calcium sulfate hydrate
sulfuric acid, calcium salt (1:1), dihydrate
used as fertilizer and in construction materials such as bricks, plaster etc; contains 11 components; found as industrial waste.
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calcium;sulfate;dihydrate (Click)
CAS Number: 13397-24-5Picture of molecule
Other: 70513-70-1
FDA UNII: 4846Q921YM
Molecular Weight: 172.17008000
Formula: Ca H4 O6 S
NMR Predictor: Predict (works with chrome or firefox)
Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: white crystalline solid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: abrasives
anticaking agents
binding agents
bleaching agents
opacifying agents
skin conditioning
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BOC Sciences
For experimental / research use only.
Calcium sulfate (Gypsum)
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-human TCLo 194000 mg/m3/10Y-
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 11(10), Pg. 23, 1967.

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Safety in Use Information:
Category: cosmetic agents
Recommendation for calcium sulfate hydrate usage levels up to:
 not for fragrance use.
Recommendation for calcium sulfate hydrate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24928
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0013397245
EPA/NOAA CAMEO: hazardous materials
RTECS: 13397-24-5
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 13397-24-5
Pubchem (cid): 24928
Pubchem (sid): 134989372
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Haz-Map: View
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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 alabaster hydrate
hydrated calcium sulfate
 calcium sulfate hydrate (1:1:2)
 calcium(II) sulfate, dihydrate (1:1:2)
 cocoat T
 crystacal R
 duracal cemen
 gypsum (Ca(SO4).2H2O)
 gypsum stone
 pigment white 25
 sulfuric acid, calcium salt (1:1), dihydrate
 sulfuric acid, calcium(2+) salt, dihydrate
 terra alba
 tiger kencoat
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PubMed: [Development of Clostridium perfringens selective chromogenic medium].
PubMed: Anaerobically digested food waste in compost for Agaricus bisporus and Agaricus subrufescens and its effect on mushroom productivity.
PubMed: Restoration impact of an uncontrolled phosphogypsum dump site on the seasonal distribution of abiotic variables, phytoplankton and zooplankton along the near shore of the south-western Mediterranean coast.
PubMed: Differential growth and yield by canola (Brassica napus L.) and wheat (Triticum aestivum L.) arising from alterations in chemical properties of sandy soils due to additions of fly ash.
PubMed: Current application of β-tricalcium phosphate composites in orthopaedics.
PubMed: Improved microbial quality of buckwheat using antimicrobial solutions in a fluidized bed.
PubMed: Influence of olive oil press cakes on Shiitake culinary-medicinal mushroom, lentinus edodes (Berk.) singer (higher basidiomycetes) fruiting bodies production and effect of their crude polysaccharides on CCRF-CEM cell proliferation.
PubMed: Cation and anion leaching and growth of Acacia saligna in bauxite residue sand amended with residue mud, poultry manure and phosphogypsum.
PubMed: Influence of calcium and silicon supplementation into Pleurotus ostreatus substrates on quality of fresh and canned mushrooms.
PubMed: Efficacy of ε-polylysine, lauric arginate, or acidic calcium sulfate applied sequentially for Salmonella reduction on membrane filters and chicken carcasses.
PubMed: Inhibition of Listeria monocytogenes by food antimicrobials applied singly and in combination.
PubMed: Efficacy of anticoagulant-free alternative bait products against house mice (Mus musculus) and brown rats (Rattus norvegicus).
PubMed: Dangers of bone graft substitutes: lessons from using GeneX.
PubMed: Synergistic inhibition of Listeria monocytogenes in vitro through the combination of octanoic acid and acidic calcium sulfate.
PubMed: EPR-TL correlation studies on Bi co-doped CaSO4:Dy phosphor.
PubMed: Maintaining quality of litchi fruit with acidified calcium sulfate.
PubMed: Antibrowning and antimicrobial properties of sodium acid sulfate in apple slices.
PubMed: Effects of calcium chloride and calcium sulfate in an oral bolus given as a supplement to postpartum dairy cows.
PubMed: Use of chemical sanitizers to reduce microbial populations and maintain quality of whole and fresh-cut cantaloupe.
