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      Product(s):
      SODIUM BISULFITE GRANULAR FCC, Kosher
       
sodium bisulfite
Notes :
has been used externally for parasitic skin diseases and as gastrointestinal antiseptic.
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  • Organoleptics
      • Organoleptic Properties
  • Properties
      • Physical Properties
        Appearance :white crystalline powder (est)
        Assay : 85.00 to 100.00 % 
        Food Chemicals Codex Listed :No
        Specific Gravity :1.48000 @  25.00 °C.
  • Safety
      • Safety Information
        Oral/Parenteral Toxicity : 
          intravenous-rat LD50  115 mg/kg
        LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
        Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.

        intraperitoneal-rat LD50  475 mg/kg
        BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        Proceedings of the National Academy of Sciences of the United States of America. Vol. 70, Pg. 3655, 1973.

        intravenous-rabbit LD50  65 mg/kg
        LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.

        intraperitoneal-rabbit LD50  300 mg/kg
        LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS
        Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.

        intravenous-mouse LD50  130 mg/kg
        LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.

        intraperitoneal-mouse LD50  675 mg/kg
        LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
        Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.

        intraperitoneal-dog LD50  244 mg/kg
        LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        Clinical Pharmacology and Therapeutics Vol. 9, Pg. 328, 1968.

        intraperitoneal-guinea pig LD50  779 mg/kg
        Toxicology and Applied Pharmacology. Vol. 44, Pg. 251, 1978.

        intraperitoneal-hamster LD50  487 mg/kg
        Ceskoslovenska Hygiena. Czechoslovak Hygiene. Vol. 22, Pg. 64, 1977.

        intravenous-hamster LD50  95 mg/kg
        LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 101, 1951.

        oral-rat LD50  2000 mg/kg
        "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 1408, 1991.

        Dermal Toxicity : 
          Not determined
        Inhalation Toxicity : 
          Not determined
  • Safety in Use
      • Safety in Use Information
        Category :antibrowning agents, antioxidants, preservatives
        Recommendation for sodium bisulfite fragrance usage levels up to :
         not for fragrance use.
        Recommendation for sodium bisulfite flavor usage levels up to :
         not for flavor use.
  • Safety References
sodium sulfite (Click)
CAS Number : 7631-90-5
ESIS EC# (EINECS) :231-548-0
Molecular Weight :105.06884930
Formula :Na O3 S -
BioActivity Summary :listing
NMR Predictor :Predict
Category :antibrowning agents, antioxidants, preservatives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
Google Scholar : Search Google Books : Search
Google Scholar : with word "volatile"Search Google Scholar : with word "flavor"Search
Google Scholar : with word "odor"SearchPerfumer and Flavorist : Search
Google Patents : Search US Patents : Search
EU Patents : Search
Pubchem Patents:Search
PubMed : SearchNCBI : Search
 FDA/EU SANCO Petitions, Reviews, Notices :
182.3739 Sodium bisulfite View-review
EU SANCO Sulphur dioxide - sulphites View-review
EU SANCO Sodium hydrogen sulphite View-review
JECFA Food Additive : Sodium Hydrogen Sulfite
GSFA Codex : Sodium hydrogen sulfite (222).
FDA Mainterm : SODIUM BISULFITE
FDA Regulation :FDA PART 161 -- FISH AND SHELLFISH
Subpart B--Requirements for Specific Standardized Fish and Shellfish
Sec. 161.173 Canned wet pack shrimp in transparent or nontransparent containers.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.310 Boiler water additives.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart D--Chemical Preservatives
Sec. 182.3739 Sodium bisulfite.
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Picture of molecule
sodium sulfite
Synonyms :
 hydrogen sodium sulfite
 sodium bisulphite
 sodium hydrogen sulfite
 sodium hydrogen sulphite
 sodium sulfite (1:1)
 sulfurous acid monosodium salt
 sulfurous acid sodium salt (1:1)
 sulfurous acid, sodium salt (1:1)
Soluble in :
 water, 1e+006 mg/L @ 25 °C (est)
 alcohol, slightly
Stability :
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