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sodium thiosulfate
thiosulfuric acid (H2S2O3) sodium salt (1:2)

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CAS Number: 7772-98-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-867-5
Nikkaji Web:J47.986A
Molecular Weight:158.10713856
Formula:Na2 O3 S2
NMR Predictor:Predict (works with chrome or firefox)
Category:antibrowning agents, antioxidants, preservatives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1807 Sodium thiosulfate View - review
JECFA Food Additive: Sodium Thiosulfate
GSFA Codex: Sodium thiosulfate (539)
DG SANTE Food Contact Materials:sodium thiosulfate
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -0.428 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: reducing agents
Allan Chemical
Sodium Thiosulfate
American Elements
Sodium Thiosulfate Anhydrous 99%
Odor: characteristic
Use: Sodium Thiosulfate Anhydrous is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Sodium Thiosulfate
For experimental / research use only.
Sodium Thiosulfate
BOC Sciences
For experimental / research use only.
Sodium Thiosulfate 95%
Charkit Chemical
Covalent Chemical
Sodium Thiosulfate
ECSA Chemicals
Sodium Thiosulphate
Company Profile
Graham Chemical
Sodium Thiosulfate
Krunal Group
Sodium Thiosulphate
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
Sodium thiosulfate
Shiva Chemicals and Pharmaceuticals
Sodium Thiosulfate
For experimental / research use only.
Sodium Thiosulfate ReagentPlus®, 99%
Silver Fern Chemical
Sodium Thiosulfate
Odor: characteristic
Use: Sodium thiosulfate is used in photography, chrome tanning, bleaching, paper manufacturing, gold and silver extraction, and as an antidote for cyanide poisoning.
Wedor Corporation
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 5200 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 53, Pg. 404, 1957.

intravenous-rat LD > 2500 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 25, Pg. 297, 1925.

Dermal Toxicity:
subcutaneous-frog LDLo 6000 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.

subcutaneous-rabbit LDLo 4000 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.

Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: antibrowning agents, antioxidants, preservatives
Recommendation for sodium thiosulfate usage levels up to:
 not for fragrance use.
Recommendation for sodium thiosulfate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Daily Med:search
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):7772-98-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24477
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
disodium dioxido-oxo-sulfanylidene-?6-sulfane
 disodium dioxido-oxo-sulfanylidene-?6-sulfane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7772-98-7
Pubchem (cid):24477
Pubchem (sid):134990148
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
Household Products:Search
RSC Learn Chemistry:View
grades: technical; crystals; granulated; photographic; c.p.; u.s.p.; f.c.c.
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 disodium dioxido-oxo-sulfanylidene-lamda6-sulfane
 disodium sulfurothioate
 disodium thiosulfate
 disodium thiosulphate
 sodium oxide sulfide
 sodium oxide sulfide (Na2S2O3)
 sodium thiosulfate (Na2S2O3)
 sodium thiosulfate anhydrous reagent
 sodium thiosulfate anhydrous reagent grade
 sodium thiosulphate
 sodium thiosulphate (Na2S2O3)
 thiosulfuric acid (H2S2O3) sodium salt (1:2)
 thiosulfuric acid (H2S2O3), disodium salt
 thiosulfuric acid disodium salt
 thiosulfuric acid, disodium salt


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PubMed:The effect of sodium thiosulfate administration on nephrocalcinosis in a rat model.
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PubMed:Validation of thiosulfate for neutralization of acidified sodium chlorite in microbiological testing.
PubMed:Multiresidue liquid chromatographic method for determining residues of mono- and dibasic penicillins in bovine muscle tissues.
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PubMed:Nitroprusside intoxication: protection of alpha-ketoglutarate and thiosulphate.
PubMed:Sodium nitroprusside-induced cyanide intoxication and prevention with sodium thiosulfate prophylaxis.
PubMed:Treatment of cyanide poisoning.
PubMed:A resuscitation/selection system for rapid determination of Salmonella in foods.
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PubMed:Liquid chromatographic-atomic absorption spectrophotometric method for determination of methyl mercury in seafood: collaborative study.
PubMed:Detection of salmonellas in confectionery products by conductance.
PubMed:Utilization by sheep of whole shelled corn impregnated with urea, calcium, potassium and sulfur.
PubMed:[Disorders of microcirculation in food poisoning].
do not confuse synonym sodium hyposulfite with sodium hyposulfite, synonym for di-na salt of dithionous acid. Formulation aid and reducing agent used in alcoholic beverages and table salt
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