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acetaldehyde ethyl isopropyl acetal
1-ethoxy-1-isopropoxyethane

Supplier Sponsors

CAS Number: 25334-93-4Picture of molecule3D/inchi
FDA UNII: P6I82WL83F
Nikkaji Web:J422.161C
XlogP3-AA:1.60 (est)
Molecular Weight:132.20292000
Formula:C7 H16 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments:
Racemate. 90 % Acetaldehyde ethyl isopropyl acetal, 8% Acetaldehyde diethylacetal and less than 0.5 % of each: isopropyl vinyl ether, ethyl acetate, isopropyl acetate and acetaldehyde (Flavour Industry, 2011 c).
Category:flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI:Search
DG SANTE Food Flavourings:06.137 acetaldehyde ethyl isopropyl acetal
FEMA Number:4432 (+/-)-acetaldehyde ethyl isopropyl acetal
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):25334-93-4 ; (+/-)-ACETALDEHYDE ETHYL ISOPROPYL ACETAL
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 90.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.84000 @ 25.00 °C.
Refractive Index:1.39600 @ 20.00 °C.
Boiling Point: 126.00 °C. @ 760.00 mm Hg
Vapor Pressure:14.827000 mmHg @ 25.00 °C. (est)
Flash Point: 58.00 °F. TCC ( 14.60 °C. ) (est)
logP (o/w): 1.375 (est)
Soluble in:
 alcohol
 water, 3708 mg/L @ 25 °C (est)
Insoluble in:
 water
Similar Items:note
acetaldehyde ethyl propyl acetal
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Aston Chemical
For experimental / research use only.
2-(1-ethoxyethoxy)propane
Parchem
acetaldehyde ethyl isopropyl acetal
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 12.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 9500 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 20.0000030.00000
beverages(alcoholic): 20.0000030.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: 20.0000030.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: 20.0000030.00000
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): --
Fats and oils, and fat emulsions (type water-in-oil) (02.0): --
Edible ices, including sherbet and sorbet (03.0): 20.0000030.00000
Processed fruit (04.1): --
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): --
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): --
Meat and meat products, including poultry and game (08.0): --
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): --
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): --
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 20.0000030.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 20.0000030.00000
Ready-to-eat savouries (15.0): --
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
 
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on Flavouring Group Evaluation 3, Revision 2 (FGE.03Rev2): Acetals of branched- and straight-chain aliphatic saturated primary alcohols and branched- and straight-chain saturated or unsaturated aldehydes, an ester of a hemiacetal and an orthoester of formic acid, from chemical groups 1, 2 and 4
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):25334-93-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :91409
National Institute of Allergy and Infectious Diseases:Data
2-(1-ethoxyethoxy)propane
Chemidplus:0025334934
 
References:
 2-(1-ethoxyethoxy)propane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:25334-93-4
Pubchem (cid):91409
Pubchem (sid):135047736
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
ChemSpider:View
 
