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ethyl acrylate
acrylic acid, ethyl ester

Supplier Sponsors

Flavor Demo Formulas
Name:ethyl prop-2-enoate
CAS Number: 140-88-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-438-8
FDA UNII:71E6178C9T
Nikkaji Web:J2.534H
Beilstein Number:0773866
MDL:MFCD00009188
CoE Number:245
XlogP3:1.30 (est)
Molecular Weight:100.11716000
Formula:C5 H8 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:food contact acrylic and modified acrylic plastics
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1977 Monomeric ethyl acrylate (packaging) View-review
JECFA Food Flavoring:1351 ethyl acrylate
FLAVIS Number:09.037 (Old)
DG SANTE Food Flavourings:09.037 ethyl acrylate
DG SANTE Food Contact Materials:ethyl acrylate
FEMA Number:2418-VOID ethyl acrylate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):140-88-5 ; ETHYL ACRYLATE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.




FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.320 Resinous and polymeric coatings for polyolefin films.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.360 Vinylidene chloride copolymer coatings for nylon film.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1010 Acrylic and modified acrylic plastics, semirigid and rigid.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1630 Polyethylene phthalate polymers.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3790 Polymer modifiers in semirigid and rigid vinyl chloride plastics.
 
Physical Properties:
Appearance:colorless liquid (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity:0.91600 to 0.91900 @ 25.00 °C.
Pounds per Gallon - (est).: 7.622 to 7.647
Refractive Index:1.40300 to 1.40700 @ 20.00 °C.
Melting Point: -75.00 to -71.00 °C. @ 760.00 mm Hg
Boiling Point: 99.00 to 100.00 °C. @ 760.00 mm Hg
Acid Value: 5.00 max. KOH/g
Vapor Pressure:38.181999 mmHg @ 25.00 °C. (est)
Vapor Density:3.5 ( Air = 1 )
Flash Point: 60.00 °F. TCC ( 15.56 °C. )
logP (o/w): 1.320
Soluble in:
 alcohol
 water, 8717 mg/L @ 25 °C (est)
 water, 1.50E+04 mg/L @ 25 °C (exp)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Type: plastic
Odor Strength:high ,
recommend smelling in a 0.10 % solution or less
Substantivity:4 hour(s) at 100.00 %
plastic acrylate fruity
Odor Description:at 1.00 % in dipropylene glycol. harsh plastic acrylate fruity
Luebke, William tgsc, (1988)
Odor sample from: Berje Inc.
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: not used anymore
plasticisers
 
Suppliers:
Advanced Biotech
ETHYL ACRYLATE 1% IN ETHYL PROPIONATE NATURAL
Odor: Ethereal, rum
Advanced Biotech
ETHYL ACRYLATE 1% IN PG NATURAL
Odor: Ethereal, rum
Arkema
Ethylacrylate
Odor: characteristic
Use: It can be polymerized with each other and copolymerized with other monomers to produce polymers having the optimal properties for your application.
Axxence Aromatic
ETHYL ACRYLATE Natural
Kosher
Sustainability
BASF
Ethyl Acrylate
Covalent Chemical
Ethyl Acrylate
Dow Chemical
Ethyl Acrylate (EA)
EMD Millipore
For experimental / research use only.
Ethyl Acrylate
Excellentia International
Ethyl Acrylate Natural
Lluch Essence
ETHYL ACRYLATE
M&U International
NAT. ETHYL ACRYLATE
Penta International
ETHYL ACRYLATE NATURAL 1% IN ETHYL ALCOHOL
Penta International
ETHYL ACRYLATE NATURAL 1% IN ETHYL PROPIONATE
Penta International
ETHYL ACRYLATE NATURAL 1% IN PROPYLENE GLYCOL
Penta International
ETHYL ACRYLATE NATURAL NEAT
Penta International
ETHYL ACRYLATE
Santa Cruz Biotechnology
For experimental / research use only.
Ethyl Acrylate
Shanghai Vigen Fine Chemical
Ethyl Acrylate
Shiva Chemicals and Pharmaceuticals
Ethyl Acrylate
Sigma-Aldrich
Ethyl acrylate, ≥99.5%, stabilized, FG
Certified Food Grade Products
Silver Fern Chemical
Ethyl Acrylate
Odor: characteristic
Use: Ethyl acrylate is mainly produced for paints, textiles, and non-woven fibers. It is also used as a monomer for acrylic resins and in the production of plastics, rubber, and denture material.
Synerzine
Ethyl Acrylate
SysKem Chemie
Acrylic acid ethylester
TCI AMERICA
For experimental / research use only.
Ethyl Acrylate (stabilized with MEHQ) >99.0%(GC)
WholeChem
Ethyl Acrylate
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 11 - Highly flammable.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
R 43 - May cause sensitisation by skin contact.
S 09 - Keep container in a well-ventilated place.
S 16 - Keep away from sources of ignition - No Smoking.
S 33 - Take precautionary measures against static discharge.
S 36/37 - Wear suitable protective clothing and gloves.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50 800 mg/kg
Bromatologia i Chemia Toksykologiczna. Vol. 12, Pg. 405, 1979.

intraperitoneal-rat LD50 450 mg/kg
Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 36, Pg. 58, 1975.

oral-rabbit LD50 370 mg/kg
GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION
National Technical Information Service. Vol. OTS0521003

oral-mouse LD50 1799 mg/kg
Toxicology Letters. Vol. 11, Pg. 125, 1982.

intraperitoneal-mouse LD50 599 mg/kg
Journal of Dental Research. Vol. 51, Pg. 526, 1972.

oral-cat LD > 800 uL/kg
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS GASTROINTESTINAL: NAUSEA OR VOMITING
National Technical Information Service. Vol. OTS0521003

Dermal Toxicity:
skin-rabbit LD50 500 ul/kg
LIVER: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
National Technical Information Service. Vol. OTS0520180

skin-mouse LD50 2997 mg/kg
National Technical Information Service. Vol. OTS0520999

skin-rat LDLo 1800 mg/kg
Polish Journal of Pharmacology and Pharmacy. Vol. 32, Pg. 223, 1980.

