withania somnifera leaf extract
extract of the leaves of withania somnifera (l.), solanaceae
 
Notes:
None found
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Name: withania somnifera leaf extract
CAS Number: 90147-43-6 
ECHA EC Number: 290-434-9
Category: antimicrobial, antioxidants agents
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antimicrobial agents
antioxidants
bleaching agents
emollients
humectants
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antimicrobial, antioxidants agents
Recommendation for withania somnifera leaf extract usage levels up to:
 not for fragrance use.
 
Recommendation for withania somnifera leaf extract flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
AIDS Citations: Search
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EPA ACToR: Toxicology Data
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National Institute of Allergy and Infectious Diseases: Data
 withania somnifera leaf extract
Chemidplus: 0090147436
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References:
 withania somnifera leaf extract
Pubchem (cas): 90147-43-6
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 ashwagandha leaf
Search Trop  Picture
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Synonyms:
 ajagandha leaf extract
 ashwagandha leaf extract
winter cherry leaf extract
 extract of the leaves of withania somnifera (l.), solanaceae
indian ginseng leaf extract
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Articles:
PubMed: Aqueous Leaf Extract of Withania somnifera as a Potential Neuroprotective Agent in Sleep-deprived Rats: a Mechanistic Study.
PubMed: Withania somnifera Leaf Extract Ameliorates Benzo[a]pyrene-Induced Behavioral and Neuromorphological Alterations by Improving Brain Antioxidant Status in Zebrafish (Danio rerio).
PubMed: Amelioration of Isoproterenol-Induced Oxidative Damage in Rat Myocardium by Withania somnifera Leaf Extract.
PubMed: Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity.
PubMed: Antibacterial activity of Withania somnifera against Gram-positive isolates from pus samples.
PubMed: Hypoglycemic activity of withanolides and elicitated Withania somnifera.
PubMed: Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines.
PubMed: Glioprotective effects of Ashwagandha leaf extract against lead induced toxicity.
PubMed: Differential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidences.
PubMed: Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite.
PubMed: Molecular insight into the immune up-regulatory properties of the leaf extract of Ashwagandha and identification of Th1 immunostimulatory chemical entity.
PubMed: Ashwagandha leaf extract: a potential agent in treating oxidative damage and physiological abnormalities seen in a mouse model of Parkinson's disease.
PubMed: Withanolide induces apoptosis in HL-60 leukemia cells via mitochondria mediated cytochrome c release and caspase activation.
PubMed: Evaluation of the anti-proliferative and anti-oxidative activities of leaf extract from in vivo and in vitro raised Ashwagandha.
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