EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

stigmasterol
3b-hydroxy-24-ethyl-D5,22-cholestadiene

Supplier Sponsors

Name:(3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
CAS Number: 83-48-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:201-482-7
FDA UNII:99WUK5D0Y8
Nikkaji Web:J4.635C
Beilstein Number:2568182
MDL:MFCD00003630
XlogP3-AA:8.60 (est)
Molecular Weight:412.70076000
Formula:C29 H48 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:food additive, phytosterols
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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DG SANTE Food Additives:stigmasterol-rich plant sterols
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 170.00 °C. @ 760.00 mm Hg
Boiling Point: 501.00 to 502.00 °C. @ 760.00 mm Hg (est)
Flash Point: 427.00 °F. TCC ( 219.40 °C. ) (est)
logP (o/w): 10.072 (est)
Soluble in:
 alcohol
 water, 7.277e-005 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Stigmasterol >98%
Odor: characteristic
Use: Stigmasterol is an unsaturated plant sterol, which may be useful in prevention of certain cancers.
Coompo
For experimental / research use only.
Stigmasterol from Plants ≥96%
Odor: characteristic
Use: Stigmasterol is reported to inhibit cholesterol biosynthesis via inhibition of sterol Delta(24)-reductase in human Caco-2 and HL-60 cell lines. Researchers studied the effect of feeding 0.5% stigmasterol on plasma and liver sterols and intestinal cholesterol and sitosterol absorption in 12 wild-type Kyoto (WKY) and 12 Wistar rats. After 3 weeks of feeding, cholesterol and sitosterol absorption was determined in 6 rats from each group by plasma dual-isotope ratio method. After 3 more weeks, plasma and hepatic sterols and hepatic enzyme activities were determined in all rats. After feeding stigmasterol, baseline plasma cholesterol was 1.3 times and plant sterols 3 times greater in WKY compared with Wistar rats. Stigmasterol feeding lowered plasma cholesterol by approximately 11%, whereas plasma campesterol and sitosterol levels were virtually unchanged in both rat strains, and stigmasterol constituted 3.2% of plasma sterols in WKY rats and 1% in Wistar rats. After 6 weeks of feeding, cholesterol and sitosterol absorption decreased 23% and 30%, respectively, in WKY, and 22% and 16%, respectively, in the Wistar rats as compared with untreated rats. In conclusion, stigmasterol, when fed, lowers plasma cholesterol levels, inhibits intestinal cholesterol and plant sterol absorption, and suppresses hepatic cholesterol and classic bile acid synthesis in Wistar as well as WKY rats. However, plasma and hepatic incorporation of stigmasterol is low. Stigmasterol(Stigmasterin) is used as a precursor in the manufacture of synthetic progesterone, a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids. It is also used as the precursor of vitamin D3. Research has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers.
ExtraSynthese
For experimental / research use only.
Stigmasterol (GC) ≥90%
Santa Cruz Biotechnology
For experimental / research use only.
Stigmasterol ≥95%
Sigma-Aldrich: Sigma
For experimental / research use only.
Stigmasterol ∼95%
Sinoway Industrial
For experimental / research use only.
Stigmasterol
TCI AMERICA
For experimental / research use only.
Stigmasterol >90.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: food additive, phytosterols
Recommendation for stigmasterol usage levels up to:
 not for fragrance use.
