EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

squalane
tetracosane, 2,6,10,15,19,23-hexamethyl-

Supplier Sponsors

CAS Number: 111-01-3Picture of molecule3D/inchi
Other(deleted CASRN):2101721-37-1
ECHA EINECS - REACH Pre-Reg:203-825-6
FDA UNII: GW89575KF9
Nikkaji Web:J1.982H
Beilstein Number:0776019
MDL:MFCD00008953
XlogP3-AA:14.70 (est)
Molecular Weight:422.82414000
Formula:C30 H62
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.81000 @ 25.00 °C.
Melting Point: -38.00 °C. @ 760.00 mm Hg
Boiling Point: 350.00 °C. @ 760.00 mm Hg
Boiling Point: 210.00 to 215.00 °C. @ 1.00 mm Hg
Flash Point: 424.00 °F. TCC ( 217.78 °C. )
logP (o/w): 15.057 (est)
Soluble in:
 water, 2.042e-010 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
refatting agents
skin conditioning
skin conditioning - emollient
 
Suppliers:
American International Chemical, LLC.
Squalene
BOC Sciences
For experimental / research use only.
2,6,10,15,19,23-Hexamethyltetracosane >98.0%(GC)
Camden-Grey Essential Oils
Squalane, olive oil derived
Odor: characteristic
Use: Squalane is chemically inert material that is a normal constituent of the human sebum. Since Squalane is naturally-occurring in man and is non-toxic, non-irritating, hypoallergenic and non-sensitizing, it is an ideal natural emollient.
Charkit Chemical
SQUALANE, OLIVE COSMETIC
Charkit Chemical
SQUALANE, SYNTHETIC
Charkit Chemical
SQUALENE, NATURAL, FOOD GRADE
Charkit Chemical
SQUALENE, OLIVE
Chemical-navi - Nikkol
NIKKOL Olive Squalane
Odor: characteristic
Use: Hydrogenated squalene from olive; plant origin; good spreadability and lubricity; superior stability.
Chemical-navi - Nikkol
NIKKOL SQUALANE
ECSA Chemicals
SQUALANE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Mosselman
Perhydrosqualene
Penta International
SQUALANE NATURAL (Olive Derived)
Penta International
SQUALANE NF
Santa Cruz Biotechnology
For experimental / research use only.
Squalane
Sigma-Aldrich: Aldrich
For experimental / research use only.
Squalane 99%
TCI AMERICA
For experimental / research use only.
Squalane >98.0%(GC)
TRI-K Industries
OleaClear Olive Squalane
Odor: characteristic
Use: OleaClear Olive Squalane is a plant derived squalane that functions as an emollient for topical applications in creams, lotions, ointments,lipsticks, and other cosmetics.
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for squalane usage levels up to:
 not for fragrance use.
 
Recommendation for squalane flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):111-01-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8089
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2,6,10,15,19,23-hexamethyltetracosane
Chemidplus:0000111013
RTECS:XB6070000 for cas# 111-01-3
 
References:
 2,6,10,15,19,23-hexamethyltetracosane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:111-01-3
Pubchem (cid):8089
Pubchem (sid):134974712
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):D05915
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2901.10.5000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 emollients
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 cosbiol
 dodecahydrosqualene
2,6,10,15,19,23-hexamethyl tetracosane
2,6,10,15,19,23-hexamethyltetracosane
 nikkol olive squalane
 nikkol squalane
 oleaclear olive squalane
 oleox
 perhydrosqualene
 pripure 3759
 spinacane
oleaclear olive squalane
 squalane cosmetic 97.9% spain
 squalane NF
 squalane olifeel SQ-H
 squalane, olive oil derived
 squalene, perhydro-
 tetracosane, 2,6,10,15,19,23-hexamethyl-
 vitabiosol
 

Articles:

PubMed:Fullerene-C60 derivatives prevent UV-irradiation/ TiO2-induced cytotoxicity on keratinocytes and 3D-skin tissues through antioxidant actions.
