EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

propylene di(octanoate)
1-octanoyloxypropan-2-yl octanoate

Supplier Sponsors

Name:1-octanoyloxypropan-2-yl octanoate
CAS Number: 7384-98-7Picture of molecule3D/inchi
Other(deleted CASRN):117657-09-7
ECHA EINECS - REACH Pre-Reg:230-962-9
FDA UNII: 581437HWX2
Nikkaji Web:J106.479G
XlogP3-AA:6.40 (est)
Molecular Weight:328.49272000
Formula:C19 H36 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:solvents/deluents for flavor and/or fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Flavoring:1985 propyleneglycol dioctanoate
FEMA Number:4471 propyleneglycol dioctanoate
FDA:No longer provide for the use of these seven synthetic flavoring substances
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.92300 to 0.92900 @ 20.00 °C.
Pounds per Gallon - (est).: 7.689 to 7.739
Refractive Index:1.43600 to 1.44200 @ 20.00 °C.
Boiling Point: 396.00 to 398.00 °C. @ 760.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:0.000001 mmHg @ 25.00 °C. (est)
Flash Point: 363.00 °F. TCC ( 183.89 °C. )
logP (o/w): 6.688 (est)
Soluble in:
 water, 0.01534 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor Description:fatty fruity
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning - emollient
viscosity controlling agents
BOC Sciences
For experimental / research use only.
Propylene glycol dicaprylate
Chemical-navi - Nikkol
NIKKOL Sefsol-228
Odor: characteristic
Use: Solvent for slightly-soluble active substances; good compatibility with oily materials.
Inoue Perfumery
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
solvents/deluents for flavor and/or fragrance agents
Recommendation for propylene di(octanoate) usage levels up to:
 not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: 3.000007.00000
beverages(nonalcoholic): --
beverages(alcoholic): 0.500001.00000
breakfast cereal: --
cheese: --
chewing gum: 50.00000250.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: 3.000007.00000
fish products: --
frozen dairy: 0.500001.00000
fruit ices: 0.500001.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 10.0000050.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):7384-98-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :94339
National Institute of Allergy and Infectious Diseases:Data
1-octanoyloxypropan-2-yl octanoate
 1-octanoyloxypropan-2-yl octanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7384-98-7
Pubchem (cid):94339
Pubchem (sid):135255988
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
FAO:Propyleneglycol dioctanoate
Potential Blenders and core components note
None Found
Potential Uses:
 viscosity controlling agents
Occurrence (nature, food, other):note
 not found in nature
 aldo DC
 nikkol sefsol-228
 octanoic acid,1,1'-(1-methyl-1,2-ethanediyl) ester
1-octanoyloxypropan-2-yl octanoate
1,2-propane diol dioctanoate
 propane-1,2-diyl dioctanoate
1,2-propanediol dioctanoate
 propylene di(octanoate)
 propylene glycol dicaprylate
 propylene glycol dioctanoate
1,2-propylene glycol dioctanoate
 propyleneglycol dicaprylate
 propyleneglycol dioctanoate
1,2-propyleneglycol dioctanoate


PubMed:Transdermal absorption of natural progesterone from alcoholic gel formulations with hydrophilic surfactant.
PubMed:Studies on the formation of O/W nano-emulsions, by low-energy emulsification method, suitable for cosmeceutical applications.
PubMed:Characterization of semi-solid Self-Emulsifying Drug Delivery Systems (SEDDS) of atorvastatin calcium by Raman image spectroscopy and chemometrics.
PubMed:Effect of hydration on the structure of non aqueous ethyl cellulose/propylene glycol dicaprylate gels.
PubMed:In vitro/in vivo and analytical evaluation of sunless tanning formulations containing different rheology modifiers.
PubMed:Lyotropic, liquid crystalline nanostructures of aqueous dilutions of SMEDDS revealed by small-angle X-ray scattering: impact on solubility and drug release.
PubMed:Impact of emulsion-based drug delivery systems on intestinal permeability and drug release kinetics.
PubMed:Characterization of spreadability of nonaqueous ethylcellulose gel matrices using dynamic contact angle.
PubMed:Investigation of wetting behavior of nonaqueous ethylcellulose gel matrices using dynamic contact angle.
PubMed:Development of novel nonaqueous ethylcellulose gel matrices: rheological and mechanical characterization.
PubMed:Topical delivery of celecoxib using microemulsion.
PubMed:Absorption of transdermally delivered ketorolac acid in humans.
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy