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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for angelica keiskei extract usage levels up to: | | | not for fragrance use.
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| Recommendation for angelica keiskei extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | archangelica keiskei extract | | | ashitaba extract | | | extract of the whole plant angelica, angelica keiskei, apiaceae |
Articles:
| PubMed:Bioassay-guided isolation and identification of anti-platelet-active compounds from the root of Ashitaba (Angelica keiskei Koidz.). |
| J-Stage:Angelica keiskei Extract Improves Insulin Resistance and Hypertriglyceridemia in Rats Fed a High-Fructose Drink |
| J-Stage:Six New Chalcones from Angelica keiskei Inducing Adiponectin Production in 3T3-L1 Adipocytes |
| J-Stage:Identification of the Plant Origin of Propolis from Jeju Island, Korea, by Observation of Honeybee Behavior and Phytochemical Analysis |
| PubMed:Study on structural and spectral properties of isobavachalcone and 4-hydroxyderricin by computational method. |
| PubMed:Quantitative analysis of phenolic metabolites from different parts of Angelica keiskei by HPLC-ESI MS/MS and their xanthine oxidase inhibition. |
| PubMed:Inhibitory Effects of 4-Hydroxyderricin and Xanthoangelol on Lipopolysaccharide-Induced Inflammatory Responses in RAW264 Macrophages. |
| PubMed:Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. |
| PubMed:[Effect of ashitabe chalcones on the mRNA expression of PI3K and Akt in hepatocytes of rats with diabetes]. |
| PubMed:4-Hydroxyderricin and xanthoangelol from Ashitaba (Angelica keiskei) suppress differentiation of preadiopocytes to adipocytes via AMPK and MAPK pathways. |
| PubMed:[Effects of angelica keiskei chalcone on expression of glucose transporter proteins in liver and skeletal muscle cells of type 2 diabetic rats]. |
| PubMed:Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification. |
| PubMed:Evaluation of acute skin irritation and phototoxicity by aqueous and ethanol fractions of Angelica keiskei. |
| PubMed:Comparison of the toxicity of aqueous and ethanol fractions of Angelica keiskei leaf using the eye irritancy test. |
| PubMed:Isobavachalcone suppresses expression of inducible nitric oxide synthase induced by Toll-like receptor agonists. |
| PubMed:Angelica keiskei ameliorates scopolamine-induced memory impairments in mice. |
| PubMed:Identification of the plant origin of propolis from Jeju Island, Korea, by observation of honeybee behavior and phytochemical analysis. |
| PubMed:The inhibitory effects of representative chalcones contained in Angelica keiskei on melanin biosynthesis in B16 melanoma cells. |
| PubMed:Six new chalcones from Angelica keiskei inducing adiponectin production in 3T3-L1 adipocytes. |
| PubMed:Angelica keiskei extract improves insulin resistance and hypertriglyceridemia in rats fed a high-fructose drink. |
| PubMed:Component analysis of propolis collected on Jeju Island, Korea. |
| PubMed:Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice. |
| PubMed:Application of mixture analysis to crude materials from natural resources (III): NMR spectral studies to analyze chalcones from Angelica keiskei. |
| PubMed:The effects of Angelica keiskei Koidz on the expression of antioxidant enzymes related to lipid profiles in rats fed a high fat diet. |
| PubMed:Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei. |
| PubMed:Xanthoangelols isolated from Angelica keiskei inhibit inflammatory-induced plasminogen activator inhibitor 1 (PAI-1) production. |
| PubMed:Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition. |
| PubMed:Chalcones isolated from Angelica keiskei and their inhibition of IL-6 production in TNF-α-stimulated MG-63 cell. |
| PubMed:A deuterium-labelling mass spectrometry-tandem diode-array detector screening method for rapid discovery of naturally occurring electrophiles. |
| PubMed:An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract. |
| PubMed:4-Hydroxyderricin from Angelica keiskei roots induces caspase-dependent apoptotic cell death in HL60 human leukemia cells. |
| PubMed:Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation. |
| PubMed:Anti-Inflammatory activity of Angelica keiskei through suppression of mitogen-activated protein kinases and nuclear factor-kappaB activation pathways. |
| PubMed:C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity. |
| PubMed:Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma. |
| PubMed:Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation. |
| PubMed:Selinidin suppresses IgE-mediated mast cell activation by inhibiting multiple steps of Fc epsilonRI signaling. |
| PubMed:Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. |
| PubMed:Effects of dietary Angelica keiskei on serum and liver lipid profiles, and body fat accumulations in rats. |
| PubMed:Antidiabetic activities of chalcones isolated from a Japanese Herb, Angelica keiskei. |
| PubMed:Beneficial effect of xanthoangelol, a chalcone compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. |
| PubMed:[Toxicological analysis of a case of Datura stramonium poisoning]. |
| PubMed:Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. |
| PubMed:Beneficial effect of laserpitin, a coumarin compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats. |
| PubMed:Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. |
| PubMed:Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. |
| PubMed:Xanthoangelol D isolated from the roots of Angelica keiskei inhibits endothelin-1 production through the suppression of nuclear factor-kappaB. |
| PubMed:New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants. |
| PubMed:Hypotensive and lipid regulatory actions of 4-hydroxyderricin, a chalcone from Angelica keiskei, in stroke-prone spontaneously hypertensive rats. |
| PubMed:Green vegetable drink consumption protects peripheral lymphocytes DNA damage in Korean smokers. |
| PubMed:Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots. |
| PubMed:Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. |
| PubMed:Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol. |
| PubMed:Effects of dietary Angelica keiskei on lipid metabolism in stroke-prone spontaneously hypertensive rats. |
| PubMed:Optimal conditions for identifying 80Br and 128I in health food Angelica keiskei using rapid epithermal neutron activation analysis. |
| PubMed:Effects of extract from Angelica keiskei and its component, cynaroside, on the hepatic bromobenzene-metabolizing enzyme system in rats. |
| PubMed:Artery relaxation by chalcones isolated from the roots of Angelica keiskei. |
| PubMed:Effects of angiotensin I-converting enzyme inhibitor from Ashitaba (Angelica keiskei) on blood pressure of spontaneously hypertensive rats. |
| PubMed:The effects of xanthoangelol E on arachidonic acid metabolism in the gastric antral mucosa and platelet of the rabbit. |
| PubMed:Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. |
| PubMed:Anti-tumor-promotion by principles obtained from Angelica keiskei. |
| PubMed:Inhibition of gastric H+, K(+)-ATPase by chalcone derivatives, xanthoangelol and 4-hydroxyderricin, from Angelica keiskei Koidzumi. |
| PubMed:[Chemical components of the roots of Angelica keiskei Koidzumi. III. The structure of a new dihydrofurocoumarin (author's transl)]. |
| PubMed:[Chemical components of the roots of Angelica keiskei Koidzumi. II. The structure of the chalcone derivatives (author's transl)]. |
| PubMed:[Pharmacognostical studies on umbelliferous plants. XVIII. On the constituents of the roots of Angelica Keiskei Koidzumi]. |
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