PubMed:Dry oil powders and oil foams stabilised by fluorinated clay platelet particles.
PubMed:OH-initiated heterogeneous oxidation of internally-mixed squalane and secondary organic aerosol.
PubMed:Diffusion of squalene in n-alkanes and squalane.
PubMed:Structure and friction of stearic acid and oleic acid films adsorbed on iron oxide surfaces in squalane.
PubMed:Effect of monoglyceride structure and cholesterol content on water permeability of the droplet bilayer.
PubMed:Combination of ERG9 Repression and Enzyme Fusion Technology for Improved Production of Amorphadiene in Saccharomyces cerevisiae.
PubMed:Disintegration and cancer immunotherapy efficacy of a squalane-in-water delivery system emulsified by bioresorbable poly(ethylene glycol)-block-polylactide.
PubMed:Site and bond-specific dynamics of reactions at the gas-liquid interface.
PubMed:Dielectric relaxation of long-chain glass-forming monohydroxy alcohols.
PubMed:Organic aerosol mixing observed by single-particle mass spectrometry.
PubMed:Solution properties and emulsification properties of amino acid-based gemini surfactants derived from cysteine.
PubMed:Inelastic scattering of OH radicals from organic liquids: isolating the thermal desorption channel.
PubMed:Colloidal luminescent silicon nanorods.
PubMed:Preparation and physicochemical properties of surfactant-free emulsions using electrolytic-reduction ion water containing lithium magnesium sodium silicate.
PubMed:Systemically administered gp100 encoding DNA vaccine for melanoma using water-in-oil-in-water multiple emulsion delivery systems.
PubMed:A statistical description of the evolution of cloud condensation nuclei activity during the heterogeneous oxidation of squalane and bis(2-ethylhexyl) sebacate aerosol by hydroxyl radicals.
PubMed:Determinations of gas-liquid partition coefficients using capillary chromatographic columns. Alkanols in squalane.
PubMed:The influence of molecular structure and aerosol phase on the heterogeneous oxidation of normal and branched alkanes by OH.
PubMed:Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model.
PubMed:Interfacial tension dynamics, interfacial mechanics, and response to rapid dilution of bulk surfactant of a model oil-water-dispersant system.
PubMed:Formulated squalene for food related applications.
PubMed:Observation of rates and products in the reaction of NO3 with submicron squalane and squalene aerosol.
PubMed:Anomalous diffusion kinetics of the precursor film that spreads from polymer droplets.
PubMed:How membrane permeation is affected by donor delivery solvent.
PubMed:Optimization of cell-wall skeleton derived from Mycobacterium bovis BCG Tokyo 172 (SMP-105) emulsion in delayed-type hypersensitivity and antitumor models.
PubMed:Multi-compartmental vaccine delivery system for enhanced immune response to gp100 peptide antigen in melanoma immunotherapy.
PubMed:Long-living structures of photochromic salicylaldehyde azine: polarity and viscosity effects from nanoseconds to hours.
PubMed:Reverse vesicle formation from the yeast glycolipid biosurfactant mannosylerythritol lipid-D.
PubMed:OH-initiated heterogeneous aging of highly oxidized organic aerosol.
PubMed:A cinnamic acid-type photo-cleavable surfactant.
PubMed:Biological importance and applications of squalene and squalane.
PubMed:Electron paramagnetic resonance line shifts and line shape changes due to heisenberg spin exchange and dipole-dipole interactions of nitroxide free radicals in liquids 8. Further experimental and theoretical efforts to separate the effects of the two interactions.
PubMed:Structural control of nanocrystal superlattices using organic guest molecules.
PubMed:The statistical evolution of multiple generations of oxidation products in the photochemical aging of chemically reduced organic aerosol.
PubMed:Chemical characterization and source apportionment of fine and coarse particulate matter inside the refectory of Santa Maria Delle Grazie Church, home of Leonardo Da Vinci's "Last Supper".
PubMed:Surfactant-free, large-scale, solution-liquid-solid growth of gallium phosphide nanowires and their use for visible-light-driven hydrogen production from water reduction.
