EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

disodium pyrophosphate
pyrophosphoric acid, disodium salt

Sponsors

Name:disodium [hydroxy(oxido)phosphoryl] hydrogen phosphate
CAS Number: 7758-16-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-835-0
FDA UNII:H5WVD9LZUD
MDL:MFCD00014246
Molecular Weight:221.93740256
Formula:H2 Na2 O7 P2
NMR Predictor:Predict (works with chrome or firefox)
Category:raising agents, buffering agents, sequestrants, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
182.1087 Sodium acid pyrophosphate View-review
JECFA Food Additive: Disodium Pyrophosphate
GSFA Codex: Disodium diphosphate (450(i))
FDA Mainterm: SODIUM ACID PYROPHOSPHATE
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.180 Self-rising flour.


FDA PART 161 -- FISH AND SHELLFISH
Subpart B--Requirements for Specific Standardized Fish and Shellfish
Sec. 161.190 Canned tuna.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1087 Sodium acid pyrophosphate.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -3.420 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: anticorrosive agents
buffering agents
chelating agents
 
Suppliers:
American International Chemical, LLC.
SODIUM ACID PYROPHOSPHATE FCC POWDER
Foodchem International
Sodium Acid Pyrophosphate
Graham Chemical
Sodium Acid Pyrophosphate
Prinova
Sodium Acid Pyrophosphate
Santa Cruz Biotechnology
For experimental / research use only.
Sodium pyrophosphate dibasic
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium pyrophosphate dibasic practical grade
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2650 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957.

intravenous-mouse LD50 59 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957.

intraperitoneal-mouse LD50 1000 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 24, 1957.

Dermal Toxicity:
subcutaneous-mouse LD50 480 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957.

skin-rabbit LD > 300 mg/kg
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 47, 1990.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: raising agents, buffering agents, sequestrants, acidity regulators
Recommendation for disodium pyrophosphate usage levels up to:
 not for fragrance use.
 
Recommendation for disodium pyrophosphate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the safety evaluation of the active substances, iron, polyethyleneglycol, disodium pyrophosphate, monosodium phosphate and sodium chloride for use in food contact materials
View page or View pdf
Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
EPI System: View
NLM Hazardous Substances Data Bank:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):7758-16-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24451
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
disodium [hydroxy(oxido)phosphoryl] hydrogen phosphate
Chemidplus:0007758169
RTECS:UX6475000 for cas# 7758-16-9
 
References:
 disodium [hydroxy(oxido)phosphoryl] hydrogen phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7758-16-9
Pubchem (cid):24451
Pubchem (sid):134989989
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
FooDB:FDB014651
Export Tariff Code:2835.39.5000
Haz-Map:View
Household Products:Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
grades: technical; food; fcc. hexahydrate
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 diphosphoric acid, disodium salt
 disodium [hydroxy(oxido)phosphoryl] hydrogen phosphate
 disodium acid pyrophosphate
 disodium dihydrogen diphosphate
 disodium dihydrogen pyrophosphate
 disodium dihydrogenpyrophosphate
 disodiumpytophosphate
 phosphonate, oxybis-, disodium salt
 phosphonate, P,P'-oxybis-, sodium salt (1:2)
 pyrophosphoric acid disodium salt
 pyrophosphoric acid, disodium salt
 SAPP
 sodium acid pyrophosphate
 
 
Notes:
Employed in food processing as a preservative, emulsifying agent and leavening agent Disodium pyrophosphate or sodium acid pyrophosphate is a buffering and chelating agent, with many food and industrial uses. (Wikipedia)
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