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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 92.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 49.00 to 52.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 367.00 to 368.00 °C. @ 760.00 mm Hg
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| Flash Point: | 245.00 °F. TCC ( 118.33 °C. )
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| logP (o/w): | 6.790 (est) |
| Soluble in: |
| | alcohol | | | water, 0.03955 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for manool usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for manool flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 5-(5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpent-1-en-3-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 238792 |
| Pubchem (sid): | 135217579 |
| Pherobase: | View |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (1S-(1alpha(S*), 4abeta,8aalpha))-alpha- | ethenyl decahydro-alpha,5,5,8a-tetramethyl-2-methylene-1-naphthalene propanol | | (13R)- | labda-8(20),14-dien-13-ol | | | labda-8(20),14-dien-13-ol, (13R)- | | | labda-8(20),14-dien-13-ol, (13S)- | | 3- | methyl-5-(5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-yl)-pent-1-en-3-ol | | 3- | methyl-5-(5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl)pent-1-en-3-ol | | 1- | naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(R*),4a.beta.,8a.alpha.]]- | | 1- | naphthalenepropanol, .alpha.-ethenyldecahydro-.alpha.,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4a.beta.,8a.alpha.]]- | | 1- | naphthalenepropanol, a-ethenyldecahydro-a,5,5,8a-tetramethyl-2-methylene- | | 1- | naphthalenepropanol, alpha-ethenyldecahydro-alpha,5,5,8a-tetramethyl-2-methylene- | | 1- | naphthalenepropanol,5,5,8a-tetramethyl-2-methylene-, [1S-[1.alpha.(S*),4a.beta.,8a.alpha.]]- | | 5-(5,5,8a- | trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-methylpent-1-en-3-ol |
Articles:
| PubMed:Synthesis and biological evaluation of ( - )-13,14-dihydroxy-8,11,13-podocarpatrien-7-one and derivatives from (+)-manool. |
| PubMed:Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. |
| PubMed:Chemical constituents of Abies delavayi. |
| PubMed:Facile access to optically active ring C aromatic diterpene derivatives from (+)-manool. first synthesis of 13,14-dihydroxy8,11,13-podocarpatrien-7-one. |
| PubMed:Terpenes From the Root of Salvia hypoleuca Benth. |
| PubMed:Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture. |
| PubMed:(4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho-[2,1-c]pyran (Pyamber). |
| PubMed:Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
| PubMed:Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria. |
| PubMed:Isolation and identification of ligands for the goldfish testis androgen receptor in chemical recovery condensates from a Canadian bleached kraft pulp and paper mill. |
| PubMed:Biota: sediment partitioning of aluminium smelter related PAHs and pulp mill related diterpenes by intertidal clams at Kitimat, British Columbia. |
| PubMed:Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis. |
| PubMed:Influence of ionic interactions on essential oil and phenolic diterpene composition of Dalmatian sage (Salvia officinalis L.). |
| PubMed:Chemical composition and antimicrobial activity of the essential oils from Cleome spinosa. |
| PubMed:Chemical composition of endemic Scorzonera sandrasica and studies on the antimicrobial activity against multiresistant bacteria. |
| PubMed:Extraction, separation and isolation of volatiles from Vitex agnus-castus L. (Verbenaceae) wild species of Sardinia, Italy, by supercritical CO2. |
| PubMed:Antiproliferative activity of Greek propolis. |
| PubMed:Isolation, structure, and bioactivities of abiesadines A-Y, 25 new diterpenes from Abies georgei Orr. |
| PubMed:Variations in essential oil, phenolic compounds, and antioxidant activity of tunisian cultivated Salvia officinalis L. |
| PubMed:Synthesis and antimalarial activities of optically active labdane-type diterpenes. |
| PubMed:Terpenoid constituents of Abies chensiensis with potential anti-inflammatory activity. |
| PubMed:Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry. |
| PubMed:Assessment of some diterpenoids in commercial distilled gin. |
| PubMed:Transformations of manool. tri- and tetracyclic norditerpenoids with in vitro activity against Plasmodium falciparum. |
| PubMed:Chemical composition and antimicrobial activity of volatile components from capitula and aerial parts of Rhaponticum acaule DC growing wild in Tunisia. |
| PubMed:(+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities. |
| PubMed:Facile access to optically active labdane-type diterpenes from (+)-manool. Synthesis of (+)-coronarin E, (+)-15,16-epoxy-8(17),13(16),14-labdatriene, and (+)-labda-8(17),13(Z)-diene-15,16-diol. |
| PubMed:Effect of nitrogen concentration of the nutrient solution on the volatile constituents of leaves of Salvia fruticosa Mill. in solution culture. |
| PubMed:The propolis of stingless bees: terpenes from the tibia of three Frieseomelitta species. |
| PubMed:Essential oils produced by in vitro shoots of sage (Salvia officinalis L.). |
| PubMed:[Chemical constituents from Speranskia tuberculata (Bge.) Baill]. |
| PubMed:Dynamics of yield components and essential oil production in a commercial hybrid sage (Salvia officinalis x Salvia fruticosa cv. Newe Ya'ar no. 4). |
| PubMed:Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. |
| PubMed:Konishiol, a new sesquiterpene, and bioactive components from Cunninghamia konishii. |
| PubMed:Diterpenes from Solidago rugosa. |
| PubMed:Terpenoids from Salvia sclarea. |
| PubMed:Synthesis of manool-related labdane diterpenes as platelet aggregation inhibitors. |
| PubMed:Platelet aggregation inhibitors in a Bhutanese medicinal plant, shug chher. |
| PubMed:Leaf surface chemicals fromNicotiana affecting germination ofPeronospora tabacina (adam) sporangia. |
| PubMed:Chemistry and chemical ecology of the Bahamian spongeAplysilla glacialis. |
| PubMed:Ovipositional response of tobacco budworm moths (Lepidoptera: Noctuidae) to cuticular labdanes and sucrose esters from the green leaves ofNicotiana glutinosa L. (Solanaceae). |
| PubMed:Constituents of Juniperus recurva var. squamata Oil. |
| PubMed:Allelochemical resistance of bald cypress,Taxodium distichum, heartwood to the subterranean termite,Coptotermes formosanus. |
| PubMed:Isolation of (--)-manool from the liverwort, Jungermannia torticalyx. |
| PubMed:[Not Available]. |
| PubMed:[Not Available]. |
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