PubMed:Predicting the wetting dynamics of a two-liquid system.
PubMed:Preparation of a solid-in-oil nanosuspension containing L-ascorbic acid as a novel long-term stable topical formulation.
PubMed:Diffusion of organic solutes in squalane.
PubMed:Complete synthesis of germanium nanocrystal encrusted carbon colloids in supercritical CO2 and their superhydrophobic properties.
PubMed:Can we predict the spreading of a two-liquid system from the spreading of the corresponding liquid-air systems?
PubMed:Large amplitude oscillatory shear of block copolymer spheres on a body-centered cubic lattice: are micelles like metals?
PubMed:Potentially important nighttime heterogeneous chemistry: NO3 with aldehydes and N2O5 with alcohols.
PubMed:Dynamic QM/MM: a hybrid approach to simulating gas-liquid interactions.
PubMed:Dynamics of the gas-liquid interfacial reaction of O(1D) with a liquid hydrocarbon.
PubMed:The direct observation of secondary radical chain chemistry in the heterogeneous reaction of chlorine atoms with submicron squalane droplets.
PubMed:Collision dynamics and reactive uptake of OH radicals at liquid surfaces of atmospheric interest.
PubMed:Interaction of 1,3,2,4-benzodithiadiazines and their 1-Se congeners with Ph3P and some properties of the iminophosphorane products.
PubMed:Reactive uptake kinetics of NO3 on multicomponent and multiphase organic mixtures containing unsaturated and saturated organics.
PubMed:Nanoscale mixing of soft solids.
PubMed:Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.
PubMed:A stochastic, local mode study of neon-liquid surface collision dynamics.
PubMed:Comparison of the mobilities of negative and positive ions in nonpolar solutions.
PubMed:Defensive effects of fullerene-C60 dissolved in squalane against the 2,4-nonadienal-induced cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue model.
PubMed:Stable isotope ratios of carbon and hydrogen to distinguish olive oil from shark squalene-squalane.
PubMed:The effect of squalane-dissolved fullerene-C60 on adipogenesis-accompanied oxidative stress and macrophage activation in a preadipocyte-monocyte co-culture system.
PubMed:Activation energy of the two-proton phototautomerism in 7-azaindole dimer and its medium-dependence.
PubMed:O(3P) atoms as a chemical probe of surface ordering in ionic liquids.
PubMed:Compositional ripening of particle- and surfactant-stabilised emulsions: a comparison.
PubMed:Ambient analysis of saturated hydrocarbons using discharge-induced oxidation in desorption electrospray ionization.
PubMed:Squalene emulsions for parenteral vaccine and drug delivery.
PubMed:Measurement of fragmentation and functionalization pathways in the heterogeneous oxidation of oxidized organic aerosol.
PubMed:Quantifying the reactive uptake of OH by organic aerosols in a continuous flow stirred tank reactor.
PubMed:Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor.
PubMed:Phase behavior, formation, and rheology of cubic phase and related gel emulsion in Tween 80/water/oil systems.
PubMed:Effects of temperature on water-in-oil emulsions stabilised solely by wax microparticles.
PubMed:Liquid Spreading under Nanoscale Confinement.
PubMed:Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.
PubMed:Collisions of DCl with a solution covered with hydrophobic and hydrophilic ions: tetrahexylammonium bromide in glycerol.
PubMed:Modeling reactive scattering of F(2P) at a liquid squalane interface: a hybrid QM/MM molecular dynamics study.
PubMed:Structure of poly(styrene-b-ethylene-alt-propylene) diblock copolymer micelles in squalane.
PubMed:Dynamics of the reaction of O(3P) atoms with alkylthiol self-assembled monolayers.
PubMed:From protons to OXPHOS supercomplexes and Alzheimer's disease: structure-dynamics-function relationships of energy-transducing membranes.
PubMed:Quantum-state resolved reactive scattering at the gas-liquid interface: F+squalane (C30H62) dynamics via high-resolution infrared absorption of nascent HF(v,J).
