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disodium 5'-ribonucleotides

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CAS Number: 4691-65-0Picture of molecule3D/inchi
Other(deleted CASRN):133749-71-0
ECHA EINECS - REACH Pre-Reg:225-146-4
FDA UNII: T2ZYA7KC05
CoE Number:11895
Molecular Weight:392.17257056
Formula:C10 H11 N4 Na2 O8 P
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Also(can) Contains:disodium 5'-guanylate
Category:flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Additive: Disodium 5'-Ribonucleotides
GSFA Codex: Disodium 5'-ribonucleotides (635)
DG SANTE Food Additives:disodium 5'-ribonucleotides
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 851.40 °C. @ 760.00 mm Hg (est)
Flash Point: 876.00 °F. TCC ( 468.70 °C. ) (est)
logP (o/w): -1.023 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Description:odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Ajinomoto USA
Ajitide™ Nucleotides
Flavor: characteristic
A premium line of nucleotides with the Ajinomoto touch which unlocks the taste characteristics of foods synergy with glutamates and other flavor enhancers nucleotides have.
Foodchem International
Disodium 5'-Ribonucleotides(I+G)
Graham Chemical
I + G (Disodium 5'-Ribonucleotide
Parchem
disodium 5'-ribonucleotides
Penta International
I + G
Prinova
I+G
Sinofi Food Ingredients
Disodium Ribonucleotides (E635 Flavour Enhancer)
Flavor: characteristic
Flavor Enhancer, Instant Noodle, Pizza, Cheese, Snack Foods, Potato Chip, Crackers, Sauces, Fast Food, Baking Food, Ice Cream, Canned Food, Meats, Poultry, Sauces, Soups, Soft Candy, Puddings, Condiments, Seasonings.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 5400 mg/kg
Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.

intravenous-mouse LD50 3300 mg/kg
Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.

oral-mouse LD50 12000 mg/kg
Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966.

intraperitoneal-rat LD50 4850 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.

intravenous-rat LD50 2730 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.

oral-rat LD50 15900 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.

Dermal Toxicity:
subcutaneous-mouse LD50 5480 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.

subcutaneous-rat LD50 3900 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Ajinomoto Co., Inc. Vol. -, Pg. -, 1973.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor enhancers
Recommendation for disodium 5'-ribonucleotides usage levels up to:
 not for fragrance use.
 
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of disodium 5'-ribonucleotides, disodium 5'-guanylate, disodium 5'-inosinate for all animal species and categories
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):4691-65-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :20819
National Institute of Allergy and Infectious Diseases:Data
disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate
Chemidplus:0004691650
 
References:
 disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:4691-65-0
Pubchem (cid):20819
Pubchem (sid):134984663
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 disodium 5'-O-phosphonatoinosine
 disodium 5'-ribonucleotide
 disodium inosine 5'-monophosphate
 disodium inosine 5'-phosphate
 disodium inosine-5'-monophosphate
 sodium 5'-ribonucleotides
 sodium ribonucleotides
 
 
Notes:
None found
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