asiatic acid
(2a,3b)-2,3,23-trihydroxyurs-12-en-28-oic acid
 
Notes:
triterpene acid.
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(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid (Click)
CAS Number: 464-92-6Picture of molecule
FDA UNII: 9PA5A687X5
Nikkaji Web: J11.338G
MDL: MFCD00238541
XlogP3-AA: 5.70 (est)
Molecular Weight: 488.70856000
Formula: C30 H48 O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: stabilising agents
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 609.45 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 1.170000 mm/Hg @ 25.00 °C. (est)
Flash Point: 638.00 °F. TCC ( 336.40 °C. ) (est)
logP (o/w): 5.748 (est)
Soluble in:
 water, 0.05987 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
stabilising agents
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Suppliers:
Changsha Organic Herb
Centella asiatica Extract
Coompo
For experimental / research use only.
Asiatic Acid from Plants ≥96%
ExtraSynthese
For experimental / research use only.
Asiatic Acid (HPLC) ≥95%
Santa Cruz Biotechnology
For experimental / research use only.
Asiatic Acid
Sigma-Aldrich: Aldrich
For experimental / research use only.
Asiatic Acid 97%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: stabilising agents
Recommendation for asiatic acid usage levels up to:
 not for fragrance use.
 
Recommendation for asiatic acid flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NLM Hazardous Substances Data Bank: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 119034
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
Chemidplus: 0000464926
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References:
 (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 119034
Pubchem (sid): 135075428
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C08617
HMDB (The Human Metabolome Database): Search
FooDB: FDB014909
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
the drug "titrated extract from centella asiatica" (teca), used for its stimulating properties on the healing of wounds, is a mixture of 3 terpenes extracted from a tropical plant: asiatic acid (30%, ww), madecassic acid (30%, ww) and asiaticoside (40%, ww).[maquart fx et al; connect tissue res 24 (2): 107-20 (1990)] pubmed abstract
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 guava
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 guava fruit
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 pomegranate
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 pomegranate flower
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 pomegranate seed
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Synonyms:
 asiaticacid
(1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
(2a,3b)-2,3,23-trihydroxyurs-12-en-28-oic acid
 urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2a,3b,4a)-
 urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2a,3b)-
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Articles:
PubMed: [Triterpenes from aerial parts of Clematoclethra scandens subsp. actinidioides].
PubMed: Microbial transformation of asiatic acid.
PubMed: Development of glutathione-conjugated asiatic acid-loaded bovine serum albumin nanoparticles for brain-targeted drug delivery.
PubMed: Antibacterial effects and action modes of asiatic acid.
PubMed: Biopharmaceutical and pharmacokinetic characterization of asiatic acid in Centella asiatica as determined by a sensitive and robust HPLC-MS method.
PubMed: Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.
PubMed: Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation.
PubMed: Effects of Asiatic Acid on Spatial Working Memory and Cell Proliferation in the Adult Rat Hippocampus.
PubMed: Unusual microbial lactonization and hydroxylation of asiatic acid by Umbelopsis isabellina.
PubMed: Asiatic acid promotes p21(WAF1/CIP1) protein stability through attenuation of NDR1/2 dependent phosphorylation of p21(WAF1/ CIP1) in HepG2 human hepatoma cells.
PubMed: Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats.
PubMed: Evaluation of the anxiolytic and antidepressant effects of asiatic acid, a compound from Gotu kola or Centella asiatica, in the male Sprague Dawley rat.
PubMed: Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents.
PubMed: Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.
PubMed: Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin.
PubMed: Asiatic acid reduces blood pressure by enhancing nitric oxide bioavailability with modulation of eNOS and p47phox expression in L-NAME-induced hypertensive rats.
PubMed: Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model.
PubMed: Glucose uptake through translocation and activation of GLUT4 in PI3K/Akt signaling pathway by asiatic acid in diabetic rats.
