EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

lauryl stearate
octadecanoic acid, dodecyl ester

Supplier Sponsors

CAS Number: 5303-25-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:226-150-9
FDA UNII: 8M9A08VM57
Nikkaji Web:J111.066G
MDL:MFCD00059290
XlogP3-AA:14.10 (est)
Molecular Weight:452.80660000
Formula:C30 H60 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:emollients, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 484.94 °C. @ 760.00 mm Hg (est)
Flash Point: 492.00 °F. TCC ( 255.50 °C. ) (est)
logP (o/w): 14.032 (est)
Soluble in:
 water, 3.259e-009 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
skin conditioning - emollient
 
Suppliers:
BOC Sciences
For experimental / research use only.
lauryl stearate
Santa Cruz Biotechnology
For experimental / research use only.
Dodecyl Stearate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Lauryl Stearate
TCI AMERICA
For experimental / research use only.
Dodecyl Stearate >60.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
emollients, skin conditioning
Recommendation for lauryl stearate usage levels up to:
 not for fragrance use.
 
Recommendation for lauryl stearate flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):5303-25-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :79186
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:nwg
dodecyl octadecanoate
Chemidplus:0005303253
 
References:
 dodecyl octadecanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):79186
Pubchem (sid):135035355
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 emollients
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 dodecyl octadecanoate
 dodecyl stearate
 octadecanoic acid dodecyl ester
 octadecanoic acid, dodecyl ester
 stearic acid dodecyl ester
 stearic acid, dodecyl ester
 

Articles:

PubMed:Effect of olive storage conditions on Chemlali olive oil quality and the effective role of fatty acids alkyl esters in checking olive oils authenticity.
PubMed:Excipient-Process Interactions and their Impact on Tablet Compaction and Film Coating.
PubMed:Lipase immobilized catalytically active membrane for synthesis of lauryl stearate in a pervaporation membrane reactor.
PubMed:Rapid classification of pharmaceutical ingredients with Raman spectroscopy using compressive detection strategy with PLS-DA multivariate filters.
PubMed:Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication.
PubMed:Formulation and evaluation of olanzapine matrix pellets for controlled release.
PubMed:Improving the hardness of dry granulated tablets containing sodium lauryl sulfate.
PubMed:An experimental investigation of the effect of the amount of lubricant on tablet properties.
PubMed:Final report on the safety assessment of sodium cetearyl sulfate and related alkyl sulfates as used in cosmetics.
PubMed:Buccal drug delivery of pravastatin sodium.
PubMed:Comedogenicity in rabbit: some cosmetic ingredients/vehicles.
PubMed:Evidence for vesicle formation from 1:1 nonionic surfactant span 60 and fatty alcohol mixtures in aqueous ethanol: potential delivery vehicle composition.
PubMed:Importance of using physiologically relevant volume of dissolution medium to correlate the oral exposure of formulations of BMS-480188 mesylate.
PubMed:The tandem repeated irritation test: a new method to assess prevention of irritant combination damage to the skin.
PubMed:Unexpected skin barrier influence from nonionic emulsifiers.
PubMed:The impact of formulation and process changes on in vitro dissolution and the bioequivalence of piroxicam capsules.
PubMed:Design and in vivo evaluation of ultrafine inorganic-oxide-containing-sunscreen formulations.
PubMed:The effect of modification of acrylic resins on controlled release and bioadhesion.
PubMed:Effect of cogrinding with various kinds of surfactants on the dissolution behavior of phenytoin.
PubMed:Efficacy of skin barrier creams (IV). The repetitive irritation test (RIT) with a set of 4 standard irritants.
PubMed:Efficacy of skin barrier creams (I). The repetitive irritation test (RIT) in the guinea pig.
PubMed:Bioadhesive dosage form for peroral administration of timolol base.
PubMed:Studies on flufenamic acid capsules and tablets.
PubMed:Effect of shear mixing on in vitro drug release of capsule formulations containing lubricants.
PubMed:The influence of additives on the presentation of a drug in hard gelatin capsules.
PubMed:The in vitro bioavailability of various drugs formulated as hard gelatin capsules.
PubMed:Effect of nonionic surfactants on percutaneous absorption of salicylic acid and sodium salicylate in the presence of dimethyl sulfoxide.
PubMed:Factors effecting drug release from inert matrices. Part 1: effects of surfactants on the release of quinine sulfate.
PubMed:EFFECTS OF PROTEIN, LIPIDS, AND SURFACTANTS ON THE ANTIMICROBIAL ACTIVITY OF SYNTHETIC STEROIDS.
 
Notes:
None found
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