diisopropyl sebacate
vehicle in topical anti-acne lotion; implicated in contact dermatitis.
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dipropan-2-yl decanedioate (Click)
CAS Number: 7491-02-3
ECHA EINECS - REACH Pre-Reg: 231-306-4
Nikkaji Web: J26.295A
XlogP3-AA: 4.40 (est)
Molecular Weight: 286.41190000
Formula: C16 H30 O4
NMR Predictor: Predict
Category: solvents/deluents for cosmetic and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 307.00 to  309.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.001000 mm/Hg @ 25.00 °C. (est)
Flash Point: 275.00 °F. TCC ( 134.90 °C. ) (est)
logP (o/w): 4.627 (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: emollients
skin conditioning
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Alzo International
Dermol DIPS
Chemical-navi - Nikkol
Odor: characteristic
Use: Dibasic acid ester; good solubility and penetration; light feel; penetrating agent for topical drug forms.
Lubrizol Corporation
Schercemol™ DIS Ester
Odor: charateristic
Use: Schercemol DIS ester has rapid absorbency and fast spreading. Schercemol DIS ester demonstrates excellent compatibility in hydro-alcoholic cosmetic formulations, and is commonly used in electric pre-shave and after-shave lotions. Additional applications include men's grooming aids and hand lotions.
Stearinerie Dubois
Universal Preserv-A-Chem Inc.
Odor: characteristic
Use: JEECHEM DIS demonstrates excellent compatibility in hydro-alcoholic cosmetic formulations. Typical uses for JEECHEM DIS in hydro-alcoholic products are special face lotions, where it functions as a non-oily emollient lubricant with mild drying effects. Aside from the superior mutual solvent and coupling agent properties, JEECHEM DIS is an outstanding cosmetic emollient with wide and fast spreading action, permitting its use in bath oils: frequently, in combination with mineral oil and other esters. Additionally, it is used in lip products, men-s grooming aids and hand lotions.
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: solvents/deluents for cosmetic and fragrance agents
Recommendation for diisopropyl sebacate usage levels up to:
 not for fragrance use.
Recommendation for diisopropyl sebacate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Chemicalize.org: Calculate predicted properties
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 7491-02-3
EPA ACToR: Toxicology Data
National Institute of Allergy and Infectious Diseases: Data
 dipropan-2-yl decanedioate
Chemidplus: 0007491023
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 dipropan-2-yl decanedioate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7491-02-3
Pubchem (cid): 24096
Pubchem (sid): 134987562
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Household Products: Search
ChemSpider: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Natural Occurrence in: note
 not found in nature
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 decane dioic acid diisopropyl ester
 decanedioic acid bis(1-methylethyl) ester
 decanedioic acid, 1,10-bis(1-methylethyl) ester
 decanedioic acid, bis(1-methylethyl) ester
 dermol DIPS
 dipropan-2-yl decanedioate
 nikkol DIS
 schercemol DIS ester
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click on the picture(s) below to
interact with the 3D model
Picture of molecule
Soluble in:
 water, 0.5672 mg/L @ 25 °C (est)
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