 
Recommendation for stigmasterol flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety of stigmasterol-rich plant sterols as food additive
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5280794
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Chemidplus:0000083487
RTECS:WJ2447500 for cas# 83-48-7
 
References:
 (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5280794
Pubchem (sid):134971554
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Metabolomics Database:Search
KEGG (GenomeNet):C05442
HMDB (The Human Metabolome Database):HMDB00937
FooDB:FDB001936
Export Tariff Code:2906.19.5000
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
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 anise seed
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 anise star anise fruit
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 anise tissue culture
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 baboonwood
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 banana fruit
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 barley embryo
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 barley sprout
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 basil leaf
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 basswood wood
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 bean adzuki bean seed
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 bean black bean seed
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 bean fava bean seed
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 bean mung bean seed
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 bean mung bean sprout
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 brussel sprout leaf
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 burdock root
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 cantaloupe seed
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 cardamom seed
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 carob bean seed
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 carrot root
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 celery plant
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 celery seed
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 chamomile german chamomile
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 chamomile sweet false chamomile flower
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 cherimoya seed
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 cherry sour cherry plant
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 chicory
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 cinnamon ceylon cinnamon bark
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 clove fruit
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 coconut seed oil
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 coffee bean
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 coriander fruit
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 corn root
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 corn seed
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 corn seed oil
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 corn shoot
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 corn silk
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 cucumber plant
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 cumin seed
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 dandelion leaf
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 dandelion root
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 date palm fruit
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 deertongue leaf
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 dill plant
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 dill root
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 dill seed oil
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 elder black elder
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 elder black elder flower
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 elder black elder leaf
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 evening-primrose fruit
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 evening-primrose inflorescence
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 fennel seed
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 fennel seed oil
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 fenugreek seed
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 fenugreek tissue culture
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 feverfew flower oil @ trace%
Data GC Search Trop Picture
 fig fruit
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 fig leaf
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 flax seed
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 garlic plant
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 ginger root
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 ginkgo biloba leaf
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 ginkgo biloba pollen
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 goosefoot plant
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 grape plant
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 grape root
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 grape seed
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 guava pineapple guava
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 hazelnut nut
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 hazelnut plant
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 hordeum vulgare l.cv mammut
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 horseradish root
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 lemon fruit
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 lettuce seed
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 mandarin pericarp
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 mandarin root
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 marango seed
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 marchantia convoluta
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 marjoram plant
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 maytenus ilicifolia
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 melon bitter melon fruit
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 melon bitter melon tissue culture
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 mugwort
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 mugwort plant
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 mustard greens leaf
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 nutmeg aril
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 nutmeg seed
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 oat leaf
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 oat seed
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 okra root
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 onion bulb
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 onion seed
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 onion seed oil
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 orange fruit
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 oregano plant
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 papaya seed oil
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 parsley sprout
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 pea black-eyed pea seed
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 pea pigeon pea leaf
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 pea seed
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 peach seed
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 peanut plant
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 pepper bell pepper fruit
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 pepper black pepper
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 pepper black pepper fruit
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 persimmon
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 pineapple fruit
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 pistachio nut
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 pomegranate seed
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 poppy opium poppy seed
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 potato tuber
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 rapini leaf
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 rapini root
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 rice juice
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 rosemary shoot
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 sage
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 sage fruit oil
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 sage leaf
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 savory summer savory plant
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 savory winter savory leaf
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 sesame seed
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 sesame seed oil
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 shea tree seed
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 soursop plant
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 soybean seed
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 soybean seed oil
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 spearmint shoot
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 sunflower seed
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 tarragon plant
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 tea seed oil
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 thyme leaf
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 tomato fruit
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 turmeric rhizome
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 turmeric root
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 walnut black walnut fruit
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 walnut english walnut nut
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 watermelon seed
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 watermelon seed oil
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Synonyms:
14-((2E)(4S,1R)-4-ethyl-1,5-dimethylhex-2-enyl)(1S,5S,10S,11S,2R,14R,15R)-2,15 -dimethyltetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol
14-((2E)(4S,1R)-4-ethyl-1,5-dimethylhex-2-enyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyltetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol
(3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
 guinea-pig-anti-stiffness factor
3b-hydroxy-24-ethyl-D5,22-cholestadiene
(3b,22E)-stigmasta-5,22-dien-3-ol
(24S)-5,22-stigmastadien-3b-ol
(24S)-5,22-stigmastadien-3beta-ol
 stigmasterol-rich plant sterols
 

Articles:

PubMed:The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin - A biochemical study in rats subjected to experimental hyperlipidemia and obesity.
PubMed:Determination of tocopherols and sitosterols in seeds and nuts by QuEChERS-liquid chromatography.
PubMed:Phytosterols in onion contribute to a sensation of lingering of aroma, a koku attribute.
PubMed:Adequacy of the measurement capability of fatty acid compositions and sterol profiles to determine authenticity of milk fat through formulation of adulterated butter.
