EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

oxidised glutathione
L-gamma- glutamyl-L-cysteinyl-, (2,2')-disulfide

Supplier Sponsors

CAS Number: 27025-41-8Picture of molecule3D/inchi
Other(deleted CASRN):10421-65-5
ECHA EINECS - REACH Pre-Reg:248-170-7
FDA UNII: ULW86O013H
Nikkaji Web:J415.688I
Beilstein Number:1718700
MDL:MFCD00063106
XlogP3-AA:-9.10 (est)
Molecular Weight:612.63744000
Formula:C20 H32 N6 O12 S2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:emollients, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 3.002e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
skin conditioning - emollient
 
Suppliers:
BOC Sciences
For experimental / research use only.
Glutathione Impurity C >98%
Odor: characteristic
Use: NOV-002 is a stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin (1000:1) with potential chemoprotective and immunomodulating activities.
EMD Millipore
For experimental / research use only.
Glutathione, Oxidized, Free Acid
Glentham Life Sciences
L-Glutathione oxidised, 98%
Jiangyin Healthway
Oxidized Glutathione
New functional food ingredients
Meafo
For experimental / research use only.
L-Glutathione oxidized 98%
Santa Cruz Biotechnology
For experimental / research use only.
Glutathione, oxidized ≥95%
Sigma-Aldrich: Sigma
For experimental / research use only.
L-Glutathione oxidized ≥98% (HPLC)
TCI AMERICA
For experimental / research use only.
Glutathione oxidized form >98.0%(HPLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 > 2000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

oral-mouse LD50 > 5000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

intravenous-rat LD50 > 2000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

oral-rat LD50 > 5000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

Dermal Toxicity:
subcutaneous-mouse LD50 > 2000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

subcutaneous-rat LD50 > 2000 mg/kg
Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
emollients, skin conditioning
Recommendation for oxidised glutathione usage levels up to:
 not for fragrance use.
 
Recommendation for oxidised glutathione flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :65359
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
Chemidplus:0027025418
RTECS:MC0556500 for cas# 27025-41-8
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):65359
Pubchem (sid):135022908
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C00127
HMDB (The Human Metabolome Database):HMDB03337
FooDB:FDB023147
Export Tariff Code:2937.19.0000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 bi(glutathion-S-yl)
N,N'-(dithiobis(1-((carboxymethyl)carbamoyl)ethylene))di-, L-
L-gamma- glutamyl-L-cysteinyl-, (2,2')-disulfide
L-oxidized glutathione
 glutathione disulfide
 oxiglutationa
 oxigluthione
 
 
Notes:
Glutathione disulfide (GSSG) - oxidized glutathione - is a disulfide derived from two glutathione molecules. In living cells, glutathione disulfide is reduced into two molecules of glutathione with reducing equivalents from the coenzyme NADPH. This reaction is catalyzed by the enzyme glutathione reductase. [Wikipedia]
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