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urtica dioica extract
extract of the aerial parts of the nettle, urtica dioica l., urticaceae

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CAS Number: 84012-40-8
ECHA EC Number:281-685-5
Category:cosmetic agents, dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antidandruff agents
astringents
hair conditioning
skin conditioning
soothing agents
tonic
 
Suppliers:
AuNutra® Industries
Nettle P.E.
Axsyn
For experimental / research use only.
Urtica dioica, ext.
Carrubba
nettle extract
Changsha Organic Herb
Nettle Extract
Grau Aromatics
NETTLE WORT EXTRACT HS 2455 G
(hydrosoluble)
Grau Aromatics
NETTLE WORT EXTRACT LS 4037 G
(liposoluble)
H. Erhard Wagner
PhytoVital Stinging Nettle
Naturex
Nettle Extract
NAT healthy™
Rung International
Stinging Nettle Extract
Odor: characteristic
Use: Stinging Nettle is a major commercial source of chlorophyll which is commonly used as a coloring agent . The stinging nettle (Urtica dioica) is used in foods such as nettle soup and nettle cheese. Stinging nettle leaves are rich in chlorophyll a and b, xanthophylls, β-carotene and vitamins A, B2 and C.
SRS Aromatics
NETTLE WORT EXTRACT HS 2455 G
SRS Aromatics
NETTLE WORT EXTRACT LS 4037 G
Symrise
Extrapone® Stinging Nettle
Life Essentials - Botanicals
Odor: characteristic
Use: Extrapone® Stinging Nettle contains the extract of dried stinging nettle leaves prepared in propylene glycol, water and preservatives. Stinging nettles (Urtica Dioica L.) used for our Extrapone® are mainly collected in Eastern Europe. The stinging nettle leaves are harvested, cleaned and if necessary comminuted, aqueously extracted (maceration/percolation) and filtrated. The filtrate is concentrated by distillation, prepared in a mixture of propylene glycol, water and preservative and clear filtrated after an individual ripening time. 1 kg Extrapone® Stinging Nettle contains the aqueous soluble ingredients of approx. 0.2 kg dried respectively of approx. 1.1 kg fresh stinging nettle leaves. Dried plant material - extract (Extrapone® Stinging Nettle) - ratio: 0.2 : 1. Fresh plant material - extract (Extrapone® Stinging Nettle) - ratio: 1.1 : 1
Vege Tech
nettle extract
Vege Tech
Organic Nettle Extract
Xi'an Greena Biotech
Nettle Extract
Odor: characteristic
Use: Nettle is a plant in the Urticaceae family that is more commonly known as urtica dioica, or stinging nettle.Nettle is a perennial flowering plant that has been used medicinally for ages, dating back as far as Ancient Greece.Today, nettle can be found all over the world, but its origins are in the colder regions of Europe and Asia.While best known for the stinging reaction that occurs when the skin comes into contact with the fine hairs located on its leaves and stems.Traditionally used as a nutritive and “blood cleanser” or alterative agent, a substantial pharmacological and clinical literature supports its use for arthritic and allergic symptoms and improving urological symptoms of benign prostatic hyperplasia.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic agents, dietary supplements
Recommendation for urtica dioica extract usage levels up to:
 not for fragrance use.
 
Recommendation for urtica dioica extract flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Outcome of the consultation with Member States and EFSA on the basic substance applications for Urtica spp. for use in plant protection as insecticide, acaricide and fungicide
View page or View pdf

ClinicalTrials.gov:search
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
urtica dioica l. extract
Chemidplus:0084012408
 
References:
 urtica dioica l. extract
Pubchem (sid):3774175
 
Other Information:
Export Tariff Code:1302.19.0000
Household Products:Search
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antidandruff agents
 astringents
 hair conditioning
 skin conditioning
 soothing agents
FLtonic
 
Occurrence (nature, food, other):note
 nettle stinging nettle
Search Trop Picture
 
Synonyms:
 bichu booti extract
 extract of the aerial parts of the nettle, urtica dioica l., urticaceae
extrapone stinging nettle (Symrise)
greater nettle extract
stinging nettle extract
 nettle P.E.
 nettle wort extract HS 2455 G (Grau)
 nettle wort extract LS 4037 G (Grau)
 phytovital stinging nettle
 urtica dioica, ext.
 urtica galeopsifolia extract
 yi zhu qian ma extract
 

Articles:

PubMed:Urtica dioica leaves modulates muscarinic cholinergic system in the hippocampus of streptozotocin-induced diabetic mice.
PubMed:Antimicrobial activity of methanolic extracts of sambucus ebulus and urtica dioica against clinical isolates of methicillin resistant Staphylococcus aureus.
PubMed:Protective effect of Urtica dioica methanol extract against experimentally induced urinary calculi in rats.
PubMed:Evaluation of alpha- amylase inhibition by Urtica dioica and Juglans regia extracts.
PubMed:Protective effect of Urtica dioica L against nicotine-induced damage on sperm parameters, testosterone and testis tissue in mice.
PubMed:Effects of urtica dioica extract on experimental acute pancreatitis model in rats.
PubMed:The development and in vitro evaluation of herbal pellets coated with Eudragit FS 30.
PubMed:Effect of Urtica dioica Leaf Alcoholic and Aqueous Extracts on the Number and the Diameter of the Islets in Diabetic Rats.
PubMed:Medicinal plant extracts can variously modify biofilm formation in Escherichia coli.
PubMed:Urtica dioica extract attenuates depressive like behavior and associative memory dysfunction in dexamethasone induced diabetic mice.
PubMed:Improved glycemic control in patients with advanced type 2 diabetes mellitus taking Urtica dioica leaf extract: a randomized double-blind placebo-controlled clinical trial.
PubMed:Antioxidant and apoptotic effects of an aqueous extract of Urtica dioica on the MCF-7 human breast cancer cell line.
PubMed:[Study of antioxidant activity of phenolic compounds from some species of Georgian flora].
PubMed:Quantitative determination of plant phenolics in Urtica dioica extracts by high-performance liquid chromatography coupled with tandem mass spectrometric detection.
PubMed:Effect of Urtica dioica on memory dysfunction and hypoalgesia in an experimental model of diabetic neuropathy.
PubMed:Effects of bioactive-rich extracts of pomegranate, persimmon, nettle, dill, kale and Sideritis and isolated bioactives on arachidonic acid induced markers of platelet activation and aggregation.
PubMed:Bioactive-rich extracts of persimmon, but not nettle, Sideritis, dill or kale, increase eNOS activation and NO bioavailability and decrease endothelin-1 secretion by human vascular endothelial cells.
PubMed:Anti-mycobacterial screening of five Indian medicinal plants and partial purification of active extracts of Cassia sophera and Urtica dioica.
PubMed:Antinociceptive and anti-inflammatory effects of Urtica dioica leaf extract in animal models.
PubMed:[In Vitro Effect of Ankaferd Blood Stopper®, a Plant Extract Against Mycobacterium tuberculosis Isolates].
PubMed:Screening antimicrobial activity of various extracts of Urtica dioica.
PubMed:Antidiabetic effect of hydroalcholic urticadioica leaf extract in male rats with fructose-induced insulin resistance.
PubMed:Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders.
PubMed:High-antibacterial activity of Urtica spp. seed extracts on food and plant pathogenic bacteria.
PubMed:Therapeutic potential of some plant extracts used in Turkish traditional medicine on streptozocin-induced type 1 diabetes mellitus in rats.
PubMed:Pharmacological and toxicological evaluation of Urtica dioica.
PubMed:Sphaeranthus indicus induces apoptosis through mitochondrial-dependent pathway in HL-60 cells and exerts cytotoxic potential on several human cancer cell lines.
PubMed:An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts.
PubMed:Water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants.
PubMed:The effect of hydro alcoholic nettle (Urtica dioica) extract on oxidative stress in patients with type 2 diabetes: a randomized double-blind clinical trial.
PubMed:Effect of Urtica dioica L. (Urticaceae) on testicular tissue in STZ-induced diabetic rats.
