EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

mercaptoacetic acid sodium salt
acetic acid, 2-mercapto-, sodium salt (1:1)

Supplier Sponsors

CAS Number: 367-51-1Picture of molecule3D/inchi
Other(deleted CASRN):12773-25-0
ECHA EINECS - REACH Pre-Reg:206-696-4
FDA UNII: D94M78P69V
Nikkaji Web:J5.705C
Beilstein Number:4569109
MDL:MFCD00043386
Molecular Weight:114.09907928
Formula:C2 H3 Na O2 S
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:reducing agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
depilatories
hair straightening agents
hair waving agents
reducing agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Mercaptoacetic acid, sodium salt >98%
BRUNO BOCK
Sodium Thioglycolate
Odor: characteristic
Use: Sodium Thioglycolate is produced by BRUNO BOCK and EVANS CHEMETICS in various concentrations. A low odor version with a concentration of 46 % is also available
EMD Millipore
For experimental / research use only.
Sodium Thioglycolate
Endeavour Specialty Chemicals
Mercaptoacetic acid sodium salt
Speciality Chemical Product Groups
Glentham Life Sciences
Sodium thioglycolate, 98%
Robinson Brothers
Mercaptoacetic acid sodium salt
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
Sodium thioglycolate
Sigma-Aldrich: Sigma
For experimental / research use only.
Sodium thioglycolate ≥96.5% (iodometric)
TCI AMERICA
For experimental / research use only.
Sodium Thioglycolate >93.0%(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LDLo 500 mg/kg
BEHAVIORAL: TREMOR GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 296, 1956.

intraperitoneal-mouse LD50 200 mg/kg
National Technical Information Service. Vol. AD277-689

intravenous-mouse LD50 422 mg/kg
Japanese Journal of Antibiotics. Vol. 38, Pg. 137, 1985.

oral-mouse LD50 504 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 296, 1956.

unreported-mouse LD50 8200 ug/kg
Canadian Journal of Technology. Vol. 34, Pg. 21, 1956.

intravenous-rabbit LDLo 100 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 35, Pg. 343, 1929.

intraperitoneal-rat LD50 126 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 296, 1956.

Dermal Toxicity:
subcutaneous-mouse LD50 293 mg/kg
Japanese Journal of Antibiotics. Vol. 41, Pg. 105, 1988.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
reducing agents
Recommendation for mercaptoacetic acid sodium salt usage levels up to:
 not for fragrance use.
 
Recommendation for mercaptoacetic acid sodium salt flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):367-51-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23690444
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
sodium;2-sulfanylacetate
Chemidplus:0000367511
EPA/NOAA CAMEO:hazardous materials
RTECS:AI7700000 for cas# 367-51-1
 
References:
 sodium;2-sulfanylacetate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:367-51-1
Pubchem (cid):23690444
Pubchem (sid):134974311
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2930.90.4950
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 depilating agents
 reducing agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acetic acid, 2-mercapto-, sodium salt (1:1)
 acetic acid, mercapto-, monosodium salt
 mercaptoacetic acid monosodium salt
 mercaptoacetic acid sodium salt
 mercaptoacetic acid, sodium salt
 sodium 2-mercatoethanoate
 sodium 2-sulfanylacetate
 sodium mercaptoacetate
 sodium sulfanylacetate
 sodium thioacetate
 sodium;2-sulfanylacetate
 sodiumthioglycolate
 thioglycolate sodium
 thioglycolic acid sodium salt
 thioglycolic acid, sodium salt
 thioglycollic acid, sodium salt
 