PubMed:Sterol Composition in Infant Formulas and Estimated Intake.
PubMed:7keto-stigmasterol and 7keto-cholesterol induce differential proteome changes to intestinal epitelial (Caco-2) cells.
PubMed:Comparative inhibitory potential of selected dietary bioactive polyphenols, phytosterols on CYP3A4 and CYP2D6 with fluorometric high-throughput screening.
PubMed:Stigmasterol protects against Ang II-induced proliferation of the A7r5 aortic smooth muscle cell-line.
PubMed:Subcritical extraction of flaxseed oil with n-propane: Composition and purity.
PubMed:Physicochemical analysis of Psophocarpus tetragonolobus (L.) DC seeds with fatty acids and total lipids compositions.
PubMed:Chlorophyta and Rhodophyta macroalgae: a source of health promoting phytochemicals.
PubMed:Effect of water, metallic ions, fatty acid and temperature on oxidative stability of 1-octacosanol from sugarcane rind.
PubMed:Direct saponification preparation and analysis of free and conjugated phytosterols in sugarcane (Saccharum officinarum L.) by reversed-phase high-performance liquid chromatography.
PubMed:Cholesterol and stigmasterol within a sunflower oil matrix: Thermal degradation and oxysterols formation.
PubMed:Analysis of triterpenoids and phytosterols in vegetables by thin-layer chromatography coupled to tandem mass spectrometry.
PubMed:An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system.
PubMed:Characterization and quantification of γ-oryzanol in grains of 16 Korean rice varieties.
PubMed:Comparative evaluation of two Trichoderma harzianum strains for major secondary metabolite production and antifungal activity.
PubMed:Characterization of glyceridic and unsaponifiable compounds of Sacha inchi (Plukenetia huayllabambana L.) oils.
PubMed:Prevention of renal dysfunction by nutraceuticals prepared from oil rich plant foods.
PubMed:Plants Fagonia cretica L. and Hedera nepalensis K. Koch contain natural compounds with potent dipeptidyl peptidase-4 (DPP-4) inhibitory activity.
PubMed:Analysis of phytosterols and phytostanols in enriched dairy products by Fast gas chromatography with mass spectrometry.
PubMed:Changes in the triterpenoid content of cuticular waxes during fruit ripening of eight grape (Vitis vinifera) cultivars grown in the Upper Rhine Valley.
PubMed:Diet micronutrient balance matters: How the ratio of dietary sterols/steroids affects development, growth and reproduction in two lepidopteran insects.
PubMed:24(S)-Saringosterol from edible marine seaweed Sargassum fusiforme is a novel selective LXRβ agonist.
PubMed:Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats.
PubMed:Extraction optimization by response surface methodology: Purification and characterization of phytosterol from sugarcane (Saccharum officinarum L.) rind.
PubMed:The bone regenerative effects of fucosterol in in vitro and in vivo models of postmenopausal osteoporosis.
PubMed:Characterization of oilseed lipids from "DHA-producing Camelina sativa": a new transformed land plant containing long-chain omega-3 oils.
PubMed:Seasonal variation of vitamin and sterol content of chironomidae larvae.
PubMed:Recent advances in Phytosterol Oxidation Products.
PubMed:Isolation and characterization of steroids, phthalide and essential oil of the fruits of Kelussia odoratissima Mozaff., an endemic mountain celery.
PubMed:Effect of ultra high pressure homogenization treatment on the bioactive compounds of soya milk.
PubMed:Phytochemical contents and antioxidant capacities of different parts of two sugarcane (Saccharum officinarum L.) cultivars.
PubMed:Algal sterols are as effective as β-sitosterol in reducing plasma cholesterol concentration.
PubMed:New triterpenoids and other constituents from the fruits of Benincasa hispida (Thunb.) Cogn.
PubMed:Quality and characteristics of ginseng seed oil treated using different extraction methods.
PubMed:Bioassay guided isolation and identification of anti-inflammatory active compounds from the root of Ficus formosana.
PubMed:Wheat straw biomass: a resource for high-value chemicals.