PubMed:Safety and efficacy of Setarud (IMOD TM ) among people living with HIV/AIDS: a review.
PubMed:The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
PubMed:Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
PubMed:Ameliorative influence of Urtica dioica L against cisplatin-induced toxicity in mice bearing Ehrlich ascites carcinoma.
PubMed:Protective Effect of Urtica dioica L. (Urticaceae) on Morphometric and Morphologic Alterations of Seminiferous Tubules in STZ Diabetic Rats.
PubMed:Elemental and structural analysis of silicon forms in herbal drugs using silicon-29 MAS NMR and WD-XRF spectroscopic methods.
PubMed:[Gastroprotective action of the nettle extract in experimental peptic ulcer].
PubMed:Protective role of Urtica dioica L. (Urticaceae) extract on hepatocytes morphometric changes in STZ diabetic Wistar rats.
PubMed:Phenolic composition and antioxidant properties of some traditionally used medicinal plants affected by the extraction time and hydrolysis.
PubMed:Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper.
PubMed:Effects of water extract of Urtica dioica L. and modified atmosphere packaging on the shelf life of ground beef.
PubMed:[The effect of dry standardized plant extracts on the process of arbutin release from topical preparations produced on Carbopol base].
PubMed:Antidiabetic effect of some medicinal plants of Oriental Morocco in neonatal non-insulin-dependent diabetes mellitus rats.
PubMed:Insulin mimetics in Urtica dioica: structural and computational analyses of Urtica dioica extracts.
PubMed:The efficacy of Ankaferd Blood Stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model.
PubMed:The effects of Urtica dioica L. leaf extract on aniline 4-hydroxylase in mice.
PubMed:Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. Schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christi L.) extracts on plants pathogenic fungi.
PubMed:The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats.
PubMed:Effects of Urtica dioica extract on lipid profile in hypercholesterolemic rats.
PubMed:Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis.
PubMed:In vivo hemostatic effect of the medicinal plant extract Ankaferd Blood Stopper in rats pretreated with warfarin.
PubMed:Effect of Urtica dioica on morphometric indices of kidney in streptozotocin diabetic rats--a stereological study.
PubMed:Effects of Urtica dioica L. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats.
PubMed:Maintaining a physiological blood glucose level with 'glucolevel', a combination of four anti-diabetes plants used in the traditional arab herbal medicine.
PubMed:Antimicrobial activity of plant extract Ankaferd Blood Stopper.
PubMed:The granule cell density of the dentate gyrus following administration of Urtica dioica extract to young diabetic rats.
PubMed:Combined HPLC-CUPRAC (cupric ion reducing antioxidant capacity) assay of parsley, celery leaves, and nettle.
PubMed:Toxicological assessment of P-9801091 plant mixture extract after chronic administration in CBA/HZg mice--a biochemical and histological study.
PubMed:Haemostatic actions of the folkloric medicinal plant extract Ankaferd Blood Stopper.
PubMed:Biological screening of some Turkish medicinal plant extracts for antimicrobial and toxicity activities.
PubMed:In vitro nematicidal effects of medicinal plants from the Sierra de Huautla, Biosphere Reserve, Morelos, Mexico against Haemonchus contortus infective larvae.
PubMed:Efficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trial.
PubMed:A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: urticae radix.
PubMed:The protective activity of Urtica dioica leaves on blood glucose concentration and beta-cells in streptozotocin-diabetic rats.
PubMed:Antihypercholesterolaemic and antioxidant activity assessment of some plants used as remedy in Turkish folk medicine.
PubMed:[Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial].
PubMed:Inhibition of rat platelet aggregation by Urtica dioica leaves extracts.
PubMed:Effect of Urtica dioica extract intake upon blood lipid profile in the rats.
PubMed:Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract.