PubMed: Antioxidative and antiinflammatory activities of asiatic acid, glycyrrhizic acid, and oleanolic acid in human bronchial epithelial cells.
PubMed: Synthesis and evaluation of asiatic acid derivatives as anti-fibrotic agents: structure/activity studies.
PubMed: Antidiabetic and antihyperlipidemic activity of asiatic acid in diabetic rats, role of HMG CoA: in vivo and in silico approaches.
PubMed: Anti-apoptotic and anti-glycative effects of asiatic acid in the brain of D-galactose treated mice.
PubMed: Unraveling the binding mechanism of asiatic acid with human serum albumin and its biological implications.
PubMed: Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway.
PubMed: Asiatic acid and maslinic acid protected heart via anti-glycative and anti-coagulatory activities in diabetic mice.
PubMed: Asiatic acid attenuates cardiac hypertrophy by blocking transforming growth factor-β1-mediated hypertrophic signaling in vitro and in vivo.
PubMed: Anti-glycative effects of asiatic acid in human keratinocyte cells.
PubMed: Asiatic acid ameliorates hepatic lipid accumulation and insulin resistance in mice consuming a high-fat diet.
PubMed: Synthesis, anti-tumor and anti-angiogenic activity evaluations of asiatic Acid amino Acid derivatives.
PubMed: Mitochondria-dependent apoptosis of con A-activated T lymphocytes induced by asiatic acid for preventing murine fulminant hepatitis.
PubMed: Asiatic acid inhibits adipogenic differentiation of bone marrow stromal cells.
PubMed: Structural analysis of metabolites of asiatic acid and its analogue madecassic acid in zebrafish using LC/IT-MSn.
PubMed: Microbial transformation of asiatic acid.
PubMed: [The protective effect of asiatic acid against oxygen-glucose deprivation/reoxygenation injury of PC12 cells].
PubMed: Neuroprotective effect of asiatic acid in rat model of focal embolic stroke.
PubMed: Asiatic acid protects primary neurons against C2-ceramide-induced apoptosis.
PubMed: Asiatic acid, a triterpene, inhibits cell proliferation through regulating the expression of focal adhesion kinase in multiple myeloma cells.
PubMed: Asiatic acid isolated from Centella asiatica inhibits TGF-β1-induced collagen expression in human keloid fibroblasts via PPAR-γ activation.
PubMed: Asiatic acid ameliorates tubulointerstitial fibrosis in mice with ureteral obstruction.
PubMed: Efficacy of asiatic acid, a pentacyclic triterpene on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-induced diabetic rats.
PubMed: Asiatic acid from Potentilla chinensis attenuate ethanol-induced hepatic injury via suppression of oxidative stress and Kupffer cell activation.
PubMed: Antiproliferative, cell-cycle dysregulation effects of novel asiatic acid derivatives on human non-small cell lung cancer cells.
PubMed: A liquid chromatography/electrospray ionization tandem mass spectrometric method for quantification of asiatic acid from plasma: application to pharmacokinetic study in rats.
PubMed: Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity.
PubMed: Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.
PubMed: Asiatic acid attenuates infarct volume, mitochondrial dysfunction, and matrix metalloproteinase-9 induction after focal cerebral ischemia.
PubMed: Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin-induced diabetic rats.
PubMed: Synthesis and antitumor activity evaluation of new asiatic acid derivatives.
PubMed: Two new oxidation products obtained from the biotransformation of asiatic acid by the fungus Fusarium avenaceum AS 3.4594.
PubMed: Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro.
PubMed: MicroRNA-1290 promotes asiatic acid‑induced apoptosis by decreasing BCL2 protein level in A549 non‑small cell lung carcinoma cells.
PubMed: Effects of asiatic acid on passive and active avoidance task in male Spraque-Dawley rats.
PubMed: Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.
PubMed: Microbial transformation of asiatic acid by Alternaria longipes.
PubMed: Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia.
PubMed: Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade.
PubMed: Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice.
PubMed: Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.
PubMed: Synthesis and biological evaluation of asiatic acid derivatives as inhibitors of glycogen phosphorylases.
PubMed: Protective effects of asiatic acid against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in hepatocytes and kupffer cells co-cultured system via redox-regulated leukotriene C4 synthase expression pathway.
PubMed: Inhibition of LPS-induced NO and PGE2 production by asiatic acid via NF-kappa B inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways.
PubMed: Inhibitory effects of asiatic acid and CPT-11 on growth of HT-29 cells.
PubMed: Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
PubMed: Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
PubMed: Asiatic acid derivatives protect cultured cortical neurons from glutamate-induced excitotoxicity.
PubMed: Inhibition of ultraviolet-A-modulated signaling pathways by asiatic acid and ursolic acid in HaCaT human keratinocytes.
PubMed: Determination of asiatic acid in beagle dog plasma after oral administration of Centella asiatica extract by precolumn derivatization RP-HPLC.
PubMed: Search for a potent microbicidal spermicide from the isolates of Shorea robusta resin.
PubMed: Pharmacokinetics of the total triterpenic fraction of Centella asiatica after single and multiple administrations to healthy volunteers. A new assay for asiatic acid.
PubMed: Protective effects of asiatic acid on rotenone- or H2O2-induced injury in SH-SY5Y cells.
PubMed: Asiatic acid and corosolic acid enhance the susceptibility of Pseudomonas aeruginosa biofilms to tobramycin.
PubMed: Asiatic acid derivatives enhance cognitive performance partly by improving acetylcholine synthesis.
PubMed: Influence of asiatic acid, madecassic acid, and asiaticoside on human collagen I synthesis.
PubMed: Pentacyclic triterpenes combined with ciprofloxacin help to eradicate the biofilm formed in vitro by Escherichia coli.
PubMed: Asiatic acid derivatives protect primary cultures of rat hepatocytes against carbon tetrachloride-induced injury via the cellular antioxidant system.
PubMed: Antinociceptive and anti-inflammatory activities of Schefflera octophylla extracts.
PubMed: Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.
PubMed: In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica.
PubMed: Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acid.
PubMed: Mechanism underlying mitochondrial protection of asiatic acid against hepatotoxicity in mice.
PubMed: Structure-related cytotoxicity and anti-hepatofibric effect of asiatic acid derivatives in rat hepatic stellate cell-line, HSC-T6.
PubMed: Molecular dynamics simulation and thermodynamic modeling of the self-assembly of the triterpenoids asiatic acid and madecassic acid in aqueous solution.
PubMed: Modification of C2 functional group on asiatic acid and the evaluation of hepatoprotective effects.
PubMed: Structure-activity relationship study of asiatic acid derivatives for new wound healing agent.
PubMed: Glioblastoma cell death induced by asiatic acid.
PubMed: Asiatic acid induces apoptosis in SK-MEL-2 human melanoma cells.
PubMed: Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells.
PubMed: Metabolomic analysis of methyl jasmonate-induced triterpenoid production in the medicinal herb Centella asiatica (L.) urban.
PubMed: Centella asiatica in dermatology: an overview.
PubMed: Determination of a new asiatic acid derivative, AS 2-006A in rat plasma and urine, and human plasma by high-performance liquid chromatography.
PubMed: [Simultaneous determination of madecassoside, asiaticoside and their aglycones in Centella asiatica (L.) urban extracts by RP-HPLC].
PubMed: Three pentacyclic triterpenes protect H9c2 cardiomyoblast cells against high-glucose-induced injury.
PubMed: [Separation of asiatic acid by thin-layer chromatography on powdered glass. Determination of asiatic acid on an eluate].
PubMed: [Chemical constitution of asiaticoside and especially of asiatic acid. VI. Inclusion of asiatic acid in the alpha-amyrine series].
