• Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email:Technical Services
      US Email:Sales
      US Voice:(973) 740-2300
      US Fax:(973) 740-1839
      Product(s):
      2-BUTOXYETHANOL, Kosher
       
 
2-butoxyethanol
  • Home
  • Suppliers
  • Organoleptics
      • Organoleptic Properties
  • Properties
      • Physical Properties
        Appearance :colorless to pale yellow clear liquid (est)
        Assay : 95.00 to 100.00 % 
        Food Chemicals Codex Listed :No
        Specific Gravity :0.89900 to 0.90500 @  25.00 °C.
        Pounds per Gallon - (est). : 7.481 to  7.531
        Refractive Index :1.41600 to 1.42200 @  20.00 °C.
        Melting Point : -74.80 °C. @ 760.00 mm Hg
        Boiling Point : 168.40 °C. @ 760.00 mm Hg
        Vapor Pressure :0.880000 mm/Hg @ 25.00 °C.
        Vapor Density :4.1 ( Air = 1 )
        Flash Point : 140.00 °F. TCC ( 60.00 °C. )
        logP (o/w) : 0.830
  • Safety
      • Safety Information
        Most important hazard(s) :Xn - Harmful.
          R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
        R 36/38 - Irritating to skin and eyes.
        S 02 - Keep out of the reach of children.
        S 20/21 - When using do not eat, drink or smoke.
        S 23 - Do not breath vapour.
        S 24/25 - Avoid contact with skin and eyes.
        S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
        S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
        Oral/Parenteral Toxicity : 
          gavage-rat LD50  [sex: M] 1480 mg/kg
        (Smyth et al., 1941)

        oral-rat LD50  1174 mg/kg
        (BASF, 1956)

        oral-rat LD50  620 mg/kg
        (Rowe & Wolf, 1982)

        oral-rat LD50  [sex: M,F] 2800 mg/kg
        (Carpenter et al., 1956)

        gavage-rat LD50  [sex: M] 2680 mg/kg
        (Myers & Homan, 1980)

        oral-rat LD50  470 mg/kg
        (Wolf, 1959)

        gavage-rat LD50  [sex: M] 2800. mg/kg
        (Weil & Wright, 1967)

        gavage-rat LD50  [sex: M] 1590 mg/kg
        (Moreno, 1976l)

        gavage-rat LD50  [sex: M] 7500 mg/kg
        (Moreno, 1976l)

        oral-rat LD50  1746 mg/kg
        (Eastman Kodak Co., 1989

        gavage-rat LD50  [sex: M] 7292 mg/kg
        (Eastman Kodak Co., 1984)

        oral-mouse LD50  1230 mg/kg
        (Carpenter et al., 1956)

        oral-mouse LD50  1700 mg/kg
        (Dow Chemical Company, 1982a

        oral-mouse LD50  1519 mg/kg
        (Eastman Kodak Co., 1989)

        gavage-mouse LD50  [sex: M] 2406 mg/kg
        (Eastman Kodak Co., 1984)

        oral-rabbit LD50  [sex: M] 370 mg/kg
        (Carpenter et al., 1956)

        oral-guinea pig LD50  [sex: M,F] 1200 mg/kg
        (Carpenter et al., 1956)

        gavage-guinea pig LD50  [sex: M,F] 1200 mg/kg
        (Smyth et al., 1941)

        oral-guinea pig LD50  1200 mg/kg
        GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: GENERAL ANESTHETIC KIDNEY, URETER, AND BLADDER: OTHER CHANGES
        Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

        unreported-mammal (species unspecified) LD50  1500 mg/kg
        Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.

        intraperitoneal-mouse LD50  536 mg/kg
        Shell Chemical Company. Unpublished Report. Vol. -, Pg. 2, 1961.

        intravenous-mouse LD50  1130 mg/kg
        AMA Archives of Industrial Health. Vol. 14, Pg. 114, 1956.

