EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

ethyl 4-methoxycinnamate
3-(4-methoxyphenyl)-2-propenoic acid ethyl ester

Supplier Sponsors

Name:ethyl 3-(4-methoxyphenyl)prop-2-enoate
CAS Number: 1929-30-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:217-679-6
FDA UNII: Search
XlogP3:3.00 (est)
Molecular Weight:206.24118000
Formula:C12 H14 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic UV absorber
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 325.00 to 326.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000235 mmHg @ 25.00 °C. (est)
Flash Point: 273.00 °F. TCC ( 133.80 °C. ) (est)
logP (o/w): 3.020 (est)
Soluble in:
 water, 128.1 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: uv absorbers
Alfa Biotechnology
For experimental / research use only.
Methyl-p-couMaric acid ethyl ester 98%
BOC Sciences
For experimental / research use only.
ethyl p-methoxycinnamate 95%
O'Laughlin Industries
GALANGAL, Ethyl p-Methoxy-cinnamate, 98%
Santa Cruz Biotechnology
For experimental / research use only.
Ethyl 4-methoxycinnamate ≥98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Ethyl 4-methoxycinnamate
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic UV absorber
Recommendation for ethyl 4-methoxycinnamate usage levels up to:
 not for fragrance use.
Recommendation for ethyl 4-methoxycinnamate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :74728
National Institute of Allergy and Infectious Diseases:Data
ethyl 3-(4-methoxyphenyl)prop-2-enoate
 ethyl 3-(4-methoxyphenyl)prop-2-enoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):74728
Pubchem (sid):135031881
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 kaempferia galanga
Search Trop Picture
 ethyl 3-(4-methoxyphenyl)-2-propenoate
 ethyl 3-(4-methoxyphenyl)prop-2-enoate
 ethyl methoxycinnamate
 ethyl p-methoxycinnamate
 ethyl para-methoxycinnamate
4-methoxy cinnamic acid ethyl ester
4-methoxycinnamic acid ethyl ester
3-(4-methoxyphenyl)-2-propenoic acid ethyl ester


PubMed:Ethyl-p-methoxycinnamate isolated from Kaempferia galanga inhibits inflammation by suppressing interleukin-1, tumor necrosis factor-α, and angiogenesis by blocking endothelial functions.
PubMed:Moduratory effect of thai traditional medicine (Yahom Tultavai) on hepatic cytochrome P450 enzymes and pentobarbital-induced sleeping in mice.
PubMed:Hypopigmentary effects of ethyl P-methoxycinnamate isolated from Kaempferia galanga.
PubMed:Antiangiogenic effects and mechanisms of trans-ethyl p-methoxycinnamate from Kaempferia galanga L.
PubMed:Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galanga L. extracts.
PubMed:Ethyl p-methoxycinnamate isolated from a traditional anti-tuberculosis medicinal herb inhibits drug resistant strains of Mycobacterium tuberculosis in vitro.
PubMed:Supercritical carbon dioxide extraction of ethyl p-methoxycinnamate from Kaempferia galanga L. rhizome and its apoptotic induction in human HepG2 cells.
PubMed:Chemical composition and larvicidal activity of edible plant-derived essential oils against the pyrethroid-susceptible and -resistant strains of Aedes aegypti (Diptera: Culicidae).
PubMed:Sedative activity of hexane extract of Keampferia galanga L. and its active compounds.
PubMed:Larvicidal activity of Kaempferia galanga rhizome phenylpropanoids towards three mosquito species.
PubMed:[Study on the anti-carcinogenic effects of three compounds in Kaempferia galanga L].
PubMed:[Studies on the chemical constituents of Securidaca inappendiculata].
PubMed:[Studies on the chemical constituents of Kaempferia marginata].
PubMed:Isolation of Ethyl p-methoxycinnamate, the major antifungal principle of Curcumba zedoaria.
None found
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