PubMed:Vitiquinolone--a quinolone alkaloid from Hibiscus vitifolius Linn.
PubMed:Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes.
PubMed:Kinetics and molecular docking studies of an anti-diabetic complication inhibitor fucosterol from edible brown algae Eisenia bicyclis and Ecklonia stolonifera.
PubMed:Phytosterols in grapes and wine, and effects of agrochemicals on their levels.
PubMed:Lipophilic extracts of Cynara cardunculus L. var. altilis (DC): a source of valuable bioactive terpenic compounds.
PubMed:Pentadecyl ferulate, a potent antioxidant and antiproliferative agent from the halophyte Salicornia herbacea.
PubMed:Sacha inchi (Plukenetia volubilis): a seed source of polyunsaturated fatty acids, tocopherols, phytosterols, phenolic compounds and antioxidant capacity.
PubMed:Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264.7 macrophages.
PubMed:Nematicidal activity of nonacosane-10-ol and 23a-homostigmast-5-en-3β-ol isolated from the roots of Fumaria parviflora (Fumariaceae).
PubMed:A rapid method to determine sterol, erythrodiol, and uvaol concentrations in olive oil.
PubMed:Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells.
PubMed:Common sources and composition of phytosterols and their estimated intake by the population in the city of São Paulo, Brazil.
PubMed:Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines.
PubMed:Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters.
PubMed:Novel synthesis strategy for the preparation of individual phytosterol oxides.
PubMed:Comparative seasonal sterol profiles in edible parts of Mediterranean fish and shellfish species.
PubMed:Preparation of nano/submicrometer yam and its benefits on collagen secretion from skin fibroblast cells.
PubMed:Red ginseng marc oil inhibits iNOS and COX-2 via NFκB and p38 pathways in LPS-stimulated RAW 264.7 macrophages.
PubMed:Triterpenoid content of berries and leaves of bilberry Vaccinium myrtillus from Finland and Poland.
PubMed:Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation.
PubMed:Fucosterol is a selective liver X receptor modulator that regulates the expression of key genes in cholesterol homeostasis in macrophages, hepatocytes, and intestinal cells.
PubMed:Dietary phosphilipids and sterols protective against peptic ulceration.
PubMed:Sterols and triterpene diols in olive oil as indicators of variety and degree of ripening.
PubMed:A single extraction and HPLC procedure for simultaneous analysis of phytosterols, tocopherols and lutein in soybeans.
PubMed:Fucosterol isolated from Undaria pinnatifida inhibits lipopolysaccharide-induced production of nitric oxide and pro-inflammatory cytokines via the inactivation of nuclear factor-κB and p38 mitogen-activated protein kinase in RAW264.7 macrophages.
PubMed:Sterols heating: degradation and formation of their ring-structure polar oxidation products.
PubMed:Polyamine conjugates of stigmasterol.
PubMed:Evaluation of the cytotoxic effect of 7keto-stigmasterol and 7keto-cholesterol in human intestinal (Caco-2) cells.
PubMed:Characterization of high-value bioactives in some selected varieties of Pakistani Rice (Oryza sativa L.).
PubMed:Oxidized derivatives of dihydrobrassicasterol: cytotoxic and apoptotic potential in U937 and HepG2 cells.
PubMed:Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells.
PubMed:Comparison of the triterpenoid content of berries and leaves of lingonberry Vaccinium vitis-idaea from Finland and Poland.
PubMed:Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.
PubMed:Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59.
PubMed:Stigmasterol-based novel low molecular weight/mass organic gelators.
PubMed:Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé.
PubMed:Phytosterols: perspectives in human nutrition and clinical therapy.
PubMed:Chemical composition and biological activity of Citrus jambhiri Lush.
PubMed:Chemical composition and nutritional value of unripe banana flour (Musa acuminata, var. Nanicão).
PubMed:Effect of phytosterols and their oxidation products on lipoprotein profiles and vascular function in hamster fed a high cholesterol diet.
PubMed:Antidermatophytic and Toxicological Evaluations of Dichloromethane-Methanol Extract, Fractions and Compounds Isolated from Coula edulis.
PubMed:High-speed counter-current chromatographic separation of phytosterols.
PubMed:Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
PubMed:Separation and purification of ergosterol and stigmasterol in Anoectochilus roxburghii (wall) Lindl by high-speed counter-current chromatography.
PubMed:Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line.
PubMed:Commercial peanut (Arachis hypogaea L.) cultivars in the United States: phytosterol composition.
PubMed:Chemistry and antioxidant activity of essential oil and oleoresins of black caraway (Carum bulbocastanum) fruits: Part 69.
PubMed:Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
PubMed:[Comparison of the dietary phytosterols intake and serum lipids content in elderly women from three cities of China].
PubMed:Free and glycosylated sterol bioaccumulation in developing Cycas micronesica seeds.
PubMed:Anti-inflammatory activity of new compounds from Andrographis paniculata by NF-kappaB transactivation inhibition.
PubMed:Synthesis and characterization of stigmasterol oxidation products.
PubMed:Sterols isolated from Nuruk (Rhizopus oryzae KSD-815) inhibit the migration of cancer cells.
PubMed:Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum.
PubMed:The effects of corn silk on glycaemic metabolism.
PubMed:Effect of the solvent type and temperature on phytosterol contents and compositions of wheat straw, bran, and germ extracts.
PubMed:Antiproliferation properties of grain sorghum dry distiller's grain lipids in Caco-2 cells.
PubMed:Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography.
PubMed:[Analysis of phytosterol contents in food plant materials and Chinese traditional medicines].
PubMed:Analysis of phytosterols in extra-virgin olive oil by nano-liquid chromatography.
PubMed:Identification and assessment of antioxidant capacity of phytochemicals from kiwi fruits.
PubMed:Miscanthus x giganteus extractives: a source of valuable phenolic compounds and sterols.
PubMed:Enzymatic production of trans-free hard fat stock from fractionated rice bran oil, fully hydrogenated soybean oil, and conjugated linoleic Acid.
PubMed:Contents of phytosterols in vegetables and fruits commonly consumed in China.
PubMed:[Foods fortified with phytosterins: their role in decreasing serum cholesterol level, their European Community authorization and requirements for placing them on the market].
PubMed:Bioactive metabolites from Spilanthes acmella Murr.
PubMed:Nutritional traits of bean ( Phaseolus vulgaris ) seeds from plants chronically exposed to ozone pollution.
PubMed:Sterolic composition of Chétoui virgin olive oil: Influence of geographical origin.
PubMed:Ripening-specific stigmasterol increase in tomato fruit is associated with increased sterol C-22 desaturase (CYP710A11) gene expression.
PubMed:Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1.
PubMed:Sterol oxidation in ready-to-eat infant foods during storage.
PubMed:Pomegranate oil analysis with emphasis on MALDI-TOF/MS triacylglycerol fingerprinting.
PubMed:Safety tests and antinutrient analyses of noni (Morinda citrifolia L.) leaf.
PubMed:[Analysis of phytosterol contents in Chinese plant food and primary estimation of its intake of people].
PubMed:Identification of beta-sitosterol, stigmasterol and ergosterin in A. roxburghii using supercritical fluid extraction followed by liquid chromatography/atmospheric pressure chemical ionization ion trap mass spectrometry.
PubMed:Oxidation products of stigmasterol interfere with the action of the female sex hormone 17beta-estradiol in cultured human breast and endometrium cell lines.
PubMed:Food sources of plant sterols in the EPIC Norfolk population.
PubMed:Concentration of sterols of Porphyridium cruentum biomass at stationary phase.
PubMed:Separation and determination of diversiform phytosterols in food materials using supercritical carbon dioxide extraction and ultraperformance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
PubMed:Sterol composition of freshwater algivorous ciliates does not resemble dietary composition.
PubMed:Fatty acid profile, tocopherol, squalene and phytosterol content of brazil, pecan, pine, pistachio and cashew nuts.
PubMed:Quantitation of fatty acids, sterols, and tocopherols in turpentine (Pistacia terebinthus Chia) growing wild in Turkey.
PubMed:Antioxidant and antimutagenic properties of Hibiscus tiliaceus L. methanolic extract.
PubMed:Protection against esophageal cancer in rodents with lyophilized berries: potential mechanisms.
PubMed:Common sources and estimated intake of plant sterols in the Spanish diet.
PubMed:Effects of diet and metamorphosis upon the sterol composition of the butterfly Morpho peleides.
PubMed:Intakes of selected nutrients, foods, and phytochemicals and prostate cancer risk in western New York.
PubMed:Levels of phytosterol oxides in enriched and nonenriched spreads: application of a thin-layer chromatography-gas chromatography methodology.
PubMed:Glucosinolates and fatty acid, sterol, and tocopherol composition of seed oils from Capparis spinosa Var. spinosa and Capparis ovata Desf. Var. canescens (Coss.) Heywood.
PubMed:Margarine phytosterols decrease the secretion of atherogenic lipoproteins from HepG2 liver and Caco2 intestinal cells.
PubMed:Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, Dioscorea polygonoides.
PubMed:Beta-sitosterol from psyllium seed husk (Plantago ovata Forsk) restores gap junctional intercellular communication in Ha-ras transfected rat liver cells.
PubMed:[Therapeutic effects of phytosterols and phytostanols in cholesterolemia].
PubMed:Separation of phytosterol oxidation products by combination of different polarity gas chromatography capillary columns.
PubMed:Four new prenylated isoflavonoids in Tadehagi triquetrum.
PubMed:Capillary electrochromatography of sterols and related steryl esters derived from vegetable oils.
PubMed:Estimation of plant sterol and cholesterol intake in Finland: quality of new values and their effect on intake.
PubMed:Secondary metabolites from the leaves of Feijoa sellowiana Berg.
PubMed:Effects of sterol structure, temperature, and lipid medium on phytosterol oxidation.
PubMed:Amaranth as a rich dietary source of beta-sitosterol and other phytosterols.
PubMed:Characterization of carrot root oil arising from supercritical fluid carbon dioxide extraction.
PubMed:Gas chromatographic separation and mass spectrometric identification of mixtures of oxyphytosterol and oxycholesterol derivatives application to a phytosterol-enriched food.
PubMed:Fatty acid profile, tocopherol, squalene and phytosterol content of walnuts, almonds, peanuts, hazelnuts and the macadamia nut.
PubMed:Inhibition of stigmasterol oxidation by antioxidants in purified sunflower oil.
PubMed:Impact of 10 dietary sterols on growth and reproduction of Daphnia galeata.
PubMed:Phytosterol composition of hybrid Hibiscus seed oils.
PubMed:Influence of agronomic variables on the composition of mate tea leaves (Ilex paraguariensis) extracts obtained from CO2 extraction at 30 degrees C and 175 bar.
PubMed:Extraction and characterization of volatile compounds in Maytenus ilicifolia, using high-pressure CO2.
PubMed:Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals.
PubMed:Phytosterols: lack of cytotoxicity but interference with beta-carotene uptake in Caco-2 cells in culture.
PubMed:Preparation and mass spectrometry of 14 pure and 18O(2)-labeled oxidation products from the phytosterols beta-sitosterol and stigmasterol.
PubMed:A plant food-based diet modifies the serum beta-sitosterol concentration in hyperandrogenic postmenopausal women.
PubMed:Sterol ferulates, sterols, and 5-alk(en)ylresorcinols from wheat, rye, and corn bran oils and their inhibitory effects on Epstein-Barr virus activation.
PubMed:Phytonutrient deficiency: the place of palm fruit.
PubMed:Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy.
PubMed:Risk of human ovarian cancer is related to dietary intake of selected nutrients, phytochemicals and food groups.
PubMed:Presence of phytosterol oxides in crude vegetable oils and their fate during refining.
PubMed:Antioxidant constituents of almond [Prunus dulcis (Mill.) D.A. Webb] hulls.
PubMed:Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation.
PubMed:Expression of a Streptomyces 3-hydroxysteroid oxidase gene in oilseeds for converting phytosterols to phytostanols.
PubMed:A single daily dose of soybean phytosterols in ground beef decreases serum total cholesterol and LDL cholesterol in young, mildly hypercholesterolemic men.