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PubMed:Developmental toxicity evaluation of sodium thioglycolate administered topically to Sprague-Dawley (CD) rats and New Zealand White rabbits.
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PubMed:False positiveness in a choline acetyltransferase assay caused by nonionic reducing reagents.
PubMed:[Screening for the antagonizing agents against lethal toxicity of neocarzinostatin. I. Inhibitory effects of various drugs on the toxicity of neocarzinostatin in vitro and in vivo].
PubMed:Pseudophosphorylation of the smooth muscle 20 000 dalton myosin light chain. An artifact due to protein modification.
PubMed:Procedure for increased recovery of Campylobacter jejuni from inoculated unpasteurized milk.
PubMed:Lactoferrin and transferrin fragments react with nitrite to form an inhibitor of Bacillus cereus spore outgrowth.
PubMed:Enhanced recovery of injured Escherichia coli by compounds that degrade hydrogen peroxide or block its formation.
PubMed:[Neutral and basic compounds present in gases produced by Clostridium sporogenes, Plectridium putrificum and Plectridium glycolicum cultured under vacuum in sodium thioglycolate glucose broth].
PubMed:[Neutral and basic compounds present in gases produced by Clostridium histolyticum, Clostridium hastiforme and Clostridium ghoni cultured under vacuum in sodium thioglycolate glucose broth].
PubMed:[Detection of "Clostridium difficile" on minimal and selective medium and by immunofluorescence antibody staining (author's transl)].
PubMed:Nuclear basic protein changes during spermiogenesis in the longnose skate and the spiny dogfish.
PubMed:Efficacy of inactivators against 14 disinfectant substances.
PubMed:Effect of reducing agents on oxidation-reduction potential and the outgrowth of Clostridium botulinum type E spores.
PubMed:[Initiation of germination of Clostridium difficile spores by lysozyme].
PubMed:Inhibition and killing of oral bacteria by silver ions generated with low intensity direct current.
PubMed:[Effect of the redox potential on the growth of aerobic microorganisms].
PubMed:Release of oxytocin from the rat posterior pituitary lobe incubated in situ and from the hypothalamic end of the cut pituitary stalk.
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PubMed:Recovery of spores of Clostridium botulinum in yeast extract agar and pork infusion agar after heat treatment.
PubMed:[Dissolution of polyhedra of the nuclear polyhedrosis virus of the leatherjacket Tipula paludosa MEIG. Ultrastructural study of the virion (author's transl)].
PubMed:Examination of various cell culture techniques for co-incubation of virulent Treponema pallidum (Nichols I strain) under anaerobic conditions.
PubMed:Significant enhancement of T-strain mycoplasmal growth on supplemented Shepard's A6 differential agar.
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PubMed:[Composition of the gases emitted by Clostridium sporogenes, Clostridium bifermentans, Clostridium sordelii, Clostridium oedematiens and Plectridium putrificum cultivated in medium with sodium thioglycolate, under vacuum, after alkalinization of the culture medium].
PubMed:[Composition of gases emitted by Clostridium histolyticum cultivated on sodium thioglycolate media in a vaccuum, after alkalinisation of the medium at the end of culturing].
PubMed:[Composition of gases emitted by Clostridium aerofoetidum and Clostridium fallax cultured in a medium containing sodium thioglycolate in a vacuum, after alkalinization of the medium for cultures].
PubMed:[Sodium thioglycolate and hypothalamo-neurohypophysial hormones].
PubMed:Chemically defined medium for growth and sporulation of Clostridium perfringens.
PubMed:[Composition of the gases given off by Clostridium septicum, Clostridium chauvoei and Welchia perfringens cultured in a sodium thioglycolate medium under vacuum after alkalinization of the medium at the end of cultivation].
PubMed:[Comparative study of the composition of gases emitted by Clostridium botulinum types A and B cultured in sodium thioglycolate medium].
PubMed:Enrichment, isolation, and cultural characteristics of marine strains of Clostridium botulinum type C.
PubMed:Callus and its keratin before and after treatment with acid sodium thioglycolate. A study by scanning and conventional electron microscopy.
PubMed:Conditions Affecting Germination of Clostridium botulinum 62A Spores in a Chemically Defined Medium.
PubMed:[A comparative study of gas produced by 11 anaerobic gas gangrene bacilli grown on a sodium thioglycolate medium, in a vacuum].
PubMed:[Gas liberated by Clostridium oedematiens cultivated on sodium thioglycolate medium in a vacuum].
PubMed:[Comparative study of gases emitted by Clostridium septicum and Clostridium chauvoei cultivated on sodium thioglycolate medium].
PubMed:[Composition of gases emitted by Clostridium erofoetidum and by Clostridium fallax cultivated in sodium thioglycolate culture medium].
PubMed:[Composition of gas released by Welchia perfringens and by Plectridium putrificum cultivated in sodium thioglycolate medium].
PubMed:Comparative studies on the inactivation of vasopressin by human pregnancy plasma and sodium thioglycolate.
PubMed:Improved medium for sporulation of Clostridium perfringens.
PubMed:[A study of the nature of the radioprotective effect of cysteamine and sodium thioglycolate].
PubMed:Sporulation of Clostridium perfringens in a modified medium and selected foods.
PubMed:Effect of sodium chloride and pH on the outgrowth of spores of type E Clostridium botulinum at optimal and suboptimal temperatures.
PubMed:FACTORS AFFECTING THE DEVELOPMENT OF CLOSTRIDIUM BOTULINUM IN WHOLE MILK.
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PubMed:[Toxic and allergic reactions to organic sulfur compounds in permanent-wave preparations. III. Investigations of the comparative tolerance of ammonium- and sodium-thioglycolate solutions].
PubMed:Some aspects of the absorption, distribution and excretion of sodium thioglycolate.
PubMed:[Sodium thioglycolate bouillon, a liquid medium for the culture of obligate and facultative anaerobes].
PubMed:The inactivation of influenza virus by mercurials and the reactivation of sodium thioglycolate and BAL.
PubMed:The inactivation of influenza virus by mercurials and reactivation by sodium thioglycolate and BAL.
PubMed:STUDIES ON THE MECHANISM OF ANTIBACTERIAL ACTION OF 2-METHYL-1,4-NAPHTHOQUINONE.
 
Notes:
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