Potential Blenders and core components note
For Odor
animal
para-
cresyl phenyl acetate
FL/FR
balsamic
propyl cinnamate
FL/FR
tetrahydrofurfuryl cinnamate
FL/FR
citrus
petitgrain combava oil
FR
fatty
(E)-2-
octenal
FL/FR
floral
allyl anthranilate
FL/FR
anisyl propanal / methyl anthranilate schiff's base
FR
benzaldehyde propylene glycol acetal
FL/FR
dimethyl benzyl carbinol
FL/FR
2,4-
dimethyl cyclohexyl methyl acetate
FR
lilac pentanol
FL/FR
magnolia indene
FR
narcissus acetate
FL/FR
ocean propanal / methyl anthranilate schiff's base
FR
phenyl acetaldehyde diisobutyl acetal
FL/FR
iso
propyl phenyl acetate
FL/FR
reseda acetal
FR
laevo-
rose oxide
FL/FR
tea acetate
FR
fruity
(E)-2-
hexen-1-ol
FL/FR
2-
hexen-1-ol
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR
2-iso
butyl thiazole
FL/FR
cumin acetaldehyde
FL/FR
3,5,6-neo
cyclocitral
FR
diphenyl oxide
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
heptyl cinnamate
FL/FR
(Z)-2-
hexen-1-ol
FL/FR
3-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl benzoate
FL/FR
(Z)-3-
hexen-1-yl lactate
FL/FR
(Z)-3-
hexen-1-yl methyl carbonate
FL/FR
3-
hexenal
FL/FR
hexoxyacetaldehyde dimethyl acetal
FR
hexyl heptanoate
FL/FR
ivy carbaldehyde
FL/FR
2,4-
ivy carbaldehyde
FL/FR
3,6-
ivy carbaldehyde
FL/FR
3,5-
ivy carbaldehyde
FL/FR
ivy dioxolane
FR
(Z)-
leaf acetal
FL/FR
leafy acetal
FL/FR
leafy oxime
FR
methyl heptine carbonate
FL/FR
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR
(Z)-5-
octen-1-yl propionate
FL/FR
phenethyl acetal
FR
phenoxyacetaldehyde 50% in benzyl alcohol
FR
3-
phenyl propionaldehyde
FL/FR
iso
propyl phenyl propionaldehyde
FR
iso
propyl quinoline
FR
rose leaf absolute (rosa centifolia)
FL/FR
styralyl acetate
FL/FR
herbal
sweet
basil absolute
FL/FR
herbal heptane
FR
minty
iso
pulegyl formate
FL/FR
pine
plectranthus glandulosus hook f. leaf oil cameroon
FR
waxy
allyl nonanoate
FL/FR
For Flavor
No flavor group found for these
acetaldehyde di-(Z)-3-hexen-1-yl acetal
FL/FR
allyl anthranilate
FL/FR
heptyl cinnamate
FL/FR
3-
hexen-1-ol
FL/FR
(E)-2-
hexenal
FL
2-
hexenal
FL
hexyl heptanoate
FL/FR
3,5-
ivy carbaldehyde
FL/FR
ivy carbaldehyde
FL/FR
3-
methyl-3-pentanol
FL
iso
pulegyl formate
FL/FR
tetrahydrofurfuryl cinnamate
FL/FR
aromatic
aromatic
leafy acetal
FL/FR
fatty
(Z)-3-
hexen-1-yl benzoate
FL/FR
(E)-2-
octenal
FL/FR
floral
laevo-
rose oxide
FL/FR
fruity
benzaldehyde propylene glycol acetal
FL/FR
2-
hexen-1-ol
FL/FR
lilac pentanol
FL/FR
propyl cinnamate
FL/FR
styralyl acetate
FL/FR
green
acetaldehyde butyl phenethyl acetal
FL/FR
acetaldehyde ethyl phenethyl acetal
FL/FR
2-iso
butyl thiazole
FL/FR
cumin acetaldehyde
FL/FR
diphenyl oxide
FL/FR
galbanum oil terpeneless
FL/FR
galbanum oleoresin
FL/FR
geranium absolute
FL/FR
(Z)-2-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-ol
FL/FR
(E)-2-
hexen-1-yl acetate
FL/FR
(Z)-3-
hexen-1-yl lactate
FL/FR
(Z)-3-
hexen-1-yl methyl carbonate
FL/FR
3-
hexenal
FL/FR
2,4-
ivy carbaldehyde
FL/FR
3,6-
ivy carbaldehyde
FL/FR
(Z)-
leaf acetal
FL/FR
methyl heptine carbonate
FL/FR
narcissus acetate
FL/FR
(E,Z)-2,6-
nonadien-1-yl acetate
FL/FR
octanal dimethyl acetal
FL/FR
(Z)-5-
octen-1-yl propionate
FL/FR
phenyl acetaldehyde diisobutyl acetal
FL/FR
3-
phenyl propionaldehyde
FL/FR
rose leaf absolute (rosa centifolia)
FL/FR
herbal
sweet
basil absolute
FL/FR
honey
iso
propyl phenyl acetate
FL/FR
medicinal
dimethyl benzyl carbinol
FL/FR
phenolic
para-
cresyl phenyl acetate
FL/FR
waxy
allyl nonanoate
FL/FR
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(+/-)-acetaldehyde ethyl isopropyl acetal
(±)-acetaldehyde ethyl isopropyl acetal
1-ethoxy-1-(2-propoxy) ethane
1-ethoxy-1-(2-propoxy)ethane
1-ethoxy-1-isopropoxyethane
2-(1-ethoxyethoxy) propane
2-(1-ethoxyethoxy)propane
 propane, 2-(1-ethoxyethoxy)-
 propane,2-(1-ethoxyethoxy)-
 
 
Notes:
None found
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