        oral-mouse LD50  1230 mg/kg
        BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
        AMA Archives of Industrial Health. Vol. 14, Pg. 114, 1956.

        unreported-mouse LD50  1050 mg/kg
        LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT
        Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(11), Pg. 7, 1976.

        intraperitoneal-rabbit LD50  220 mg/kg
        "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.

        intravenous-rabbit LD50  252 mg/kg
        AMA Archives of Industrial Health. Vol. 14, Pg. 114, 1956.

        oral-rabbit LD50  300 mg/kg
        Yakkyoku. Pharmacy. Vol. 32, Pg. 1241, 1981.

        intraperitoneal-rat LD50  220 mg/kg
        "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.

        intravenous-rat LD50  307 mg/kg
        AMA Archives of Industrial Health. Vol. 14, Pg. 114, 1956.

        oral-rat LD50  470 mg/kg
        Dow Chemical Company Reports. Vol. MSD-46

        unreported-rat LD50  917 mg/kg
        BEHAVIORAL: EXCITEMENT BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
        Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(11), Pg. 7, 1976.

        Dermal Toxicity : 
          skin-guinea pig LD50 230 ul/kg
        Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.

        skin-rabbit LD50 220 mg/kg
        Dow Chemical Company Reports. Vol. MSD-46

        subcutaneous-mouse LDLo 500 mg/kg
        Journal of Pharmacology and Experimental Therapeutics. Vol. 42, Pg. 355, 1931.

        Inhalation Toxicity : 
          inhalation-rat LC50 450 ppm/4H
        BEHAVIORAL: ATAXIA
        Toxicology and Applied Pharmacology. Vol. 68, Pg. 405, 1983.

        inhalation-mouse LC50 700 ppm/7H
        LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ANALGESIA KIDNEY, URETER, AND BLADDER: HEMATURIA
        Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 157, 1943.

        inhalation-guinea pig LC > 633 ppm/1H
        National Technical Information Service. Vol. OTS0572613

        inhalation-human TCLo 100 ppm
        SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
        Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 50, 1974.

        inhalation-human TCLo 195 ppm/8H
        GASTROINTESTINAL: NAUSEA OR VOMITING
        AMA Archives of Industrial Health. Vol. 14, Pg. 114, 1956.

  • Safety in Use
      • Safety in Use Information
        Category :sanitizing agents for food processing equipment
        Maximised Survey-derived Daily Intakes (MSDI-EU) :0.0012 (μg/capita/day)
        Modified Theoretical Added Maximum Daily Intake (mTAMDI) :3900 (μg/person/day)
        Threshold of Concern :540 (μg/person/day)
        Structure Class :II
        Recommendation for 2-butoxyethanol fragrance usage levels up to :
         not for fragrance use.
        Recommendation for 2-butoxyethanol flavor usage levels up to :
         not for flavor use.
         
        Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
        Note : mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
         average usage mg/kgmaximum usage mg/kg
        Dairy products, excluding products of category 02.0 (01.0) : 7.0000035.00000
        Fats and oils, and fat emulsions (type water-in-oil) (02.0) : 5.0000025.00000
        Edible ices, including sherbet and sorbet (03.0) : 10.0000050.00000
        Processed fruit (04.1) : 7.0000035.00000
        Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) : --
        Confectionery (05.0) : 10.0000050.00000
        Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) : 5.0000025.00000
        Bakery wares (07.0) : 10.0000050.00000
        Meat and meat products, including poultry and game (08.0) : 2.0000010.00000
        Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) : 2.0000010.00000
        Eggs and egg products (10.0) : --
        Sweeteners, including honey (11.0) : --
        Salts, spices, soups, sauces, salads, protein products, etc. (12.0) : 5.0000025.00000
        Foodstuffs intended for particular nutritional uses (13.0) : 10.0000050.00000
        Non-alcoholic ("soft") beverages, excl. dairy products (14.1) : 5.0000025.00000
        Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) : 10.0000050.00000
        Ready-to-eat savouries (15.0) : 20.00000100.00000
        Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) : 5.0000025.00000
  • Safety References
      • Safety References
        European Food Safety Athority(efsa) :Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
        European Food Safety Authority (EFSA) reference(s) :
        Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000):page or pdf
        Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC):page or pdf
        Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab):page or pdf
        Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009):page or pdf
        Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30:page or pdf
        Scientific Opinion on Flavouring Group Evaluation 10, Revision 3 (FGE.10Rev3): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30:page or pdf
        EPI System :View
        Chemicalize.org :Calculate predicted properties
        IUCLID Chemical Data Sheet :View
        EPA-Iris :IRIS
        NIOSH International Chemical Safety Cards :search
        NIOSH Pocket Guide :search
        NLM Hazardous Substances Data Bank :Search
        Chemical Carcinogenesis Research Information System :Search
        Cancer Citations :Search
        Toxicology Citations :Search
        Carcinogenic Potency Database :Search
        Env. Mutagen Info. Center :Search
        NLM Developmental and Reproductive Toxicity :Search
        National Toxicology Program :Search
        EPA Substance Registry Services (TSCA) :111-76-2
        EPA ACToR :Toxicology Data
        SCCNFP :opinion
        WISER :UN 2810
        WGK Germany :1
         2-butoxyethanol
        DTP/NCI :60759
        Chemidplus :0000111762
        EPA/NOAA CAMEO :hazardous materials
        RTECS :111-76-2
2-butoxyethanol (Click)
CAS Number : 111-76-2
ESIS EC# (EINECS) :203-905-0
EU CLP/GHS Annex VI Index# :603-014-00-0
Beilstein Number :1732511
MDL :MFCD00002884
CoE Number :10182
XlogP3 :0.80 (est)
Molecular Weight :118.17598000
Formula :C6 H14 O2
BioActivity Summary :listing
NMR Predictor :Predict
Category :sanitizing agents for food processing equipment
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
Google Scholar : Search Google Books : Search
Google Scholar : with word "volatile"Search Google Scholar : with word "flavor"Search
Google Scholar : with word "odor"Search 
Google Patents : Search US Patents : Search
EU Patents : Search IBM Patents : Obtain
Pubchem Patents:Search
PubMed : SearchNCBI : Search
Flavis Number :02.242 (Old site)
EU SANCO Food Flavourings :02.242  2-butoxyethan-1-ol

FDA Mainterm : ETHYLENE GLYCOL MONOBUTYL ETHER
FDA Regulation :FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.315 Chemicals used in washing or to assist in the peeling of fruits and vegetables.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.210 Defoaming agents used in the manufacture of paper and paperboard.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1650 Polysulfide polymer-polyepoxy resins.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.
click on the picture(s) below to
interact with the 3D model
Picture of molecule
2-butoxyethanol
Synonyms :
2-butoxy ethanol
2-butoxy-1-ethanol
2-N-butoxy-1-ethanol
2-butoxyethan-1-ol
 butoxyethanol
2-N-butoxyethanol
N-butoxyethanol
N-butoxyethanol sodium salt
 butyl cellosolve
N-butyl cellosolve
monobutyl ether of ethylene glycol
monobutyl ethylene glycol ether
 butyl glycol
monobutyl glycol ether
 butyl oxitol
 butylcellosolve
 dowanol EB
 EGBE
 ek tasolve EB solvent
 ektasolve EB
 ethanol, 2-butoxy-
 ethylene glycol butyl ether
 ethylene glycol mono butyl ether
 ethylene glycol mono-N-butyl ether
 ethylene glycol monobutyl ether
 ethylene glycol N-butyl ether
 ethyleneglycol monobutyl ether
 glycol ether EB
 glycol monobutyl ether
2-hydroxyethyl N-butyl ether
 jeffersol EB
Soluble in :
 alcohol
 water, 1.00E+06 mg/L @ 20 °C (exp)
Stability :
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2014 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy