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Category:solvents/deluents for cosmetic and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 sum of isomers
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.86000 @ 25.00 °C.
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| Boiling Point: | 138.00 to 139.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 7.990000 mmHg @ 25.00 °C. |
| Flash Point: | 85.00 °F. TCC ( 29.44 °C. )
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| logP (o/w): | 3.160 |
| Soluble in: |
| | water, 106 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 4300 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
LIVER: OTHER CHANGES
AMA Archives of Industrial Health. Vol. 14, Pg. 387, 1956.
intraperitoneal-rat LD50 2459 mg/kg
Environmental Research. Vol. 40, Pg. 411, 1986.
intravenous-rabbit LDLo 129 mg/kg
Haematologica. Vol. 58, Pg. 491, 1973.
oral-mouse LD50 2119 mg/kg
EHP, Environmental Health Perspectives. Vol. 106
intraperitoneal-mouse LD50 1548 mg/kg
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 18, Pg. 109, 1960.
intraperitoneal-guinea pig LDLo 2000 mg/kg
LIVER: FATTY LIVER DEGERATION
American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974.
oral-human LDLo 50 mg/kg
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.
oral-mammal (species unspecified) LD50 4300 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
intraperitoneal-mammal (species unspecified) LDLo 2000 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: IRRITABILITY
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Hygiene. Vol. 7, Pg. 276, 1927.
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| Dermal Toxicity: |
subcutaneous-rat LD50 1700 mg/kg
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
skin-rabbit LD50 > 1700 mg/kg
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
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| Inhalation Toxicity: |
inhalation-rat LC50 5000 ppm/4H
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
inhalation-guinea pig LCLo 450 ppm
LIVER: FATTY LIVER DEGERATION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Industrial Hygiene. Vol. 10, Pg. 261, 1928.
inhalation-human TCLo 200 ppm
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
inhalation-mammal (species unspecified) LC50 30000 mg/m3
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
inhalation-man LCLo 10000 ppm/6H
BLOOD: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: GENERAL ANESTHETIC
British Medical Journal. Vol. 3, Pg. 442, 1970.
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Safety in Use Information:
| Category: | | solvents/deluents for cosmetic and fragrance agents |
| Recommendation for xylenes isomers plus ethyl benzene usage levels up to: | | | not for fragrance use.
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| Recommendation for xylenes isomers plus ethyl benzene flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| meta-, ortho-, and para- | dimethyl benzene | | m-, o-, and p- | dimethylbenzene | | meta-, ortho-, and para- | dimethylbenzene | | | methyl toluene | | | methyltoluene | | 1,2- | xylene; 1,3-xylene; 1,4-xylene |
Articles:
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a family of isomeric, colorless aromatic hydrocarbon liquids, that contain the general formula c6h4(ch3)2. they are produced by the destructive distillation of coal or by the catalytic reforming of petroleum naphthenic fractions. (from mcgraw-hill dictionary of scientific and technical terms, 5th ed) Xylene is a mixture of three structural isomers of the aromatic hydrocarbon dimethylbenzene:1,2-Dimethylbenzene, 1,3-Dimethylbenzene and 1,4-Dimethylbenzene.
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3D/inchi