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Category:emollients, viscosity controlling
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 1.675e-026 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | emollients, viscosity controlling |
| Recommendation for trierucin usage levels up to: | | | not for fragrance use.
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| Recommendation for trierucin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 2,3-bis[[(Z)-docos-13-enoyl]oxy]propyl (Z)-docos-13-enoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5463075 |
| Pubchem (sid): | 135079172 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2,3-bis[[(Z)- | docos-13-enoyl]oxy]propyl (Z)-docos-13-enoate | | 13- | docosenoic acid, 1,2,3-propanetriyl ester | | | erucic acid triglyceride | | | glycerol trierucate | | | glyceryl trierucate | | | lorenzo oil | | | lorenzo's oil | | | propane-1,2,3-triyl tris((Z)-docos-13 enoate) | | | propane-1,2,3-triyl tris((Z)-docos-13-enoate) | | 1,2,3- | propanetriol tri(13-docosenoate) | | | tri(Z-13-docosenoyl)glycerol |
Articles:
| PubMed:Final report on the safety assessment of trilaurin, triarachidin, tribehenin, tricaprin, tricaprylin, trierucin, triheptanoin, triheptylundecanoin, triisononanoin, triisopalmitin, triisostearin, trilinolein, trimyristin, trioctanoin, triolein, tripalmitin, tripalmitolein, triricinolein, tristearin, triundecanoin, glyceryl triacetyl hydroxystearate, glyceryl triacetyl ricinoleate, and glyceryl stearate diacetate. |
| PubMed:Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. |
| PubMed:Development of ultra-high erucic acid oil in the industrial oil crop Crambe abyssinica. |
| PubMed:A mixture of oleic, erucic and conjugated linoleic acids modulates cerebrospinal fluid inflammatory markers and improve somatosensorial evoked potential in X-linked adrenoleukodystrophy female carriers. |
| PubMed:Cloning and characterization of an acyl-CoA-dependent diacylglycerol acyltransferase 1 (DGAT1) gene from Tropaeolum majus, and a study of the functional motifs of the DGAT protein using site-directed mutagenesis to modify enzyme activity and oil content. |
| PubMed:"Lorenzo's oil" therapy for X-linked adrenoleukodystrophy: rationale and current assessment of efficacy. |
| PubMed:Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil. |
| PubMed:Final report on the safety assessment of trilaurin, triarachidin, tribehenin, tricaprin, tricaprylin, trierucin, triheptanoin, triheptylundecanoin, triisononanoin, triisopalmitin, triisostearin, trilinolein, trimyristin, trioctanoin, triolein, tripalmitin, tripalmitolein, triricinolein, tristearin, triundecanoin, glyceryl triacetyl hydroxystearate, glyceryl triacetyl ricinoleate, and glyceryl stearate diacetate. |
| PubMed:[Endocrine disease in adrenoleukodystrophy]. |
| PubMed:Limnanthes douglasii erucic acid-specific lysophospatidic acid acyltransferase activity in oilseed rape: an analysis of biochemical effects. |
| PubMed:Localized proton magnetic resonance spectroscopy in patients with adult adrenoleukodystrophy. Increase of choline compounds in normal appearing white matter. |
| PubMed:Temporary improvement of neurological symptoms with gammaglobulin therapy in a boy with adrenoleukodystrophy. |
| PubMed:Lysophosphatidic acid acyltransferase from meadowfoam mediates insertion of erucic acid at the sn-2 position of triacylglycerol in transgenic rapeseed oil. |
| PubMed:Adrenoleukodystrophy: magnetic resonance follow-up after Lorenzo's oil therapy. |
| PubMed:Komrower Lecture. Adrenoleukodystrophy: natural history, treatment and outcome. |
| PubMed:Brain, liver, and adipose tissue erucic and very long chain fatty acid levels in adrenoleukodystrophy patients treated with glyceryl trierucate and trioleate oils (Lorenzo's oil). |
| PubMed:Improvement of clinical and MRI findings in a boy with adrenoleukodystrophy by dietary erucic acid therapy. |
| PubMed:Adrenoleukodystrophy in a Chinese boy. |
| PubMed:Triacylglycerol Bioassembly in Microspore-Derived Embryos of Brassica napus L. cv Reston. |
| PubMed:Lysophosphatidate Acyltransferase in the Microsomes from Maturing Seeds of Meadowfoam (Limnanthes alba). |
| PubMed:Substrate specificities of lipases from corn and other seeds. |
| PubMed:Influence of dietary partially hydrogenated vegetable and marine oils on membrane composition and function of liver microsomes and platelets in the rat. |
| PubMed:Lipase in lipid bodies of cotyledons of rape and mustard seedlings. |
| PubMed:[Comparative digestive utilization and forms of fecal excretion in the rat of erucic and brassidic acids esterified in different glyceride structures]. |
| PubMed:Effect of dietary long-chain fatty acids on the rates of cholesterol turnover processes, cholesterol origin and distribution in the rat intestinal lumen. |
| PubMed:Intracellular lipase activities in heart and skeletal muscle homogenates. The absence of trierucin cleavage by the heart: a possible biochemical basis for erucic acid lipidosis. |
| PubMed:[Effects of conjugates of linolenic acid and erucic acid on rat cardiac and liver lipids]. |
| PubMed:Effect of different dietary triglycerides on 7alpha-hydroxylation of cholesterol and other mixed-function oxidations. |
| PubMed:Diet and sterol biohydrogenation in the rat: occurrence of epicoprostanol. |
| PubMed:[Short term comparative study of effects of n-9 trans-docosenoic (brassidic) acid and n-9, cis-docosenoic (erucic) acid on the cardiac lipids of weanling rats]. |
| PubMed:Observations on lipid composition with particular reference to cardiolipin of rat heart after feeding rapeseed oil. |
| PubMed:[Erucic acid metabolism in man and animals: myocardial extraction in man after an overload of rapeseed oil and tissue lipids in the rat after an overload of trierucin]. |
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3D/inchi