PubMed:Monitoring of technical oils in supercritical CO(2) under continuous flow conditions by NIR spectroscopy and multivariate calibration.
PubMed:[Innovation of vaccine adjuvants].
PubMed:Hexagonal phase based gel-emulsion (O/H1 gel-emulsion): formation and rheology.
PubMed:Semi-empirical topological index: development of QSPR/QSRR and optimization for alkylbenzenes.
PubMed:Lipid biomarker and phylogenetic analyses to reveal archaeal biodiversity and distribution in hypersaline microbial mat and underlying sediment.
PubMed:Enhanced mucosal and systemic immune response with squalane oil-containing multiple emulsions upon intranasal and oral administration in mice.
PubMed:Solution-liquid-solid (SLS) growth of silicon nanowires.
PubMed:Squeeze-out of branched alkanes on graphite.
PubMed:New contributions to the photophysical model for all-trans-polyenes from ttbP4, a nonphotolabile octatetraene.
PubMed:Apparent and true enantioselectivity of single- and binary-selector chiral stationary phases in gas chromatography.
PubMed:The EACN scale for oil classification revisited thanks to fish diagrams.
PubMed:Reduction of dioxins and polychlorinated biphenyls (PCBs) in human body.
PubMed:Effect of water on foaming properties of diglycerol fatty acid ester-oil systems.
PubMed:Theoretical investigation of hyperthermal reactions at the gas-liquid interface: O (3P) and squalane.
PubMed:Three-dimensional topographic index applied to the prediction of acyclic C5-C8 alkenes Kováts retention indices on polydimethylsiloxane and squalane columns.
PubMed:Mild TiIII- and Mn/ZrIV-catalytic reductive coupling of allylic halides: efficient synthesis of symmetric terpenes.
PubMed:Comparative study of normal and branched alkane monolayer films adsorbed on a solid surface. II. Dynamics.
PubMed:Comparative study of normal and branched alkane monolayer films adsorbed on a solid surface. I. Structure.
PubMed:Wetting and electrical properties of the human hair surface: delipidation observed at the nanoscale.
PubMed:Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure.
PubMed:Foaming properties of monoglycerol fatty acid esters in nonpolar oil systems.
PubMed:Friction laws for lubricated nanocontacts.
PubMed:Microemulsions of triglyceride-based oils: The effect of co-oil and salinity on phase diagrams.
PubMed:Entropy-enthalpy compensations in solutions of dual character molecules with polymeric chromatographic liquid phases.
PubMed:Quantum-state resolved reaction dynamics at the gas-liquid interface: direct absorption detection of HF(v,J) product from F(2P)+squalane.
PubMed:Intramolecular dynamics of 1,2,3-trifluorobenzene radical anions as studied by OD ESR and quantum-chemical methods.
PubMed:Sucrose fatty acid sulphate esters as novel vaccine adjuvant.
PubMed:Hyperthermal reactions of O and O2 with a hydrocarbon surface: direct C-C bond breakage by O and H-atom abstraction by O2.
PubMed:Phase behavior of monoglycerol fatty acid esters in nonpolar oils: reverse rodlike micelles at elevated temperatures.
PubMed:Molecular dynamics study to identify the reactive sites of a liquid squalane surface.
PubMed:A colloidal ZnO/Cu nanocatalyst for methanol synthesis.
PubMed:Nonionic ortho ester surfactants as cleavable emulsifiers.
PubMed:Direct gas-liquid interfacial dynamics: the reaction between O(3P) and a liquid hydrocarbon.
PubMed:Phase behavior of diglycerol fatty acid esters-nonpolar oil systems.
PubMed:Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies.
PubMed:Diluent effects on the Debye-type dielectric relaxation in viscous monohydroxy alcohols.
PubMed:Localization of coenzyme Q10 in the center of a deuterated lipid membrane by neutron diffraction.
PubMed:Study of sensory properties of emollients used in cosmetics and their correlation with physicochemical properties.
