(R)-(+)-menthofuran
benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl-, (R)-
 
Notes:
Constit. of peppermint oil (Mentha piperita) and other Mentha spp. as minor but essential organoleptic. Used in peppermint oil formulations
Synonyms   Articles   Notes   Search
(6R)-3,6-dimethyl-4,5,6,7-tetrahydro-1-benzofuran (Click)
CAS Number: 17957-94-7Picture of molecule
FDA UNII: 9N0IS8189W
Nikkaji Web: J330.675E
Beilstein Number: 0002729
MDL: MFCD00142332
XlogP3-AA: 3.00 (est)
Molecular Weight: 150.22078000
Formula: C10 H14 O
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 210.70 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.300000 mm/Hg @ 25.00 °C. (est)
Flash Point: 168.00 °F. TCC ( 75.60 °C. ) (est)
logP (o/w): 4.020 (est)
Soluble in:
 water, 16.36 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Type: minty
Odor Strength: medium ,
recommend smelling in a 10.00 % solution or less
 minty  leafy  herbal  camphoreous  
Odor Description:
at 10.00 % in dipropylene glycol. 
mint leafy herbal camphoreous
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
(+)-Menthofuran ≥99%
Sigma-Aldrich
For experimental / research use only.
(+)-Menthofuran
analytical standard
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: natural substances and extractives
Recommendation for (R)-(+)-menthofuran usage levels up to:
 not for fragrance use.
 
Recommendation for (R)-(+)-menthofuran flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 442478
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 (6R)-3,6-dimethyl-4,5,6,7-tetrahydro-1-benzofuran
Chemidplus: 0017957947
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: chirality
 (6R)-3,6-dimethyl-4,5,6,7-tetrahydro-1-benzofuran
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 442478
Pubchem (sid): 135257956
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C18025
HMDB (The Human Metabolome Database): HMDB36089
FooDB: FDB014927
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 mint
Search Trop  Picture
 water mint
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl-, (R)-
(6R)-(+)-3,6-dimethyl-4,5,6,7-tetrahydro-1-benzofuran
(6R)-3,6-dimethyl-4,5,6,7-tetrahydro-1-benzofuran
(+)-3,9-epoxy-p-mentha-3,8-diene
p-mentha-3,8-diene, 3,9-epoxy-, (+)-
(1R)-(+)-menthafuran
 menthofuran, (+)-
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: N-Acetyl lysine/glutathione-derived pyrroles as potential ex vivo biomarkers of bioactivated furan-containing compounds.
PubMed: Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.
PubMed: Structure, function, regulation and polymorphism of human cytochrome P450 2A6.
PubMed: Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites.
PubMed: Biosynthesis of menthofuran in Mentha x piperita: stereoselective and mechanistic studies.
PubMed: Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones.
PubMed: Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.
PubMed: (R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6.
PubMed: Contribution of menthofuran to the hepatotoxicity of pulegone: assessment based on matched area under the curve and on matched time course.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2017 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy