of some Portuguese shrub species extracts.
PubMed:Correlation between improvement in functional signs and plethysmographic parameters during venoactive treatment (Cyclo 3 Fort).
PubMed:Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl-chalcone and ascorbic acid (quality study).
PubMed:Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications.
PubMed:[Multicentric study on a topical compound with lymph-draining action in the treatment of the phlebostatic ulcer of the inferior limbs].
PubMed:High-throughput LC/MS/MS analysis of ruscogenin and neoruscogenin in Ruscus aculeatus L.
PubMed:Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study'.
PubMed:Changes on venous diameter and leg perimeter with different clinical treatments for moderate chronic venous disease: evaluation using Duplex scanning and perimeter measurements.
PubMed:Possible mechanism of the anti-inflammatory activity of ruscogenin: role of intercellular adhesion molecule-1 and nuclear factor-kappaB.
PubMed:Use of microcirculatory parameters to evaluate clinical treatments of chronic venous disorder (CVD).
PubMed:Clinical and capillaroscopic evaluation in the treatment of chronic venous insufficiency with Ruscus aculeatus, hesperidin methylchalcone and ascorbic acid in venous insufficiency treatment of ambulatory patients.
PubMed:Expression patterns of class I KNOX and YABBY genes in Ruscus aculeatus (Asparagaceae) with implications for phylloclade homology.
PubMed:Chromatographic behaviour of steroidal saponins studied by high-performance liquid chromatography-mass spectrometry.
PubMed:The effect of methyl jasmonate on triterpene and sterol metabolisms of Centella asiatica, Ruscus aculeatus and Galphimia glauca cultured plants.
PubMed:Effect of organogenesis on steroidal saponin biosynthesis in calli cultures of Ruscus aculeatus.
PubMed:Traditional phytotherapy in Central Italy (Marche, Abruzzo, and Latium).
PubMed:Determination of anthocyanins in Ruscus aculeatus L. berries.
PubMed:Meta-analysis of clinical trials of Cyclo 3 Fort in the treatment of chronic venous insufficiency.
PubMed:Spatial variation in springtime food resources influences the winter body mass of roe deer fawns.
PubMed:[Chronic venous insufficiency: an open trial of FLEBS Crema].
PubMed:Identification of Ruscus steroidal saponins by HPLC-MS analysis.
PubMed:Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency.
PubMed:Ruscus aculeatus (butcher's broom). Monograph.
PubMed:Effect of a venotonic agent on the main arteries and veins during a 5 day HDT.
PubMed:[Lymphocytic colitis in a women with Biermer's disease treated with Cirkan].
PubMed:Hemorrhoids and varicose veins: a review of treatment options.
PubMed:Formulation and in vitro release of suppositories containing dry extract of Ruscus aculeatus L.
PubMed:Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report.
PubMed:HPTLC densitometric determination of ruscogenins in dry extract of Ruscus aculeatus L.
PubMed:An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed:Pharmacological assessment of adrenergic receptors in human varicose veins.
PubMed:An open-label, randomised multicentre study comparing the efficacy and safety of CYCLO 3 FORT versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed:Effect of Ruscus extract and hesperidin methylchalcone on hypoxia-induced activation of endothelial cells.
PubMed:Antifungal activity of plant extracts against dermatophytes.
PubMed:Cyclic nucleotides and production of prostanoids in human varicose veins.
PubMed:A spirostanol saponin from the underground parts of Ruscus aculeatus.
PubMed:Aculeoside B, a new bisdesmosidic spirostanol saponin from the underground parts of Ruscus aculeatus.
PubMed:Steroidal saponins from the underground parts of Ruscus aculeatus and their cytostatic activity on HL-60 cells.
PubMed:Antimicrobial activity of 20 plants used in folkloric medicine in the Palestinian area.
PubMed:Antipermeability effects of Cyclo 3 Fort in hamsters with moderate diabetes.
PubMed:New steroidal constituents of the underground parts of Ruscus aculeatus and their cytostatic activity on HL-60 cells.
PubMed:Triterpenes and sterols from Ruscus aculeatus.
PubMed:Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency.
PubMed:Cytolytic hepatitis with a venotonic drug.
PubMed:Possible mechanisms for the inhibitory effect of Ruscus extract on increased microvascular permeability induced by histamine in hamster cheek pouch.
PubMed:Effects of Ruscus extract on the internal diameter of arterioles and venules of the hamster cheek pouch microcirculation.
PubMed:[Cirkan-induced chronic diarrhea].
PubMed:Flavonoids from the Aboveground Parts of Ruscus aculeatus.
PubMed:Localization of calcium on the stigma surface of Ruscus aculeatus L. : Studies using chlorotetracycline and X-ray microanalysis.
PubMed:Improved Isolation and HPLC/TLC Analyses of Major Saponins from Ruscus aculeatus.
PubMed:Use of extract of Ruscus aculeatus in venous disease in the lower limbs.
PubMed:[Controlled study of increasing venous tone in primary varicose veins by oral administration of Ruscus aculeatus and trimethylhespiridinchalcone].
PubMed:Effect of temperature on the responsiveness of cutaneous veins to the extract of Ruscus aculeatus.
PubMed:[Isolation and confirmation of the structure by 13C-NMR of the main prosapogenin from Ruscus aculeatus L].
PubMed:Effect of Ruscus aculeatus on isolated canine cutaneous veins.
PubMed:[Clinical study of the efficacy of Cirkan in phlebology].
PubMed:[The anti-edematous effect of an association of proteolytic enzymes, flavonoids, sterolic heteroside of Ruscus aculeatus and ascorbic acid (author's transl)].
PubMed:[Ruscus aculeatus L.--Butcher's broom, a therapeutic agent in proctology].
PubMed:Quantitative determination of ruscogenin in Ruscus species by densitometric thin-layer chromatography.
PubMed:Constituents of Ruscus aculeatus.
PubMed:Euparone, a new benzofuran from Ruscus aculeatus L.
PubMed:[Mixed prophylaxis of postoperative thrombo-embolic disease in general surgery. Prevention by anticoagulant and vasomotor phlebotropic therapy. Pharmacodynamic and clinical study of Ruscus aculeatus extract].
PubMed:[Research on sterol sapogenins. VIII. Saponosides of butcher's broom (Ruscus aculeatus L.)].
PubMed:[The pharmacological properties of extract of Ruscus aculeatus L].
PubMed:[Value of Ruscus aculeatus in anti-hemorrhoid medication].
PubMed:[Pharmacological research on drug extract of Ruscus aculeatus].
Anti-inflammatories. a plant genus of the family liliaceae. this should not be confused with broom or scotch broom (cytisus) or desert broom (baccharis) or spanish broom (spartium) or brome (bromus).
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