PubMed:Silver halide fiber-based evanescent-wave liquid droplet sensing with room temperature mid-infrared quantum cascade lasers.
PubMed:Discrete solvation layering in confined binary liquids.
PubMed:[Molecular topology study of gas chromatographic retention indices of alkane series].
PubMed:Further studies on the effect of degassing on the dispersion and stability of surfactant-free emulsions.
PubMed:Wetting of surfactant solutions by alkanes.
PubMed:Distributions of C22-C30 even-carbon-number n-alkanes in Ocean Anoxic Event 1 samples from the Basque-Cantabrian Basin.
PubMed:[The study of relation of the retention indices of n-alkenes with their molecular structure].
PubMed:Physicochemical characterization and gene transfection efficiency of lipid emulsions with various co-emulsifiers.
PubMed:The effects of surface temperature on the gas-liquid interfacial reaction dynamics of O(3P)+squalane.
PubMed:Synthesis, characterization and transfection activity of new saturated and unsaturated cationic lipids.
PubMed:Sucrose fatty acid sulphate esters as novel vaccine adjuvants: effect of the chemical composition.
PubMed:Role of alpha-methylacyl coenzyme A racemase in the degradation of methyl-branched alkanes by Mycobacterium sp. strain P101.
PubMed:Superlubricity: a paradox about confined fluids resolved.
PubMed:Predictive relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles.
PubMed:Spectroscopy of the conformational disorder in molecular films: tetracosane and squalane on Pt(111).
PubMed:Preparation and evaluation of multiple emulsions water-in-oil-in-water (w/o/w) as delivery system for influenza virus antigens.
PubMed:Capillary gas chromatography-mass spectrometry of all 93 acyclic octenes and their identification in fluid catalytic cracked gasoline.
PubMed:The interaction of monosubstituted benzenes with the stationary liquid in gas liquid chromatography.
PubMed:Transitions between smooth and complex stick-slip sliding of surfaces.
PubMed:Alkanindiges illinoisensis gen. nov., sp. nov., an obligately hydrocarbonoclastic, aerobic squalane-degrading bacterium isolated from oilfield soils.
PubMed:Radical cage effects in the photochemical degradation of polymers: effect of radical size and mass on the cage recombination efficiency of radical cage pairs generated photochemically from the (CpCH2CH2N(CH3)C(O)(CH2)nCH3)2Mo2(CO)6 (n = 3, 8, 18) complexes.
PubMed:Remediation of contaminated soil by a solvent/surfactant system.
PubMed:Reactor design and kinetics study of 4,4'-dichlorobiphenyl photodecay in surfactant solution by using a photosensitizer and hydrogen source.
PubMed:[Analysis of C5 fractions and carbonyl compounds by capillary gas chromatography].
PubMed:[Investigation on the changing regularity of the relationship between retention index and temperature of the GDX series stationary phases].
PubMed:Structure of three new terpenoids, spiciformisins a and b, and monocyclosqualene, isolated from the herbs of Ligularia fischeri var. spiciformis and cytotoxicity.
PubMed:Squalane is in the midplane of the lipid bilayer: implications for its function as a proton permeability barrier.
PubMed:Inhibitory effect of BCG cell-wall skeletons (BCG-CWS) emulsified in squalane on tumor growth and metastasis in mice.
PubMed:Molecular simulation of concurrent gas-liquid interfacial adsorption and partitioning in gas-liquid chromatography.
PubMed:Protection by methyl inosine monophosphate (MIMP) against aerosol influenza virus infection in mice.
PubMed:Molecular cloning of a vaccine antigen against infection with the larval stage of Echinococcus multilocularis.
PubMed:Solvation forces in branched molecular liquids.
PubMed:Temperature effects on the retention of n-alkanes and arenes in helium-squalane gas-liquid chromatography. Experiment and molecular simulation.
PubMed:Gas chromatographic-mass spectrometric characterization of all acyclic C5-C7 alkenes from fluid catalytic cracked gasoline using polydimethylsiloxane and squalane stationary phases.
PubMed:Comparison of nonequilibrium molecular dynamics with experimental measurements in the nonlinear shear-thinning regime.
PubMed:Influence of analyte overloading on retention in gas-liquid chromatography: a molecular simulation view.
PubMed:Conjugated triene oxidation products of alpha-farnesene induce symptoms of superficial scald on stored apples.
PubMed:Dynamic phase transitions in confined lubricant fluids under shear.
PubMed:Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells.
PubMed:Positional effect of solute functional group among positional isomers in hydroxyl group-solvent and carbonyl group-solvent specific interactions in menthanol--water mixed solvents monitored by high-performance liquid chromatography.
PubMed:Chromatographic methods for the determination of the logL16 solute descriptor.
PubMed:Gas chromatographic study of the hydrogen bonding of aliphatic alcohols to tri-n-octylphosphine oxide.
PubMed:Processes of luminescence quenching in study of molecular oxygen diffusion in glassy matrices.
PubMed:Induction and detection of antibodies to squalene.
PubMed:Microbial degradation of the multiply branched alkane 2,6,10,15,19, 23-hexamethyltetracosane (Squalane) by Mycobacterium fortuitum and Mycobacterium ratisbonense.
PubMed:Adjuvant effects of sulfolipo-cyclodextrin in a squalane-in-water and water-in-mineral oil emulsions for BHV-1 vaccines in cattle.
PubMed:The preventive effects of incomplete Freund's adjuvant and other vehicles on the development of adjuvant-induced arthritis in Lewis rats.
PubMed:Squalene and squalane emulsions as adjuvants.
PubMed:Sulfolipo-cyclodextrin in squalane-in-water as a novel and safe vaccine adjuvant.
PubMed:Effect of various adjuvants on secondary immune response in chickens.
PubMed:Quantitative analysis of a synthetic adjuvant by an immunoassay.
PubMed:Microdynamics and phase equilibria in organic nanocrystals.
PubMed:Immunopotentiation of humoral and cellular responses to inactivated influenza vaccines by two different adjuvants with potential for human use.
PubMed:The mode of action of immunological adjuvants.
PubMed:A Model for Detachment of a Partially Wetting Drop from a Solid Surface by Shear Flow
PubMed:Inactivated vaccine for protection against duck virus enteritis.
PubMed:Evaluation of heterotopic bone formation induced by squalane and bone morphogenetic protein composite.
PubMed:Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel.
PubMed:Comparison of linear and branched peptide forms (MAPs) in the induction of T helper responses to point-mutated ras immunogens.
PubMed:Solid phase microextraction for quantitative headspace sampling of apple volatiles.
PubMed:Cytokines and antibody subclass associated with protective immunity against blood-stage malaria in mice vaccinated with the C terminus of merozoite surface protein 1 plus a novel adjuvant.
PubMed:Solvent-Augmented Mineralization of Pyrene by a Mycobacterium sp.
PubMed:A novel adjuvant for use with a blood-stage malaria vaccine.
PubMed:The induction of cytotoxic T cells and tumor regression by soluble antigen formulation.
PubMed:Effect of vehicles on diclofenac permeation across excised rat skin.
PubMed:Determination and use of Rohrschneider-McReynolds constants for chiral stationary phases used in capillary gas chromatography.
PubMed:Electron impact mass spectrometry of alkanes in supersonic molecular beams.
PubMed:Induction of a CD8+ cytotoxic T lymphocyte response to soluble antigen given together with a novel muramyl dipeptide adjuvant, N-acetyl-D-glucosaminyl-(beta 1-4)-N-acetylmuramyl-L-alanyl-D-isoglutamine (GMDP).
PubMed:Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant.
PubMed:The influence of surface properties on uptake of oil into complex coacervate microcapsules.
PubMed:Squalene metabolism in two species of Lagenidium.
PubMed:A novel non-mineral oil-based adjuvant. II. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in pigs.