Inhalation Toxicity:
inhalation-rat LC50 1414 ppm/4H
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: DYSPNEA SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
National Technical Information Service. Vol. OTS0520180

inhalation-mouse LC50 16200 mg/m3
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(9), Pg. 55, 1979.

inhalation-guinea pig LCLo 1204 ppm/7H
LUNGS, THORAX, OR RESPIRATION: COUGH BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 317, 1949.

inhalation-human TCLo 50 ppm
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 75, 1969.

inhalation-rabbit TCLo 1204 ppm/7H
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 317, 1949.

 
Safety in Use Information:
Category: food contact acrylic and modified acrylic plastics
IFRA Critical Effect: Sensitization
IFRA: View Standard
Recommendation for ethyl acrylate usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -1.10000
beverages(nonalcoholic): 0.130000.26000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: 0.100000.10000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 0.060001.00000
fruit ices: 0.060001.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -1.10000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on Flavouring Group Evaluation 71: Consideration of aliphatic, linear, alpha,beta-unsaturated carboxylic acids and related esters
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 95 (FGE.95): Consideration of aliphatic, linear or branched-chain saturated and unsaturated alcohols, aldehydes, acids and related esters evaluated by JECFA (69th meeting) structurally related to esters of branched- and straight-chain aliphatic saturated primary alcohols and of one secondary alcohol, and branched- and straight-chain unsaturated carboxylic acids evaluated by EFSA in FGE.05Rev1 (2008)
View page or View pdf

Scientific Opinion on the safety of neutral methacrylate copolymer for the proposed uses as a food additive
View page or View pdf

Scientific Opinion on the safety and efficacy of straight-chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species
View page or View pdf

Scientific Opinion on the safety assessment of the substances (butadiene, ethyl acrylate, methyl methacrylate, styrene) copolymer either not crosslinked or crosslinked with divinylbenzene or 1,3-butanediol dimethacrylate, in nanoform, for use in food contact materials
View page or View pdf

Safety of ethyl acrylate to be used as flavouring
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):140-88-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8821
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WISER:UN 1917
WGK Germany:2
ethyl prop-2-enoate
Chemidplus:0000140885
EPA/NOAA CAMEO:hazardous materials
RTECS:140-88-5
 
References:
 ethyl prop-2-enoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:140-88-5
Pubchem (cid):8821
Pubchem (sid):134975084
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C19238
HMDB (The Human Metabolome Database):HMDB33978
FooDB:FDB012210
Export Tariff Code:2916.12.5010
Haz-Map:View
Household Products:Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Formulations/Preparations:
•water: 0.10% by wt, max; acidity, as acrylic acid: 0.009% by wt, max •typical properties for commercial grade ethyl acrylate available in us are purity 99.0%; acidity (as acrylic acid), 0.0008%; water, 0.03%; inhibitors, 15 or 200 mgkg (ppm) hydroquinone monomethyl ether or 1000 mgkg (ppm) hydroquinone. •99.5% by wt (min) inhibited with 15-20 ppm hydroquinone •99.5% by wt (min) inhibited with hydroquinone or monomethyl ether of hydroquinone •grades: technical (inhibited, usually with hydroquinone or its monomethyl ether); pure uninhibited
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 plasticisers
FRwitch hazel
 
Occurrence (nature, food, other):note
 ananas sativus lindl.
Search Trop Picture
 pineapple fruit
Search Trop Picture
 
Synonyms:
 acrylic acid ethyl ester
 acrylic acid, ethyl ester
 ethoxycarbonyl ethylene
 ethyl 2-propenoate
 ethyl acrylate 1% in ethyl propionate natural
 ethyl acrylate 1% in PG natural
 ethyl acrylate natural
 ethyl acrylic ester
 ethyl ester of acrylic acid
 ethyl prop-2-enoate
 ethyl propenoate
2-propenoic acid ethyl ester
2-propenoic acid, ethyl ester
 
 
Notes:
Flavouring ingredient Although there are some reports claiming that ethyl acrylate is a carcinogen, major respected bodies regard the evidence of human carcinogenicity as weak and/or inconsistent. The International Agency for Research on Cancer stated, "Overall evaluation, Ethyl acrylate is possibly carcinogenic to humans (Group 2B)." The United States Environmental Protection Agency (EPA) states, "Human studies on occupational exposure to ethyl acrylate... have suggested a relationship between exposure to the chemical(s) and colorectal cancer, but the evidence is conflicting and inconclusive. In a study by the National Toxicology Program (NTP), increased incidences of squamous cell papillomas and carcinomas of the forestomach were observed in rats and mice exposed via gavage (experimentally placing the chemical in the stomach). However, the NTP recently determined that these data were not relevant to human carcinogenicity and removed ethyl acrylate from its list of carcinogens." (Occupational exposure generally involves exposure that occurs regularly, over an extended period of time.); Ethyl acrylate is an organic compound primarily used in the preparation of various polymers. It is a clear liquid with an acrid penetrating odor. The human nose is capable of detecting this odor at a thousand times lower concentration then is considered harmful if continuously exposed for some period of time.
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