PubMed: Inhibition of human enterovirus 71 replication by pentacyclic triterpenes and their novel synthetic derivatives.
PubMed: Chemical constituents from Melastoma dodecandrum and their inhibitory activity on interleukin-8 production in HT-29 cells.
PubMed: [Chemical constituents from the roots of Ilex pubescens].
PubMed: The metabolism of asiatic acid,-madecassic acid and asiaticoside in the rat.
PubMed: [Effects of a triterpene (asiatic acid glycoside) of the amyrine series on plant germination and growth].
PubMed: Studies on bile secretion with the aid of the isolated perfused rat liver. II. The effect of two further pentacyclic triterpenes, asiatic acid and 22beta-angeloyloxyoleanolic acid.
PubMed: [Hormonal action of the "corticosteroid type" of 2 triterpenes: arjunolic acid and asiatic acid].
PubMed: Effect of asiatic and ursolic acids on morphology, hydrophobicity, and adhesion of UPECs to uroepithelial cells.
PubMed: Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products.
PubMed: Protective effect of centella triterpene saponins against cyclophosphamide-induced immune and hepatic system dysfunction in rats: its possible mechanisms of action.
PubMed: Seasonal Variation of Triterpenes and Phenolic Compounds in Australian Centella asiatica (L.) Urb.
PubMed: Factors affecting the content of pentacyclic triterpenes in Centella asiatica raw materials.
PubMed: Nerve Protective Effect of Asiaticoside against Ischemia-Hypoxia in Cultured Rat Cortex Neurons.
PubMed: The comparative steady-state bioavailability of the active ingredients of Madecassol.
PubMed: [Determination of phenols and triterpenoid saponins in stems of Sargentodoxa cuneata].
PubMed: Identification of Major Active Ingredients Responsible for Burn Wound Healing of Centella asiatica Herbs.
PubMed: Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences.
PubMed: [Study on Chemical Constituents from Roots of Lonicera macranthoides].
PubMed: Psiloxylon mauritianum (Bouton ex Hook.f.) Baillon (Myrtaceae): A promising traditional medicinal plant from the Mascarene Islands.
PubMed: In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYP1A2) activity.
PubMed: Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma.
PubMed: Morphological, chemical and molecular characterization of Centella asiatica germplasms for commercial cultivation in the Indo-Gangetic plains.
PubMed: New ursane triterpene from the fruits of Terminalia arjuna.
PubMed: Wound healing activities of different extracts of Centella asiatica in incision and burn wound models: an experimental animal study.
PubMed: Centella asiatica attenuates the neurobehavioral, neurochemical and histological changes in transient focal middle cerebral artery occlusion rats.
PubMed: [Triterpenes from aerial parts of Clematoclethra scandens subsp. actinidioides].
PubMed: Growth inhibition and induction of apoptosis in human cancerous HeLa cells by Maytenus procumbens.
PubMed: Titrated extract of Centella asiatica provides a UVB protective effect by altering microRNA expression profiles in human dermal fibroblasts.
PubMed: Bioavailability, distribution, and antioxidative effects of selected triterpenes in mice.
PubMed: An improved HPLC-UV method for the simultaneous quantification of triterpenic glycosides and aglycones in leaves of Centella asiatica (L.) Urb (APIACEAE).
PubMed: Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer.
PubMed: Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action.
PubMed: Chemical constituents and antibacterial activity of Melastoma malabathricum L.
PubMed: Hepatoprotective activity of Terminalia catappa L. leaves and its two triterpenoids.
PubMed: In vivo antifungal effect of Combretum and Terminalia species extracts on cutaneous wound healing in immunosuppressed rats.
PubMed: Effecting skin renewal: a multifaceted approach.
PubMed: A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-α in activated RAW 264.7 cells.
PubMed: Triterpenoid saponins from Symplocos lancifolia.
PubMed: [Studies on fingerprints of Centella asiatica by HPLC].