PubMed:A novel non-mineral oil-based adjuvant. I. Efficacy of a synthetic sulfolipopolysaccharide in a squalane-in-water emulsion in laboratory animals.
PubMed:Adjuvants and immune enhancement.
PubMed:Induction of cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein by immunization with soluble recombinant protein without adjuvant.
PubMed:Squalane as a possible carrier of bone morphogenetic protein.
PubMed:[Stimulating effect of dietary fiber on fecal excretion of polychlorinated dibenzofurans (PCDF) and polychlorinated dibenzo-p-dioxins (PCDD) in rats].
PubMed:The control of the antibody isotype response to recombinant human immunodeficiency virus gp120 antigen by adjuvants.
PubMed:Induction of antigen-specific class I-restricted cytotoxic T cells by soluble proteins in vivo.
PubMed:Enhanced elimination of theophylline, phenobarbital and strychnine from the bodies of rats and mice by squalane treatment.
PubMed:Direct quantitative digital autoradiography-thin-layer chromatography of 3 alpha,3 beta- and 5 alpha-reduced and 17 beta-dehydrogenated androgens derived from testosterone metabolism.
PubMed:Immunogenicity of Streptococcus pneumoniae type 14 capsular polysaccharide: influence of carriers and adjuvants on isotype distribution.
PubMed:Stereographic and stereometric study of sebaceous gland hyperplasia in rabbit pinnas induced by topically applied substances.
PubMed:Molecular beam scattering from liquid surfaces.
PubMed:Stratum corneum lipids serve as a bound-water modulator.
PubMed:Use of adjuvant containing mycobacterial cell-wall skeleton, monophosphoryl lipid A, and squalane in malaria circumsporozoite protein vaccine.
PubMed:[Studies on distribution and excretion of squalane in dogs administered for 2 weeks].
PubMed:Adjuvant activity of non-ionic block copolymers. V. Modulation of antibody isotype by lipopolysaccharides, lipid A and precursors.
PubMed:Immunological adjuvants: desirable properties and side-effects.
PubMed:In vitro transport of sodium diclofenac across rat abdominal skin: effect of selection of oleaginous component and the addition of alcohols to the vehicle.
PubMed:Use of adjuvants in modulating the behaviour of Plasmodium berghei.
PubMed:Efficacy of experimental Newcastle disease water-in-oil oil-emulsion vaccines formulated from squalane and squalene.
PubMed:Adjuvant formulations and their mode of action.
PubMed:Formulation of vaccine adjuvant muramyldipeptides. 3. Processing optimization, characterization, and bioactivity of an emulsion vehicle.
PubMed:Validation of a first-generation Epstein-Barr virus vaccine preparation suitable for human use.
PubMed:Lethal toxicity and adjuvant activities of synthetic TDM and its related compounds in mice.
PubMed:[Studies on distribution, excretion and subacute toxicity of squalane in dogs].
PubMed:[Histological study on the gingiva in PenCB poisoned beagle dogs].
PubMed:[Histopathology of meibomian gland abnormalities in experimental PenCB intoxicated beagle treated with squalane].
PubMed:Biomedical applications of chromatographic fraction containing trehalose dimycolate in squalane emulsion.
PubMed:Alamethicin adsorption to a planar lipid bilayer.
PubMed:Adjuvant formulation for use in vaccines to elicit both cell-mediated and humoral immunity.
PubMed:Thermochemical investigations of associated solutions: 4. Calculation of carbazole-dibutyl ether association constants from measured solubility in binary solvent mixtures.
PubMed:[Studies on the therapeutic effect of squalane on symptoms of PCDFs poisoning in monkeys].
PubMed:Pulse circulation gas chromatography on capillary columns.
PubMed:Modulation of natural killer cytotoxicity by muramyl dipeptide and trehalose dimycolate incorporated in squalane droplets.
PubMed:Selective recovery of deranged water-holding properties by stratum corneum lipids.
PubMed:Antitumor effect of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha,alpha-trehalose (SS554), in mice.