PubMed:Long-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trial.
PubMed:The role of urtica dioica (urticaceae) in the prevention of oxidative stress caused by tourniquet application in rats.
PubMed:Inhibition of the protease activity of the light chain of type A botulinum neurotoxin by aqueous extract from stinging nettle (Urtica dioica) leaf.
PubMed:Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected species.
PubMed:Ameliorative effect of IDS 30, a stinging nettle leaf extract, on chronic colitis.
PubMed:Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer.
PubMed:Antioxidant properties of some medicinal plants: Prangos ferulacea (Apiaceae), Sedum sempervivoides (Crassulaceae), Malva neglecta (Malvaceae), Cruciata taurica (Rubiaceae), Rosa pimpinellifolia (Rosaceae), Galium verum subsp. verum (Rubiaceae), Urtica dioica (Urticaceae).
PubMed:[Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). Results of a randomized, double-blind, placebo controlled multicenter study after 12 months].
PubMed:Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.).
PubMed:Antihyperglycemic activity of the aqueous extract of Urtica dioica.
PubMed:Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats.
PubMed:The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats.
PubMed:Some medicinal plants as immunostimulant for fish.
PubMed:Modulatory effect of Urtica dioica L. (Urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice.
PubMed:Long-term efficacy and safety of PRO 160/120 (a combination of sabal and urtica extract) in patients with lower urinary tract symptoms (LUTS).
PubMed:Glutathione S-transferases and malondialdehyde in the liver of NOD mice on short-term treatment with plant mixture extract P-9801091.
PubMed:In vitro immunomodulatory activity of flavonoid glycosides from Urtica dioica L.
PubMed:Cardiovascular effects of Urtica dioica L. in isolated rat heart and aorta.
PubMed:In vitro antioxidant activity of non-cultivated vegetables of ethnic Albanians in southern Italy.
PubMed:[General practice study with nettle extract. Arthrosis patient need fewer non-steroidal anti-inflammatory drugs].
PubMed:Effects of the antirheumatic remedy hox alpha--a new stinging nettle leaf extract--on matrix metalloproteinases in human chondrocytes in vitro.
PubMed:Immunosuppressant effect of IDS 30, a stinging nettle leaf extract, on myeloid dendritic cells in vitro.
PubMed:Effect of 'antidiabetis' herbal preparation on serum glucose and fructosamine in NOD mice.
PubMed:Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat.
PubMed:Combined sabal and urtica extract compared with finasteride in men with benign prostatic hyperplasia: analysis of prostate volume and therapeutic outcome.
PubMed:Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract.
PubMed:Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB.
PubMed:The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse.
PubMed:[Drug therapy of benign prostatic hyperplasia].
PubMed:Inhibition of 5 α-reductase and aromatase by PHL-00801 (Prostatonin®), a combination of PY102 (Pygeum africanum) and UR102 (Urtica dioica) extracts.
PubMed:[Cytokine secretion in whole blood of healthy subjects following oral administration of Urtica dioica L. plant extract].
PubMed:Ex-vivo in-vitro inhibition of lipopolysaccharide stimulated tumor necrosis factor-alpha and interleukin-1 beta secretion in human whole blood by extractum urticae dioicae foliorum.
PubMed:[Anti-inflammatory effect of Urtica dioica folia extract in comparison to caffeic malic acid].
PubMed:The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes.
PubMed:Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots.
PubMed:Effects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasia.
PubMed:Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses.
PubMed:Inhibition of adrenaline-induced aggregation of human platelets by Pakistani medicinal plants.
PubMed:[Biologically active compounds from the aqueous extract of Urtica dioica].
 
Notes:
Astringent, toner for hair care and growth, contains tannins.
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