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1,3-butane dithiol
1,3-butanedithiol

Supplier Sponsors

BOC Sciences

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
Email:	Sales
US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
US Voice: 1-631-485-4226
US Fax: 1-631-614-7828
Europe	44-203-286-1088
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CODE103672 CODE103672
Product(s):
24330-52-7 1,3-Butanedithiol

Penta International Corporation

Chemistry innovation
At Penta, our products and services help businesses do business better.
For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
US Email:	Technical Services
US Email:	Sales
US Voice: (973) 740-2300
US Fax: (973) 740-1839
CODE103672 CODE103672
Product(s):
02-44775 1,3-BUTANEDITHIOL

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.
Synerzine is a leading supplier of flavor and fragrance ingredients.
Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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CODE103672 CODE103672
Product(s):
W2241 1,3-Butanedithiol

Name:	butane-1,3-dithiol
CAS Number:	24330-52-7	3D/inchi
ECHA EINECS - REACH Pre-Reg:	246-172-2
FDA UNII:	85VJA9KBCH
Nikkaji Web:	J287.217J
MDL:	MFCD00209500
CoE Number:	11910
XlogP3-AA:	1.60 (est)
Molecular Weight:	122.25370000
Formula:	C4 H10 S2
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:flavoring agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Flavoring:	538 1,3-butanedithiol
DG SANTE Food Flavourings:	12.073 butane-1,3-dithiol
FEMA Number:	3529 1,3-butanedithiol
FDA:	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):	24330-52-7 ; 1,3-BUTANEDITHIOL

Physical Properties:

Appearance:	colorless clear liquid (est)
Assay:	97.00 to 100.00
Food Chemicals Codex Listed:	No
Specific Gravity:	1.05200 @ 20.00 °C.
Refractive Index:	1.52600 to 1.53600 @ 20.00 °C.
Boiling Point:	91.00 to 93.00 °C. @ 30.00 mm Hg
Vapor Pressure:	1.147000 mmHg @ 25.00 °C. (est)
Flash Point:	150.00 °F. TCC ( 65.56 °C. )
logP (o/w):	2.083 (est)
Soluble in:
	fats
	water, 1524 mg/L @ 25 °C (est)
Insoluble in:
	water

Organoleptic Properties:

Odor Type: alliaceous

garlic meaty sulfurous onion spicy

Odor Description:at 0.10 % in propylene glycol. garlic meaty sulfury onion spicy

garlic meaty sulfurous roasted garlic onion spicy nutty

Odor Description:at 0.01 % in ethyl alcohol. Garlic, meaty sulfurous, roasted garlic and onion, spicy, with nutty nuances
Mosciano, Gerard P&F 24, No. 6, 10, (1999)

Flavor Type: alliaceous

garlic mushroom bloody metallic roasted burnt rubbery meaty garlic

Taste Description: at 15.00 - 30.00 ppm. Garlic, mushroom, bloody metallic, roasted burnt rubber nuances, HVP and meaty, garlic
Mosciano, Gerard P&F 24, No. 6, 10, (1999)

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavoring agents
Recommendation for 1,3-butane dithiol usage levels up to:
	not for fragrance use.

Maximised Survey-derived Daily Intakes (MSDI-EU):		ND (μg/capita/day)
Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 11
Click here to view publication 11
		average usual ppm	average maximum ppm
baked goods:		-	0.20000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	0.20000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	0.20000
milk products:		-	-
nut products:		-	0.20000
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	0.20000
soft candy:		-	-
soups:		-	0.20000
sugar substitutes:		-	-
sweet sauces:		-	-

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20
View page or View pdf

Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :520119

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

butane-1,3-dithiol

Chemidplus:0024330527

References:

	butane-1,3-dithiol
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	24330-52-7
Pubchem (cid):	520119
Pubchem (sid):	135263581

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	HMDB33552
FooDB:	FDB011618
ChemSpider:	View
FAO:	1,3-Butanedithiol