PubMed: Preservation of cocoa antioxidant activity, total polyphenols, flavan-3-ols, and procyanidin content in foods prepared with cocoa powder.
PubMed: Radiological impact of almost a century of phosphate industry in Flanders, Belgium.
PubMed: The cumulative effect of three decades of phosphogypsum amendments in reclaimed marsh soils from SW Spain: (226)Ra, (238)U and Cd contents in soils and tomato fruit.
PubMed: Articular cartilage repair using a resorbable matrix scaffold.
PubMed: Effect of filler content and size on transport properties of water vapor in PLA/calcium sulfate composites.
PubMed: Biotransformation of phosphogypsum on distillery decoctions (Preliminary results).
PubMed: Inactivation of enterohemorrhagic Escherichia coli in rumen content- or feces-contaminated drinking water for cattle.
PubMed: Reduction of Campylobacter jejuni on chicken wings by chemical treatments.
PubMed: Chemical and physical changes following co-composting of beef cattle feedlot manure with phosphogypsum.
PubMed: Radon exhalation from phosphogypsum building boards: symmetry constraints, impermeable boundary conditions and numerical simulation of a test case.
PubMed: Viability of Listeria monocytogenes on commercially-prepared hams surface treated with acidic calcium sulfate and lauric arginate and stored at 4°C.
PubMed: Prediction of potential mushroom yield by visible and near-infrared spectroscopy using fresh phase II compost.
PubMed: The effect of phosphogypsum on greenhouse gas emissions during cattle manure composting.
PubMed: In vitro binding of zearalenone to different adsorbents.
PubMed: Uptake of iron by a vegetable; kaiware daikon (Japanese radish sprout).
PubMed: Influence of freezing and freezing plus acidic calcium sulfate and lactic acid addition on thermal inactivation of Escherichia coli O157:H7 in ground beef.
PubMed: Enhancement of tofu isoflavone recovery by pretreatment of soy milk with koji enzyme extract.
PubMed: Effects of applying Safe2O poultry wash to broiler wings on shelf life, Listeria monocytogenes, Pseudomonads, Staphylococcus species, and psychrotrophic bacteria levels after three, seven, and ten days of storage.
PubMed: Effectiveness of acidic calcium sulfate with propionic and lactic acid and lactates as postprocessing dipping solutions to control Listeria monocytogenes on frankfurters with or without potassium lactate and stored vacuum packaged at 4.5 degrees C.
PubMed: The effect of sulfur fertilizer on glucoraphanin levels in broccoli (B. oleracea L. var. italica) at different growth stages.
PubMed: Viability of acid-adapted Escherichia coli O157:H7 in ground beef treated with acidic calcium sulfate.
PubMed: Effect of calcium sulfate concentration in soymilk on the microstructure of firm tofu and the protein constitutions in tofu whey.
PubMed: Calcium absorption from three salts and CaSO(4)-fortified bread in premenopausal women.
PubMed: The debate over the pathogenic nature of plastered wine.
PubMed: Preparation of bean curds from protein fractions of six legumes.
PubMed: Mechanical properties and water-vapor permeability of soy-protein films affected by calcium salts and glucono-delta-lactone.
PubMed: Use of bone-graft substitutes in distal radius fractures.
PubMed: Inhibition of sulfate reduction to sulfide by 9,10-anthraquinone in in vitro ruminal fermentations.
PubMed: The physiological property and function of the electrolyzed-ionized calcium Aquamax on water molecular clusters fractionization.
PubMed: Possible relationship of succinate dehydrogenase and fatty acid synthetase activities to Aspergillus parasiticus (NRRL 5139) growth and aflatoxin production.
PubMed: Laying hens respond differently to high dietary levels of phosphorus in monobasic and dibasic calcium phosphate.
PubMed: Calcium carbonate depresses iron bioavailability in rats more than calcium sulfate or sodium carbonate.
PubMed: A novel human hepatoblastoma cell line (HuH-6KK) with rapid growth in serum-free medium without extracellular matrix.
PubMed: Radioecological model calculations for natural radionuclides released into the environment by disposal of phosphogypsum.
PubMed: Bread (white and whole wheat) and nonfat dry milk as sources of bioavailable calcium for rats.
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