EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

oxybenzone
2-hydroxy-4-methoxybenzophenone

Supplier Sponsors

Name:(2-hydroxy-4-methoxyphenyl)-phenylmethanone
CAS Number: 131-57-7Picture of molecule3D/inchi
Other:14375-37-2
ECHA EINECS - REACH Pre-Reg:205-031-5
FDA UNII:95OOS7VE0Y
Nikkaji Web:J5.562J
Beilstein Number:1913145
MDL:MFCD00008387
XlogP3:3.60 (est)
Molecular Weight:228.24724000
Formula:C14 H12 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:cosmetic UV absorber
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:2-hydroxy-4-methoxybenzophenone
FDA Mainterm (IAUFC):131-57-7 ; OXYBENZONE

 
Physical Properties:
Appearance:pale yellow fine crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 65.50 °C. @ 760.00 mm Hg
Boiling Point: 370.00 to 371.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000005 mmHg @ 25.00 °C. (est)
Flash Point: 285.00 °F. TCC ( 140.50 °C. ) (est)
logP (o/w): 3.790
Soluble in:
 alcohol
 water, 68.6 mg/L @ 25 °C (exp)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: uv absorbers
uv filters
 
Suppliers:
Aceto
Oxybenzone USP (2- Hydrocy-4-Methoxy Benzophenone)
American International Chemical, LLC.
Oxybenzone USP
BOC Sciences
For experimental / research use only.
Oxybenzone >98%
Odor: characteristic
Use: 2-Hydroxy-4-methoxybenzophenone (benzophenone-3) is commonly employed as broad-band UV-filter in sunscreen cosmetic products. It protects skin from the deleterious effects of the sun.
ECSA Chemicals
Benzophenone-3
Company Profile
Galaxy Surfactants
GalSORB Benzophenone-3
Moellhausen
NEO HELIOPAN BB
OQEMA
LanCos UVB-3
Penta International
3-BENZOPHENONE
Sigma-Aldrich
For experimental / research use only.
2-Hydroxy-4-methoxybenzophenone certified reference material, TraceCERT®
Sinoway Industrial
For experimental / research use only.
2-Hydroxy-4-methoxy benzophenone(UV9)
Symrise
Neo Heliopan® BB
Life Essentials - UV Protection
Odor: characteristic
Use: Neo Heliopan® BB is an effective oil-soluble broad spectrum absorber with max. protection in the short-wave UVB and UVA spectra (UVB at approx. 286 nm, UVA at approx. 325 nm).
TRI-K Industries
GalSorb Benzophenone-3
Odor: characteristic
Use: The backbone of many sunscreens & sun protection products, Benzophenone-3 offers UVB protection and some absorbtion in the short UVA II region (320-342 nm). This product is oil soluble.
Vigon International
Neo Heliopan BB (Benzophenone-3)
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 300 mg/kg
National Technical Information Service. Vol. AD277-689

oral-rat LD50 7400 mg/kg
Journal of the American College of Toxicology. Vol. 2(5), Pg. 35, 1983.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic UV absorber
Recommendation for oxybenzone usage levels up to:
 not for fragrance use.
 
Recommendation for oxybenzone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):131-57-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :4632
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(2-hydroxy-4-methoxyphenyl)-phenylmethanone
Chemidplus:0000131577
EPA/NOAA CAMEO:hazardous materials
RTECS:DJ1575000 for cas# 131-57-7
 
References:
 (2-hydroxy-4-methoxyphenyl)-phenylmethanone
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:131-57-7
Pubchem (cid):4632
Pubchem (sid):134973727
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C14285
HMDB (The Human Metabolome Database):HMDB15497
Haz-Map:View
Household Products:Search
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 u.v. absorbers
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 advastab 45
 benzophenone-3
 benzophenone, 2-hydroxy-4-methoxy-
2-benzoyl-5-methoxyphenol
 cyasorb UV 9
 eusolex 4360
2-hydroxy-4-methoxy benzophenone
2-hydroxy-4-methoxy-benzophenone
(2-hydroxy-4-methoxy-phenyl)-phenyl-methanone
2-hydroxy-4-methoxybenzophenone
2-hydroxy-4-methoxyphenyl phenyl ketone
(2-hydroxy-4-methoxyphenyl)-phenylmethanone
(2-hydroxy-4-methoxyphenyl)(phenyl)methanone
(2-hydroxy-4-methoxyphenyl)phenylmethanone
 methanone, (2-hydroxy-4-methoxyphenyl)phenyl-
4-methoxy-2-hydroxybenzophenone
 neo heliopan BB (Symrise)
 presun 15
 spectra-sorb UV 9
 syntase 62
 uvinul M-40
 

Articles:

PubMed:Photoprotection: part II. Sunscreen: development, efficacy, and controversies.
PubMed:Quantification and in situ localisation of abcb1 and abcc9genes in toxicant-exposed sea urchin embryos.
PubMed:Interoperability of 300 watt and 150 watt xenon arc solar simulators in sun protection factor and in UVA protection factor clinical testing.
PubMed:Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitization.
PubMed:Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography.
PubMed:Identification and determination butylmethoxydibenzoylmethane in the presence benzophenone-3 and ethylhexylmethoxycinnamate in suncare preparation.
PubMed:Safety evaluation of benzophenone-3 after dermal administration in rats.
 
Notes:
None found
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