PubMed:[Antitumor effect of a synthetic cord factor, 6,6'-di-O-decanoyl-alpha, alpha-trehalose (SS 554) in mice].
PubMed:Adjuvant and antitumour activities of synthetic lipid A analogues.
PubMed:Immunobiological activities of nontoxic lipid A: enhancement of nonspecific resistance in combination with trehalose dimycolate against viral infection and adjuvant effects.
PubMed:Antitumor activity on line 10 hepatoma in strain 2 guinea pigs and pharmaceutical properties of quinonyl-MDP preparations.
PubMed:Stimulation of faecal excretion of hexachlorobenzene: a review.
PubMed:Ambivalent properties of gold drugs in adjuvant induced polyarthritis in rats.
PubMed:The influence of n-alkanols on the capacity per unit area of planar lipid bilayers.
PubMed:Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxides.
PubMed:Stimulation of the faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl in rats by squalane.
PubMed:Regression of line-10 hepatocarcinoma with synthetic quinonyl muramyl dipeptide in strain-2 guinea pigs.
PubMed:Local muscle damage and oily vehicles: a study on local reactions in rabbits after intramuscular injection of neuroleptic drugs in aqueous or oily vehicles.
PubMed:Photon correlation spectroscopy of bilayer lipid membranes.
PubMed:Effects of dietary paraffin, squalane and sucrose polyester on residue disposition and elimination of hexachlorobenzene in rats.
PubMed:Eradication by active specific immunotherapy of established tumor transplants and microscopic lymph node metastases.
PubMed:The influence of n-alkanols and cholesterol on the duration and conductance of gramicidin single channels in monoolein bilayers.
PubMed:The effect of squalane on the absorption of dietary cholesterol by the rat.
PubMed:Effect of squalane on hexachlorobenzene (HCB) concentrations in tissues of mice.
PubMed:Excretion of beta-hexachlorocyclohexane by the rat as influenced by oral paraffin, squalane, and Lutrol E 400.
PubMed:Persistent enhancement of cell-mediated and antibody immune responses after administration of muramyl dipeptide derivatives with antigen in metabolizable oil.
PubMed:Intestinal excretion of hexachlorobenzene.
PubMed:Specific acyclic isoprenoids as biological markers of methanogenic bacteria in marine sediments.
PubMed:Immunotherapy of experimental cancer with a mixture of synthetic muramyl dipeptide and trehalose dimycolate.
PubMed:Metabolism of beta-hexachlorocyclohexane-14C in rats following low dosing in the daily diet.
PubMed:Presence of squalane in urban aquatic environments.
PubMed:Influence of type of oil and surfactant concentration on the efficacy of emulsified Mycobacterium bovis BCG cell walls to induce tumor regression in guinea pigs.
PubMed:Susceptibility to adjuvant-induced arthritis among germfree, specific-pathogen-free, and conventional rats.
PubMed:Regression of a murine fibrosarcoma after intralesional injection of a synthetic C39 glycolipid related to cord factor.
PubMed:The interaction of n-octanol with black lipid bilayer membranes.
PubMed:Ageing of columns of homogeneous mixed stationary phases in gas chromatography.
PubMed:Tumor regression after intralesional injection of mycobacterial components emulsified in 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene (squalene), 2,6,10,15,19,23-hexamethyltetracosane (squalane), peanut oil, or mineral oil.
PubMed:Effect of oil composition on both adjuvant-induced arthritis and delayed hypersensitivity to purified protein derivative and peptidoglycans in various rat strains.
PubMed:Arthritogenicity of wax D from various mycobacteria related to oil vehicle composition and to the combination with poly I:C, cord factor and acetylated wax D.
PubMed:Analytical aspects of capillary gas chromatography of lower fatty acids [up to C18].
PubMed:Arthritogenicity of Mycobacterium smegmatis subfractions, related to different oil vehicle and different composition.
PubMed:Separation of monosubstituted phenols by gas-liquid chromatography.
PubMed:A comprehensive study of isomeric butylbenzenes by gas-liquid chromatography.
 
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