EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium dextran sulfate
sodium salt of the sulfuric acid ester of dextran

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CAS Number: 9011-18-1
Other:207464-10-6
MDL:MFCD00081551
Category:gelling agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: gel forming agents
viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Dextran sulfate sodium salt
Chemical-navi - Nikkol
DST-H
Odor: characteristic
Use: Anti-swelling agent for face and body; promotes blood circulations by increasing NO production in epidermal cells; clinically-proven slimming effect.
Glentham Life Sciences
Dextran sulfate sodium salt, MW approx. 500,000
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 2350 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979.

oral-mouse LD50 25200 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979.

intravenous-rabbit LD50 19000 mg/kg
Drugs in Japan Vol. 6, Pg. 481, 1982.

intravenous-rat LD50 473 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979.

oral-rat LD50 20600 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Kiso to Rinsho. Clinical Report. Vol. 13, Pg. 1318, 1979.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
gelling agents
Recommendation for sodium dextran sulfate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium dextran sulfate flavor usage levels up to:
 not for flavor use.
 
Safety References:
Chemical Carcinogenesis Research Information System:Search
Carcinogenic Potency Database:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):9011-18-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
Chemidplus:0009011181
RTECS:HH9290000 for cas# 9011-18-1
 
References:
Canada Domestic Sub. List:9011-18-1
Pubchem (sid):135030727
 
Other Information:
HMDB (The Human Metabolome Database):Search
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 dexnon
 dextran sodium sulfate
 dextran sulfate sodium salt
 dextrarine
 DST-H
 sodium salt of the sulfuric acid ester of dextran
 

Articles:

 None found yet.
 
Notes:
a group of glucose polymers made by certain bacteria. dextrans are used therapeutically as plasma volume expanders and anticoagulants. they are also commonly used in biological experimentation and in industry for a wide variety of purposes. long-chain polymer of glucose containing 17-20% sulfur. it has been used as an anticoagulant and also has been shown to inhibit the binding of hiv-1 to cd4-positive t-lymphocytes. it is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
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