PubMed: [Inhibition of three pentacyclic triterpenoids on calcium-induced liver mitochondrial permeability transition in mice].
PubMed: Triterpene composition and bioactivities of Centella asiatica.
PubMed: Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.
PubMed: Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica.
PubMed: [Triterpenoids from leaves of Ilex cornuta].
PubMed: Two new triterpene glycosides from Centella asiatica.
PubMed: Biological activity of two related triterpenes isolated from Combretum nelsonii (Combretaceae) leaves.
PubMed: Association (micellization) and partitioning of aglycon triterpenoids.
PubMed: Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.
PubMed: [Studies on chemical constituents from root of Actinidia macrosperma].
PubMed: [Protective effects of triterpenoids on primarily cultured rat hepatocytes injured by D-galactosamine and carbon tetrachloride].
PubMed: Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.
PubMed: Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids.
PubMed: Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer.
PubMed: Conversion of alpha-amyrin into centellosides by plant cell cultures of Centella asiatica.
PubMed: Contact dermatitis due to Centella asiatica.
PubMed: A new triterpenoid saponin from the stem of Akebia trifoliata var. australis.
PubMed: Antibacterial triterpenes from Syzygium guineense (Myrtaceae).
PubMed: The effects of 10 triterpenoid compounds on experimental liver injury in mice.
PubMed: Comparative phytochemical analysis of Shorea robusta Gaertn (oleoresin) WSR to its seasonal collection.
PubMed: Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors.
PubMed: Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E2, and proinflammatory cytokines in RAW264.7 macrophages.
PubMed: Bioactive pentacyclic triterpenes from the stems of Combretum laxum.
PubMed: Incorporation of triterpenic derivatives within an o/w/o multiple emulsion: structure and release studies.
PubMed: Anti-complementary activity of ursane-type triterpenoids from Weigela subsessilis.
PubMed: Antiproliferative constituents from Umbelliferae plants VII. Active triterpenes and rosmarinic acid from Centella asiatica.
PubMed: Standardisation and Quality Evaluation of Centella asiatica Linn.
PubMed: New innovations in scar management.
PubMed: Triterpenes from Mucuna birdwoodiana.
PubMed: Plant-derived micronutrients suppress monocyte adhesion to cultured human aortic endothelial cell layer by modulating its extracellular matrix composition.
PubMed: Triterpenoid saponin content and the expression level of some related genes in calli of Centella asiatica.
PubMed: A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta.
PubMed: [Triterpenes from herb of Potentilla chinesis].
PubMed: Triterpenes and flavonol glucuronides from Oenothera cheiranthifolia.
PubMed: Topical anti-inflammatory activity of 2alpha-hydroxy pentacyclic triterpene acids from the leaves of Ugni molinae.
PubMed: Inhibitory effect on TNF-alpha-induced IL-8 production in the HT29 cell of constituents from the leaf and stem of Weigela subsessilis.
PubMed: Identification of triterpenoid compounds of Centella asiatica by thin-layer chromatography and mass spectrometry.
PubMed: Advanced formulation and pharmacological activity of hydrogel of the titrated extract of C. asiatica.
PubMed: Evaluation of bioactive saponins and triterpenoidal aglycons for their binding properties on human endothelin ETA and angiotensin AT1 receptors.
PubMed: An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products.
PubMed: Triterpenoids from the leaves of Psidium guajava.
PubMed: Characterization of an ursane triterpenoid from centella asiatica with growth inhibitory activity against spilarctia obliqua.
PubMed: Protective effects of asiaticoside derivatives against beta-amyloid neurotoxicity.
PubMed: Extraction and analysis of cosmetic active ingredients from an anti-cellulitis transdermal delivery system by high-performance liquid chromatography.
PubMed: Regioselective ring opening of steroidal epoxide with hydrides: formation of C(2)- and C(3)-deoxyasiatic acid derivatives.
PubMed: Triterpenoids and their glycosides from the bark of Schefflera octophylla.
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