angelica keiskei extract
extract of the whole plant angelica, angelica keiskei, apiaceae
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Category: cosmetic agents
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
skin conditioning
skin protecting agents
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 None found
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic agents
Recommendation for angelica keiskei extract usage levels up to:
 not for fragrance use.
Recommendation for angelica keiskei extract flavor usage levels up to:
 not for flavor use.
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Safety References:
None found
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None found
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
None Found
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Potential Uses:
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Occurrence (nature, food, other): note
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 archangelica keiskei extract
 ashitaba extract
 extract of the whole plant angelica, angelica keiskei, apiaceae
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PubMed: Bioassay-guided isolation and identification of anti-platelet-active compounds from the root of Ashitaba (Angelica keiskei Koidz.).
J-Stage: Angelica keiskei Extract Improves Insulin Resistance and Hypertriglyceridemia in Rats Fed a High-Fructose Drink
J-Stage: Six New Chalcones from Angelica keiskei Inducing Adiponectin Production in 3T3-L1 Adipocytes
J-Stage: Identification of the Plant Origin of Propolis from Jeju Island, Korea, by Observation of Honeybee Behavior and Phytochemical Analysis
PubMed: Study on structural and spectral properties of isobavachalcone and 4-hydroxyderricin by computational method.
PubMed: Quantitative analysis of phenolic metabolites from different parts of Angelica keiskei by HPLC-ESI MS/MS and their xanthine oxidase inhibition.
PubMed: Inhibitory Effects of 4-Hydroxyderricin and Xanthoangelol on Lipopolysaccharide-Induced Inflammatory Responses in RAW264 Macrophages.
PubMed: Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K.
PubMed: [Effect of ashitabe chalcones on the mRNA expression of PI3K and Akt in hepatocytes of rats with diabetes].
PubMed: 4-Hydroxyderricin and xanthoangelol from Ashitaba (Angelica keiskei) suppress differentiation of preadiopocytes to adipocytes via AMPK and MAPK pathways.
PubMed: [Effects of angelica keiskei chalcone on expression of glucose transporter proteins in liver and skeletal muscle cells of type 2 diabetic rats].
PubMed: Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification.
PubMed: Evaluation of acute skin irritation and phototoxicity by aqueous and ethanol fractions of Angelica keiskei.
PubMed: Comparison of the toxicity of aqueous and ethanol fractions of Angelica keiskei leaf using the eye irritancy test.
PubMed: Isobavachalcone suppresses expression of inducible nitric oxide synthase induced by Toll-like receptor agonists.
PubMed: Angelica keiskei ameliorates scopolamine-induced memory impairments in mice.
PubMed: Identification of the plant origin of propolis from Jeju Island, Korea, by observation of honeybee behavior and phytochemical analysis.
PubMed: The inhibitory effects of representative chalcones contained in Angelica keiskei on melanin biosynthesis in B16 melanoma cells.
PubMed: Six new chalcones from Angelica keiskei inducing adiponectin production in 3T3-L1 adipocytes.
PubMed: Angelica keiskei extract improves insulin resistance and hypertriglyceridemia in rats fed a high-fructose drink.
PubMed: Component analysis of propolis collected on Jeju Island, Korea.
PubMed: Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice.
PubMed: Application of mixture analysis to crude materials from natural resources (III): NMR spectral studies to analyze chalcones from Angelica keiskei.
PubMed: The effects of Angelica keiskei Koidz on the expression of antioxidant enzymes related to lipid profiles in rats fed a high fat diet.
PubMed: Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei.
PubMed: Xanthoangelols isolated from Angelica keiskei inhibit inflammatory-induced plasminogen activator inhibitor 1 (PAI-1) production.
PubMed: Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition.
PubMed: Chalcones isolated from Angelica keiskei and their inhibition of IL-6 production in TNF-α-stimulated MG-63 cell.
PubMed: A deuterium-labelling mass spectrometry-tandem diode-array detector screening method for rapid discovery of naturally occurring electrophiles.
PubMed: An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract.
PubMed: 4-Hydroxyderricin from Angelica keiskei roots induces caspase-dependent apoptotic cell death in HL60 human leukemia cells.
PubMed: Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation.
PubMed: Anti-Inflammatory activity of Angelica keiskei through suppression of mitogen-activated protein kinases and nuclear factor-kappaB activation pathways.
PubMed: C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity.
PubMed: Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma.
PubMed: Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.
PubMed: Selinidin suppresses IgE-mediated mast cell activation by inhibiting multiple steps of Fc epsilonRI signaling.
PubMed: Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma.
PubMed: Effects of dietary Angelica keiskei on serum and liver lipid profiles, and body fat accumulations in rats.
PubMed: Antidiabetic activities of chalcones isolated from a Japanese Herb, Angelica keiskei.
PubMed: Beneficial effect of xanthoangelol, a chalcone compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats.
PubMed: [Toxicological analysis of a case of Datura stramonium poisoning].
PubMed: Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells.
PubMed: Beneficial effect of laserpitin, a coumarin compound from Angelica keiskei, on lipid metabolism in stroke-prone spontaneously hypertensive rats.
PubMed: Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects.
PubMed: Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells.
PubMed: Xanthoangelol D isolated from the roots of Angelica keiskei inhibits endothelin-1 production through the suppression of nuclear factor-kappaB.
PubMed: New anticancer agents: in vitro and in vivo evaluation of the antitumor and antimetastatic actions of various compounds isolated from medicinal plants.
PubMed: Hypotensive and lipid regulatory actions of 4-hydroxyderricin, a chalcone from Angelica keiskei, in stroke-prone spontaneously hypertensive rats.
PubMed: Green vegetable drink consumption protects peripheral lymphocytes DNA damage in Korean smokers.
PubMed: Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots.
PubMed: Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects.
PubMed: Antitumor and antimetastatic activities of Angelica keiskei roots, part 1: Isolation of an active substance, xanthoangelol.
PubMed: Effects of dietary Angelica keiskei on lipid metabolism in stroke-prone spontaneously hypertensive rats.
PubMed: Optimal conditions for identifying 80Br and 128I in health food Angelica keiskei using rapid epithermal neutron activation analysis.
PubMed: Effects of extract from Angelica keiskei and its component, cynaroside, on the hepatic bromobenzene-metabolizing enzyme system in rats.
PubMed: Artery relaxation by chalcones isolated from the roots of Angelica keiskei.
PubMed: Effects of angiotensin I-converting enzyme inhibitor from Ashitaba (Angelica keiskei) on blood pressure of spontaneously hypertensive rats.
PubMed: The effects of xanthoangelol E on arachidonic acid metabolism in the gastric antral mucosa and platelet of the rabbit.
PubMed: Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI.
PubMed: Anti-tumor-promotion by principles obtained from Angelica keiskei.
PubMed: Inhibition of gastric H+, K(+)-ATPase by chalcone derivatives, xanthoangelol and 4-hydroxyderricin, from Angelica keiskei Koidzumi.
PubMed: [Chemical components of the roots of Angelica keiskei Koidzumi. III. The structure of a new dihydrofurocoumarin (author's transl)].
PubMed: [Chemical components of the roots of Angelica keiskei Koidzumi. II. The structure of the chalcone derivatives (author's transl)].
PubMed: [Pharmacognostical studies on umbelliferous plants. XVIII. On the constituents of the roots of Angelica Keiskei Koidzumi].
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