PubMed:Elution behavior of unsaponifiable lipids with various capillary electrochromatographic stationary phases.
PubMed:Classification and class-modeling of "Riviera Ligure" extra-virgin olive oil using chemical-physical parameters.
PubMed:Phytosterol content in American ginseng seed oil.
PubMed:Apianane terpenoids from Salvia officinalis.
PubMed:[Residual chemicals in natural rubber products for food contact use].
PubMed:Biosynthesis of the hemi- and monoterpene moieties of isoprenyl phenyl ethers from the liverwort Trichocolea tomentella.
PubMed:Fatty acid steryl, stanyl, and steroid esters by esterification and transesterification in vacuo using Candida rugosa lipase as catalyst.
PubMed:Analysis of olive and hazelnut oil mixtures by high-performance liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry of triacylglycerols and gas-liquid chromatography of non-saponifiable compounds (tocopherols and sterols).
PubMed:The safety evaluation of phytosterol esters. Part 6. The comparative absorption and tissue distribution of phytosterols in the rat.
PubMed:Relation of acidity and sensory quality with sterol content of olive oil from stored fruit.
PubMed:Chemical composition of some wild peanut species (Arachis L.) seeds.
PubMed:Safety evaluation of phytosterol esters. Part 5. Faecal short-chain fatty acid and microflora content, faecal bacterial enzyme activity and serum female sex hormones in healthy normolipidaemic volunteers consuming a controlled diet either with or without a phytosterol ester-enriched margarine.
PubMed:Mass spectrometry characterization of the 5alpha-, 7alpha-, and 7beta-hydroxy derivatives of beta-sitosterol, campesterol, stigmasterol, and brassicasterol.
PubMed:Characterization of Moringa oleifera variety Mbololo seed oil of Kenya.
PubMed:Analytical evaluation of virgin olive oil of first and second extraction.
PubMed:Safety evaluation of phytosterol esters. Part 4. Faecal concentrations of bile acids and neutral sterols in healthy normolipidaemic volunteers consuming a controlled diet either with or without a phytosterol ester-enriched margarine.
PubMed:Safety evaluation of phytosterol esters. Part 1. Assessment of oestrogenicity using a combination of in vivo and in vitro assays.
PubMed:Acid-catalyzed isomerization of fucosterol and delta5-avenasterol.
PubMed:Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hypercholesterolaemic subjects.
PubMed:[An epidemic of asthma caused by soybean in L'Hospitalet de Llobregat (Barcelona)].
PubMed:A marked and sustained reduction in LDL sterols by diet and cholestyramine in beta-sitosterolemia.
PubMed:Simplified gas chromatographic method for the simultaneous determination of phytosterols and cholesterol.
PubMed:Capillary gas-liquid chromatography of faecal free and esterified neutral sterols.
PubMed:Further investigations of mutagenic cholesterol preparations.
PubMed:Isolation of two new C30 sterols, (24E)-24-N-propylidenecholesterol and 24 epsilon-N-propylcholesterol, from a cultured marine Chrysophyte.
PubMed:Determination of the sterol composition of diets used in dietary management of hyperlipoproteinemia.
PubMed:Axenic Paramecium caudatum. I. Mass culture and structure.
PubMed:Sterol content of foods of plant origin.
PubMed:Gas-liquid chromatographic determination of cholesterol and other sterols in foods.
PubMed:Sterol composition of butters and margarines.
PubMed:Plasma and dietary phytosterols in children.
PubMed:Unsaponifiable matter of crude and processed coconut oil.
PubMed:Phytosterols of Cannibas smoke.
PubMed:Quantitative changes in some unsaponifiable components of soya bean oil due to refining.
PubMed:Fat characteristics and stability of nondairy and dairy powdered creamers.
 
Notes:
Stigmasterol is an unsaturated plant sterol occurring in the plant fats or oils of soybean, calabar bean, and rape seed, and in a number of medicinal herbs, including the Chinese herbs Ophiopogon japonicus (Mai men dong) and American Ginseng. Stigmasterol is also found in various vegetables, legumes, nuts, seeds, and unpasteurized milk. (Wikipedia)
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