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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless solid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 157.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 263.00 to 264.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.009000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 237.00 °F. TCC ( 113.89 °C. )
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| logP (o/w): | 0.262 (est) |
| Soluble in: |
| | alcohol | | | water, 1.101e+004 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Type: camphoreous |
| sweet camphoreous |
| Odor Description:at 100.00 %. sweet camphor |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for epoxyoxophorone usage levels up to: | | | not for fragrance use.
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| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.20 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1000 (μg/person/day) |
| Threshold of Concern: | 90 (μg/person/day) |
| Structure Class: | III |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 22 |
| Click here to view publication 22 |
| | average usual ppm | average maximum ppm |
| baked goods: | 3.00000 | 15.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | 2.00000 | 10.00000 |
| cheese: | 2.00000 | 10.00000 |
| chewing gum: | - | - |
| condiments / relishes: | 5.00000 | 25.00000 |
| confectionery froastings: | - | - |
| egg products: | 2.00000 | 10.00000 |
| fats / oils: | 2.00000 | 10.00000 |
| fish products: | 3.00000 | 15.00000 |
| frozen dairy: | 5.00000 | 25.00000 |
| fruit ices: | 1.00000 | 5.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | 3.00000 | 15.00000 |
| poultry: | - | - |
| processed fruits: | 1.00000 | 5.00000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | 2.00000 | 10.00000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Flavouring Group Evaluation 31 (FGE.31) - One Epoxide from Chemical Group 32 [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf
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Flavouring Group Evaluation 82 (FGE.82)[1] - Consideration of Epoxides evaluated by JECFA (65th meeting) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 82, Revision 1 (FGE.82Rev1): Consideration of Epoxides evaluated by the JECFA (65th meeting) View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :3853254 |
| National Institute of Allergy and Infectious Diseases:Data |
| 1,3,3-trimethyl-7-oxabicyclo[4.1.0]heptane-2,5-dione |
| Chemidplus:0038284116 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 7-oxa | bicyclo[4.1.0]heptane-2,5-dione, 1,3,3-trimethyl- | | | epoxy oxophorone | | 2,3- | epoxy-2,6,6-trimethyl-1,4-cyclohexanedione | | 3,5,5- | trimethyl-2,3-epoxy-cyclohexane-1,4-dione | | 3,5,5- | trimethyl-2,3-epoxycyclohexane-1,4-dione | | 1,3,3- | trimethyl-7-oxabicyclo-[4.1.0]-heptane-2,5-dione | | 1,3,3- | trimethyl-7-oxabicyclo(4.1.0)heptane-2,5-dione | | 1,3,3- | trimethyl-7-oxabicyclo[4.1.0]heptane-2,5-dione |
Articles:
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