EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

polydimethyl siloxane
poly(oxy(dimethylsilylene))

Sponsors

CAS Number: 9016-00-6Picture of molecule3D/inchi
MDL:MFCD00084411
Molecular Weight:74.15432000
Formula:C2 H6 O Si
NMR Predictor:Predict (works with chrome or firefox)
Category:antifoaming (or defoaming) agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
JECFA Food Additive: Polydimethylsiloxane
GSFA Codex: Polydimethylsiloxane (900a)
FDA Mainterm: DIMETHYLPOLYSILOXANE
FDA Regulation:
FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.180 Canned pineapple.


FDA PART 146 -- CANNED FRUIT JUICES
Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.185 Pineapple juice.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.340 Defoaming agents.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.180 Components of paper and paperboard in contact with dry food.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.200 Defoaming agents used in coatings.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.210 Defoaming agents used in the manufacture of paper and paperboard.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2260 Filters, resin-bonded.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2800 Textiles and textile fibers.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3570 Lubricants with incidental food contact.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3910 Surface lubricants used in the manufacture of metallic articles.


FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS
Subpart B--Specific Prior-Sanctioned Food Ingredients
Sec. 181.28 Release agents.
 
Physical Properties:
Food Chemicals Codex Listed: No
Flash Point: 275.00 °F. TCC ( 135.00 °C. )
Soluble in:
 water, 0.004528 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antifoaming agents
emollients
skin conditioning
skin protecting agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Polydimethylsiloxane 95%
Sigma-Aldrich: Sigma
For experimental / research use only.
Dimethylpolysiloxane viscosity 5 cSt (25 °C)(lit.)
Sigma-Aldrich: Sigma
For experimental / research use only.
Dimethylpolysiloxane viscosity 500 cSt (25 °C)(lit.)
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-dog LD > 410 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

intraperitoneal-mouse LD > 5500 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

intraperitoneal-rat LD > 2000 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

Dermal Toxicity:
subcutaneous-dog LD > 410 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

subcutaneous-mouse LD > 5500 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

subcutaneous-rat LD > 2000 mg/kg
Antibiotiki i Khimioterapiya. Antibiotics and Chemotherapy. Vol. 33, Pg. 666, 1988.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: antifoaming (or defoaming) agents
Recommendation for polydimethyl siloxane usage levels up to:
 not for fragrance use.
 
Recommendation for polydimethyl siloxane flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
NLM Developmental and Reproductive Toxicity:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24771
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
dimethyl(oxo)silane
Chemidplus:0009016006
EPA/NOAA CAMEO:hazardous materials
RTECS:9016-00-6
 
References:
 dimethyl(oxo)silane
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):24771
Pubchem (sid):134989538
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:3910.00.0000
Haz-Map:View
Household Products:Search
ChemSpider:View
FAO:POLYDIMETHYLSILOXANE
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 antifoam FD 62
 dimethyl(oxo)silane
 dimethylpolysiloxane
 dow corning 346
 poly(dimethyl siloxane)
 poly(dimethylsiloxane)
 poly(oxy(dimethylsilylene))
 polydimethylsiloxane
 

Articles:

Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed:A simple method for patterning poly(dimethylsiloxane) barriers in paper using contact-printing with low-cost rubber stamps.
PubMed:Silicone surface with drug nanodepots for medical devices.
PubMed:A novel biosensor array with a wheel-like pattern for glucose, lactate and choline based on electrochemiluminescence imaging.
PubMed:Solid-phase microextraction in targeted and nontargeted analysis: displacement and desorption effects.
PubMed:╬╝PIV methodology using model systems for flow studies in heterogeneous biopolymer gel microstructures.
PubMed:Determination of estrogens in pork and chicken samples by stir bar sorptive extraction combined with high-performance liquid chromatography-ultraviolet detection.
PubMed:Determination of trimethylamine in spinach, cabbage, and lettuce at alkaline pH by headspace solid-phase microextraction.
PubMed:Removal of organic compounds from water by using a gold nanoparticle-poly(dimethylsiloxane) nanocomposite foam.
PubMed:Ecotoxicological effects of an aged TiO2 nanocomposite measured as apoptosis in the anecic earthworm Lumbricus terrestris after exposure through water, food and soil.
PubMed:Aptamer-based PDMS-gold nanoparticle composite as a platform for visual detection of biomolecules with silver enhancement.
PubMed:Integration of ground aerogel particles as chromatographic stationary phase into microchip.
PubMed:Evaluation of certain food additives and contaminants.
PubMed:Solid-phase microextraction followed by gas chromatography-mass spectrometry for the determination of ink photo-initiators in packed milk.
PubMed:Single-walled carbon nanotubes coated fibers for solid-phase microextraction and gas chromatography-mass spectrometric determination of pesticides in Tea samples.
PubMed:Bioavailability of xenobiotics in the soil environment.
PubMed:Development of a GC x GC-TOFMS method using SPME to determine volatile compounds in cacao beans.
PubMed:Quantitative inference of cellular parameters from microfluidic cell culture systems.
PubMed:Development of a positive pressure driven micro-fabricated liquid chromatographic analyzer through rapid-prototyping with poly(dimethylsiloxane) Optimizing chromatographic efficiency with sub-nanoliter injections.
PubMed:Pesticide analysis in tomatoes by solid-phase microextraction and micellar electrokinetic chromatography.
PubMed:Electrochemical detection of cardiac troponin I using a microchip with the surface-functionalized poly(dimethylsiloxane) channel.
PubMed:Construction of a dimethyl sulfoxide sensor based on dimethyl sulfoxide reductase immobilized on a au film electrode.
PubMed:A microfluidic system for evaluation of antioxidant capacity based on a peroxyoxalate chemiluminescence assay.
PubMed:Effects of dissolved organic matter on permethrin bioavailability to Daphnia species.
PubMed:Immunosensing of Staphylococcus enterotoxin B (SEB) in milk with PDMS microfluidic systems using reinforced supported bilayer membranes (r-SBMs).
PubMed:Determination of pyrethroid residues in tobacco by means of solid phase microextraction and GC/MS with the aid of ultrasonic assisted extraction using water as extracting solvent.
PubMed:Comparison of volatile concentrations in hand-squeezed juices of four different lemon varieties.
PubMed:Ochratoxin a determination in beer by solid-phase microextraction coupled to liquid chromatography with fluorescence detection: a fast and sensitive method for assessment of noncompliance to legal limits.
PubMed:Optimization of a solid-phase microextraction procedure for the determination of herbicides by micellar electrokinetic chromatography.
PubMed:Tequila volatile characterization and ethyl ester determination by solid phase microextraction gas chromatography/mass spectrometry analysis.
PubMed:Yield effects on 2-methoxy-3-isobutylpyrazine concentration in cabernet sauvignon using a solid phase microextraction gas chromatography/mass spectrometry method.
PubMed:Solid-phase microextraction coupled to gas chromatography/mass spectrometry for determining polycyclic aromatic hydrocarbon-micelle partition coefficients.
PubMed:Silylation of acrylamide for analysis by solid-phase microextraction/gas chromatography/ion-trap mass spectrometry.
PubMed:Solid-phase microextraction coupled with high-performance liquid chromatography for the analysis of heterocyclic aromatic amines.
PubMed:Identification and sensory evaluation of volatile compounds in oxidized porcine liver.
PubMed:Analysis of aldehydes in beer using solid-phase microextraction with on-fiber derivatization and gas chromatography/mass spectrometry.
PubMed:Dynamic viscoelastic and tensile properties of gluten and glutenin gels of common wheats of different strength.
PubMed:Analysis of volatile compounds released during the grinding of roasted coffee beans using solid-phase microextraction.
PubMed:Headspace solid phase microextraction applied to the analysis of organophosphorus insecticides in strawberry and cherry juices.
PubMed:Headspace sorptive extraction (HSSE), stir bar sorptive extraction (SBSE), and solid phase microextraction (SPME) applied to the analysis of roasted Arabica coffee and coffee brew.
PubMed:Amperometric determination of acetic acid with a trienzyme/poly(dimethylsiloxane)-bilayer-based sensor.
PubMed:Focused microwave assistance for extracting some pesticide residues from strawberries into water before their determination by SPME/HPLC/DAD.
PubMed:Changes in the volatile profile of oats induced by processing.
PubMed:Integrated plastic microfluidic devices with ESI-MS for drug screening and residue analysis.
PubMed:Flavor threshold for acetaldehyde in milk, chocolate milk, and spring water using solid phase microextraction gas chromatography for quantification.
PubMed:Solid-phase microextraction of volatile components from natural grassland plants.
PubMed:Evaluation of Solid-Phase Microextraction for Analysis of Volatile Metabolites Produced by Staphylococci.
PubMed:Multi-residue methodology for pesticide screening in wines.
PubMed:Solid-phase microextraction: a promising technique for sample preparation in environmental analysis.
PubMed:Solid-phase microextraction method development for headspace analysis of volatile flavor compounds.
PubMed:Analysis of volatile contaminants in vegetable oils by headspace solid-phase microextraction with carboxen-based fibres.
PubMed:Application of solid-phase microextraction to the headspace gas chromatographic analysis of halogenated volatiles in selected foods.
 
Notes:
None found
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